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VITATDLEVRAGARILLAPDGPDLRVQPGDRIGLVGRNGAGKTTTLRILAGEVEPYAGSVTRAGEIGYLP QDPKVGDLDVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDRAIRRYGQLEERFVALGGYGAESE AGRICASLGLPERVLTQRLRTLSGGQRRRVELARILFAASESGAGNSTTLLLDEPTNHLDADSLGWLRDF LRLHTGGLVVISHNVDLVADVVNKVWFLDAVRGQVDVYNMGWQRYVDARATDEQRRIRERANAERKAAAL RAQAAKLGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKFPTPAACGRTPLVANGLGKTYGSLEV FTGVDLAIDRGSRVVILGLNGAGKTTLLRLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENV RHAAPDAGEQDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTANVLLLDEPTNNLDPASREQ VLDALRSYRGAVVLVTHDPGAAAALGPQRVVLLPDGTEDYWSDEYRDLIELA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1473 | - | - | 100% (542) | PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER |
| M. tuberculosis H37Rv | Rv2477c | - | 3e-59 | 31.15% (504) | putative ABC transporter ATP-binding protein |
| M. tuberculosis H37Rv | Rv1668c | - | 4e-29 | 30.53% (380) | macrolide-transport ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1508 | - | 0.0 | 100.00% (542) | macrolide ABC transporter ATP-binding protein |
| M. gilvum PYR-GCK | Mflv_3668 | - | 0.0 | 86.72% (542) | ABC transporter related |
| M. leprae Br4923 | MLBr_01816 | - | 0.0 | 88.07% (545) | ABC transporter ATP-binding protein, possibly in EF-3 subfamily |
| M. abscessus ATCC 19977 | MAB_2736c | - | 0.0 | 84.32% (542) | macrolide ABC transporter ATP-binding protein |
| M. marinum M | MMAR_2279 | - | 0.0 | 91.70% (542) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_3306 | - | 0.0 | 91.01% (545) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3140 | - | 0.0 | 88.38% (542) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_3270 | - | 0.0 | 86.42% (545) | PUTATIVE ABC transporter-related protein |
| M. ulcerans Agy99 | MUL_1481 | - | 0.0 | 91.33% (542) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_2742 | - | 0.0 | 86.90% (542) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3668|M.gilvum_PYR-GCK ---------------------MITATDLEVRAGARTLLSV-EGAALRVQP
Mvan_2742|M.vanbaalenii_PYR-1 MPTPAWVPVQPCHAYLTRSISVITATDLEVRAGARTLLSI-EGSALRVQP
MSMEG_3140|M.smegmatis_MC2_155 ---------------------MITATDLEVRAGARTLLLI-EGSALRVQP
TH_3270|M.thermoresistible__bu ---------------------VITASGLEVRAGARTLLSLDDGQVLRVQP
Rv1473|M.tuberculosis_H37Rv ---------------------MITATDLEVRAGARILLAP-DGPDLRVQP
Mb1508|M.bovis_AF2122/97 ---------------------MITATDLEVRAGARILLAP-DGPDLRVQP
MMAR_2279|M.marinum_M ---------------------MITATDLEVRAGARILLSP-DGPDLRVQP
MUL_1481|M.ulcerans_Agy99 ---------------------MITATDVEVRAGARILLSP-DGPDLRVQP
MAV_3306|M.avium_104 ---------------------MITATDLEVRAGARILLSP-DGPDLRVQP
MLBr_01816|M.leprae_Br4923 ---------------------MITATDLEVRAGARILLSS-DGPDLRVQP
MAB_2736c|M.abscessus_ATCC_199 ---------------------MITATDLEVRAGARTLVYA-PGPALRIQP
:***:.:******* *: * **:**
Mflv_3668|M.gilvum_PYR-GCK GDRIGLVGRNGAGKTTTMRILAGEGEPYAGSVTRTGEIGYLPQDPKEGDL
Mvan_2742|M.vanbaalenii_PYR-1 GDRIGLVGRNGAGKTTTMRILAGEGEPYAGSVTRTGEIGYLPQDPKEGDL
MSMEG_3140|M.smegmatis_MC2_155 GDRIGLVGRNGAGKTTTMRILAGEGEPYAGSVTRSGDIGYLPQDPKEGDL
TH_3270|M.thermoresistible__bu GDRIGLVGRNGAGKTTTLRILAGEGEPYAGTVTRTGDIGYLPQDPKQGDL
Rv1473|M.tuberculosis_H37Rv GDRIGLVGRNGAGKTTTLRILAGEVEPYAGSVTRAGEIGYLPQDPKVGDL
Mb1508|M.bovis_AF2122/97 GDRIGLVGRNGAGKTTTLRILAGEVEPYAGSVTRAGEIGYLPQDPKVGDL
MMAR_2279|M.marinum_M GDRIGLVGRNGAGKTTTLRILAGESEPYAGSVTRAGEIGYLPQDPKEGDL
MUL_1481|M.ulcerans_Agy99 GDRIGLVGRNGAGKTTTLRILAGESEPYAGSVTRAGEIGYLPQDPKEGDL
MAV_3306|M.avium_104 GDRIGLVGRNGAGKTTTLRILAGETEPYAGTIARSGEIGYLPQDPKEGDL
MLBr_01816|M.leprae_Br4923 GDRIGLVGRNGAGKTTTLRILAGATEPYAGSVTWTGEIGYLPQDPKVGNL
MAB_2736c|M.abscessus_ATCC_199 GDRIGLVGRNGAGKTTSMRILAGEGEPYAGSVSRIGEIGYLPQDPKEGNL
****************::***** *****::: *:********* *:*
Mflv_3668|M.gilvum_PYR-GCK DMLARDRVLSARGLDTLLSDLEKQQALMAEVADDAARDKAVRRYGQLEER
Mvan_2742|M.vanbaalenii_PYR-1 DMLARDRVLSARGLDTLLSDLEKQQALMAEVADDAARDKAVRRYGQLEER
MSMEG_3140|M.smegmatis_MC2_155 DVLARDRVLSARGLDTLLADLEKQQALMAEVADDAARDKAVRRYGQLEER
TH_3270|M.thermoresistible__bu DVLARDRVLSARGLDTLLAELEKQQVLMAEVVDDAARDRAVRRYGQLEER
Rv1473|M.tuberculosis_H37Rv DVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDRAIRRYGQLEER
Mb1508|M.bovis_AF2122/97 DVLARDRVLSARGLDVLLTDLEKQQALMAEVADEDERDRAIRRYGQLEER
MMAR_2279|M.marinum_M EVLARDRVLSARGLDVLLTDLEKQQALMAEVADDAARDRAIRRYGQLEER
MUL_1481|M.ulcerans_Agy99 EVLARDRVLSARGLDVLLTDLEKQQALMAEVADDAARDRAIRRYGQLEER
MAV_3306|M.avium_104 DVLARDRVLSARGLDVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEER
MLBr_01816|M.leprae_Br4923 DVLARDRVLSARGLDVLLTDLEKQQALMAEVADDDARDRAIRRYGQLEER
MAB_2736c|M.abscessus_ATCC_199 DLLARDRVLSARGLDTIISEMEKQQTLMAELADDDQRDKAVRRYGQLEER
::*************.:::::****.****:.*: **:*:*********
Mflv_3668|M.gilvum_PYR-GCK FAALGGYAAESEAGRICASLGLPDRVLTQPLRTLSGGQRRRVELARILFA
Mvan_2742|M.vanbaalenii_PYR-1 FAALGGYAAESEAGRICASLGLPDRVLTQPLRTLSGGQRRRVELARILFA
MSMEG_3140|M.smegmatis_MC2_155 FSALGGYAAESEAGRICASLGLPERVLTQPLHTLSGGQRRRVELARILFA
TH_3270|M.thermoresistible__bu FAALGGYAAESEAGRICASLGLPDRVLTQPLRTLSGGQRRRVELARILFA
Rv1473|M.tuberculosis_H37Rv FVALGGYGAESEAGRICASLGLPERVLTQRLRTLSGGQRRRVELARILFA
Mb1508|M.bovis_AF2122/97 FVALGGYGAESEAGRICASLGLPERVLTQRLRTLSGGQRRRVELARILFA
MMAR_2279|M.marinum_M FVALGGYGAESEASRICASLGLPERVLTQQLRTLSGGQRRRVELARILFA
MUL_1481|M.ulcerans_Agy99 FVTLGGYGAESEASRICASLGLPERVLTQQLRTLSGGQRRRVELARILFA
MAV_3306|M.avium_104 FVALGGYGAESEASRICASLGLPERVLTQQLRTLSGGQRRRVELARILFA
MLBr_01816|M.leprae_Br4923 FLALGGYSAESEAGRICASLGLPERVLVQQLCTLSGGQRRRVELARILFA
MAB_2736c|M.abscessus_ATCC_199 FSSLGGYVAESEAARICSSLGLPERILVQPLRTLSGGQRRRVELARILFG
* :**** *****.***:*****:*:*.* * *****************.
Mflv_3668|M.gilvum_PYR-GCK ASEG-GGG--DATTLLLDEPTNHLDADSIGWLRAFLQNHNGGLVVISHDV
Mvan_2742|M.vanbaalenii_PYR-1 ASEA-GSG--SATTLLLDEPTNHLDADSIGWLRTFLQNHTGGLVVISHDV
MSMEG_3140|M.smegmatis_MC2_155 ASET-GSG--SATTLLLDEPTNHLDADSIGWLRDFLKNHTGGLVMISHNV
TH_3270|M.thermoresistible__bu AADS-GSGGGAGTTLLLDEPTNHLDADSIGWLRTFLQNHTGGLVIISHNV
Rv1473|M.tuberculosis_H37Rv ASE---SGAGNSTTLLLDEPTNHLDADSLGWLRDFLRLHTGGLVVISHNV
Mb1508|M.bovis_AF2122/97 ASE---SGAGNSTTLLLDEPTNHLDADSLGWLRDFLRLHTGGLVVISHNV
MMAR_2279|M.marinum_M ASD---TGAGSSTVLLLDEPTNHLDADSVGWLRDFLRAHTGGLIIISHNV
MUL_1481|M.ulcerans_Agy99 ASD---TGAGSSTVLLLDEPTNHLDADSVGWLRDFLRAHTGGLIIISHNV
MAV_3306|M.avium_104 AAEGGATGSGSATTLLLDEPTNHLDADSIGWLRDFLRAHTGGLVIISHNV
MLBr_01816|M.leprae_Br4923 ASRAGTGASGSGTTLLLDEPTNHLDADSLGWLRDFLRSHTGGLVVISHNV
MAB_2736c|M.abscessus_ATCC_199 ASE---GGAGSSMTLLLDEPTNHLDADSIGWLRSFLQNHDGGLVVISHNV
*: . . .**************:**** **: * ***::***:*
Mflv_3668|M.gilvum_PYR-GCK ELLADVVNRVWFLDAVRGEADVYNMGWQKYLDARATDEQRRRRERANAEK
Mvan_2742|M.vanbaalenii_PYR-1 DLLADVVNRVWFLDAVRGEADVYNMGWQKYLDARATDEQRRRRERANAEK
MSMEG_3140|M.smegmatis_MC2_155 ELLEEVVNRVWFLDAVRGEVDVYNMGWQKYLDARATDEQRRRRERANAEK
TH_3270|M.thermoresistible__bu ELLAEVVNRVWFLDAVRGEVDIYNMGWHKYLDARATDEQRRRRERANAER
Rv1473|M.tuberculosis_H37Rv DLVADVVNKVWFLDAVRGQVDVYNMGWQRYVDARATDEQRRIRERANAER
Mb1508|M.bovis_AF2122/97 DLVADVVNKVWFLDAVRGQVDVYNMGWQRYVDARATDEQRRIRERANAER
MMAR_2279|M.marinum_M ELLADVVNRVWFLDAVRGEVDVYNMGWHKYLDARATDEQRRRRERANAER
MUL_1481|M.ulcerans_Agy99 ELLADVVNRVWFLDAVRGEVDVYNMGWHKYLDARATDEQRRRRERANAER
MAV_3306|M.avium_104 ELLADVVNRVWFLDAVRGEVDVYNMSWQKYLDARATDEQRRRRERANAER
MLBr_01816|M.leprae_Br4923 ELIAAVVNRVWFLDAVLGKVDVYNMGWYKYLDSRATDEQRRRRERVNAER
MAB_2736c|M.abscessus_ATCC_199 ELLADVVNKVWFLDAVRGEVDVYNMGWQKYLDARSLDEQRRRRERANAEK
:*: ***:******* *:.*:***.* :*:*:*: ***** ***.***:
Mflv_3668|M.gilvum_PYR-GCK KAGALRAQAAKMGAKATKAVAAQNMLRRAERMMAELDAERVADKVARIKF
Mvan_2742|M.vanbaalenii_PYR-1 KASALRAQAAKMGAKATKAVAAQNMLKRAERMMAALDDERVADKVARIKF
MSMEG_3140|M.smegmatis_MC2_155 KAGALRAQAAKMGAKATKAVAAQNMLRRAERMMAALDEERVADKVARIKF
TH_3270|M.thermoresistible__bu KAAALRAQAAKMGAKATKAVAAQNMLRRAERMLAALDDAPVADKVARIKF
Rv1473|M.tuberculosis_H37Rv KAAALRAQAAKLGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKF
Mb1508|M.bovis_AF2122/97 KAAALRAQAAKLGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKF
MMAR_2279|M.marinum_M KATALRTQAAKMGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKF
MUL_1481|M.ulcerans_Agy99 KATALRTQAAKMGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKF
MAV_3306|M.avium_104 KAAALRTQAAKLGAKATKAVAAQNMLRRADRMMAALDEERVADKVARIKF
MLBr_01816|M.leprae_Br4923 KATALRTQAAKMGAKATKAVAAQNMLRRADRMMAALDEERVIEKVAQIKF
MAB_2736c|M.abscessus_ATCC_199 KASALRTQAAKMGAKATKAVAAQNMLRRAEKMLSGLDEERVADKVARIKF
** ***:****:**************:**::*:: ** * :***:***
Mflv_3668|M.gilvum_PYR-GCK PTPAPCGKTPLIAKGLTKTYGSLEIFTGLDLAIDRGSRVVVLGLNGAGKT
Mvan_2742|M.vanbaalenii_PYR-1 PTPAPCGKTPLTAKGLTKTYGSLEIFSGLDLAIDRGSRVVVLGLNGAGKT
MSMEG_3140|M.smegmatis_MC2_155 PTPAPCGRTPLVAKGLTKNYGSLEVFTGVDLAIDRGSRVVVLGLNGAGKT
TH_3270|M.thermoresistible__bu PTPAPCGRTPLVAKGLTKTYGSLEVFTGVDLAIDRGSRVVVLGLNGAGKT
Rv1473|M.tuberculosis_H37Rv PTPAACGRTPLVANGLGKTYGSLEVFTGVDLAIDRGSRVVILGLNGAGKT
Mb1508|M.bovis_AF2122/97 PTPAACGRTPLVANGLGKTYGSLEVFTGVDLAIDRGSRVVILGLNGAGKT
MMAR_2279|M.marinum_M PTPAACGRVPLVVKGLSKTYGSLEVFTGVDLAIDRGSRVVVLGLNGAGKT
MUL_1481|M.ulcerans_Agy99 PTPAACGRVPLVVKGLSKTYGSLEVFTGVDLAIDRGSRVVVLGLNGAGKT
MAV_3306|M.avium_104 PTPAACGRTPLTATGLSKSYGSLEVFSGVDLAIDRGSRVVVLGLNGAGKT
MLBr_01816|M.leprae_Br4923 PTPAACGRTPLVAKGLSKTYGSLEVFTGVNLAIDRGSRVVVLGLNGAGKT
MAB_2736c|M.abscessus_ATCC_199 PTPAACGRVPLVAKGLTKNYGSLEIFTGVDLAIDRGSRVVVLGLNGAGKT
****.**:.** ..** *.*****:*:*::**********:*********
Mflv_3668|M.gilvum_PYR-GCK TLLRLLAGVEIADAGGLEPGHGLKIGYFAQEHDTLDTMRTVWENIRSAAP
Mvan_2742|M.vanbaalenii_PYR-1 TLLRLLAGVEKADAGEIEPGHGLKIGYFAQEHDTLDNMASVWENIRHAAP
MSMEG_3140|M.smegmatis_MC2_155 TLLRLIAGTEKPDAGHLEPGHGLKIGYFAQEHDTLDNQATVWENIRHAAP
TH_3270|M.thermoresistible__bu TLLRLLAGVETPDAGQIEPGHGLKIGYFAQEHDTLDDHATVWENIRHAAP
Rv1473|M.tuberculosis_H37Rv TLLRLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENVRHAAP
Mb1508|M.bovis_AF2122/97 TLLRLLAGVEQPDTGVLEPGYGLRIGYFAQEHDTLDNDATVWENVRHAAP
MMAR_2279|M.marinum_M TLLRLLAGVEHPDTGGLEPGHGLRIGYFAQEHDTLDNDATVWENIRHAAP
MUL_1481|M.ulcerans_Agy99 TLLRLLAGVEHPDTGGLEPGHGLRIGYFAQEHDTLDNDATVWENIRHAAP
MAV_3306|M.avium_104 TLLRLLAGAETPDTGRIEPGHGLRIGYFAQEHDTLDNDATVWQNIRHAAP
MLBr_01816|M.leprae_Br4923 TLLRVLAGAEKPDVGRLEPGHGLRIGYFAQEHDTLDNEDTVWQNIRHTAP
MAB_2736c|M.abscessus_ATCC_199 TLLRLLAGVETADAGELEPGHGLKLGYFAQEHDTLDDHATVWENIRHAAP
****::**.* .*.* :***:**::*********** :**:*:* :**
Mflv_3668|M.gilvum_PYR-GCK DTGEQDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTANVLL
Mvan_2742|M.vanbaalenii_PYR-1 DTGEQDLRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTANVLL
MSMEG_3140|M.smegmatis_MC2_155 DTGEQDLRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTANVLL
TH_3270|M.thermoresistible__bu DSGEQDLRGLLGAFMFSGPQLEQPAGTLSGGEKTRLALAGLVASAANVLL
Rv1473|M.tuberculosis_H37Rv DAGEQDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTANVLL
Mb1508|M.bovis_AF2122/97 DAGEQDLRGLLGAFMFTGPQLEQPAGTLSGGEKTRLALAGLVASTANVLL
MMAR_2279|M.marinum_M ESGEQELRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTANVLL
MUL_1481|M.ulcerans_Agy99 ESGEQELRGLLGAFMFTGPQLDQPAGTLSGGEKTRLALAGLVASTANVLL
MAV_3306|M.avium_104 DSGEQDLRGLLGAFMFSGPQLDQPAGTLSGGEKTRLALAGLVASTANVLL
MLBr_01816|M.leprae_Br4923 EFGEQDLRGLLGAFMFSGPQLDQLAGTLSGGEKTRLALAGLVASTANVLL
MAB_2736c|M.abscessus_ATCC_199 DTGEQELRGILGAFMFSGPQLEQLAGTLSGGEKTRLALAGLVASTANVLL
: ***:***:******:****:* ********************:*****
Mflv_3668|M.gilvum_PYR-GCK LDEPTNNLDPASREQVLDALRSYAGAVVLVTHDPGAAEALDPQRVLLLPD
Mvan_2742|M.vanbaalenii_PYR-1 LDEPTNNLDPASREQVLDALRSYVGSVVLVTHDPGAAEALDPQRVLLLPD
MSMEG_3140|M.smegmatis_MC2_155 LDEPTNNLDPASREQVLDALRSYEGAVVLVTHDPGAAEALDPQRVVLLPD
TH_3270|M.thermoresistible__bu LDEPTNNLDPASREQVLDALRSYVGAVVLVTHDPGAAEALDPQRVVLLPD
Rv1473|M.tuberculosis_H37Rv LDEPTNNLDPASREQVLDALRSYRGAVVLVTHDPGAAAALGPQRVVLLPD
Mb1508|M.bovis_AF2122/97 LDEPTNNLDPASREQVLDALRSYRGAVVLVTHDPGAAAALGPQRVVLLPD
MMAR_2279|M.marinum_M LDEPTNNLDPASREQVLDALRSYQGAVVLVTHDPGAAEALDPQRVVLLPD
MUL_1481|M.ulcerans_Agy99 LDEPTNNLDPASREQVLDALRSYQGAVVLVTHDPGAAEALDPQRVVLLPD
MAV_3306|M.avium_104 LDEPTNNLDPASREQVLDALRSYTGAVVLVTHDPGAAEALDPQRVVLLPD
MLBr_01816|M.leprae_Br4923 LDEPTNNLDPASRKQVLDALRNYQGAVVLVTHDPGAAKALDPQRVVLLPD
MAB_2736c|M.abscessus_ATCC_199 LDEPTNNLDPASREQVLDALRSYLGAVVLVTHDPGAAEALNPQRVVLLPD
*************:*******.* *:*********** **.****:****
Mflv_3668|M.gilvum_PYR-GCK GTEDFWSDDYRDLIELA
Mvan_2742|M.vanbaalenii_PYR-1 GTEDFWSDEYRDLIELA
MSMEG_3140|M.smegmatis_MC2_155 GTEDFWSDEYRDLIELA
TH_3270|M.thermoresistible__bu GTEDFWSDEYRDLIELA
Rv1473|M.tuberculosis_H37Rv GTEDYWSDEYRDLIELA
Mb1508|M.bovis_AF2122/97 GTEDYWSDEYRDLIELA
MMAR_2279|M.marinum_M ATEDYWSDEYRDLIELA
MUL_1481|M.ulcerans_Agy99 ATEDYWSDEYRDLIELA
MAV_3306|M.avium_104 GTEDYWSDEYRDLIELA
MLBr_01816|M.leprae_Br4923 GTEDYWSDEYRDLIELA
MAB_2736c|M.abscessus_ATCC_199 GTEDYWSDEYRDLIELA
.***:***:********