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M. leprae Br4923 MLBr_01248 (-)

annotation: putative ABC transporter ATP-binding protein
coordinates: 1489194 - 1490864
length: 556

MAEFIYTMKKVRKAHGDKVILDDVTLNFFPGAKIGVVGPNGAGKSSVLRIMAGMDKPNNGDAFLATGASV
GILQQEPPLNEEKTVRGNVEEGLGDIKIKLDRFSEVAELMATDSSSELMEEMGRLQEELDHADAWDLDSQ
LEQAMDVLRCPPPDEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQHLAGYAGAVL
AVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAERLTTQGRKDAKLQKRLTDELAWVRSGAKAR
QAKSKARLQRYEEMAAEAEKNRKFDFEEIQIPVGPRLGNMVVEVEHLDKGYGGRTLIKDLSFTLPRNGIV
GIIGPNGVGKTTLFKTIVGLEQPDGGAVKIGETVKLSYVDQTRAGIDPKKIVWEVVSDGLDHIQVGQTEV
SSRAYVSAFGFKGPDQQKLAGVLSGGERNRLNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPG
CAVVISHDRWFLDRTCTHILAWEGDDEGKWFWFEGNFGAYEENKVERLGAEAARPHRVTHRKLTRD
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01248--100% (556)putative ABC transporter ATP-binding protein
M. leprae Br4923MLBr_01816-3e-5830.43% (506) ABC transporter ATP-binding protein, possibly in EF-3 subfamily
M. leprae Br4923MLBr_01122-4e-1622.87% (411) putative ABC transport protein, ATP-binding component

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2504c-0.092.28% (557) putative ABC transporter ATP-binding protein
M. gilvum PYR-GCKMflv_2568-0.087.63% (558) putative ABC transporter ATP-binding protein
M. tuberculosis H37RvRv2477c-0.092.28% (557) putative ABC transporter ATP-binding protein
M. abscessus ATCC 19977MAB_1560-0.087.63% (558) putative ABC transporter ATP-binding protein
M. marinum MMMAR_3830-0.092.11% (558) ATP-binding component of an ABC transporter
M. avium 104MAV_1695-0.093.01% (558) putative ABC transporter ATP-binding protein
M. smegmatis MC2 155MSMEG_4700-0.087.46% (558) putative ABC transporter ATP-binding protein
M. thermoresistible (build 8)TH_1035-0.088.89% (558) PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC
M. ulcerans Agy99MUL_3757-0.091.58% (558) putative ABC transporter ATP-binding protein
M. vanbaalenii PYR-1Mvan_4070-0.088.51% (557) putative ABC transporter ATP-binding protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb2504c|M.bovis_AF2122/97           MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
Rv2477c|M.tuberculosis_H37Rv        MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MLBr_01248|M.leprae_Br4923          MAEFIYTMKKVRKAHGDKVILDDVTLNFFPGAKIGVVGPNGAGKSSVLRI
MMAR_3830|M.marinum_M               MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MUL_3757|M.ulcerans_Agy99           MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
MAV_1695|M.avium_104                MAEFIYTMKKVRKAHGDKVILDDVTLSFYPGAKIGVVGPNGAGKSSVLRI
TH_1035|M.thermoresistible__bu      MAEFIYTMRKVRKAHGDKVILDDVSLNFLPGAKIGVVGPNGAGKSSVLRI
Mflv_2568|M.gilvum_PYR-GCK          MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
Mvan_4070|M.vanbaalenii_PYR-1       MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
MSMEG_4700|M.smegmatis_MC2_155      MAEFIYTMRKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLRI
MAB_1560|M.abscessus_ATCC_1997      MAEYIYTMMKVRKAHGDKVILDDVTLNFLPGAKIGVVGPNGAGKSSVLKI
                                    ***:**** ***************:*.* *******************:*

Mb2504c|M.bovis_AF2122/97           MAGLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKL
Rv2477c|M.tuberculosis_H37Rv        MAGLDKPNNGDAFLATGATVGILQQEPPLNEDKTVRGNVEEGMGDIKIKL
MLBr_01248|M.leprae_Br4923          MAGMDKPNNGDAFLATGASVGILQQEPPLNEEKTVRGNVEEGLGDIKIKL
MMAR_3830|M.marinum_M               MAGLDKPNNGDAFLATGATVGILLQEPPLNEEKTVRGNVEEGLGDIKVKL
MUL_3757|M.ulcerans_Agy99           IAGLDKPNNGDAFLATGATVGILLQEPPLNEEKTVRGNVEEGLGDIKVKL
MAV_1695|M.avium_104                MAGLDKPNNGEAFLATDATVGILQQEPPLNEEKTVRGNVEEGLGEIKVKL
TH_1035|M.thermoresistible__bu      MAGLDQPNNGEAFLQPGATVGILLQEPPLNEEKTVRGNVEEGLGEIKVKL
Mflv_2568|M.gilvum_PYR-GCK          MAGLDQPNNGDAFLQPGATVGILMQEPQLDETKTVRENVEDGV-AIKGKL
Mvan_4070|M.vanbaalenii_PYR-1       MAGLDQPNNGDAFLAPGATVGILLQEPELDETKTVRENVEEGV-AIKAKL
MSMEG_4700|M.smegmatis_MC2_155      MAGLDQPNNGDAFLAPDATVGILMQEPQLDETKTVRENVEDGV-AIKGKL
MAB_1560|M.abscessus_ATCC_1997      MAGLDKPNNGEAFLANGASVGILQQEPPLDETKTVRENVEDGV-AVKAKL
                                    :**:*:****:***  .*:**** *** *:* **** ***:*:  :* **

Mb2504c|M.bovis_AF2122/97           DRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRC
Rv2477c|M.tuberculosis_H37Rv        DRFNEVAELMATDYTDELMEEMGRLQEELDHADAWDLDAQLEQAMDALRC
MLBr_01248|M.leprae_Br4923          DRFSEVAELMATDSSSELMEEMGRLQEELDHADAWDLDSQLEQAMDVLRC
MMAR_3830|M.marinum_M               DRFNEVAELMATDYSDELMEEMGRLQEDLDHADAWDIDSQLEQAMDALRC
MUL_3757|M.ulcerans_Agy99           DRFNEVAELMATDYSDELMEEMGRLQEDLDHADAWDIDSQLEQAMDALRC
MAV_1695|M.avium_104                DRFNEVAELMATDYSDELMEEMGRLQEELDHADAWDLDSQLEQAMDALRC
TH_1035|M.thermoresistible__bu      DRFNEVAELMATDYSDELMEEMGRLQEELDHADAWDLDSQLEQAMDALRC
Mflv_2568|M.gilvum_PYR-GCK          NRYNEVAELMATDYTDELMDEMGKLQEELDAADAWDIDSQLEQAMDALRC
Mvan_4070|M.vanbaalenii_PYR-1       NRYNEVAELMATDYTDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
MSMEG_4700|M.smegmatis_MC2_155      NRYNEVAELMATDYSDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
MAB_1560|M.abscessus_ATCC_1997      NRYNEVAELMATDYSDELMEEMGKLQEELDAADAWDIDSQLEQAMDALRC
                                    :*:.********* :.***:***:***:** *****:*:*******.***

Mb2504c|M.bovis_AF2122/97           PPADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
Rv2477c|M.tuberculosis_H37Rv        PPADEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MLBr_01248|M.leprae_Br4923          PPPDEPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MMAR_3830|M.marinum_M               PPPEEPVANLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MUL_3757|M.ulcerans_Agy99           PPPEEPVANLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
MAV_1695|M.avium_104                PPPDDPVTNLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVQWLEQ
TH_1035|M.thermoresistible__bu      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
Mflv_2568|M.gilvum_PYR-GCK          PPPDEPVTHLSGGEKRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
Mvan_4070|M.vanbaalenii_PYR-1       PPPDEPVTHLSGGEKRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
MSMEG_4700|M.smegmatis_MC2_155      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
MAB_1560|M.abscessus_ATCC_1997      PPPDEPVTHLSGGERRRVALCKLLLSKPDLLLLDEPTNHLDAESVLWLEQ
                                    **.::**::*****:****************************** ****

Mb2504c|M.bovis_AF2122/97           HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Rv2477c|M.tuberculosis_H37Rv        HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
MLBr_01248|M.leprae_Br4923          HLAGYAGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
MMAR_3830|M.marinum_M               HLASYAGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAD
MUL_3757|M.ulcerans_Agy99           HLASYAGAVLAVTHDRYFLDNVAEWILELDRGRTYPYEGNYSTYLEKKAD
MAV_1695|M.avium_104                HLAAYAGAVLAVTHDRYFLDNVAQWILELDRGRAYPYEGNYSTYLEKKAD
TH_1035|M.thermoresistible__bu      HLAEYKGAVLAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Mflv_2568|M.gilvum_PYR-GCK          HLAEYKGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
Mvan_4070|M.vanbaalenii_PYR-1       HLAEYKGAVLAVTHDRYFLDNVAEWILELDRGRAFPYEGNYSTYLEKKAE
MSMEG_4700|M.smegmatis_MC2_155      HLASYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
MAB_1560|M.abscessus_ATCC_1997      HLATYPGAILAVTHDRYFLDNVAEWILELDRGRAYPYEGNYSTYLEKKAE
                                    *** * **:**************:*********::**************:

Mb2504c|M.bovis_AF2122/97           RLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
Rv2477c|M.tuberculosis_H37Rv        RLAVQGRKDAKLQKRLTEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
MLBr_01248|M.leprae_Br4923          RLTTQGRKDAKLQKRLTDELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
MMAR_3830|M.marinum_M               RLAVQGRKDAKLQKRLQEELAWVRSGAKARQAKSKARLQRYEEMVAEAEK
MUL_3757|M.ulcerans_Agy99           RLAVQGRKDAKLQKRLQEELAWVRSGAKARQAKSKARLQRYEEMVAEAEK
MAV_1695|M.avium_104                RLAVQGRKDAKLQKRLSEELAWVRSGAKARQAKSKARLQRYEEMAAEAEK
TH_1035|M.thermoresistible__bu      RLEVQGRKDAKLHKRLKEELAWVRSGTKARQAKGKARLQRYEEMAAEAEK
Mflv_2568|M.gilvum_PYR-GCK          RIAVTGRKDAKLQKRLKDELEWVRSGAKARQAKNKARLQRYEEMAAEAEK
Mvan_4070|M.vanbaalenii_PYR-1       RIAVQGRKDAKLQKRLKDELDWVRSGAKARQAKSKARLQRYEEMAAEAEK
MSMEG_4700|M.smegmatis_MC2_155      RLEVQGKKDQKLQKRLKEELAWVRSGAKARQAKNKARLDRYEEMVAEAEK
MAB_1560|M.abscessus_ATCC_1997      RIAVQGRKDAKLHKRLQEELAWVRSGAKARQAKNKARLQRYEEMVTEAEK
                                    *: . *:** **:*** :** *****:******.****:*****.:****

Mb2504c|M.bovis_AF2122/97           TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIV
Rv2477c|M.tuberculosis_H37Rv        TRKLDFEEIQIPVGPRLGNVVVEVDHLDKGYDGRALIKDLSFSLPRNGIV
MLBr_01248|M.leprae_Br4923          NRKFDFEEIQIPVGPRLGNMVVEVEHLDKGYGGRTLIKDLSFTLPRNGIV
MMAR_3830|M.marinum_M               TRKLDFEEIQIPVGPRLGSVVVEVEHLDKGFGGRTLIKDLSFTLPRNGIV
MUL_3757|M.ulcerans_Agy99           TRKLDFEEIQIPVGPRLGSVVVEVEHLDKGFGGRTLIKDLSFTLPRNGTV
MAV_1695|M.avium_104                TRKLDFEEIQIPVGPRLGNVVVEVEHLDKGYDGRTLIKDLSFTLPRNGIV
TH_1035|M.thermoresistible__bu      SRKLDFEEIQIPTPPRLGNVVVEVKNLDKGYDGRPLIKDLSFTLPRNGIV
Mflv_2568|M.gilvum_PYR-GCK          TRKLDFEEIQIPVGPRLGNVVVEVEHLDKGFDGRLLIKDLSFTLPRNGIV
Mvan_4070|M.vanbaalenii_PYR-1       TRKLDFEEIQIPTGPRLGNVVVEVEHLDKGFGGRQLIKDLSFTLPRNGIV
MSMEG_4700|M.smegmatis_MC2_155      TRKLDFEEIQIPTPPRLGSVVVEVEHLDKGFNGRTLIKDLSFTLPRNGIV
MAB_1560|M.abscessus_ATCC_1997      TRKLDFEEIQIPTGPRLGNVVVEVEHLDKGFEGRALIKDLSFTLPRNGIV
                                    .**:********. ****.:****.:****: ** *******:***** *

Mb2504c|M.bovis_AF2122/97           GVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
Rv2477c|M.tuberculosis_H37Rv        GVIGPNGVGKTTLFKTIVGLETPDSGSVKVGETVKLSYVDQARAGIDPRK
MLBr_01248|M.leprae_Br4923          GIIGPNGVGKTTLFKTIVGLEQPDGGAVKIGETVKLSYVDQTRAGIDPKK
MMAR_3830|M.marinum_M               GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRAGIDPKK
MUL_3757|M.ulcerans_Agy99           GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRAGIDPKK
MAV_1695|M.avium_104                GVIGPNGVGKTTLFKTIVGLEQPDSGTVKVGETVKLSYVDQARAGIDPKK
TH_1035|M.thermoresistible__bu      GVIGPNGVGKTTLFKTIVGLEEPDSGTVKIGETVKLSYVDQTRAGIDPNK
Mflv_2568|M.gilvum_PYR-GCK          GVIGPNGVGKTTLFKTIVGLEEPDSGTVKVGETVKLSYVDQTRGGIDPKK
Mvan_4070|M.vanbaalenii_PYR-1       GVIGPNGVGKTTLFKTIVGLEQPDSGTVKIGETVKLSYVDQSRAGIDPKK
MSMEG_4700|M.smegmatis_MC2_155      GVIGPNGVGKTTLFKTIVGLEQPDSGTVKIGETVKLSYVDQTRAGIDPKK
MAB_1560|M.abscessus_ATCC_1997      GVIGPNGVGKTTLFKTIVGLENPDGGEVKVGETVKLSYVDQSRAGIDPKK
                                    *:******************* **.* **:***********:*.****.*

Mb2504c|M.bovis_AF2122/97           TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Rv2477c|M.tuberculosis_H37Rv        TVWEVVSDGLDYIQVGQTEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MLBr_01248|M.leprae_Br4923          IVWEVVSDGLDHIQVGQTEVSSRAYVSAFGFKGPDQQKLAGVLSGGERNR
MMAR_3830|M.marinum_M               TVWEVVSDGLDYIEVGQSEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MUL_3757|M.ulcerans_Agy99           TVWEVVSDGLDSIEVGQSEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MAV_1695|M.avium_104                TVWEVVSDGLDYIEVGQNEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
TH_1035|M.thermoresistible__bu      TVWEVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Mflv_2568|M.gilvum_PYR-GCK          TVWEVVSDGLDFIEVGQNEVPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
Mvan_4070|M.vanbaalenii_PYR-1       TVWEVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MSMEG_4700|M.smegmatis_MC2_155      TVWQVVSDGLDYIEVGQNEIPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
MAB_1560|M.abscessus_ATCC_1997      NVWEVVSDGLDHIVVGQNEMPSRAYVSAFGFKGPDQQKPAGVLSGGERNR
                                     **:******* * ***.*:.***************** ***********

Mb2504c|M.bovis_AF2122/97           LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRW
Rv2477c|M.tuberculosis_H37Rv        LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALLNFPGCAVVISHDRW
MLBr_01248|M.leprae_Br4923          LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRW
MMAR_3830|M.marinum_M               LNLALTLKQGGNLILLDEPTNDLDVETLSSLENALVNFPGCAVVISHDRW
MUL_3757|M.ulcerans_Agy99           LNLALTLKQGGNLILLDEPTNDLDVETLSSLENALVNFPGCAVVISHDRW
MAV_1695|M.avium_104                LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALVNFPGCAVVISHDRW
TH_1035|M.thermoresistible__bu      LNLALTLKEGGNLILLDEPTNDLDVETLGSLENALEKFPGCAVVISHDRW
Mflv_2568|M.gilvum_PYR-GCK          LNLALTLKEGGNLILLDEPTNDLDVETLSSLENALQNFPGCAVVISHDRW
Mvan_4070|M.vanbaalenii_PYR-1       LNLALTLKEGGNLLLLDEPTNDLDVETLSSLENALEKFPGCAVVISHDRW
MSMEG_4700|M.smegmatis_MC2_155      LNLALTLKEGGNLILLDEPTNDLDVETLSSLENALQQFPGCAVVISHDRW
MAB_1560|M.abscessus_ATCC_1997      LNLALTLKQGGNLILLDEPTNDLDVETLGSLENALEQFPGCAVVISHDRW
                                    ********:****:**************.****** :*************

Mb2504c|M.bovis_AF2122/97           FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRV
Rv2477c|M.tuberculosis_H37Rv        FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKVERLGVDAARPHRV
MLBr_01248|M.leprae_Br4923          FLDRTCTHILAWEGDD--EGKWFWFEGNFGAYEENKVERLGAEAARPHRV
MMAR_3830|M.marinum_M               FLDRTCTHILAWEGDADSEAKWFWFEGNFGAYEENKVERLGVEAARPHRV
MUL_3757|M.ulcerans_Agy99           FLDRTCTHILAWEGDADSEAKWFWFEGNFGAYEENKVERLGVEAARPHRV
MAV_1695|M.avium_104                FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKIERLGAEAARPHRV
TH_1035|M.thermoresistible__bu      FLDRVCTHILAWEGTEDNPAQWFWFEGNFAAYEENKVARLGPEAARPHRV
Mflv_2568|M.gilvum_PYR-GCK          FLDRTCTHILAWEGDSDNEAKWFWFEGNFGGYEENKIERLGADAARPHRV
Mvan_4070|M.vanbaalenii_PYR-1       FLDRTCTHILAWEGDADNEAKWFWFEGNFGGYEENKIERLGAEAARPHRV
MSMEG_4700|M.smegmatis_MC2_155      FLDRTCTHILAWEGDDDNEAKWFWFEGNFGAYEENKIQRMGAEAARPHRV
MAB_1560|M.abscessus_ATCC_1997      FLDRTCTHILAWEGSDDNPASWFWFEGNFQAYEENKVERLGIDAARPHRV
                                    ****.*********     ..******** .*****: *:* :*******

Mb2504c|M.bovis_AF2122/97           THRKLTRG
Rv2477c|M.tuberculosis_H37Rv        THRKLTRG
MLBr_01248|M.leprae_Br4923          THRKLTRD
MMAR_3830|M.marinum_M               THRRLTRD
MUL_3757|M.ulcerans_Agy99           THRRLTRD
MAV_1695|M.avium_104                THRKLTRD
TH_1035|M.thermoresistible__bu      THRRLTRD
Mflv_2568|M.gilvum_PYR-GCK          THRKLTRD
Mvan_4070|M.vanbaalenii_PYR-1       THRKLTRG
MSMEG_4700|M.smegmatis_MC2_155      THRRLTRD
MAB_1560|M.abscessus_ATCC_1997      THRRLTRD
                                    ***:***.