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INPGRARVVAWALWDCGSAGLNAIVITFVFSVYLTGSVGAGLPGDTTPASWLGRALTVAGIAVAFLAPAT GVWVDAPERRRPALAVLTGCVVVVTASMSLIRDDHSYLWAGLVLLALAGACGELASVPYNAMLRQLSTPD NSGRVSALGLALGYSGIVVLLVLVYFGFIAGDGDTRGLLGLPVADGQNVRAVMLLAAAWLALFAVPVFFA VPSPHVSVPSARTSFIGAYRKLWSEVRSEWERDRNIVYYLLASAVFRDGLAGVFTFGAVLGVSVYGISDA DVLLFGISACVIAAIGAVVGGQLDDRIGSKPIIVGSLAAMITAGVVMMVLSGPVAFWACGLALCLFIGPT QSSARTLMLRMSAEGKEGVAFGLYTTVGRAVSFLAPWLFFMFIDIFGTDRAGMGGLCLVLVAGLVGMAAV RTPERVTAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4721 | - | - | 100% (430) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_2991 | - | 1e-05 | 22.77% (325) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_6711 | - | 2e-05 | 25.00% (180) | 4-hydroxybenzoate transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2536c | - | 1e-156 | 62.82% (433) | hypothetical protein Mb2536c |
| M. gilvum PYR-GCK | Mflv_2546 | - | 1e-171 | 69.60% (421) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2508c | - | 1e-156 | 62.82% (433) | hypothetical protein Rv2508c |
| M. leprae Br4923 | MLBr_00430 | - | 1e-153 | 63.27% (422) | hypothetical protein MLBr_00430 |
| M. abscessus ATCC 19977 | MAB_1538 | - | 1e-121 | 50.71% (420) | hypothetical protein MAB_1538 |
| M. marinum M | MMAR_3855 | - | 1e-160 | 63.81% (431) | integral membrane leucine and alanine rich protein |
| M. avium 104 | MAV_1667 | - | 1e-160 | 65.25% (423) | permease of the major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_1384 | - | 1e-180 | 73.16% (421) | PROBABLE CONSERVED INTEGRAL MEMBRANE LEUCINE AND ALANINE RICH |
| M. ulcerans Agy99 | MUL_3787 | - | 1e-157 | 62.65% (431) | integral membrane leucine and alanine rich protein |
| M. vanbaalenii PYR-1 | Mvan_4097 | - | 1e-173 | 69.83% (421) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4721|M.smegmatis_MC2_155 MINPG---------------------RARVVAWALWDCGSAGLNAIVITF
TH_1384|M.thermoresistible__bu MSQTRRVGRPPS----------QPAQRSQVLAWALWDCGSTGFNAIVITF
Mflv_2546|M.gilvum_PYR-GCK MSQVPSTTGPPT----------DAAPRARVWAWAMWDFGATAVNAIVITF
Mvan_4097|M.vanbaalenii_PYR-1 MSELSPTIGPPVGS--------AGAKRSRVLAWAMWDFGATAINAIVITF
MMAR_3855|M.marinum_M MTNP--ATGTFV--------------RSRVVAWALWDCGSTGLNAIVTTF
MUL_3787|M.ulcerans_Agy99 MTNP--ATGTFV--------------RSRVVAWALWDCGSTGLNAMVTTF
Mb2536c|M.bovis_AF2122/97 MNNPGSRAGTLL--------------HFRVVAWAMWDCGSTGLNAIVTTF
Rv2508c|M.tuberculosis_H37Rv MNNPGSRAGTLL--------------HFRVVAWAMWDCGSTGLNAIVTTF
MLBr_00430|M.leprae_Br4923 MNQPESVAGTMV--------------RSWVVAWAMWDCGSTGLTAIVATF
MAV_1667|M.avium_104 -----------------------------MVAWALWDCGSTGLNAIVATF
MAB_1538|M.abscessus_ATCC_1997 MSMPGVEEPKGRQDPGPGRQLDTPTSRGRIAAWAAFDWGSAAFNTVIVMF
: *** :* *::...::: *
MSMEG_4721|M.smegmatis_MC2_155 VFSVYLTGSVGAGLPGDTTPASWLGRALTVAGIAVAFLAPATGVWVDAPE
TH_1384|M.thermoresistible__bu VFAVYLTGTVGADLPGDTSAAGWLGRAMAAGGLAVAVLAPATGVWVEAPR
Mflv_2546|M.gilvum_PYR-GCK VFTVYLTAVVGDDLPGDTTPASWLGRALAAAGIVVALLAPVTGVWVDAPA
Mvan_4097|M.vanbaalenii_PYR-1 VFTVYLTSTVGDDLPGETSPASWLGRALAVAGLVVALLAPVTGVWVDAPA
MMAR_3855|M.marinum_M VFSVYLTSMVGEGMPGGSDPASWLGRAAAAAGLTIALLAPLVGVWVESPH
MUL_3787|M.ulcerans_Agy99 VFSVYLTSMVGEGMPGGSDPASWLGRAAAAAGLTIALLAPLVGVWVESPH
Mb2536c|M.bovis_AF2122/97 VFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLTIGVLAPVVGVWVESPH
Rv2508c|M.tuberculosis_H37Rv VFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLTIGVLAPVVGVWVESPH
MLBr_00430|M.leprae_Br4923 VFSVYLTSSVGVGMPDGISLVSWLGRAGAVAGLTIAVLAPAIGVWVESPH
MAV_1667|M.avium_104 VFAVYLTSSVGVGIGGSTTPASWLGRAAAIAGLTVALLAPAVGVWVESPH
MAB_1538|M.abscessus_ATCC_1997 IFTPYLTGRVGAGLPDG-VPQGLLGWMMGLGGVLVFLLAPVIGVWADTPQ
:*: ***. ** .: . . ** .*: : .*** ***.::*
MSMEG_4721|M.smegmatis_MC2_155 RRRPALAVLTGCVVVVTASMSLIRDDHSYLWAGLVLLALAGACGELASVP
TH_1384|M.thermoresistible__bu RRRAALGVLTGLTVALTAAMSLIRDDHRYLWPALVLLACAAATSELATVP
Mflv_2546|M.gilvum_PYR-GCK RRRRALTVLTGMVVLLTASLSLIRDDHHYLWPALVLLACTAACSELATVP
Mvan_4097|M.vanbaalenii_PYR-1 RRRRALAILTGLVVMLTASMSLIRDDHRYLWPGLILLACTAACGELSTVP
MMAR_3855|M.marinum_M RRRVALGVLTSVTVVLTCAMFLIHDSPGYLWAGLALLAATAACSDLASVP
MUL_3787|M.ulcerans_Agy99 RRRVALGVLTSVTVALTCAMFLIHDSPGYLWAGLALLAATAACSDLASVP
Mb2536c|M.bovis_AF2122/97 RRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVP
Rv2508c|M.tuberculosis_H37Rv RRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVP
MLBr_00430|M.leprae_Br4923 RRRVTLGVLTVLAVALTCGMSFIRDQPSYLWAGLMLLAGTAACGDLASVP
MAV_1667|M.avium_104 RRRVALSVLTALAVTLTGSMFFIRDRPGYLWAGLVLLGATAACGDLASVP
MAB_1538|M.abscessus_ATCC_1997 RRRVALGTLTTLVVAVATAMSMVREDNRYLWLGLGLYCAGSVFNELAQVP
*** :* ** .* :: .: :::: *** .* * .. .:*: **
MSMEG_4721|M.smegmatis_MC2_155 YNAMLRQLSTPDNSGRVSALGLALGYSGIVVLLVLVYFGFIAGDG----D
TH_1384|M.thermoresistible__bu YNAMLRQLSTPQNSGRVSGFGWAMGYFGSVTLLLVVYAGFIAGEG----D
Mflv_2546|M.gilvum_PYR-GCK YNAMLRELSTPRTSGRISGFGLALGYFGSVLALLVVYLGFISGGG----D
Mvan_4097|M.vanbaalenii_PYR-1 YNAMLRDLSTPQTSGRVSGFGLALGYFGSVLALLVVYVGFIAGAG----D
MMAR_3855|M.marinum_M YNSMLRQLSTPTTASRISGFGWASGYVGSVVLLILIYLGFVAGSG----A
MUL_3787|M.ulcerans_Agy99 YNSMLRQLSTPTTASRISGFGWASGYVGSVVLLILIYLGFVAGSG----A
Mb2536c|M.bovis_AF2122/97 YNAMLRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSG----S
Rv2508c|M.tuberculosis_H37Rv YNAMLRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSG----S
MLBr_00430|M.leprae_Br4923 YNAMLRQLSTPATAGRISGLGWASGYVGSVVLLLLIYLGFISGTG----E
MAV_1667|M.avium_104 YNAMLRQLSTPRTAGRISGFGWAAGYVGSVLLLLVIYTGFIAGSGSGPDA
MAB_1538|M.abscessus_ATCC_1997 YNAMLHGLTTPANASRVSGLGLAAAYIGGVLVLLLCYLGFISGDG----P
**:**: *:** .:.*:*.:* * .* * * *:: * **::* *
MSMEG_4721|M.smegmatis_MC2_155 TRGLLGLPVADGQNVRAVMLLAAAWLALFAVPVFFAVPSPH--VSVPSAR
TH_1384|M.thermoresistible__bu RRGLLGLPVADGLNVRAAMLLTAAWFLLFALPVLITVPSPP--DDGHRAR
Mflv_2546|M.gilvum_PYR-GCK TRGLLALPAADGQNVRAAMLLVAAWFALFALPLLISAPRHT--GPETAPA
Mvan_4097|M.vanbaalenii_PYR-1 TRGLLHLPVADGQNVRAAMLLVAAWFAVFALPLLISPPPVL--AQTPPPR
MMAR_3855|M.marinum_M HRGLLQLPAHDGFNIRVAMLLAAAWLAVLASPLLLVAHRLPDVGTVPQPA
MUL_3787|M.ulcerans_Agy99 HRGLLQLPAHDGFNIRVAMLLAAAWLAVLASPLLLVAHRLPDVGTVPQPA
Mb2536c|M.bovis_AF2122/97 QRGLLQLPVANGLNVRMAMLVAAAWLALLGLPLLLVAHRLPDSGAASHPS
Rv2508c|M.tuberculosis_H37Rv QRGLLQLPVANGLNVRMAMLVAAAWLALLGLPLLLVAHRLPDSGAASHPS
MLBr_00430|M.leprae_Br4923 LRGLLQLPTHDGIYVRAAMLLAAAWLALLALPLLLTAHRLPSLGEVSHPT
MAV_1667|M.avium_104 TRGLLRVPLRDGLYVREAMLVAAAWLALFALPLLFVAHRLTESAEGYRPT
MAB_1538|M.abscessus_ATCC_1997 TRGLFQVPAADGYDVRVSALLAAAWFAVFALPLVLTR-PVPDPAAPPPSS
***: :* :* :* *:.***: ::. *:.: .
MSMEG_4721|M.smegmatis_MC2_155 TSFIGAYRKLWSEVRSEWERDRNIVYYLLASAVFRDGLAGVFTFGAVLGV
TH_1384|M.thermoresistible__bu TGFLGAYRRLAAELAGEWRRDRNVVYYLIASAVFRDGLAGVFAFGAVLGV
Mflv_2546|M.gilvum_PYR-GCK VGFLGAYRRLWQEIGREWRRDRNFVYYLGSSAVFRDGLTGVFTFGAVLGV
Mvan_4097|M.vanbaalenii_PYR-1 VGFIGAYRRLWHDLRAEWRRDRNLVYYLGASAIFRDGLTGVFTFGAVLGV
MMAR_3855|M.marinum_M TRMLGAYRKLWADISSEWRRDRNLVYFLIASAIFRDGLAAMFAFGAVLGV
MUL_3787|M.ulcerans_Agy99 TRMLGAYRKLWADISSEWRRDRNLVYFLIASAIFRDGLAAMFAFGAVLGA
Mb2536c|M.bovis_AF2122/97 TGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVLGV
Rv2508c|M.tuberculosis_H37Rv TGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVLGV
MLBr_00430|M.leprae_Br4923 S-MLGGYRKLWSEVSAEWRRDRNLVYFLVASALFRDGLAATLGFGAVLGV
MAV_1667|M.avium_104 S-MLGGYRKLWTEVREEWRRDRNLVYFLFASALFRDGLAAIFAFGAVLGV
MAB_1538|M.abscessus_ATCC_1997 PGVLGVYRELWRDLVEQWHMDRRIIYFLVASAIFRDGMVAMFALTPVIAN
.:* **.* :: :*. **..:*:* :**:****:.. : : .*:.
MSMEG_4721|M.smegmatis_MC2_155 SVYGISDADVLLFGISACVIAAIGAVVGGQLDDRIGSKPIIVGSLAAMIT
TH_1384|M.thermoresistible__bu TVYGVSEADVLLFGVCASVIAAIGAVLGGLVDDRVGSKPVIIGSLAAMIA
Mflv_2546|M.gilvum_PYR-GCK NVYGVSQADVLLFGVAACVVAALGSVAGGRVDDRVGSKPVIVASLVALIA
Mvan_4097|M.vanbaalenii_PYR-1 QVYGVSSADVLLFGVAACVVAAVGSVIGGRLDDRVGSKHVIVASLVSMIV
MMAR_3855|M.marinum_M NVYGLTQADVLLFGVAASVVAAVGAVVGGFVDHRVGSKPVIVASLASILI
MUL_3787|M.ulcerans_Agy99 NVYGLTQADVLLFGVAASVVAAVGAVVGGFVDHRVGSKPVIVASLASILI
Mb2536c|M.bovis_AF2122/97 NAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIA
Rv2508c|M.tuberculosis_H37Rv NAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIA
MLBr_00430|M.leprae_Br4923 NAYGISQANVLMFGVVASLVAAVGAVLGGFVDHRIGSKRVIVGSLVAIIV
MAV_1667|M.avium_104 NVYGISQADVLVFGVAASVVAAVGAVLGGFVDHRVGSKPVIVASLLAIVV
MAB_1538|M.abscessus_ATCC_1997 GVFHLSGADITLFGVAGNVMAAVGAVVGGLVDTRLGSKGIIVGSLAVIVS
.: :: *:: :** . ::**:*:* ** :* *:*** :*:.** ::
MSMEG_4721|M.smegmatis_MC2_155 AGVVMMVLSGPVAFWACGLALCLFIGPTQSSARTLMLRMSAEGKEGVAFG
TH_1384|M.thermoresistible__bu TGLTLLNLSGAAAFWICGLLLCMFIGPTQSSARTLMLRMATLGKEGVAFG
Mflv_2546|M.gilvum_PYR-GCK VGLTLMVLSGPMAFWACGLLLCLFIGPTLSSARTLMMRMSAHGKEGVTFG
Mvan_4097|M.vanbaalenii_PYR-1 VGLVLMVLSGVLAFWVCGLLLCLFIGPTLSSARTLMLRMCAHGKEGVTFG
MMAR_3855|M.marinum_M SAIVLMVLSGATAFWVCGLLLCLFIGPSQSSARALLLRMAPHGKEGVAFG
MUL_3787|M.ulcerans_Agy99 SAIVLMVLSGATAFWVCGLLLCLFIGPSQSSARALLLRMAPHGKEGVAFG
Mb2536c|M.bovis_AF2122/97 AALTLLTLSGPTAFWACGLLLCVFIGPAQSSARALLLHMAQHGKEGVAFG
Rv2508c|M.tuberculosis_H37Rv AALTLLTLSGPTAFWACGLLLCVFIGPAQSSARALLLHMAQHGKEGVAFG
MLBr_00430|M.leprae_Br4923 TALTLMTLSGPLAFWVCGLVLCLFIGPSQSSSRALLLHMAKHGREGVAFG
MAV_1667|M.avium_104 LGLTLMALSGPVAFWACGLLLCMFIGPSQSSSRALLLQMAKHGREGVAFG
MAB_1538|M.abscessus_ATCC_1997 LGIVMMFLTGQPAFWICGLAIAAFVGPPQSAARTLVLRMAPVGREAFVFG
.:.:: *:* *** *** :. *:**. *::*:*:::*. *:*...**
MSMEG_4721|M.smegmatis_MC2_155 LYTTVGRAVSFLAPWLFFMFIDIFGTDRAGMGGLCLVLVAGLVGMAAVRT
TH_1384|M.thermoresistible__bu LYTTTGRAMSFLSPWMFFTFIDLFGTDRAGMAGLCVVLVAGLVAMLAVRV
Mflv_2546|M.gilvum_PYR-GCK LYTTAGRAATFLAPWLFSVFIDVFDSYRAGMGGLVFVLALGLLLFLPVRV
Mvan_4097|M.vanbaalenii_PYR-1 FYTTAGRAATFLAPWLFSLSIDVFDSPRAGMGGLVAVLVLGLLLFLPVRA
MMAR_3855|M.marinum_M LYTMTGRAVAFLGPWLFSIFVDIFSAVRAGLGGICLVLAVGLVGMLVVRV
MUL_3787|M.ulcerans_Agy99 LYTMTGHAVAFLGPWLFSIFVDIFSAVRAGLGGICLVLAVGLVGMLVVGV
Mb2536c|M.bovis_AF2122/97 LYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVLTTGLLLMLRVQV
Rv2508c|M.tuberculosis_H37Rv LYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVLTTGLLLMLRVQV
MLBr_00430|M.leprae_Br4923 LYTMTGRAASFVAPWSFSIFVDGFGVVRAGLGGISVVLLAGLLGMLMVRV
MAV_1667|M.avium_104 LYTMTGRAVSFVAPWLFSVFVDAFGAVRAGLGGISLVLTAGLLAMLAVRV
MAB_1538|M.abscessus_ATCC_1997 LYTMTGRAVSFVGPWLFATFALLFHATRAGIAGPVLMIGLGMVAVILVKV
:** .*:* :*:.** * * ***:.* :: *:: . * .
MSMEG_4721|M.smegmatis_MC2_155 PERVTAR----------------
TH_1384|M.thermoresistible__bu PRRAG------------------
Mflv_2546|M.gilvum_PYR-GCK PPRHGATVSASARRS--------
Mvan_4097|M.vanbaalenii_PYR-1 PHRRDPV----------------
MMAR_3855|M.marinum_M PRHGGVVVTETT-----------
MUL_3787|M.ulcerans_Agy99 PRHGGVVVTETT-----------
Mb2536c|M.bovis_AF2122/97 SRHGGALTTAQSS----------
Rv2508c|M.tuberculosis_H37Rv SRHGGALTTAQSS----------
MLBr_00430|M.leprae_Br4923 PTRREAAAVGLSWWRSQARRGQV
MAV_1667|M.avium_104 P-RRAPVAVEAA-----------
MAB_1538|M.abscessus_ATCC_1997 PRYDPVRDEIVSGAG--------
.