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MNNPGSRAGTLLHFRVVAWAMWDCGSTGLNAIVTTFVFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLT IGVLAPVVGVWVESPHRRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVPYNAM LRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSGSQRGLLQLPVANGLNVRMAMLVAAAWLAL LGLPLLLVAHRLPDSGAASHPSTGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVL GVNAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIAAALTLLTLSGPTAFWACG LLLCVFIGPAQSSARALLLHMAQHGKEGVAFGLYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVL TTGLLLMLRVQVSRHGGALTTAQSS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2536c | - | - | 100% (445) | hypothetical protein Mb2536c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2546 | - | 1e-160 | 65.12% (430) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv2508c | - | 0.0 | 100.00% (445) | hypothetical protein Rv2508c |
| M. leprae Br4923 | MLBr_00430 | - | 0.0 | 75.74% (441) | hypothetical protein MLBr_00430 |
| M. abscessus ATCC 19977 | MAB_1538 | - | 1e-122 | 49.88% (421) | hypothetical protein MAB_1538 |
| M. marinum M | MMAR_3855 | - | 0.0 | 77.10% (441) | integral membrane leucine and alanine rich protein |
| M. avium 104 | MAV_1667 | - | 0.0 | 77.30% (423) | permease of the major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4721 | - | 1e-156 | 62.82% (433) | permease of the major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_1384 | - | 1e-166 | 66.90% (423) | PROBABLE CONSERVED INTEGRAL MEMBRANE LEUCINE AND ALANINE RICH |
| M. ulcerans Agy99 | MUL_3787 | - | 0.0 | 76.64% (441) | integral membrane leucine and alanine rich protein |
| M. vanbaalenii PYR-1 | Mvan_4097 | - | 1e-153 | 64.03% (417) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2546|M.gilvum_PYR-GCK MSQVPSTTGPPT----------DAAPRARVWAWAMWDFGATAVNAIVITF
Mvan_4097|M.vanbaalenii_PYR-1 MSELSPTIGPPVGS--------AGAKRSRVLAWAMWDFGATAINAIVITF
MSMEG_4721|M.smegmatis_MC2_155 MINPG---------------------RARVVAWALWDCGSAGLNAIVITF
TH_1384|M.thermoresistible__bu MSQTRRVGRPPS----------QPAQRSQVLAWALWDCGSTGFNAIVITF
Mb2536c|M.bovis_AF2122/97 MNNPGSRAGTLL--------------HFRVVAWAMWDCGSTGLNAIVTTF
Rv2508c|M.tuberculosis_H37Rv MNNPGSRAGTLL--------------HFRVVAWAMWDCGSTGLNAIVTTF
MLBr_00430|M.leprae_Br4923 MNQPESVAGTMV--------------RSWVVAWAMWDCGSTGLTAIVATF
MAV_1667|M.avium_104 -----------------------------MVAWALWDCGSTGLNAIVATF
MMAR_3855|M.marinum_M MTNP--ATGTFV--------------RSRVVAWALWDCGSTGLNAIVTTF
MUL_3787|M.ulcerans_Agy99 MTNP--ATGTFV--------------RSRVVAWALWDCGSTGLNAMVTTF
MAB_1538|M.abscessus_ATCC_1997 MSMPGVEEPKGRQDPGPGRQLDTPTSRGRIAAWAAFDWGSAAFNTVIVMF
: *** :* *::...::: *
Mflv_2546|M.gilvum_PYR-GCK VFTVYLTAVVGDDLPGDTTPASWLGRALAAAGIVVALLAPVTGVWVDAPA
Mvan_4097|M.vanbaalenii_PYR-1 VFTVYLTSTVGDDLPGETSPASWLGRALAVAGLVVALLAPVTGVWVDAPA
MSMEG_4721|M.smegmatis_MC2_155 VFSVYLTGSVGAGLPGDTTPASWLGRALTVAGIAVAFLAPATGVWVDAPE
TH_1384|M.thermoresistible__bu VFAVYLTGTVGADLPGDTSAAGWLGRAMAAGGLAVAVLAPATGVWVEAPR
Mb2536c|M.bovis_AF2122/97 VFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLTIGVLAPVVGVWVESPH
Rv2508c|M.tuberculosis_H37Rv VFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLTIGVLAPVVGVWVESPH
MLBr_00430|M.leprae_Br4923 VFSVYLTSSVGVGMPDGISLVSWLGRAGAVAGLTIAVLAPAIGVWVESPH
MAV_1667|M.avium_104 VFAVYLTSSVGVGIGGSTTPASWLGRAAAIAGLTVALLAPAVGVWVESPH
MMAR_3855|M.marinum_M VFSVYLTSMVGEGMPGGSDPASWLGRAAAAAGLTIALLAPLVGVWVESPH
MUL_3787|M.ulcerans_Agy99 VFSVYLTSMVGEGMPGGSDPASWLGRAAAAAGLTIALLAPLVGVWVESPH
MAB_1538|M.abscessus_ATCC_1997 IFTPYLTGRVGAGLPDG-VPQGLLGWMMGLGGVLVFLLAPVIGVWADTPQ
:*: ***. ** .: . . ** .*: : .*** ***.::*
Mflv_2546|M.gilvum_PYR-GCK RRRRALTVLTGMVVLLTASLSLIRDDHHYLWPALVLLACTAACSELATVP
Mvan_4097|M.vanbaalenii_PYR-1 RRRRALAILTGLVVMLTASMSLIRDDHRYLWPGLILLACTAACGELSTVP
MSMEG_4721|M.smegmatis_MC2_155 RRRPALAVLTGCVVVVTASMSLIRDDHSYLWAGLVLLALAGACGELASVP
TH_1384|M.thermoresistible__bu RRRAALGVLTGLTVALTAAMSLIRDDHRYLWPALVLLACAAATSELATVP
Mb2536c|M.bovis_AF2122/97 RRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVP
Rv2508c|M.tuberculosis_H37Rv RRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVP
MLBr_00430|M.leprae_Br4923 RRRVTLGVLTVLAVALTCGMSFIRDQPSYLWAGLMLLAGTAACGDLASVP
MAV_1667|M.avium_104 RRRVALSVLTALAVTLTGSMFFIRDRPGYLWAGLVLLGATAACGDLASVP
MMAR_3855|M.marinum_M RRRVALGVLTSVTVVLTCAMFLIHDSPGYLWAGLALLAATAACSDLASVP
MUL_3787|M.ulcerans_Agy99 RRRVALGVLTSVTVALTCAMFLIHDSPGYLWAGLALLAATAACSDLASVP
MAB_1538|M.abscessus_ATCC_1997 RRRVALGTLTTLVVAVATAMSMVREDNRYLWLGLGLYCAGSVFNELAQVP
*** :* ** .* :: .: :::: *** .* * .. .:*: **
Mflv_2546|M.gilvum_PYR-GCK YNAMLRELSTPRTSGRISGFGLALGYFGSVLALLVVYLGFISGGG----D
Mvan_4097|M.vanbaalenii_PYR-1 YNAMLRDLSTPQTSGRVSGFGLALGYFGSVLALLVVYVGFIAGAG----D
MSMEG_4721|M.smegmatis_MC2_155 YNAMLRQLSTPDNSGRVSALGLALGYSGIVVLLVLVYFGFIAGDG----D
TH_1384|M.thermoresistible__bu YNAMLRQLSTPQNSGRVSGFGWAMGYFGSVTLLLVVYAGFIAGEG----D
Mb2536c|M.bovis_AF2122/97 YNAMLRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSG----S
Rv2508c|M.tuberculosis_H37Rv YNAMLRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSG----S
MLBr_00430|M.leprae_Br4923 YNAMLRQLSTPATAGRISGLGWASGYVGSVVLLLLIYLGFISGTG----E
MAV_1667|M.avium_104 YNAMLRQLSTPRTAGRISGFGWAAGYVGSVLLLLVIYTGFIAGSGSGPDA
MMAR_3855|M.marinum_M YNSMLRQLSTPTTASRISGFGWASGYVGSVVLLILIYLGFVAGSG----A
MUL_3787|M.ulcerans_Agy99 YNSMLRQLSTPTTASRISGFGWASGYVGSVVLLILIYLGFVAGSG----A
MAB_1538|M.abscessus_ATCC_1997 YNAMLHGLTTPANASRVSGLGLAAAYIGGVLVLLLCYLGFISGDG----P
**:**: *:** .:.*:*.:* * .* * * *:: * **::* *
Mflv_2546|M.gilvum_PYR-GCK TRGLLALPAADGQNVRAAMLLVAAWFALFALPLLISAPRHT--GPETAPA
Mvan_4097|M.vanbaalenii_PYR-1 TRGLLHLPVADGQNVRAAMLLVAAWFAVFALPLLISPPPVL--AQTPPPR
MSMEG_4721|M.smegmatis_MC2_155 TRGLLGLPVADGQNVRAVMLLAAAWLALFAVPVFFAVPSPH--VSVPSAR
TH_1384|M.thermoresistible__bu RRGLLGLPVADGLNVRAAMLLTAAWFLLFALPVLITVPSPP--DDGHRAR
Mb2536c|M.bovis_AF2122/97 QRGLLQLPVANGLNVRMAMLVAAAWLALLGLPLLLVAHRLPDSGAASHPS
Rv2508c|M.tuberculosis_H37Rv QRGLLQLPVANGLNVRMAMLVAAAWLALLGLPLLLVAHRLPDSGAASHPS
MLBr_00430|M.leprae_Br4923 LRGLLQLPTHDGIYVRAAMLLAAAWLALLALPLLLTAHRLPSLGEVSHPT
MAV_1667|M.avium_104 TRGLLRVPLRDGLYVREAMLVAAAWLALFALPLLFVAHRLTESAEGYRPT
MMAR_3855|M.marinum_M HRGLLQLPAHDGFNIRVAMLLAAAWLAVLASPLLLVAHRLPDVGTVPQPA
MUL_3787|M.ulcerans_Agy99 HRGLLQLPAHDGFNIRVAMLLAAAWLAVLASPLLLVAHRLPDVGTVPQPA
MAB_1538|M.abscessus_ATCC_1997 TRGLFQVPAADGYDVRVSALLAAAWFAVFALPLVLTR-PVPDPAAPPPSS
***: :* :* :* *:.***: ::. *:.: .
Mflv_2546|M.gilvum_PYR-GCK VGFLGAYRRLWQEIGREWRRDRNFVYYLGSSAVFRDGLTGVFTFGAVLGV
Mvan_4097|M.vanbaalenii_PYR-1 VGFIGAYRRLWHDLRAEWRRDRNLVYYLGASAIFRDGLTGVFTFGAVLGV
MSMEG_4721|M.smegmatis_MC2_155 TSFIGAYRKLWSEVRSEWERDRNIVYYLLASAVFRDGLAGVFTFGAVLGV
TH_1384|M.thermoresistible__bu TGFLGAYRRLAAELAGEWRRDRNVVYYLIASAVFRDGLAGVFAFGAVLGV
Mb2536c|M.bovis_AF2122/97 TGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVLGV
Rv2508c|M.tuberculosis_H37Rv TGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVLGV
MLBr_00430|M.leprae_Br4923 S-MLGGYRKLWSEVSAEWRRDRNLVYFLVASALFRDGLAATLGFGAVLGV
MAV_1667|M.avium_104 S-MLGGYRKLWTEVREEWRRDRNLVYFLFASALFRDGLAAIFAFGAVLGV
MMAR_3855|M.marinum_M TRMLGAYRKLWADISSEWRRDRNLVYFLIASAIFRDGLAAMFAFGAVLGV
MUL_3787|M.ulcerans_Agy99 TRMLGAYRKLWADISSEWRRDRNLVYFLIASAIFRDGLAAMFAFGAVLGA
MAB_1538|M.abscessus_ATCC_1997 PGVLGVYRELWRDLVEQWHMDRRIIYFLVASAIFRDGMVAMFALTPVIAN
.:* **.* :: :*. **..:*:* :**:****:.. : : .*:.
Mflv_2546|M.gilvum_PYR-GCK NVYGVSQADVLLFGVAACVVAALGSVAGGRVDDRVGSKPVIVASLVALIA
Mvan_4097|M.vanbaalenii_PYR-1 QVYGVSSADVLLFGVAACVVAAVGSVIGGRLDDRVGSKHVIVASLVSMIV
MSMEG_4721|M.smegmatis_MC2_155 SVYGISDADVLLFGISACVIAAIGAVVGGQLDDRIGSKPIIVGSLAAMIT
TH_1384|M.thermoresistible__bu TVYGVSEADVLLFGVCASVIAAIGAVLGGLVDDRVGSKPVIIGSLAAMIA
Mb2536c|M.bovis_AF2122/97 NAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIA
Rv2508c|M.tuberculosis_H37Rv NAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIA
MLBr_00430|M.leprae_Br4923 NAYGISQANVLMFGVVASLVAAVGAVLGGFVDHRIGSKRVIVGSLVAIIV
MAV_1667|M.avium_104 NVYGISQADVLVFGVAASVVAAVGAVLGGFVDHRVGSKPVIVASLLAIVV
MMAR_3855|M.marinum_M NVYGLTQADVLLFGVAASVVAAVGAVVGGFVDHRVGSKPVIVASLASILI
MUL_3787|M.ulcerans_Agy99 NVYGLTQADVLLFGVAASVVAAVGAVVGGFVDHRVGSKPVIVASLASILI
MAB_1538|M.abscessus_ATCC_1997 GVFHLSGADITLFGVAGNVMAAVGAVVGGLVDTRLGSKGIIVGSLAVIVS
.: :: *:: :** . ::**:*:* ** :* *:*** :*:.** ::
Mflv_2546|M.gilvum_PYR-GCK VGLTLMVLSGPMAFWACGLLLCLFIGPTLSSARTLMMRMSAHGKEGVTFG
Mvan_4097|M.vanbaalenii_PYR-1 VGLVLMVLSGVLAFWVCGLLLCLFIGPTLSSARTLMLRMCAHGKEGVTFG
MSMEG_4721|M.smegmatis_MC2_155 AGVVMMVLSGPVAFWACGLALCLFIGPTQSSARTLMLRMSAEGKEGVAFG
TH_1384|M.thermoresistible__bu TGLTLLNLSGAAAFWICGLLLCMFIGPTQSSARTLMLRMATLGKEGVAFG
Mb2536c|M.bovis_AF2122/97 AALTLLTLSGPTAFWACGLLLCVFIGPAQSSARALLLHMAQHGKEGVAFG
Rv2508c|M.tuberculosis_H37Rv AALTLLTLSGPTAFWACGLLLCVFIGPAQSSARALLLHMAQHGKEGVAFG
MLBr_00430|M.leprae_Br4923 TALTLMTLSGPLAFWVCGLVLCLFIGPSQSSSRALLLHMAKHGREGVAFG
MAV_1667|M.avium_104 LGLTLMALSGPVAFWACGLLLCMFIGPSQSSSRALLLQMAKHGREGVAFG
MMAR_3855|M.marinum_M SAIVLMVLSGATAFWVCGLLLCLFIGPSQSSARALLLRMAPHGKEGVAFG
MUL_3787|M.ulcerans_Agy99 SAIVLMVLSGATAFWVCGLLLCLFIGPSQSSARALLLRMAPHGKEGVAFG
MAB_1538|M.abscessus_ATCC_1997 LGIVMMFLTGQPAFWICGLAIAAFVGPPQSAARTLVLRMAPVGREAFVFG
.:.:: *:* *** *** :. *:**. *::*:*:::*. *:*...**
Mflv_2546|M.gilvum_PYR-GCK LYTTAGRAATFLAPWLFSVFIDVFDSYRAGMGGLVFVLALGLLLFLPVRV
Mvan_4097|M.vanbaalenii_PYR-1 FYTTAGRAATFLAPWLFSLSIDVFDSPRAGMGGLVAVLVLGLLLFLPVRA
MSMEG_4721|M.smegmatis_MC2_155 LYTTVGRAVSFLAPWLFFMFIDIFGTDRAGMGGLCLVLVAGLVGMAAVRT
TH_1384|M.thermoresistible__bu LYTTTGRAMSFLSPWMFFTFIDLFGTDRAGMAGLCVVLVAGLVAMLAVRV
Mb2536c|M.bovis_AF2122/97 LYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVLTTGLLLMLRVQV
Rv2508c|M.tuberculosis_H37Rv LYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVLTTGLLLMLRVQV
MLBr_00430|M.leprae_Br4923 LYTMTGRAASFVAPWSFSIFVDGFGVVRAGLGGISVVLLAGLLGMLMVRV
MAV_1667|M.avium_104 LYTMTGRAVSFVAPWLFSVFVDAFGAVRAGLGGISLVLTAGLLAMLAVRV
MMAR_3855|M.marinum_M LYTMTGRAVAFLGPWLFSIFVDIFSAVRAGLGGICLVLAVGLVGMLVVRV
MUL_3787|M.ulcerans_Agy99 LYTMTGHAVAFLGPWLFSIFVDIFSAVRAGLGGICLVLAVGLVGMLVVGV
MAB_1538|M.abscessus_ATCC_1997 LYTMTGRAVSFVGPWLFATFALLFHATRAGIAGPVLMIGLGMVAVILVKV
:** .*:* :*:.** * * ***:.* :: *:: . * .
Mflv_2546|M.gilvum_PYR-GCK PPRHGATVSASARRS--------
Mvan_4097|M.vanbaalenii_PYR-1 PHRRDPV----------------
MSMEG_4721|M.smegmatis_MC2_155 PERVTAR----------------
TH_1384|M.thermoresistible__bu PRRAG------------------
Mb2536c|M.bovis_AF2122/97 SRHGGALTTAQSS----------
Rv2508c|M.tuberculosis_H37Rv SRHGGALTTAQSS----------
MLBr_00430|M.leprae_Br4923 PTRREAAAVGLSWWRSQARRGQV
MAV_1667|M.avium_104 P-RRAPVAVEAA-----------
MMAR_3855|M.marinum_M PRHGGVVVTETT-----------
MUL_3787|M.ulcerans_Agy99 PRHGGVVVTETT-----------
MAB_1538|M.abscessus_ATCC_1997 PRYDPVRDEIVSGAG--------
.