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SYVPERDAAGLPEELSAVDQLLHRGEANPRTRSGIMGVELLDTTPDWERFRTRFDHASRKVVRLRQKVVM PTLPTAAPRWVVDPDFNLDYHVRRVRVPGPGTLRQVLDLAEVAMQSPMDITRPLWSATLVEGLADGRAAT ILHLSHAVSDAVGGVEMFASIYDLERDPEPDTPPPLPIPQDLSPGELMREGINRLPGSIAGGVLGALGGA ARAVTKVVRDPISAVSGVVDYAMSGTRVMAPAAEPSPLLRRRSLASRSEAIDIPFGDFHRAAKAAGGSIN DAYLAGVCGALRLYHDAKGVPIDSLPMAVPVNLRAEDDPAGGNRFAGVNLSAPIGIEDAEQRIKSVRSQM TSLREERAIDVVGAIAPVLSLLPDTILESVAGSVVNSDVQASNVPIYPGDTFLAGAKILRHYGLGPLPGV AMMVVLISRGGYITVTVRYDRAAITDGALFARCLQQGFDEVLALGGEVRCTPASFDPEPGTNIGGAQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4705 | - | - | 100% (488) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_3933 | - | 1e-68 | 34.44% (482) | hypothetical protein MSMEG_3933 |
| M. smegmatis MC2 155 | MSMEG_1882 | - | 3e-27 | 26.93% (479) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2509c | - | 0.0 | 70.64% (470) | hypothetical protein Mb2509c |
| M. gilvum PYR-GCK | Mflv_2563 | - | 0.0 | 73.35% (469) | hypothetical protein Mflv_2563 |
| M. tuberculosis H37Rv | Rv2484c | - | 0.0 | 70.64% (470) | hypothetical protein Rv2484c |
| M. leprae Br4923 | MLBr_01244 | - | 1e-177 | 64.73% (465) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_4544c | - | 6e-31 | 30.32% (409) | hypothetical protein MAB_4544c |
| M. marinum M | MMAR_3835 | - | 0.0 | 70.23% (477) | hypothetical protein MMAR_3835 |
| M. avium 104 | MAV_1686 | - | 0.0 | 70.45% (467) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_1039 | - | 0.0 | 75.00% (480) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_3765 | - | 0.0 | 68.53% (483) | hypothetical protein MUL_3765 |
| M. vanbaalenii PYR-1 | Mvan_4076 | - | 0.0 | 75.00% (488) | hypothetical protein Mvan_4076 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2563|M.gilvum_PYR-GCK --MSNSSGLDAAGLPEELSPLDQILHRGEANPRTRSGIMTIELLDTTPDW
Mvan_4076|M.vanbaalenii_PYR-1 --MSNEPELDAAGLPEELSPLDQILHRGEGNPRTRSGIMTLELLDTTPDW
TH_1039|M.thermoresistible__bu --MSDVPELDAAGLPEELSGLDQILHRGEANPRTRSGIMAVELLDTTPDW
MSMEG_4705|M.smegmatis_MC2_155 --MSYVPERDAAGLPEELSAVDQLLHRGEANPRTRSGIMGVELLDTTPDW
Mb2509c|M.bovis_AF2122/97 ----MAESGESPRLSDELGPVDYLMHRGEANPRTRSGIMALELLDGTPDW
Rv2484c|M.tuberculosis_H37Rv ----MAESGESPRLSDELGPVDYLMHRGEANPRTRSGIMALELLDGTPDW
MMAR_3835|M.marinum_M -------MAEAVGLSDELGPVDYLMHRGEANPRTRSGIMALELLDTTPDW
MUL_3765|M.ulcerans_Agy99 MAEWVVIMAEAVGLSDELGPVDYLMHRGEANPRTCSGIMALELLDTTPDW
MAV_1686|M.avium_104 --MTMTESVETIKLSDELGPVDYLMHRGEANPRTRSGIMALELLDTTPDW
MLBr_01244|M.leprae_Br4923 ----MADSVEGIGPFDELGALDYLLHRGEANPRTRAGIMAVELLDTTPDW
MAB_4544c|M.abscessus_ATCC_199 --MPFMPVSDSMFLIGETR--EHPFHVGGLQLFKPP-------VDAGPDY
: * : :* * : . . :* **:
Mflv_2563|M.gilvum_PYR-GCK DT-FRTRFEHASRKVLRLRQKVVTPTLPTTAPRWVVDPDFNLDFHLRRVR
Mvan_4076|M.vanbaalenii_PYR-1 DT-FRTRFDNASRKVLRLRQKVVTPTLPTAAPRWVVDPDFNLDFHVRRVR
TH_1039|M.thermoresistible__bu DR-FRTRFDHASRRVLRLRQKVVMPTLPTAPARWVVDPDFNLDYHVRRVR
MSMEG_4705|M.smegmatis_MC2_155 ER-FRTRFDHASRKVVRLRQKVVMPTLPTAAPRWVVDPDFNLDYHVRRVR
Mb2509c|M.bovis_AF2122/97 DR-FRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRVR
Rv2484c|M.tuberculosis_H37Rv DR-FRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRVR
MMAR_3835|M.marinum_M ER-FRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRVR
MUL_3765|M.ulcerans_Agy99 ER-FRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRVR
MAV_1686|M.avium_104 QQ-FRARFENASRRVLRLRQKVVVPTLPTAAPRWVIDPDFNLDFHVRRVR
MLBr_01244|M.leprae_Br4923 NR-FRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRVR
MAB_4544c|M.abscessus_ATCC_199 AEVFYEQLMSTTEVSSDFRKRPGQPLAVMGNLTWIVDDEVDWEYHVRRSA
* :: .:. :*:: * *::* :.: ::*:**
Mflv_2563|M.gilvum_PYR-GCK VPEPGTLRQVMDFAEIAAQSPLDISRPLWTATLIEGVQDGRAALMVHLSH
Mvan_4076|M.vanbaalenii_PYR-1 VPQPGTFRQVMDLAEIAAQSPLDISRPLWTATLIEGVENGRAALMVHLSH
TH_1039|M.thermoresistible__bu VPEPGTLRQVFDLAEVDMQSPLDISRPLWTATLVEGLRDGRAATMLHLSH
MSMEG_4705|M.smegmatis_MC2_155 VPGPGTLRQVLDLAEVAMQSPMDITRPLWSATLVEGLADGRAATILHLSH
Mb2509c|M.bovis_AF2122/97 VSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVSH
Rv2484c|M.tuberculosis_H37Rv VSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVSH
MMAR_3835|M.marinum_M VSEPGTLRDVFDLAEVILQSPLDISRPLWTATLVEGLADGKAATLLHVSH
MUL_3765|M.ulcerans_Agy99 VSEPGTLRDVFDLAEVILQSPLDISRPLWTATLVEGLADGKAATLLHVSH
MAV_1686|M.avium_104 VAEPGTLREVFDLAELILQSPMDISRPLWTATLVDGLADGKAATLLHVSH
MLBr_01244|M.leprae_Br4923 VPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQISH
MAB_4544c|M.abscessus_ATCC_199 LPRPARVRELLTVTSRWHSSPLDRHRPLWEMHVVEGLSDGRLAVYTKMHH
:. *. .*::: .:. .**:* **** :::*: *: * :: *
Mflv_2563|M.gilvum_PYR-GCK AVTDGVGGVEMFANLYDFEREPPPQPVPPMPVPTDLSPNDLMRSGLNRLP
Mvan_4076|M.vanbaalenii_PYR-1 AVTDGVGGVEMFANLYDFERDPPPQSTPPLPIPSDLSPNDLMRAGLNRLP
TH_1039|M.thermoresistible__bu AVTDGVGGVEMFASIYDFERDPPPGKEPPLPIPQDLTPNDLMWEGVGRLP
MSMEG_4705|M.smegmatis_MC2_155 AVSDAVGGVEMFASIYDLERDPEPDTPPPLPIPQDLSPGELMREGINRLP
Mb2509c|M.bovis_AF2122/97 AVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIPEDLSPNDLMRRGINHLP
Rv2484c|M.tuberculosis_H37Rv AVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIPEDLSPNDLMRRGINHLP
MMAR_3835|M.marinum_M AVTDGVGGVEMFAQIYDLERDPAPRPTPPLPIPQDLSPNDLMREGIGHLP
MUL_3765|M.ulcerans_Agy99 AVTDGVGGVEMFAQIYNLERDPAPRPTPPLPIPQDLSPNDLMREGIGHLP
MAV_1686|M.avium_104 AVTDGVGGVQMFAEIYDLERNPPPKPPPPLPVPQDLSPNDLMRQGINHLP
MLBr_01244|M.leprae_Br4923 AITDGVGSVEMFAEMYDLERDPPSRPRSPQPIPQDLSRNDLMLQGINHLP
MAB_4544c|M.abscessus_ATCC_199 AVIDGVGALRMMMRS--LSDDPDARDCQAVWAPAKRRAKSSIVSTTNTSA
*: *.**.:.*: :. :* . . * . . : . .
Mflv_2563|M.gilvum_PYR-GCK GTIVGGVVGAVAGAAQAVGHVVRDPVERLGSVFDYARSGVRVVGPVADPS
Mvan_4076|M.vanbaalenii_PYR-1 GTIVGGVRDALFGAAQAVGHVVRDPVSRLGSAFDYAMSGLRVVGPVADPS
TH_1039|M.thermoresistible__bu RSVVRGVRGLLGDTVRAVGKTLRDPRATVEGVLDYAASSARLVTPVAEPS
MSMEG_4705|M.smegmatis_MC2_155 GSIAGGVLGALGGAARAVTKVVRDPISAVSGVVDYAMSGTRVMAPAAEPS
Mb2509c|M.bovis_AF2122/97 IAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAEPS
Rv2484c|M.tuberculosis_H37Rv IAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAEPS
MMAR_3835|M.marinum_M IALVGGVAGAIAGAVSVAGRAVLDPAATVSGIVGYALSSVRVMNRAAEPS
MUL_3765|M.ulcerans_Agy99 IALVGGVAGAIAGAVSVAGRAVLDSAATVSGIVGYALSSVRVMNRAAEPS
MAV_1686|M.avium_104 FAVVGGVVSALSGAVSVAGRAMLEPASTVSGIVGYAMSGMRVLNRAAEPS
MLBr_01244|M.leprae_Br4923 VALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAEPS
MAB_4544c|M.abscessus_ATCC_199 IDLVKGAAGAVRQVVSIPPGLLKYG--------RHALSDPQLVKPLSAPH
:. *. . : .. : :. *. ::: : *
Mflv_2563|M.gilvum_PYR-GCK PILRRRS-LSSRSEAIDIEFSDLHRASKAAEGSINDAYLAGLCGALRLYH
Mvan_4076|M.vanbaalenii_PYR-1 PILRRRS-LSSRSDAIDIEFGDLHRAAKAAGGSINDAYLAGLCGALRLYH
TH_1039|M.thermoresistible__bu PILRRRS-LASRTGAIDIRFEDLRKAAKAGGGSINDAYLTGLCGALRLYH
MSMEG_4705|M.smegmatis_MC2_155 PLLRRRS-LASRSEAIDIPFGDFHRAAKAAGGSINDAYLAGVCGALRLYH
Mb2509c|M.bovis_AF2122/97 PLLRRRS-LTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRRYH
Rv2484c|M.tuberculosis_H37Rv PLLRRRS-LTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRRYH
MMAR_3835|M.marinum_M PLLRRRS-LTTRTEAIDIRLSELHKAAKAGGGSINDAYLAGLCGALRRYH
MUL_3765|M.ulcerans_Agy99 PLLRRRS-LTTRTEAIDIRLSELHKAAKAGGGSINDAYLAGLCGALRRYH
MAV_1686|M.avium_104 PLLRRRS-LATRSEAIDIPLADLHKAAKAGGGSINDAYLAGLCGALRRYH
MLBr_01244|M.leprae_Br4923 PLLRQRS-LATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRRYH
MAB_4544c|M.abscessus_ATCC_199 TMLNVSIGGARRFAAQTWSMARIKEAGKALGGTVNDVVLAMCGGALRTYL
.:*. : * * : ::.*.** *::**. *: **** *
Mflv_2563|M.gilvum_PYR-GCK ESMG-VPVDTLPMAVPVNLRSDADPAGGNRFVGVN------LAAPVGLSD
Mvan_4076|M.vanbaalenii_PYR-1 EAKG-VPIDTLPMAVPVNLRSEADPAGGNRFVGVN------LAAPIGVSD
TH_1039|M.thermoresistible__bu DALG-VPVDTLPMAVPVNLRSDADPAGGNRFTGVN------LAAPIGIVD
MSMEG_4705|M.smegmatis_MC2_155 DAKG-VPIDSLPMAVPVNLRAEDDPAGGNRFAGVN------LSAPIGIED
Mb2509c|M.bovis_AF2122/97 EALG-VPISTLPMAVPVNLRAEGDAAGGNQFTGVN------LAAPVGTID
Rv2484c|M.tuberculosis_H37Rv EALG-VPISTLPMAVPVNLRAEGDAAGGNQFTGVN------LAAPVGTID
MMAR_3835|M.marinum_M EALG-MPISTLPMAVPVNLRADADGAGGNRFTGVN------LAAPVGTAD
MUL_3765|M.ulcerans_Agy99 EALG-MPISTLPMAVPVNLRADADGAGGNRFTGVNRFTGVNLAAPVGTAD
MAV_1686|M.avium_104 EAFG-VPISTLPMAVPVNLRAEADTAGGNRFTGVN------LAAPIGTVD
MLBr_01244|M.leprae_Br4923 EALG-VSISTLPMAVPVNVRTEADVVGSNRFVGVT------LAAPLGTND
MAB_4544c|M.abscessus_ATCC_199 EEQNALPDKPLVAMCPVSIRAEGDQNAGNSITALL------ANLATDKPD
: . :. ..* **.:*:: * ..* :..: . . *
Mflv_2563|M.gilvum_PYR-GCK PAMRIKEIRAQMRSKR-----DERALDVVGAIAPLVSLLPDSVLETMAGS
Mvan_4076|M.vanbaalenii_PYR-1 PEVRIQDIRSQMTRKR-----DERAMDMVGAIAPVVSLLPDTVLESMAGS
TH_1039|M.thermoresistible__bu PVDRMQDVRAQMTRKR-----EERALDLLGMVAPVGSLLPDTVLEALAGT
MSMEG_4705|M.smegmatis_MC2_155 AEQRIKSVRSQMTSLR-----EERAIDVVGAIAPVLSLLPDTILESVAGS
Mb2509c|M.bovis_AF2122/97 PVARMKKIRAQMTQRR-----DEPAMNIIGSIAPVLSVLPTAVLEGITGS
Rv2484c|M.tuberculosis_H37Rv PVARMKKIRAQMTQRR-----DEPAMNIIGSIAPVLSVLPTAVLEGITGS
MMAR_3835|M.marinum_M PVARMKKIRAQMTQRR-----DEPAMNVVGSMAPVLSVLPTAVLEGISSS
MUL_3765|M.ulcerans_Agy99 PVARMKKIRAQMTQRR-----DEPAMNVVGSMAPVLSVLPTAVLEGISSS
MAV_1686|M.avium_104 PVSRMKKIRAQMTQRR-----DEPAMNIIGSLAPVLSVLPTAVLEGITGS
MLBr_01244|M.leprae_Br4923 PAARMQKIRSQMTQRR-----DEPAMNIIGSLAPLMTVLPASVLDFIVDS
MAB_4544c|M.abscessus_ATCC_199 PLERFSAIRDSVQAAKSVLSEMTPLQRMLVGALNGAPVLTGAVPGLVDRT
. *:. :* .: : :: .:*. :: : :
Mflv_2563|M.gilvum_PYR-GCK IVNSDVQASNVPVYAGDTFIAGAKVLRQYGLG-PLPGVAMMVVLISRSGY
Mvan_4076|M.vanbaalenii_PYR-1 FVNSDVQASNVPVYAGDTFIAGAKVLRQYGLG-PLPGVAMMVVLISRSGY
TH_1039|M.thermoresistible__bu VVNSDVQASNVPVILEDTYIAGAKVLRQYGLG-PLPGVAMMVVLVSRSGY
MSMEG_4705|M.smegmatis_MC2_155 VVNSDVQASNVPIYPGDTFLAGAKILRHYGLG-PLPGVAMMVVLISRGGY
Mb2509c|M.bovis_AF2122/97 VIGSDVQASNVPVYPGDTYLAGAKILRQYGIG-PLPGVAMMVVLISRGGW
Rv2484c|M.tuberculosis_H37Rv VIGSDVQASNVPVYPGDTYLAGAKILRQYGIG-PLPGVAMMVVLISRGGW
MMAR_3835|M.marinum_M VIGSDVQASNVPVYPGDTFVAGAKILRQYGIG-PLPGVAMMVVLISRGGW
MUL_3765|M.ulcerans_Agy99 VIGSDVQASNVPVYPGDTFVAGAKILRQYGIG-PLPGVAMMVVLISRGGW
MAV_1686|M.avium_104 VIGSDVQASNVPVFPGDTYIAGAKVLRQYGIG-PLPGVAMMVVLISRGGW
MLBr_01244|M.leprae_Br4923 VASSDVNASNIPAYPGDTYFAGAKILRQYGIG-PRPGVAMMAVLMSRGGF
MAB_4544c|M.abscessus_ATCC_199 APAFNVIISNVPGPRTDMFWNGFEMDGCYPASIPIDGVALNITCTSSGSS
:* **:* * : * :: * . * ***: . * ..
Mflv_2563|M.gilvum_PYR-GCK CTISTRYDRASITDPGLLAQCLLDGFDEVLALGGD--GRAVPATFSRVGA
Mvan_4076|M.vanbaalenii_PYR-1 CTVTARYDRAAITDPDLLAQCLLAGFDEVLALGGD--GRAVPATFTAQTT
TH_1039|M.thermoresistible__bu FTVTARYDRAAITDARLFAHCLLAGFNEVLALGGD--GRAEPASFEVDPA
MSMEG_4705|M.smegmatis_MC2_155 ITVTVRYDRAAITDGALFARCLQQGFDEVLALGGE--VRCTPASFDPEPG
Mb2509c|M.bovis_AF2122/97 CTVTVRYDRASVRNDELFAQCLQAGFDEILALAGDPAPRVLPASFDTQGA
Rv2484c|M.tuberculosis_H37Rv CTVTVRYDRASVRNDELFAQCLQAGFDEILALAGGPAPRVLPASFDTQGA
MMAR_3835|M.marinum_M ATITVRYDRASVRHDELFARCLVEGFDEILALAGDPAPRSIPASFTTV-S
MUL_3765|M.ulcerans_Agy99 ATITVRYDRASVRHDELFARCLVEGFDEILVLAGDPAPRSIPASFTTV-S
MAV_1686|M.avium_104 CTITVRYDRASVRDEALFAQCLLEGFDEILALAGDGAPRAVPASFTES--
MLBr_01244|M.leprae_Br4923 CTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPHAVPASFAARSS
MAB_4544c|M.abscessus_ATCC_199 MHFGLTGCRTSVPHLQRILAHLEDALTQLEESVA----------------
. *::: : * .: :: .
Mflv_2563|M.gilvum_PYR-GCK QEK---------------
Mvan_4076|M.vanbaalenii_PYR-1 PPVDSARLNGSGPQ----
TH_1039|M.thermoresistible__bu RLEALMSNAVVPSESAMR
MSMEG_4705|M.smegmatis_MC2_155 TNIGGAQ-----------
Mb2509c|M.bovis_AF2122/97 GSVPRSVSGS--------
Rv2484c|M.tuberculosis_H37Rv GSVPRSVSGS--------
MMAR_3835|M.marinum_M GSESRSVSNS--------
MUL_3765|M.ulcerans_Agy99 GSESRSVSNS--------
MAV_1686|M.avium_104 AVSARSASGS--------
MLBr_01244|M.leprae_Br4923 GSPAGWLSSS--------
MAB_4544c|M.abscessus_ATCC_199 ------------------