For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
AEFLTSTDEFMWSLGEDPVLRSTIVSLMILERAPEWDLVVERFERLTRVAPRFRQVVSPTVPPLPARWEE HAEFDLDWHLHRVSAPQPRTFPVLVNLAEVAMMTDLDRTRPLWEVTLVEGMADGSAALLCKFDHALTDGV GAVALAAALYDELEVLAASEGSKRPSGSVAAQVLETIRHPLTTAATAFDTAVSIYRAARPIAGPLSPVMR RRSATRRLEILEVSRSGLRRAGDAAGGTVNDAFLAAVTGGLRRYHDHHGVTVDQLMTSMPISVRGPHDGI GGNRATLVRFDVPVGEVDPMRRIREIHARTMAARGEKALAYTQLIAKALNVMPRGYVGSELRHVDFIASD VPGSPVPLKMGGAPIRSQYAFSPTLGAAVNTTLLSYVDVCAIGVNIDAGAIPDHDVLRDCLTAGFEETLS VHAAGGGPNPTTGGARPRRPHGAPRRPRRG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3933 | - | - | 100% (451) | hypothetical protein MSMEG_3933 |
| M. smegmatis MC2 155 | MSMEG_4705 | - | 1e-68 | 34.44% (482) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_3948 | - | 5e-31 | 29.30% (413) | acyltransferase, ws/dgat/mgat subfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2509c | - | 1e-67 | 35.45% (457) | hypothetical protein Mb2509c |
| M. gilvum PYR-GCK | Mflv_2004 | - | 1e-123 | 49.56% (452) | hypothetical protein Mflv_2004 |
| M. tuberculosis H37Rv | Rv2484c | - | 2e-68 | 35.67% (457) | hypothetical protein Rv2484c |
| M. leprae Br4923 | MLBr_01244 | - | 5e-61 | 32.09% (455) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 2e-30 | 27.51% (469) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_2649 | - | 1e-123 | 49.34% (452) | hypothetical protein MMAR_2649 |
| M. avium 104 | MAV_1686 | - | 3e-64 | 34.42% (459) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. thermoresistible (build 8) | TH_1039 | - | 1e-68 | 34.71% (461) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_3125 | - | 1e-121 | 47.92% (457) | hypothetical protein MUL_3125 |
| M. vanbaalenii PYR-1 | Mvan_4722 | - | 1e-124 | 49.22% (449) | hypothetical protein Mvan_4722 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2004|M.gilvum_PYR-GCK -------------MSEFMRNSDAFTWAME--SDPRLRSTVVTVLMLDRTP
Mvan_4722|M.vanbaalenii_PYR-1 -------------MSEFMRSSDAFTWSME--SDPRLRSTVVTVLMLDRTP
MMAR_2649|M.marinum_M -------------MTEFMRNSDAFTWSME--SDPRLRSTVVTVLLLDRSP
MUL_3125|M.ulcerans_Agy99 --------MRGVNMTEFMRNSDAFTWSME--SDPRLRSTVVTVLLLDRSP
MSMEG_3933|M.smegmatis_MC2_155 -------------MAEFLTSTDEFMWSLG--EDPVLRSTIVSLMILERAP
Mb2509c|M.bovis_AF2122/97 --MAES--GESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
Rv2484c|M.tuberculosis_H37Rv --MAES--GESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
MAV_1686|M.avium_104 MTMTES--VETIKLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDTTP
MLBr_01244|M.leprae_Br4923 --MADS--VEGIGPFDELGALDYLLHRGE--ANPRTRAGIMAVELLDTTP
TH_1039|M.thermoresistible__bu --MSDVPELDAAGLPEELSGLDQILHRGE--ANPRTRSGIMAVELLDTTP
MAB_3551c|M.abscessus_ATCC_199 ------MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRGGF
. : * * . : :
Mflv_2004|M.gilvum_PYR-GCK DWGEVCGRVERLSHEVPMMRQVVVE-TPPPAPPRWQDCTDFDLDFHMRRV
Mvan_4722|M.vanbaalenii_PYR-1 DWGEVRDRIERLSHELPMLRQVVVE-SPPPAPPRWQDCTDFDLDFHMRRV
MMAR_2649|M.marinum_M DWDEVRQRFDLISREMPMFRQRVVE-SPPPAPPRWEPDADFELDYHMRRV
MUL_3125|M.ulcerans_Agy99 DWDEVRQRFDLISREMPMFRQRVVE-SPPPASPRWEPDADFELDYHMRRV
MSMEG_3933|M.smegmatis_MC2_155 EWDLVVERFERLTRVAPRFRQVVSP-TVPPLPARWEEHAEFDLDWHLHRV
Mb2509c|M.bovis_AF2122/97 DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
Rv2484c|M.tuberculosis_H37Rv DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
MAV_1686|M.avium_104 DWQQFRARFENASRRVLRLRQKVVVPTLPTAAPRWVIDPDFNLDFHVRRV
MLBr_01244|M.leprae_Br4923 DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRV
TH_1039|M.thermoresistible__bu DWDRFRTRFDHASRRVLRLRQKVVMPTLPTAPARWVVDPDFNLDYHVRRV
MAB_3551c|M.abscessus_ATCC_199 TYEELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRS
: . .: ** * . * :*:: :*::*
Mflv_2004|M.gilvum_PYR-GCK AAPQDGTFESVLEMARLAQMEDFDRARPMWKLTLIEGLSDGRAAVLCCLH
Mvan_4722|M.vanbaalenii_PYR-1 AAPEGGSFDDVLELARLAQMEDFDRARPLWKITLIEGLPEGEAAVLCTFH
MMAR_2649|M.marinum_M TVSGAGTFEDVLEMARLAEMQDFDRARALWETTLIEGLQDGGAAVICKFH
MUL_3125|M.ulcerans_Agy99 TVSGAGTFEGVLEMARLAEMQDFDRARALWKTTLIEGLQDGGAAVICKFH
MSMEG_3933|M.smegmatis_MC2_155 SAPQPRTFPVLVNLAEVAMMTDLDRTRPLWEVTLVEGMADGSAALLCKFD
Mb2509c|M.bovis_AF2122/97 RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
Rv2484c|M.tuberculosis_H37Rv RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
MAV_1686|M.avium_104 RVAEPGTLREVFDLAELILQSPMDISRPLWTATLVDGLADGKAATLLHVS
MLBr_01244|M.leprae_Br4923 RVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQIS
TH_1039|M.thermoresistible__bu RVPEPGTLRQVFDLAEVDMQSPLDISRPLWTATLVEGLRDGRAATMLHLS
MAB_3551c|M.abscessus_ATCC_199 ALPSPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTH
. : : ::. :* :*.:* *::*: . *
Mflv_2004|M.gilvum_PYR-GCK HALTDGVGAVQIAMTLFGLSPELPPVDESPTAPP--QRSALGDYKDAARY
Mvan_4722|M.vanbaalenii_PYR-1 HALSDGVGGIQIAMTLFGLTPELAPTDETPEVS---RPSLLGDYRDAARY
MMAR_2649|M.marinum_M HALTDGVGGVQIAMHLFDLSAEVGAHPSLPAVAELPRHSWLDGYRDSWRY
MUL_3125|M.ulcerans_Agy99 HALTDGVGGVQIAMHLFDLSAEVGAHPSLSAVAELPRHSWLDGYRDSWRY
MSMEG_3933|M.smegmatis_MC2_155 HALTDGVGAVALAAALYDELEVLAASEG----------------------
Mb2509c|M.bovis_AF2122/97 HAVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIP-EDLSPNDLMRRGINH
Rv2484c|M.tuberculosis_H37Rv HAVTDGVGGVEMFAQIYDLERDPPPRSTPPQPIP-EDLSPNDLMRRGINH
MAV_1686|M.avium_104 HAVTDGVGGVQMFAEIYDLERNPPPKPPPPLPVP-QDLSPNDLMRQGINH
MLBr_01244|M.leprae_Br4923 HAITDGVGSVEMFAEMYDLERDPPSRPRSPQPIP-QDLSRNDLMLQGINH
TH_1039|M.thermoresistible__bu HAVTDGVGGVEMFASIYDFERDPPPGKEPPLPIP-QDLTPNDLMWEGVGR
MAB_3551c|M.abscessus_ATCC_199 QALVDGNSALSLGQVIFDRTARTPDFGEDIWVPE------HEPSTSELVA
:*: ** ..: : ::.
Mflv_2004|M.gilvum_PYR-GCK SVGLVGSAVTGALSVAPRLVVDSVRSPRRTLGNAAGLAASVYRTVRPVNA
Mvan_4722|M.vanbaalenii_PYR-1 GAGLVTDAVTGVLTGVPRLVYDGVRSPLRTLNSVAEMATSVYRTVRPVNA
MMAR_2649|M.marinum_M GVSMLARALTGAIKGGPLLLYNSLRRPIVTARSAAANAASVYRTVRPLNH
MUL_3125|M.ulcerans_Agy99 GVSMLARALTGAIKGGPLLLYNSLRRPVVTARSAAANTASVYRTVRPLNH
MSMEG_3933|M.smegmatis_MC2_155 -----SKRPSGSVAAQ---VLETIRHPLTTAATAFDTAVSIYRAARPIAG
Mb2509c|M.bovis_AF2122/97 LPIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAE
Rv2484c|M.tuberculosis_H37Rv LPIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAE
MAV_1686|M.avium_104 LPFAVVGGVVSALSGAVSVAGRAMLEPASTVSGIVGYAMSGMRVLNRAAE
MLBr_01244|M.leprae_Br4923 LPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAE
TH_1039|M.thermoresistible__bu LPRSVVRGVRGLLGDTVRAVGKTLRDPRATVEGVLDYAASSARLVTPVAE
MAB_3551c|M.abscessus_ATCC_199 GAVSEWLARPGARLEAVRNTVADVASLTGEIGELGERMVKVVRTAARGAA
. : . *
Mflv_2004|M.gilvum_PYR-GCK TGSPLMTRRTMNRRLGILEIPMPPLRDAAHRSGGALNDAFVAGVAGGLRQ
Mvan_4722|M.vanbaalenii_PYR-1 TGSPLMTERTLIRRLGVLEVPRPQLREAAHRSGGALNDAFVAGVAGGLRR
MMAR_2649|M.marinum_M TGSPLIKERSLIRHLGVLEVPRLQLREAAHRCGGALNDAFVAGVAGGLRL
MUL_3125|M.ulcerans_Agy99 TGSPLIKERSLIRHLGVLEVPRLQLREAAHRCGGALNDAFVAGVAGGLRL
MSMEG_3933|M.smegmatis_MC2_155 PLSPVMRRRSATRRLEILEVSRSGLRRAGDAAGGTVNDAFLAAVTGGLRR
Mb2509c|M.bovis_AF2122/97 P-SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRR
Rv2484c|M.tuberculosis_H37Rv P-SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRR
MAV_1686|M.avium_104 P-SPLLRRRSLATRSEAIDIPLADLHKAAKAGGGSINDAYLAGLCGALRR
MLBr_01244|M.leprae_Br4923 P-SPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRR
TH_1039|M.thermoresistible__bu P-SPILRRRSLASRTGAIDIRFEDLRKAAKAGGGSINDAYLTGLCGALRL
MAB_3551c|M.abscessus_ATCC_199 PRGPLNQRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGALRN
. .*: . : : :. : . . :**. :: : *.**
Mflv_2004|M.gilvum_PYR-GCK YHEKHG---AAVDALHLSMPISLRSEG------DAPGGNRITLMRFDIPA
Mvan_4722|M.vanbaalenii_PYR-1 YHEKHG---VGVGALHLTMPISLRASS------DAPGGNRITLMRFDIPV
MMAR_2649|M.marinum_M YHEKHG---VGVGDLHLTMPISLRTDD------DGMGGNRITIMRFDIPV
MUL_3125|M.ulcerans_Agy99 YHEKHG---VGVGDLHLTMPISLRTDD------DGMGGNRITIMRFDIPV
MSMEG_3933|M.smegmatis_MC2_155 YHDHHG---VTVDQLMTSMPISVRGPH------DGIGGNRATLVRFDVPV
Mb2509c|M.bovis_AF2122/97 YHEALG---VPISTLPMAVPVNLRAEG------DAAGGNQFTGVNLAAPV
Rv2484c|M.tuberculosis_H37Rv YHEALG---VPISTLPMAVPVNLRAEG------DAAGGNQFTGVNLAAPV
MAV_1686|M.avium_104 YHEAFG---VPISTLPMAVPVNLRAEA------DTAGGNRFTGVNLAAPI
MLBr_01244|M.leprae_Br4923 YHEALG---VSISTLPMAVPVNVRTEA------DVVGSNRFVGVTLAAPL
TH_1039|M.thermoresistible__bu YHDALG---VPVDTLPMAVPVNLRSDA------DPAGGNRFTGVNLAAPI
MAB_3551c|M.abscessus_ATCC_199 WLMSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDLPV
: * . . : :*:.: : . .. . . *
Mflv_2004|M.gilvum_PYR-GCK GLTDPGDRIRAIHARTEQVRREKSLPYTQAIAGVLNLVPRWYIG---SIL
Mvan_4722|M.vanbaalenii_PYR-1 DEADPAERIRQIHERTERVRNEKSLPHTQLIAGFLNRMPRWYIG---SIL
MMAR_2649|M.marinum_M GEADPAQRIKAIHERVSAVRQEKSLPHKQAIAGFLNLMPRWYIG---SVL
MUL_3125|M.ulcerans_Agy99 GEADPAQRIKAIHERVSAVRQEKSLPHTQAIAGFLNPMPRWYIG---SVL
MSMEG_3933|M.smegmatis_MC2_155 GEVDPMRRIREIHARTMAARGEKALAYTQLIAKALNVMPRGYVG---SEL
Mb2509c|M.bovis_AF2122/97 GTIDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLPTAVLEGITGSV
Rv2484c|M.tuberculosis_H37Rv GTIDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLPTAVLEGITGSV
MAV_1686|M.avium_104 GTVDPVSRMKKIRAQMTQRRDEPAMNIIGSLAPVLSVLPTAVLEGITGSV
MLBr_01244|M.leprae_Br4923 GTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLPASVLDFIVDSV
TH_1039|M.thermoresistible__bu GIVDPVDRMQDVRAQMTRKREERALDLLGMVAPVGSLLPDTVLEALAGTV
MAB_3551c|M.abscessus_ATCC_199 GEGNTVVRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAARVA
. :. *: : :: :* :*
Mflv_2004|M.gilvum_PYR-GCK RHV-----DFVASDVPGIPVPVSLGGAKVLMQYAFGPTI-GAAVNITLLT
Mvan_4722|M.vanbaalenii_PYR-1 RHV-----DFLASDVPGIPVPVSLGGANVRVQYAFGPTI-GSAVNVTLLT
MMAR_2649|M.marinum_M RHV-----DFLTSDVPGVPVPVFLGGAAVRTQYAFGPTI-GAAVNVTLLS
MUL_3125|M.ulcerans_Agy99 RHV-----DFLTSDVPGVPLPVFLGGAAVRTQYAFGPTI-GAAVNVTLLS
MSMEG_3933|M.smegmatis_MC2_155 RHV-----DFIASDVPGSPVPLKMGGAPIRSQYAFSPTL-GAAVNTTLLS
Mb2509c|M.bovis_AF2122/97 IGS-----DVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLIS
Rv2484c|M.tuberculosis_H37Rv IGS-----DVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLIS
MAV_1686|M.avium_104 IGS-----DVQASNVPVFPGDTYIAGAKVLRQYGIGPLP-GVAMMVVLIS
MLBr_01244|M.leprae_Br4923 ASS-----DVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMS
TH_1039|M.thermoresistible__bu VNS-----DVQASNVPVILEDTYIAGAKVLRQYGLGPLP-GVAMMVVLVS
MAB_3551c|M.abscessus_ATCC_199 STLPNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGLTS
:. .:::* :.** : * . * . .: * :
Mflv_2004|M.gilvum_PYR-GCK YVDTCALGIDADTGAIPDIDVFCDCLRAGFDEVLAVAAD-----------
Mvan_4722|M.vanbaalenii_PYR-1 YVDTCALGIDVDSGAIPDVEVFTDCLRDGFDEVLALADDD----------
MMAR_2649|M.marinum_M YVDSCALGINVDTGAIPDYDVFYSALVAGFDEVLALAV------------
MUL_3125|M.ulcerans_Agy99 YVDSCALGINVDTGAIPDYDVFYSALVAGFDEVLALAV------------
MSMEG_3933|M.smegmatis_MC2_155 YVDVCAIGVNIDAGAIPDHDVLRDCLTAGFEETLSVHAAGGGPNPTTGGA
Mb2509c|M.bovis_AF2122/97 RGGWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGDPAPR-----VL
Rv2484c|M.tuberculosis_H37Rv RGGWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGGPAPR-----VL
MAV_1686|M.avium_104 RGGWCTITVRYDRASVRDEALFAQCLLEGFDEILALAGDGAPR-----AV
MLBr_01244|M.leprae_Br4923 RGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPH-----AV
TH_1039|M.thermoresistible__bu RSGYFTVTARYDRAAITDARLFAHCLLAGFNEVLALGGDGRAEPASFEVD
MAB_3551c|M.abscessus_ATCC_199 YNGTVYYGINADREAMPDADMLPLLITEALDELLEAAQ------------
. * :: . :: : .::* *
Mflv_2004|M.gilvum_PYR-GCK --------------------
Mvan_4722|M.vanbaalenii_PYR-1 --------------------
MMAR_2649|M.marinum_M --------------------
MUL_3125|M.ulcerans_Agy99 --------------------
MSMEG_3933|M.smegmatis_MC2_155 RPRRPHGAPRRPRRG-----
Mb2509c|M.bovis_AF2122/97 PASFDTQGAGSVPRSVSGS-
Rv2484c|M.tuberculosis_H37Rv PASFDTQGAGSVPRSVSGS-
MAV_1686|M.avium_104 PASFTESAVS--ARSASGS-
MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS-
TH_1039|M.thermoresistible__bu PARLEALMSNAVVPSESAMR
MAB_3551c|M.abscessus_ATCC_199 --------------------