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STTAEAPIAETPSGGAVPLVEFKGVGKSYGNIIALKDINLRVGAGEVTCVLGDNGAGKSTLIKIIAGLHK PTEGEVLIDGKPTVFESPKDALNAGIATVYQDLAVVSLMPVWRNFFLGNELRKKNILRSLDINGMRATTI SELQKMGIDLPDVDAPIGSLSGGQRQCVAIARAIFFGARVLILDEPTAALGVKQSGMVLRYITAAKDQGF GVIFITHNPHHAYMVGDHFILLNRGRQKLDCTYDEISLETLTQEMAGGNELEALSHELGRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4656 | - | - | 100% (272) | sugar ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6802 | - | 5e-50 | 41.60% (250) | ABC transporter ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_1372 | - | 2e-47 | 41.74% (242) | ABC transporter ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-22 | 32.70% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_2607 | - | 1e-119 | 77.32% (269) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 1e-22 | 32.70% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01892 | - | 7e-21 | 29.55% (220) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_1655 | - | 4e-25 | 32.89% (225) | sulfate ABC transporter, ATP-binding protein SysA |
| M. marinum M | MMAR_3715 | cysA1 | 3e-22 | 33.18% (211) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. avium 104 | MAV_1785 | - | 6e-22 | 33.18% (211) | sulfate/thiosulfate import ATP-binding protein CysA |
| M. thermoresistible (build 8) | TH_1784 | - | 4e-26 | 31.78% (236) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 8e-23 | 32.13% (221) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_4009 | - | 1e-120 | 77.70% (269) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 --------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
Rv2397c|M.tuberculosis_H37Rv --------MT--------YAIVVADATKRYGDFVALDHVDFVVPTGSLTA
MAV_1785|M.avium_104 --------MTDAGTDRGDIAITVRDAYKRYGDFVALDHVDFVVPTGSLTA
MMAR_3715|M.marinum_M --MKKETSLTGPG--TGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTA
MUL_3658|M.ulcerans_Agy99 --------MTGPG--TGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLTA
MAB_1655|M.abscessus_ATCC_1997 --------MTAEN------TITVRGANKHYGDFAALDNIDFDVPSGSLTA
TH_1784|M.thermoresistible__bu MDSAGADVAVADPAAEAVPMISMRGVNKYFGSLHVLRDINLDVARGQVVV
Mflv_2607|M.gilvum_PYR-GCK MTISVEKASSDSKPGGKVPLVELKNIGKSYGNITALKDISLRVHAGEVTG
Mvan_4009|M.vanbaalenii_PYR-1 MTISVEKPSSDAQAGGKVPLVELKNVGKSYGNITALKDICLRVHAGEVTG
MSMEG_4656|M.smegmatis_MC2_155 MSTTAEAPIAETPSGGAVPLVEFKGVGKSYGNIIALKDINLRVGAGEVTC
MLBr_01892|M.leprae_Br4923 --------------MPMGVAIEVKGLTKSFGSSRIWEDVTLDIPAGEVSV
: . . * :*. .: : : *.:
Mb2419c|M.bovis_AF2122/97 LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR-----VPPQRRGIG
Rv2397c|M.tuberculosis_H37Rv LLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR-----VPPQRRGIG
MAV_1785|M.avium_104 LLGPSGSGKSTLLRTIAGLDQPDTGTVTIYGRDVTR-----VPPQRRGIG
MMAR_3715|M.marinum_M LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTR-----VPPQRRGIG
MUL_3658|M.ulcerans_Agy99 LLGPSGSGKSTLLRTIAGLDQPDSGNITINGRDVTR-----VPPQRRGIG
MAB_1655|M.abscessus_ATCC_1997 LLGPSGSGKSTLLRSIAGLDNPDSGTITINGRDVTG-----VPPQRRDIG
TH_1784|M.thermoresistible__bu VLGPSGSGKSTLCRTLNRLEPIDSGAISIDGVALPAEGR-ELARLRADVG
Mflv_2607|M.gilvum_PYR-GCK ILGDNGAGKSTLIKIIAGLHQQTDGELLVDGEPTRFAS--PADALGKGIA
Mvan_4009|M.vanbaalenii_PYR-1 ILGDNGAGKSTLIKIIAGLHQQTEGQLLVDGEPTKFAS--PAEALGKGIA
MSMEG_4656|M.smegmatis_MC2_155 VLGDNGAGKSTLIKIIAGLHKPTEGEVLIDGKPTVFES--PKDALNAGIA
MLBr_01892|M.leprae_Br4923 LLGPSGTGKSVFLKSLIGLLRPERGSILIDGTDIIECSAKELYEIRTLFG
:** .*:***.: : : * * : : * ..
Mb2419c|M.bovis_AF2122/97 FVFQHYAAFKHLTVRDNVAFG-LKIRKR------PKAEIKAKVDNLLQVV
Rv2397c|M.tuberculosis_H37Rv FVFQHYAAFKHLTVRDNVAFG-LKIRKR------PKAEIKAKVDNLLQVV
MAV_1785|M.avium_104 FVFQHYAAFKHLTVRDNVAYG-LKVRKR------PKAEIKAKVDNLLEVV
MMAR_3715|M.marinum_M FVFQHYAAFKHLTVRDNVAYG-LKIRKR------PKAEIRDKVDNLLEVV
MUL_3658|M.ulcerans_Agy99 FVFQHYAAFKHLTVRDNVAYG-LKIRKR------PKAEIRDKVDNLLEVV
MAB_1655|M.abscessus_ATCC_1997 FVFQHYAAFKHLTVWENVAFG-LKIRKK------PKAEIKKKVDDLLEVV
TH_1784|M.thermoresistible__bu MVFQQFNLFAHKTIVDNVALGPMKVRKT------PREQARAEAMALLERV
Mflv_2607|M.gilvum_PYR-GCK TVYQNLAVVPLMPVWRNFFLG-QELRKKRFPFSLDANAMRATTLTELAKM
Mvan_4009|M.vanbaalenii_PYR-1 TVYQNLAVVPLMPVWRNFFLG-QELRKKSFPFSLDADAMRATTLTELSKM
MSMEG_4656|M.smegmatis_MC2_155 TVYQDLAVVSLMPVWRNFFLG-NELRKKNILRSLDINGMRATTISELQKM
MLBr_01892|M.leprae_Br4923 VLFQDGALFGSMNLYDNTAFPLREHTKK------KESEIRDIVMEKLQLV
::*. . : * : * : . * :
Mb2419c|M.bovis_AF2122/97 GLSGFQSRYPN-QLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
Rv2397c|M.tuberculosis_H37Rv GLSGFQSRYPN-QLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
MAV_1785|M.avium_104 GLSGFQGRYPN-QLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVRE
MMAR_3715|M.marinum_M GLSGFHGRYPN-QLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
MUL_3658|M.ulcerans_Agy99 GLSGFHGRYPD-QLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVRE
MAB_1655|M.abscessus_ATCC_1997 GLSGFHTRYPA-QLSGGQRQRMALARALAVDPQVLLLDEPFGALDAKVRE
TH_1784|M.thermoresistible__bu GVADQADKYPA-QLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMIN
Mflv_2607|M.gilvum_PYR-GCK GIDLPDVDVPIGSLSGGQKQCVAIARAVFFGARVLILDEPTAALGVKQSG
Mvan_4009|M.vanbaalenii_PYR-1 GIDLPDVDVPIGSLSGGQKQCVAIARAVFFGARVLILDEPTAALGVKQSG
MSMEG_4656|M.smegmatis_MC2_155 GIDLPDVDAPIGSLSGGQRQCVAIARAIFFGARVLILDEPTAALGVKQSG
MLBr_01892|M.leprae_Br4923 GLGGDEKKFPG-EISGGMRKRAGLARALVLDPQIILCDEPDSGLDPVRTA
*: * .:*** :: .:**:: ....::: *** ..*.
Mb2419c|M.bovis_AF2122/97 ELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTD
Rv2397c|M.tuberculosis_H37Rv ELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGSPTD
MAV_1785|M.avium_104 DLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNQGRIEQIGSPTE
MMAR_3715|M.marinum_M DLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTE
MUL_3658|M.ulcerans_Agy99 DLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGSPTE
MAB_1655|M.abscessus_ATCC_1997 DLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNKGRIEQVGSPED
TH_1784|M.thermoresistible__bu EVLAVMSALAADG-MTMLVVTHEMGFARRASDRVVFMSDGAIVEDAEPAR
Mflv_2607|M.gilvum_PYR-GCK VVLKYITAAKEAG-FGVVFITHNPHHAHLVGDHFVLLNRGRQKLDCS---
Mvan_4009|M.vanbaalenii_PYR-1 VVLKYITAAKEAG-FGVVFITHNPHHAHLVGDHFVLLNRGRQKLDCT---
MSMEG_4656|M.smegmatis_MC2_155 MVLRYITAAKDQG-FGVIFITHNPHHAYMVGDHFILLNRGRQKLDCT---
MLBr_01892|M.leprae_Br4923 YLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGP-RE
: : :.:**: * . *.. .:
Mb2419c|M.bovis_AF2122/97 VYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGST
Rv2397c|M.tuberculosis_H37Rv VYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTAGST
MAV_1785|M.avium_104 VYDAPTNAFVMSFLGAVSTLNGTLVRPHDIRVGRTPEMAVAAEDGTAEST
MMAR_3715|M.marinum_M VYDAPANAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGEST
MUL_3658|M.ulcerans_Agy99 VYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTGEST
MAB_1655|M.abscessus_ATCC_1997 LYDRPANSFVMSFLGPVAKLNGILVRPHDIRVGRNADLARAAAEGTGETT
TH_1784|M.thermoresistible__bu FFEDPQTDRARDFLGKILHH------------------------------
Mflv_2607|M.gilvum_PYR-GCK -YDDITLEHLTQQMAGGDELEALSHELRAAKQ------------------
Mvan_4009|M.vanbaalenii_PYR-1 -YDDITLEHLTQEMAGGDELEALTHELRAAKS------------------
MSMEG_4656|M.smegmatis_MC2_155 -YDEISLETLTQEMAGGNELEALSHELGRK--------------------
MLBr_01892|M.leprae_Br4923 VLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGGAE
. :
Mb2419c|M.bovis_AF2122/97 GVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTV
Rv2397c|M.tuberculosis_H37Rv GVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREGDTV
MAV_1785|M.avium_104 GVARAIVDRVVKLGFEVRVELTSAATGGPFTAQITRGDAEALALREGDTV
MMAR_3715|M.marinum_M GVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTV
MUL_3658|M.ulcerans_Agy99 GVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEGDTV
MAB_1655|M.abscessus_ATCC_1997 GVTKATVDRVVYLGFEVRVELTSAATGEQFTAQITRGDAEALGLREGDPV
TH_1784|M.thermoresistible__bu --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4009|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_4656|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_01892|M.leprae_Br4923 EVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLEGA
Mb2419c|M.bovis_AF2122/97 YVRATRVPPIAGG---VSGVDDAGVERVKVTST------
Rv2397c|M.tuberculosis_H37Rv YVRATRVPPIAGG---VSGVDDAGVERVKVTST------
MAV_1785|M.avium_104 YVRATRVPPITAGATTVPAVSRDGADEATLTSA------
MMAR_3715|M.marinum_M YVRATRVPPIAGA---APAVPDDGAGSTPSAAQIGVGGQ
MUL_3658|M.ulcerans_Agy99 YVRATRVPPIAGA---APAVPDDGAGSTPRAAQIGVGGQ
MAB_1655|M.abscessus_ATCC_1997 YVRVTRVP--------------DVGELAEVAS-------
TH_1784|M.thermoresistible__bu ---------------------------------------
Mflv_2607|M.gilvum_PYR-GCK ---------------------------------------
Mvan_4009|M.vanbaalenii_PYR-1 ---------------------------------------
MSMEG_4656|M.smegmatis_MC2_155 ---------------------------------------
MLBr_01892|M.leprae_Br4923 HNYQAHEFGD-----------------------------