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TGLLPLIGVITLVVFGGLFAAIDAALSTVSIARIDELVRDERPGAARLATVVAERPRYINLVVLLRIICE VTATVLLASILDGLLGVSWGLVTAAAIMVVTSFVAMGVGPRTVGRQNAYSIALMSAIPLQALSVLLTPIS RLLVLLGNALTPGRGFRNGPFASEIELREVVDLAQQRGVVADEERRMIQSVFELGDTAAREVMVPRTEMV WIEADKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYLKDLVQQTYYSTNGGRDTTVAQVMRPAVFVPD SKPLDELLSEMQRDRNHMALLVDEYGATAGLVTIEDVLEEIVGEIADEYDTDEVAPVDEIDDHIYRVSAR LPIEDLAELYELELDEDLDVDTVGGLMAFELGRVPLPGAEVTWEGLRLRAEGGPDHRGRVRINTVLVCPT EPVEPELHTVPGDENSGRTRRGDRGDRSRGGEKDE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4495 | - | - | 100% (456) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3637 | - | 6e-29 | 31.05% (277) | CBS domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_3638 | - | 5e-11 | 25.00% (184) | CBS domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2387c | - | 0.0 | 77.07% (423) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2708 | - | 0.0 | 79.22% (438) | CBS domain-containing protein |
| M. tuberculosis H37Rv | Rv2366c | - | 0.0 | 77.07% (423) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1670 | - | 0.0 | 76.22% (429) | hypothetical protein MAB_1670 |
| M. marinum M | MMAR_3676 | - | 1e-177 | 74.94% (427) | hypothetical protein MMAR_3676 |
| M. avium 104 | MAV_2028 | - | 0.0 | 75.63% (435) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_1056 | - | 0.0 | 82.67% (427) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_3830 | - | 0.0 | 82.25% (417) | CBS domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2708|M.gilvum_PYR-GCK MTNVGQLISAIVLVAFGGLFAATDAALSTVSIARVEELVREERPGAVRLL
Mvan_3830|M.vanbaalenii_PYR-1 MSPVGQLISAIVLIFFGGVFAAIDAALSTVSMARVEELVREERPGAVRLA
TH_1056|M.thermoresistible__bu VSGLAQLVAAVVLVALAGVLAAVDSALNTVSTARVGELVRDERPGAVRLA
MSMEG_4495|M.smegmatis_MC2_155 MTGLLPLIGVITLVVFGGLFAAIDAALSTVSIARIDELVRDERPGAARLA
MAB_1670|M.abscessus_ATCC_1997 MSSIGLLLAAIALVGLGGAFAAIDAAINTVSRARVDELVREERPGAVRLS
Mb2387c|M.bovis_AF2122/97 MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
Rv2366c|M.tuberculosis_H37Rv MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
MMAR_3676|M.marinum_M MKGLPQLLGAIALVGLGGLFAAIDAAISTVSLARVQELVREARPGAVALS
MAV_2028|M.avium_104 MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALS
:. *:. :.*: :.* :** *:*:.*** **: ****: **** *
Mflv_2708|M.gilvum_PYR-GCK RLMVDRPRYINLIVLLRMTCEVSATVLMAAYLDDYLGVSRGLMAAAAIMT
Mvan_3830|M.vanbaalenii_PYR-1 RVMVERPRYINLIVLLRITCEVSATVLLAAFLDGTLGVTWGLVAAAAVMA
TH_1056|M.thermoresistible__bu RVVADRPKYVNLIVLLRIACEVSATVLLVAFLDGYLGLRWGMVTAAAVMV
MSMEG_4495|M.smegmatis_MC2_155 TVVAERPRYINLVVLLRIICEVTATVLLASILDGLLGVSWGLVTAAAIMV
MAB_1670|M.abscessus_ATCC_1997 AVIRERPRYVNLVVLLRTTCEILSTVFLVGYLTARISLGAALTISAIVMV
Mb2387c|M.bovis_AF2122/97 KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
Rv2366c|M.tuberculosis_H37Rv KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
MMAR_3676|M.marinum_M KVMEDRPRYINLVVLLRIVCEITATALLVVFFRHNLSMNGGLFLAAAIMV
MAV_2028|M.avium_104 KVMSERPRYINLVVLLRITCEITATVLLVVFLYDNFGLRWGLFGAAAIMV
:: :**:*:**:**** **: :*.::. : :.: .: :* :*.
Mflv_2708|M.gilvum_PYR-GCK VVSFVVVGVGPRTLGRQNAYTIALVTALPLQAISVVLTPISRLLVLIGNA
Mvan_3830|M.vanbaalenii_PYR-1 VVSFVAIGVGPRTLGRQNAYTIALVTALPLQAISVLLLPVSRLLVLIGNA
TH_1056|M.thermoresistible__bu VVSFVAIGVGPRTVGRQNAYSIALMAALPLQTISVLLTPISRLLVLLGNA
MSMEG_4495|M.smegmatis_MC2_155 VTSFVAMGVGPRTVGRQNAYSIALMSAIPLQALSVLLTPISRLLVLLGNA
MAB_1670|M.abscessus_ATCC_1997 VTSFVAIGVGPRTLGRQHAYSIALGAAVPLQVISVLLGPISRLLILLGNA
Mb2387c|M.bovis_AF2122/97 LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
Rv2366c|M.tuberculosis_H37Rv LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
MMAR_3676|M.marinum_M VTSFVVIGVGPRTLGRQNAYSISLGTAVPLQVISWLLMPISRLLVLLGNA
MAV_2028|M.avium_104 VTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNA
:.***.:******:***:**:*:* :.:**: :* :* *:****:::***
Mflv_2708|M.gilvum_PYR-GCK LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTAA
Mvan_3830|M.vanbaalenii_PYR-1 LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
TH_1056|M.thermoresistible__bu LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
MSMEG_4495|M.smegmatis_MC2_155 LTPGRGFRNGPFASEIELREVVDLAQQRGVVADEERRMIQSVFELGDTAA
MAB_1670|M.abscessus_ATCC_1997 VTPGRGFRNGPFASEIELREVVDMAQQRGVVADEERRMIQSVFELGDTPA
Mb2387c|M.bovis_AF2122/97 LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
Rv2366c|M.tuberculosis_H37Rv LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MMAR_3676|M.marinum_M LTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MAV_2028|M.avium_104 VTPGRGLRNGPFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPA
:*****:********:*******:******** :*****:********.*
Mflv_2708|M.gilvum_PYR-GCK REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVIGENVDDVVGVVYL
Mvan_3830|M.vanbaalenii_PYR-1 REVMVPRTEMVWIEYDKTAGQATSLAVRSGHSRIPVVGENVDDIVGVVYL
TH_1056|M.thermoresistible__bu REVMVPRTEMVWIEQDKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MSMEG_4495|M.smegmatis_MC2_155 REVMVPRTEMVWIEADKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MAB_1670|M.abscessus_ATCC_1997 REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVVGENVDDVVGVVFL
Mb2387c|M.bovis_AF2122/97 REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
Rv2366c|M.tuberculosis_H37Rv REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
MMAR_3676|M.marinum_M REVMVPRTEMVWIEGDKSPSQAMTLAVRSGHSRIPVVGENVDDILGVVYL
MAV_2028|M.avium_104 REVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGENVDDIVGVVYL
**********:*** **:..** .************:******::***:*
Mflv_2708|M.gilvum_PYR-GCK KDLVQKTYYSNNGGRDTAVSAVMRKPVFVPDSKPLDALLSEMQRDRVHMV
Mvan_3830|M.vanbaalenii_PYR-1 KDLVQRTYYSSNQGRDTSVSDVMRKPTFVPDSKPLDALLRDMQRDRVHMV
TH_1056|M.thermoresistible__bu KDLVQRTYYSTDGGRGTLVSEVMRPAVFVPDSKPLDELLREMQRDRNHMA
MSMEG_4495|M.smegmatis_MC2_155 KDLVQQTYYSTNGGRDTTVAQVMRPAVFVPDSKPLDELLSEMQRDRNHMA
MAB_1670|M.abscessus_ATCC_1997 KDLVQQTYYSVNGGRDVTVAQVMRPAVFVPDSKPLDELLREMQQHRKHMA
Mb2387c|M.bovis_AF2122/97 KDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMA
Rv2366c|M.tuberculosis_H37Rv KDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMA
MMAR_3676|M.marinum_M KDLVRQTFCAPDQGRKIDVSDLMRPAVFVPDSKPLDALLREMQHDRNHMA
MAV_2028|M.avium_104 KDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMA
****.:: . . ** *: :** ..********* ** :**:.* **.
Mflv_2708|M.gilvum_PYR-GCK LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGELSYRVSA
Mvan_3830|M.vanbaalenii_PYR-1 LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPVEDLGDQQYRVSA
TH_1056|M.thermoresistible__bu LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGDNRYRVSA
MSMEG_4495|M.smegmatis_MC2_155 LLVDEYGATAGLVTIEDVLEEIVGEIADEYDTDEVAPVDEIDDHIYRVSA
MAB_1670|M.abscessus_ATCC_1997 LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDHDEVAPVEELGDKMFRVSA
Mb2387c|M.bovis_AF2122/97 LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSA
Rv2366c|M.tuberculosis_H37Rv LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSA
MMAR_3676|M.marinum_M LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAETAPVEALGDKRFRVSA
MAV_2028|M.avium_104 LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVSA
******** ****:***************** *.**:: :.: :****
Mflv_2708|M.gilvum_PYR-GCK RLPIEDLSELYGIDFDEGLDVDTVGGLVALELGRVPLPGAEVEWDGLRLR
Mvan_3830|M.vanbaalenii_PYR-1 RLSIEDLGELYGIDFEEDLDVDTVGGLVALELGRVPLPGAEVTWDGLRLR
TH_1056|M.thermoresistible__bu RLPIEDLGELYGREFDGDLDVDTVGGLVALELGRVPLPGAEVTWDGLRLR
MSMEG_4495|M.smegmatis_MC2_155 RLPIEDLAELYELELDEDLDVDTVGGLMAFELGRVPLPGAEVTWEGLRLR
MAB_1670|M.abscessus_ATCC_1997 RLPIEDLGELYGIEFDEDLDVETVGGLLALDLGRVPLPGAKVASHGLLLQ
Mb2387c|M.bovis_AF2122/97 RLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
Rv2366c|M.tuberculosis_H37Rv RLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
MMAR_3676|M.marinum_M RLPIEDVGELYGIEFDGDLDVDTVGGLLALELGRVPLPGAEVIFHGLRLR
MAV_2028|M.avium_104 RLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
**.***:.*** ::: .***:*****:*::*********:* .** *:
Mflv_2708|M.gilvum_PYR-GCK AEGGPDPRGRVRIGTVLVSPVEPP--------NDDDEGHE----------
Mvan_3830|M.vanbaalenii_PYR-1 AEGGPDPRGRVRIGTVLVSPVEPA--------PDTAEGHE----------
TH_1056|M.thermoresistible__bu AEGGPDHRGRVRIGTVLVSPVEPED-------ADDTEDRDGADD------
MSMEG_4495|M.smegmatis_MC2_155 AEGGPDHRGRVRINTVLVCPTEPVEPELHTVPGDENSGRTRRGDRGDRSR
MAB_1670|M.abscessus_ATCC_1997 AEGGPDARGRVRIGTILVQPDPDAES------DEKAEERDE---------
Mb2387c|M.bovis_AF2122/97 AEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG-----
Rv2366c|M.tuberculosis_H37Rv AEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG-----
MMAR_3676|M.marinum_M AEGGPDHRGRVRIGTVLVSPMETEE-------TDGAGDGAAETGADG---
MAV_2028|M.avium_104 AEGGTDHRGRVRVGTVLLSPVE----------SDGSPDGEEPEHHD----
****.* *****:.*:*: * :
Mflv_2708|M.gilvum_PYR-GCK ------
Mvan_3830|M.vanbaalenii_PYR-1 ------
TH_1056|M.thermoresistible__bu ------
MSMEG_4495|M.smegmatis_MC2_155 GGEKDE
MAB_1670|M.abscessus_ATCC_1997 ------
Mb2387c|M.bovis_AF2122/97 ------
Rv2366c|M.tuberculosis_H37Rv ------
MMAR_3676|M.marinum_M ------
MAV_2028|M.avium_104 ------