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M. thermoresistible (build 8) TH_1056 ()

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 2083086 - 2084399
length: 438

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1056-100% (438)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
M. thermoresistible (build 8)TH_2796-2e-4032.08% (399) PUTATIVE protein of unknown function DUF21
M. thermoresistible (build 8)TH_2608-1e-2929.41% (306) PUTATIVE protein of unknown function DUF21

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2387c-0.077.91% (430) transmembrane protein
M. gilvum PYR-GCKMflv_2708-0.082.71% (428) CBS domain-containing protein
M. tuberculosis H37RvRv2366c-0.077.91% (430) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1670-0.076.50% (434) hypothetical protein MAB_1670
M. marinum MMMAR_3676-0.076.31% (439) hypothetical protein MMAR_3676
M. avium 104MAV_2028-0.077.29% (436) CBS domain-containing protein
M. smegmatis MC2 155MSMEG_4495-0.082.67% (427) CBS domain-containing protein
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3830-0.084.45% (431) CBS domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2708|M.gilvum_PYR-GCK          MTNVGQLISAIVLVAFGGLFAATDAALSTVSIARVEELVREERPGAVRLL
Mvan_3830|M.vanbaalenii_PYR-1       MSPVGQLISAIVLIFFGGVFAAIDAALSTVSMARVEELVREERPGAVRLA
TH_1056|M.thermoresistible__bu      VSGLAQLVAAVVLVALAGVLAAVDSALNTVSTARVGELVRDERPGAVRLA
MSMEG_4495|M.smegmatis_MC2_155      MTGLLPLIGVITLVVFGGLFAAIDAALSTVSIARIDELVRDERPGAARLA
MAB_1670|M.abscessus_ATCC_1997      MSSIGLLLAAIALVGLGGAFAAIDAAINTVSRARVDELVREERPGAVRLS
Mb2387c|M.bovis_AF2122/97           MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
Rv2366c|M.tuberculosis_H37Rv        MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
MMAR_3676|M.marinum_M               MKGLPQLLGAIALVGLGGLFAAIDAAISTVSLARVQELVREARPGAVALS
MAV_2028|M.avium_104                MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALS
                                    :.    *:. :.*: :.* :** *:*:.*** **: ****: ****  * 

Mflv_2708|M.gilvum_PYR-GCK          RLMVDRPRYINLIVLLRMTCEVSATVLMAAYLDDYLGVSRGLMAAAAIMT
Mvan_3830|M.vanbaalenii_PYR-1       RVMVERPRYINLIVLLRITCEVSATVLLAAFLDGTLGVTWGLVAAAAVMA
TH_1056|M.thermoresistible__bu      RVVADRPKYVNLIVLLRIACEVSATVLLVAFLDGYLGLRWGMVTAAAVMV
MSMEG_4495|M.smegmatis_MC2_155      TVVAERPRYINLVVLLRIICEVTATVLLASILDGLLGVSWGLVTAAAIMV
MAB_1670|M.abscessus_ATCC_1997      AVIRERPRYVNLVVLLRTTCEILSTVFLVGYLTARISLGAALTISAIVMV
Mb2387c|M.bovis_AF2122/97           KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
Rv2366c|M.tuberculosis_H37Rv        KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
MMAR_3676|M.marinum_M               KVMEDRPRYINLVVLLRIVCEITATALLVVFFRHNLSMNGGLFLAAAIMV
MAV_2028|M.avium_104                KVMSERPRYINLVVLLRITCEITATVLLVVFLYDNFGLRWGLFGAAAIMV
                                     :: :**:*:**:****  **: :*.::.  :   :.:  .:  :* :*.

Mflv_2708|M.gilvum_PYR-GCK          VVSFVVVGVGPRTLGRQNAYTIALVTALPLQAISVVLTPISRLLVLIGNA
Mvan_3830|M.vanbaalenii_PYR-1       VVSFVAIGVGPRTLGRQNAYTIALVTALPLQAISVLLLPVSRLLVLIGNA
TH_1056|M.thermoresistible__bu      VVSFVAIGVGPRTVGRQNAYSIALMAALPLQTISVLLTPISRLLVLLGNA
MSMEG_4495|M.smegmatis_MC2_155      VTSFVAMGVGPRTVGRQNAYSIALMSAIPLQALSVLLTPISRLLVLLGNA
MAB_1670|M.abscessus_ATCC_1997      VTSFVAIGVGPRTLGRQHAYSIALGAAVPLQVISVLLGPISRLLILLGNA
Mb2387c|M.bovis_AF2122/97           LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
Rv2366c|M.tuberculosis_H37Rv        LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
MMAR_3676|M.marinum_M               VTSFVVIGVGPRTLGRQNAYSISLGTAVPLQVISWLLMPISRLLVLLGNA
MAV_2028|M.avium_104                VTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNA
                                    :.***.:******:***:**:*:* :.:**: :* :* *:****:::***

Mflv_2708|M.gilvum_PYR-GCK          LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTAA
Mvan_3830|M.vanbaalenii_PYR-1       LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
TH_1056|M.thermoresistible__bu      LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
MSMEG_4495|M.smegmatis_MC2_155      LTPGRGFRNGPFASEIELREVVDLAQQRGVVADEERRMIQSVFELGDTAA
MAB_1670|M.abscessus_ATCC_1997      VTPGRGFRNGPFASEIELREVVDMAQQRGVVADEERRMIQSVFELGDTPA
Mb2387c|M.bovis_AF2122/97           LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
Rv2366c|M.tuberculosis_H37Rv        LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MMAR_3676|M.marinum_M               LTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MAV_2028|M.avium_104                VTPGRGLRNGPFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPA
                                    :*****:********:*******:******** :*****:********.*

Mflv_2708|M.gilvum_PYR-GCK          REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVIGENVDDVVGVVYL
Mvan_3830|M.vanbaalenii_PYR-1       REVMVPRTEMVWIEYDKTAGQATSLAVRSGHSRIPVVGENVDDIVGVVYL
TH_1056|M.thermoresistible__bu      REVMVPRTEMVWIEQDKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MSMEG_4495|M.smegmatis_MC2_155      REVMVPRTEMVWIEADKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MAB_1670|M.abscessus_ATCC_1997      REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVVGENVDDVVGVVFL
Mb2387c|M.bovis_AF2122/97           REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
Rv2366c|M.tuberculosis_H37Rv        REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
MMAR_3676|M.marinum_M               REVMVPRTEMVWIEGDKSPSQAMTLAVRSGHSRIPVVGENVDDILGVVYL
MAV_2028|M.avium_104                REVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGENVDDIVGVVYL
                                    **********:*** **:..** .************:******::***:*

Mflv_2708|M.gilvum_PYR-GCK          KDLVQKTYYSNNGGRDTAVSAVMRKPVFVPDSKPLDALLSEMQRDRVHMV
Mvan_3830|M.vanbaalenii_PYR-1       KDLVQRTYYSSNQGRDTSVSDVMRKPTFVPDSKPLDALLRDMQRDRVHMV
TH_1056|M.thermoresistible__bu      KDLVQRTYYSTDGGRGTLVSEVMRPAVFVPDSKPLDELLREMQRDRNHMA
MSMEG_4495|M.smegmatis_MC2_155      KDLVQQTYYSTNGGRDTTVAQVMRPAVFVPDSKPLDELLSEMQRDRNHMA
MAB_1670|M.abscessus_ATCC_1997      KDLVQQTYYSVNGGRDVTVAQVMRPAVFVPDSKPLDELLREMQQHRKHMA
Mb2387c|M.bovis_AF2122/97           KDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMA
Rv2366c|M.tuberculosis_H37Rv        KDLVEQTFCSTNGGRETTVARVMRPAVFVPDSKPLDALLREMQRDRNHMA
MMAR_3676|M.marinum_M               KDLVRQTFCAPDQGRKIDVSDLMRPAVFVPDSKPLDALLREMQHDRNHMA
MAV_2028|M.avium_104                KDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMA
                                    ****.::  . . **   *: :** ..********* ** :**:.* **.

Mflv_2708|M.gilvum_PYR-GCK          LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGELSYRVSA
Mvan_3830|M.vanbaalenii_PYR-1       LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPVEDLGDQQYRVSA
TH_1056|M.thermoresistible__bu      LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGDNRYRVSA
MSMEG_4495|M.smegmatis_MC2_155      LLVDEYGATAGLVTIEDVLEEIVGEIADEYDTDEVAPVDEIDDHIYRVSA
MAB_1670|M.abscessus_ATCC_1997      LLVDEYGAIAGLVTIEDVLEEIVGEIADEYDHDEVAPVEELGDKMFRVSA
Mb2387c|M.bovis_AF2122/97           LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSA
Rv2366c|M.tuberculosis_H37Rv        LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVSA
MMAR_3676|M.marinum_M               LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAETAPVEALGDKRFRVSA
MAV_2028|M.avium_104                LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVSA
                                    ******** ****:*****************  *.**:: :.:  :****

Mflv_2708|M.gilvum_PYR-GCK          RLPIEDLSELYGIDFDEGLDVDTVGGLVALELGRVPLPGAEVEWDGLRLR
Mvan_3830|M.vanbaalenii_PYR-1       RLSIEDLGELYGIDFEEDLDVDTVGGLVALELGRVPLPGAEVTWDGLRLR
TH_1056|M.thermoresistible__bu      RLPIEDLGELYGREFDGDLDVDTVGGLVALELGRVPLPGAEVTWDGLRLR
MSMEG_4495|M.smegmatis_MC2_155      RLPIEDLAELYELELDEDLDVDTVGGLMAFELGRVPLPGAEVTWEGLRLR
MAB_1670|M.abscessus_ATCC_1997      RLPIEDLGELYGIEFDEDLDVETVGGLLALDLGRVPLPGAKVASHGLLLQ
Mb2387c|M.bovis_AF2122/97           RLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
Rv2366c|M.tuberculosis_H37Rv        RLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
MMAR_3676|M.marinum_M               RLPIEDVGELYGIEFDGDLDVDTVGGLLALELGRVPLPGAEVIFHGLRLR
MAV_2028|M.avium_104                RLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
                                    **.***:.***  ::: .***:*****:*::*********:*  .** *:

Mflv_2708|M.gilvum_PYR-GCK          AEGGPDPRGRVRIGTVLVSPVEPP--------NDDDEGHE----------
Mvan_3830|M.vanbaalenii_PYR-1       AEGGPDPRGRVRIGTVLVSPVEPA--------PDTAEGHE----------
TH_1056|M.thermoresistible__bu      AEGGPDHRGRVRIGTVLVSPVEPED-------ADDTEDRDGADD------
MSMEG_4495|M.smegmatis_MC2_155      AEGGPDHRGRVRINTVLVCPTEPVEPELHTVPGDENSGRTRRGDRGDRSR
MAB_1670|M.abscessus_ATCC_1997      AEGGPDARGRVRIGTILVQPDPDAES------DEKAEERDE---------
Mb2387c|M.bovis_AF2122/97           AEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG-----
Rv2366c|M.tuberculosis_H37Rv        AEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG-----
MMAR_3676|M.marinum_M               AEGGPDHRGRVRIGTVLVSPMETEE-------TDGAGDGAAETGADG---
MAV_2028|M.avium_104                AEGGTDHRGRVRVGTVLLSPVE----------SDGSPDGEEPEHHD----
                                    ****.* *****:.*:*: *             :                

Mflv_2708|M.gilvum_PYR-GCK          ------
Mvan_3830|M.vanbaalenii_PYR-1       ------
TH_1056|M.thermoresistible__bu      ------
MSMEG_4495|M.smegmatis_MC2_155      GGEKDE
MAB_1670|M.abscessus_ATCC_1997      ------
Mb2387c|M.bovis_AF2122/97           ------
Rv2366c|M.tuberculosis_H37Rv        ------
MMAR_3676|M.marinum_M               ------
MAV_2028|M.avium_104                ------