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MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYINLVVLLRITC EITATVLLVVFLYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPI SRLLVVLGNAVTPGRGLRNGPFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPAREVMVPRTEM IWIESDKSASQAINLAVRSGHSRIPVIGENVDDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVP DSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVSA RLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHAEGGTDHRGRVRVGTVLLSP VESDGSPDGEEPEHHD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2028 | - | - | 100% (436) | CBS domain-containing protein |
| M. avium 104 | MAV_2878 | - | 2e-32 | 30.92% (304) | CBS domain-containing protein |
| M. avium 104 | MAV_2879 | - | 8e-12 | 28.07% (171) | CBS domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2387c | - | 0.0 | 84.10% (434) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_2708 | - | 0.0 | 74.77% (436) | CBS domain-containing protein |
| M. tuberculosis H37Rv | Rv2366c | - | 0.0 | 84.10% (434) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1670 | - | 1e-180 | 76.58% (427) | hypothetical protein MAB_1670 |
| M. marinum M | MMAR_3676 | - | 0.0 | 83.49% (430) | hypothetical protein MMAR_3676 |
| M. smegmatis MC2 155 | MSMEG_4495 | - | 0.0 | 75.63% (435) | CBS domain-containing protein |
| M. thermoresistible (build 8) | TH_1056 | - | 0.0 | 77.29% (436) | PROBABLE CONSERVED TRANSMEMBRANE PROTEIN |
| M. ulcerans Agy99 | MUL_3669 | - | 2e-05 | 31.96% (97) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3830 | - | 0.0 | 76.76% (426) | CBS domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2708|M.gilvum_PYR-GCK MTNVGQLISAIVLVAFGGLFAATDAALSTVSIARVEELVREERPGAVRLL
Mvan_3830|M.vanbaalenii_PYR-1 MSPVGQLISAIVLIFFGGVFAAIDAALSTVSMARVEELVREERPGAVRLA
TH_1056|M.thermoresistible__bu VSGLAQLVAAVVLVALAGVLAAVDSALNTVSTARVGELVRDERPGAVRLA
MSMEG_4495|M.smegmatis_MC2_155 MTGLLPLIGVITLVVFGGLFAAIDAALSTVSIARIDELVRDERPGAARLA
MAB_1670|M.abscessus_ATCC_1997 MSSIGLLLAAIALVGLGGAFAAIDAAINTVSRARVDELVREERPGAVRLS
Mb2387c|M.bovis_AF2122/97 MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
Rv2366c|M.tuberculosis_H37Rv MTGYYQLLGSIVLIGLGGLFAAIDAAISTVSPARVDELVRDQRPGAGSLR
MMAR_3676|M.marinum_M MKGLPQLLGAIALVGLGGLFAAIDAAISTVSLARVQELVREARPGAVALS
MAV_2028|M.avium_104 MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALS
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2708|M.gilvum_PYR-GCK RLMVDRPRYINLIVLLRMTCEVSATVLMAAYLDDYLGVSRGLMAAAAIMT
Mvan_3830|M.vanbaalenii_PYR-1 RVMVERPRYINLIVLLRITCEVSATVLLAAFLDGTLGVTWGLVAAAAVMA
TH_1056|M.thermoresistible__bu RVVADRPKYVNLIVLLRIACEVSATVLLVAFLDGYLGLRWGMVTAAAVMV
MSMEG_4495|M.smegmatis_MC2_155 TVVAERPRYINLVVLLRIICEVTATVLLASILDGLLGVSWGLVTAAAIMV
MAB_1670|M.abscessus_ATCC_1997 AVIRERPRYVNLVVLLRTTCEILSTVFLVGYLTARISLGAALTISAIVMV
Mb2387c|M.bovis_AF2122/97 KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
Rv2366c|M.tuberculosis_H37Rv KVMADRPRYVNLVVLLRTSCEITATALLVVFIRYHFSMVWGLYLAAGIMV
MMAR_3676|M.marinum_M KVMEDRPRYINLVVLLRIVCEITATALLVVFFRHNLSMNGGLFLAAAIMV
MAV_2028|M.avium_104 KVMSERPRYINLVVLLRITCEITATVLLVVFLYDNFGLRWGLFGAAAIMV
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2708|M.gilvum_PYR-GCK VVSFVVVGVGPRTLGRQNAYTIALVTALPLQAISVVLTPISRLLVLIGNA
Mvan_3830|M.vanbaalenii_PYR-1 VVSFVAIGVGPRTLGRQNAYTIALVTALPLQAISVLLLPVSRLLVLIGNA
TH_1056|M.thermoresistible__bu VVSFVAIGVGPRTVGRQNAYSIALMAALPLQTISVLLTPISRLLVLLGNA
MSMEG_4495|M.smegmatis_MC2_155 VTSFVAMGVGPRTVGRQNAYSIALMSAIPLQALSVLLTPISRLLVLLGNA
MAB_1670|M.abscessus_ATCC_1997 VTSFVAIGVGPRTLGRQHAYSIALGAAVPLQVISVLLGPISRLLILLGNA
Mb2387c|M.bovis_AF2122/97 LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
Rv2366c|M.tuberculosis_H37Rv LASFVVVGVGPRTLGRQNAYSISLATALPLRLISWLLMPISRLLVLLGNA
MMAR_3676|M.marinum_M VTSFVVIGVGPRTLGRQNAYSISLGTAVPLQVISWLLMPISRLLVLLGNA
MAV_2028|M.avium_104 VTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNA
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2708|M.gilvum_PYR-GCK LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTAA
Mvan_3830|M.vanbaalenii_PYR-1 LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
TH_1056|M.thermoresistible__bu LTPGRGFRNGPFASEIELREVVDLAQQRGVVADDERRMIQSVFELGDTPA
MSMEG_4495|M.smegmatis_MC2_155 LTPGRGFRNGPFASEIELREVVDLAQQRGVVADEERRMIQSVFELGDTAA
MAB_1670|M.abscessus_ATCC_1997 VTPGRGFRNGPFASEIELREVVDMAQQRGVVADEERRMIQSVFELGDTPA
Mb2387c|M.bovis_AF2122/97 LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
Rv2366c|M.tuberculosis_H37Rv LTPGRGFRNGPFASEIELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MMAR_3676|M.marinum_M LTPGRGFRNGPFASEVELREVVDLAQQRGVVAADERRMIESVFELGDTPA
MAV_2028|M.avium_104 VTPGRGLRNGPFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPA
MUL_3669|M.ulcerans_Agy99 ------------------MRIADVLRNKGAVVTTIN---------PDATV
.:.*: :::*.*. . *:..
Mflv_2708|M.gilvum_PYR-GCK REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVIGENVDDVVGVVYL
Mvan_3830|M.vanbaalenii_PYR-1 REVMVPRTEMVWIEYDKTAGQATSLAVRSGHSRIPVVGENVDDIVGVVYL
TH_1056|M.thermoresistible__bu REVMVPRTEMVWIEQDKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MSMEG_4495|M.smegmatis_MC2_155 REVMVPRTEMVWIEADKTAGQATSLAVRSGHSRIPVIGENVDDIVGVVYL
MAB_1670|M.abscessus_ATCC_1997 REVMVPRTEMVWIESDKTAGQATSLAVRSGHSRIPVVGENVDDVVGVVFL
Mb2387c|M.bovis_AF2122/97 REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
Rv2366c|M.tuberculosis_H37Rv REVMVPRTEMIWIESDKTAGQAMTLAVRSGHSRIPVIGENVDDIVGVVYL
MMAR_3676|M.marinum_M REVMVPRTEMVWIEGDKSPSQAMTLAVRSGHSRIPVVGENVDDILGVVYL
MAV_2028|M.avium_104 REVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGENVDDIVGVVYL
MUL_3669|M.ulcerans_Agy99 RELFAG-----------LAEQNIGAMVVVG----------VEGVVGIVSE
**::. . * * * *:.::*:*
Mflv_2708|M.gilvum_PYR-GCK KDLVQKTYYSNNGGRDTAVSAVMRKPVFVP-DSKPLDALLSEMQRDRVHM
Mvan_3830|M.vanbaalenii_PYR-1 KDLVQRTYYSSNQGRDTSVSDVMRKPTFVP-DSKPLDALLRDMQRDRVHM
TH_1056|M.thermoresistible__bu KDLVQRTYYSTDGGRGTLVSEVMRPAVFVP-DSKPLDELLREMQRDRNHM
MSMEG_4495|M.smegmatis_MC2_155 KDLVQQTYYSTNGGRDTTVAQVMRPAVFVP-DSKPLDELLSEMQRDRNHM
MAB_1670|M.abscessus_ATCC_1997 KDLVQQTYYSVNGGRDVTVAQVMRPAVFVP-DSKPLDELLREMQQHRKHM
Mb2387c|M.bovis_AF2122/97 KDLVEQTFCSTNGGRETTVARVMRPAVFVP-DSKPLDALLREMQRDRNHM
Rv2366c|M.tuberculosis_H37Rv KDLVEQTFCSTNGGRETTVARVMRPAVFVP-DSKPLDALLREMQRDRNHM
MMAR_3676|M.marinum_M KDLVRQTFCAPDQGRKIDVSDLMRPAVFVP-DSKPLDALLREMQHDRNHM
MAV_2028|M.avium_104 KDLVQQALLPGGSGRATPVSQVMRPAVFVP-DSKPLDALLREMQRDRNHM
MUL_3669|M.ulcerans_Agy99 RDVVRQLHTHGASVLTRPVSKIMTSAVATCTKSDTVDSISVLMTQNRVRH
:*:*.: *: :* .. . .*..:* : * :.* :
Mflv_2708|M.gilvum_PYR-GCK VLLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGELSYRVS
Mvan_3830|M.vanbaalenii_PYR-1 VLLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPVEDLGDQQYRVS
TH_1056|M.thermoresistible__bu ALLVDEYGAIAGLVTIEDVLEEIVGEIADEYDTDEVAPIEDLGDNRYRVS
MSMEG_4495|M.smegmatis_MC2_155 ALLVDEYGATAGLVTIEDVLEEIVGEIADEYDTDEVAPVDEIDDHIYRVS
MAB_1670|M.abscessus_ATCC_1997 ALLVDEYGAIAGLVTIEDVLEEIVGEIADEYDHDEVAPVEELGDKMFRVS
Mb2387c|M.bovis_AF2122/97 ALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVS
Rv2366c|M.tuberculosis_H37Rv ALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPVEDLGDKRFRVS
MMAR_3676|M.marinum_M ALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDEAETAPVEALGDKRFRVS
MAV_2028|M.avium_104 ALLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVS
MUL_3669|M.ulcerans_Agy99 VPVLDGQ-KLIGIVSIGDVVKSRMGELEAEQEQLQSYITQG---------
. ::* *:*:* **::. :**: * : : :
Mflv_2708|M.gilvum_PYR-GCK ARLPIEDLSELYGIDFDEGLDVDTVGGLVALELGRVPLPGAEVEWDGLRL
Mvan_3830|M.vanbaalenii_PYR-1 ARLSIEDLGELYGIDFEEDLDVDTVGGLVALELGRVPLPGAEVTWDGLRL
TH_1056|M.thermoresistible__bu ARLPIEDLGELYGREFDGDLDVDTVGGLVALELGRVPLPGAEVTWDGLRL
MSMEG_4495|M.smegmatis_MC2_155 ARLPIEDLAELYELELDEDLDVDTVGGLMAFELGRVPLPGAEVTWEGLRL
MAB_1670|M.abscessus_ATCC_1997 ARLPIEDLGELYGIEFDEDLDVETVGGLLALDLGRVPLPGAKVASHGLLL
Mb2387c|M.bovis_AF2122/97 ARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRL
Rv2366c|M.tuberculosis_H37Rv ARLPIEDVGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRL
MMAR_3676|M.marinum_M ARLPIEDVGELYGIEFDGDLDVDTVGGLLALELGRVPLPGAEVIFHGLRL
MAV_2028|M.avium_104 ARLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRL
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2708|M.gilvum_PYR-GCK RAEGGPDPRGRVRIGTVLVSPVEPP--------NDDDEGHE---------
Mvan_3830|M.vanbaalenii_PYR-1 RAEGGPDPRGRVRIGTVLVSPVEPA--------PDTAEGHE---------
TH_1056|M.thermoresistible__bu RAEGGPDHRGRVRIGTVLVSPVEPED-------ADDTEDRDGADD-----
MSMEG_4495|M.smegmatis_MC2_155 RAEGGPDHRGRVRINTVLVCPTEPVEPELHTVPGDENSGRTRRGDRGDRS
MAB_1670|M.abscessus_ATCC_1997 QAEGGPDARGRVRIGTILVQPDPDAES------DEKAEERDE--------
Mb2387c|M.bovis_AF2122/97 HAEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG----
Rv2366c|M.tuberculosis_H37Rv HAEGGTDHRGRVRIGTVLLSPAE----------PDGADDEEADHPG----
MMAR_3676|M.marinum_M RAEGGPDHRGRVRIGTVLVSPMETEE-------TDGAGDGAAETGADG--
MAV_2028|M.avium_104 HAEGGTDHRGRVRVGTVLLSPVE----------SDGSPDGEEPEHHD---
MUL_3669|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2708|M.gilvum_PYR-GCK -------
Mvan_3830|M.vanbaalenii_PYR-1 -------
TH_1056|M.thermoresistible__bu -------
MSMEG_4495|M.smegmatis_MC2_155 RGGEKDE
MAB_1670|M.abscessus_ATCC_1997 -------
Mb2387c|M.bovis_AF2122/97 -------
Rv2366c|M.tuberculosis_H37Rv -------
MMAR_3676|M.marinum_M -------
MAV_2028|M.avium_104 -------
MUL_3669|M.ulcerans_Agy99 -------