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M. smegmatis MC2 155 MSMEG_4427 (-)

annotation: transmembrane efflux pump
coordinates: 4507529 - 4508977
length: 482

MVSLRSVAPTHRAMVVAVTVSMVAFLDSTVINLALTAIEHDLGGGLPLQQWIVDGYLLTMAAAILPGGSI
SDLFGRVPVMRFGLVVFGAGSVLGAVAASAEVLIAARLIQGLGAAFLVPGSLALINTVFDKAHQSAAIGV
WTAWTGTAFALGPLLGGLCVDLLGWRWVFVLSAIPMAAGYALTFWLCPVSGRVAHARIDIVGVVLSSVGL
AAIVFALIESQRRGWTDLVVGTPAVLGAAALSGFVSRQRRSGHPLLPLSLFTARNFAAVNLVTVFVYSAL
TLGSLAVVLYAQEIGGYSATSAGLATLPIPVMSFVLARRVGRIAARTGPRMFLIAGPALSGLGMILIRLK
DDGFHAMTDLLPGMTVLALGLVLTVTPLTSVALASVPTEHSGLASAVNNAAARLAALVSIGSMGLITVGA
SAAGFADVLKVSAALFVLGSLCAALWISDSLDGYGPVPCDLATSCRDRPGVQPALAEQSPPQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4427--100% (482)transmembrane efflux pump
M. smegmatis MC2 155MSMEG_5046-1e-5533.50% (391) drug transporter
M. smegmatis MC2 155MSMEG_5670-9e-5431.31% (428) efflux membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2361c-1e-5332.91% (395) integral membrane transport protein
M. gilvum PYR-GCKMflv_0301-7e-7739.00% (459) EmrB/QacA family drug resistance transporter
M. tuberculosis H37RvRv3239c-4e-5333.73% (424) transmembrane transport protein
M. leprae Br4923MLBr_01562-1e-3929.04% (396) putative transmembrane efflux protein
M. abscessus ATCC 19977MAB_0945-1e-5231.28% (406) EmrB/QacA family drug resistance transporter
M. marinum MMMAR_1146-5e-5832.68% (410) integral membrane transport protein
M. avium 104MAV_1387-2e-5433.50% (391) drug transporter
M. thermoresistible (build 8)TH_3965-3e-5532.78% (418) PUTATIVE drug transporter
M. ulcerans Agy99MUL_0911-4e-5832.63% (429) integral membrane transport protein
M. vanbaalenii PYR-1Mvan_4474-1e-5732.83% (399) EmrB/QacA family drug resistance transporter

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------MVSLRS
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------MTGLRM
TH_3965|M.thermoresistible__bu      ----------------------------VTSVDAGRSTMSEVFTAYAPRS
Mvan_4474|M.vanbaalenii_PYR-1       -----------------------------------------MFETVTARV
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------MRIQPV
MUL_0911|M.ulcerans_Agy99           --------------------------------------------MRIQPV
MAB_0945|M.abscessus_ATCC_1997      ------------------------------------------MEAAVGAL
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        ---------------------------------MHISLHGGKGFANLTRR
MLBr_01562|M.leprae_Br4923          MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      -VAPTHRAMVVAVTVSMVAFLDSTVINLALTAIEHDLG-GGLPLQQWIVD
Mflv_0301|M.gilvum_PYR-GCK          GTAAGRWVLLATVLGSGIVMVDATVVNVALPHIAADLG-GGFGDLQWVVN
TH_3965|M.thermoresistible__bu      AAANPWHALWAMLIGFFMILVDATIVPVANLEIMADLG-ADYTAVIWVTS
Mvan_4474|M.vanbaalenii_PYR-1       RGADPWPALWALLIGFFMILVDATIVPVANPAIMAQLG-ADYDAVIWVTS
MAV_1387|M.avium_104                -----------MMIGFFMIMVDSTIVAIANPTIMADLH-IGYDTVVWVTS
MMAR_1146|M.marinum_M               FRDHPIPALAVICLSVFVISVDATIVNVALPTLSRQLG-ADTAQLQWIVD
MUL_0911|M.ulcerans_Agy99           FRDHPILALAVICLSVFVISVDATIVNVALPTLSRELG-ADTAQLQWIVD
MAB_0945|M.abscessus_ATCC_1997      SERRKIVILGSCCLSLLIVSMDSTIVNVALPTIRADFG-ATTSQLQWVID
Mb2361c|M.bovis_AF2122/97           MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFA-VGEDGLQWVVA
Rv3239c|M.tuberculosis_H37Rv        RRPSSASVLLVAGFGAFLAFLDSTIVNIAFPDIQRSFPSYDIGSLSWILN
MLBr_01562|M.leprae_Br4923          PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELS-LSDAGRSWGIT
                                                     :  :*: :  :*   :  .:         *   

MSMEG_4427|M.smegmatis_MC2_155      GYLLTMAAAILPGGSISDLFGRVPVMRFGLVVFGAGSVLGAVAASAEVLI
Mflv_0301|M.gilvum_PYR-GCK          AYTLTLASLILLGGSLGDHFGRRKVFVLGVVWFALASIACGLAPSIEVLI
TH_3965|M.thermoresistible__bu      AYLLAYAVPLLIAGRLGDRFGPRTMYLIGLAIFTAASLWCGLAGTIGMLI
Mvan_4474|M.vanbaalenii_PYR-1       AYLLAYAVPLLVSGRLGDRYGPKTVYLVGLAVFTAASLWCGLSDSIGMLV
MAV_1387|M.avium_104                AYLLGYAVVLLVAGRLGDRFGTKNLYLIGLAVFTVASVWCGLAGSAAMLI
MMAR_1146|M.marinum_M               AYTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADTLI
MUL_0911|M.ulcerans_Agy99           AYTLVMSGLLLSAGSLSDRYGRRGWLSAGLILFALTSALAAQVNSADTLV
MAB_0945|M.abscessus_ATCC_1997      IYTLGLASLLMLSGAAGDRLGRRKVFHLGLSIFAIGSLLCSVAPTVGLLI
Mb2361c|M.bovis_AF2122/97           SYSLGMAVFIMSAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLT
Rv3239c|M.tuberculosis_H37Rv        GYNIVFAAFMVAAGRLADLLGRRRTFLSGVLVFTIASGLCAVAGSVEQLV
MLBr_01562|M.leprae_Br4923          AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLV
                                     * :  .  :: ..  .*  *       *:  *   *   .       * 

MSMEG_4427|M.smegmatis_MC2_155      AARLIQGLGAAFLVPGSLALINTVFDK-AHQSAAIGVWTAWTGTAFALGP
Mflv_0301|M.gilvum_PYR-GCK          VARALQGVGGALLTPGSLALISAAFAS-GDRGAAVGAWSGLGGIAGAIGP
TH_3965|M.thermoresistible__bu      AARVLQGLGAALLTPQTLSMITRIFPA-DRRGVPMGVWGATAGVATLIGP
Mvan_4474|M.vanbaalenii_PYR-1       AARVLQGVGAALLTPQTLTVITRTFPA-HNRGVAMSVWGATAGVATLAGP
MAV_1387|M.avium_104                AARVVQGVGAGVMTPQTLSTITRIFPA-ERRGVAVSVWSATAGAASLAGP
MMAR_1146|M.marinum_M               AARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGVAVGP
MUL_0911|M.ulcerans_Agy99           AARAAMGVGAAVIFPTTLGLITNIFTDPVPRAKAIGLWTAMVGVGVAVGP
MAB_0945|M.abscessus_ATCC_1997      AARLLQAVGGSMLNPVALSIISQVFTGRVERARALGFWGAVVGISMALGP
Mb2361c|M.bovis_AF2122/97           TARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIGIWTAIASIGTTTGP
Rv3239c|M.tuberculosis_H37Rv        AFRVLQGIGAAILVPASLALVVEGFDA-ARRAHAIGLWGAAAAIAAGLGP
MLBr_01562|M.leprae_Br4923          IARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGL
                                      *   .:*..      *  :   *     :  . . : .  . .   * 

MSMEG_4427|M.smegmatis_MC2_155      LLGGLCVDLLGWRWVFVLSAIPMAAGYALTFWLCPVSG-RVAHARIDIVG
Mflv_0301|M.gilvum_PYR-GCK          FLGGALVEWN-WRAAFLINVPLAAFVIAVTLLRVPESRDPSASRRLDVGG
TH_3965|M.thermoresistible__bu      LAGGVLVDGLGWQWIFIVNVPIGIAGLVLGARLMPRLP-RQ-DQGFDVLG
Mvan_4474|M.vanbaalenii_PYR-1       LAGGVLVDSLGWQWIFIVNLPVGVLGFALAVWLVPSLP-TARAQRFDLPG
MAV_1387|M.avium_104                LAGGVLVDGLGWQWIFFVNVPIGVLGLVLAYWLVPVLP-TQ-SHRFDLVG
MMAR_1146|M.marinum_M               ITGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSR-DPAAPRVDVPG
MUL_0911|M.ulcerans_Agy99           ITGGWLLEHFSWGSIFLVNVPIAVAAMAGAILFVPTSR-DPAAPRVDVPG
MAB_0945|M.abscessus_ATCC_1997      IVGGLLIQWVGWRAVFWINLPVCVLAFVLTAVFVPETK-SATMRDIDPVG
Mb2361c|M.bovis_AF2122/97           TLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESC-NERARRFDLSG
Rv3239c|M.tuberculosis_H37Rv        PIGGLLVEWAGWRWVLLVNVPLGIVAAIATKRMLVESRASGRRRMPDLRG
MLBr_01562|M.leprae_Br4923          VVGGALTEVS-WRLAFLVNVPIGLVMIYLARTALHETH--KERMKLDAAG
                                      **   :   *   : :.                           *  *

MSMEG_4427|M.smegmatis_MC2_155      VVLSSVGLAAIVFALIESQRRGWTDLVVGTPAVLGAAALSGFVSRQRRSG
Mflv_0301|M.gilvum_PYR-GCK          AVLTVVGLGALTFGLTELGNRGASPAAVVS-VGGGLVALVVFVLVEQRSS
TH_3965|M.thermoresistible__bu      MVLSAVGLFLIVFALQEAQTHRWAPWIWGTLAGGAGVMAMFVIWQSANRR
Mvan_4474|M.vanbaalenii_PYR-1       VVLSGVALFLIVFALQEGQSHDWAPWIWATIGIGIAVMAAFLYWQSVNTG
MAV_1387|M.avium_104                VGLSGVGMLLIVFGLQQGQAAHWQPWIWALIVAGVGFVTVFVFWQSVNVR
MMAR_1146|M.marinum_M               LMLSAVGITALVYTIIEAPNWGWTSTRASGGFIAAAIVLVGFALWERRSS
MUL_0911|M.ulcerans_Agy99           LMLSAVGITALVYTIIEAPNWGWTSTRASGGFIAAAIVLVGFALWERRSS
MAB_0945|M.abscessus_ATCC_1997      QALAVLFLFGIVFALIEGPSLGWATPGLIVVLAVALAAFAVFLRYESRRR
Mb2361c|M.bovis_AF2122/97           QLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSS
Rv3239c|M.tuberculosis_H37Rv        ALLLAVTLGLVTLGLVKGPDWGWLSVATVGSFLASVLTSVGFVHSSRSHP
MLBr_01562|M.leprae_Br4923          AILATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAE
                                      *  :     .  .                          .   .    

MSMEG_4427|M.smegmatis_MC2_155      HPLLPLSLFTARNFAAVNLVTVFVYSALTLGSLAVVLYAQEIGGYSATSA
Mflv_0301|M.gilvum_PYR-GCK          HPLMSPKLFADRNFGVANAVTLLIYGALGAVFLLLVLQLQTVSGFSPVAA
TH_3965|M.thermoresistible__bu      HPLVPLQIFADRNFMLANVGVATIGFVVTAMVLPAMFFAQAVCGLSPTGS
Mvan_4474|M.vanbaalenii_PYR-1       EPLIPLIIFGDRNFSMSNLGVATIGFVATGMILPLMFYAQSVCGLTPTQA
MAV_1387|M.avium_104                EPLIPLVIFSDRDFSLCNIGVAIISFAATAMMLPLTFYAQAVCGLSPTRS
MMAR_1146|M.marinum_M               HPMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQFIKDYTALQT
MUL_0911|M.ulcerans_Agy99           HPMLDVSVFANRRFSGGSLAVTAGFLTLFGFIFVITQYFQFIKDYTALQT
MAB_0945|M.abscessus_ATCC_1997      HPFIDLRFFRSIPFASATLTAICACMAWSAFLFTMSLYLQGQRHFSAMHT
Mb2361c|M.bovis_AF2122/97           NPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVT
Rv3239c|M.tuberculosis_H37Rv        APLVEPALLRSRSFVAGNLLTLVAAAGFYCYGLTHVLYLNYVWHYSLLKA
MLBr_01562|M.leprae_Br4923          NPVVPFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYSALRA
                                     *.:   .:                       .      :     :   :

MSMEG_4427|M.smegmatis_MC2_155      GLATLPIPVMSFVLARRVGRIAARTGPRMFLIAGPALSGLGMILIRLKDD
Mflv_0301|M.gilvum_PYR-GCK          GTALLPFTIVMLLFSSRAGALSGRIGPRLPMTVGPVLAGLGLLLMLRIGE
TH_3965|M.thermoresistible__bu      ALLIAPMAVASGVLAPMAGRIVDRSHPTPVVGFGFSVVAVGLTWLAVEMA
Mvan_4474|M.vanbaalenii_PYR-1       ALLTAPMAVATGVLAPLVGKLVDRSHPRPVVGFGFALMAIGLTWLSIEMT
MAV_1387|M.avium_104                ALLIAPMAIANGVFAPFVGKIVDRYHPRPVLGFGFSLLAIALTWLTFEMS
MMAR_1146|M.marinum_M               GVRLLPVALSIALAAILGPRLVERVGTTAVVAAGLAVFAAALAWAST-AD
MUL_0911|M.ulcerans_Agy99           GVRLLPVAFSIALAAILGPRLVERVGTTAVVAAGLAVFAAALAWAST-AD
MAB_0945|M.abscessus_ATCC_1997      GLIYLPIAVGALVFSPISGRMVGRFGARPSLLAAGTLFLTASLLLTR-VS
Mb2361c|M.bovis_AF2122/97           GLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIF-SE
Rv3239c|M.tuberculosis_H37Rv        GFAIAPAAVVAAVVAAALGRVAGRHGHRVIVLVGALVWAGSLVWYLQRVG
MLBr_01562|M.leprae_Br4923          GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN
                                    .    *      :       :  *         .  :   .         

MSMEG_4427|M.smegmatis_MC2_155      GFHAMTDLLPG-MTVLALGLVLTVTPLTSVALASVP-TEHSGLASAVNNA
Mflv_0301|M.gilvum_PYR-GCK          DASWVFDVAPA-ALVFGAGMVLVVAPLTATVLDAAP-EHMAGSASGVNNA
TH_3965|M.thermoresistible__bu      PTTPIWRLVLP-FVAVGVGMAFIWSPLATTATRQLP-LHLSGAGSGVYNT
Mvan_4474|M.vanbaalenii_PYR-1       PSTPIWRLVVP-LTAMGVAMAFIWSPLAATATRNLP-PQLAGAGSGVYNT
MAV_1387|M.avium_104                PATPIWRLVLP-FFAMGVGMAFVWSPLTATATRNLS-AQLAGAGSAVYNS
MMAR_1146|M.marinum_M               ATTPYTQIALQ-MLLLGGGLGLTTAPATEAIMGSLP-ADRAGVGSAVNDT
MUL_0911|M.ulcerans_Agy99           ATTPYTQITLQ-MLLLGGGLGLTTAPATEAIMGSLP-ADRAGVGSAVNDT
MAB_0945|M.abscessus_ATCC_1997      EATPIWELLVT-FAIFGAGFAMVNAPITNAAVSGMP-LDRAGAASAVTST
Mb2361c|M.bovis_AF2122/97           HRS-SALVLVG-LGLCGSGVALCLTPITTVAMTAVP-AERAGMASGIMSA
Rv3239c|M.tuberculosis_H37Rv        SEPDFLRVWLPGQLLQGIGVGATLPVLSSAALAEVAKGGSYATSSAVVST
MLBr_01562|M.leprae_Br4923          RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVG-FDRIGPVSAIALM
                                                    . ..       :             .  *.:   

MSMEG_4427|M.smegmatis_MC2_155      AARLAALVSIGSMG----------------------------LITVGASA
Mflv_0301|M.gilvum_PYR-GCK          VARAGGLLAVAVLPGVAGISG-------------------NDYADPAAFS
TH_3965|M.thermoresistible__bu      TRQIGSVLGSAGMAAFLTGRLSAELPFGATAVPAGEQTRVLPEFLHAPYA
Mvan_4474|M.vanbaalenii_PYR-1       TRQVGSVLGSAAMAALLASQLSAKIP-GEAPVPVEGQAGQLPAFLHAPFA
MAV_1387|M.avium_104                VRQLGAVLGSAGMAAFMTWRIGAEMPGQPGGGGEDSAGPVLPEFLRGPFA
MMAR_1146|M.marinum_M               TRELGGTLGVAIAGSVFASVYSGQLGSASTLATLPSDVRSAMKGSMAVAH
MUL_0911|M.ulcerans_Agy99           TRELGGTLGVAIAGSVFASVYSGQLGSASALATLPSDVRSAMKGSMAVAH
MAB_0945|M.abscessus_ATCC_1997      SRQVGVSIGVALCG------------------SIGTPALWFMCAGLGLLI
Mb2361c|M.bovis_AF2122/97           QRAIGSTIGFAVLGSVLAAWLSATLEPHLERAVPDPVQRHVLAEIIIDSA
Rv3239c|M.tuberculosis_H37Rv        TRQLGAVLGVAVMVILIGKPEHGTAEEALRRGWAMAAICFIAVAVAAAVL
MLBr_01562|M.leprae_Br4923          LQSLGGPLVLAVIQAVITSR----------------------TLYLGGTT
                                        .  :  .                                       

MSMEG_4427|M.smegmatis_MC2_155      AGFADVLKVSAALFVLGSLCAALWISD-----------------------
Mflv_0301|M.gilvum_PYR-GCK          AGFHTAVVISAVLMVAAAVLAAIGIRR-----------------------
TH_3965|M.thermoresistible__bu      AAMAQSMLLPAFVALFGVLAAIFLAGI--VLSTP--------------QP
Mvan_4474|M.vanbaalenii_PYR-1       AAMSQAMLLPAFVALFGVIAALFLVGLGDRLPAPPRRPQETAEPVPAFDP
MAV_1387|M.avium_104                AAMSQSVLLPAFIALFGIVAALFLVGFRPWAHRDGG--------TDAFGP
MMAR_1146|M.marinum_M               KVIDQLPAGPAAGVRDAVNHAFLDGLQ-----------------------
MUL_0911|M.ulcerans_Agy99           KVIDQLPAGPAAGVRDAVNHAFLDGLQ-----------------------
MAB_0945|M.abscessus_ATCC_1997      ATLGIVSTSPAAVRSAQRLAPLIEGTT-----------------------
Mb2361c|M.bovis_AF2122/97           NPRAHVGGIVPRRHIEHRDPVAIAEED-----------------------
Rv3239c|M.tuberculosis_H37Rv        GRTNRNPVQMPAPEPAIAPRLEPPIPQPAAAPIEHWAAGDADPLGNLPLF
MLBr_01562|M.leprae_Br4923          GPVKFMNDAQLRALDHGYTYGLLWVAG-----------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      DAD-AQYLDEHDD---YLVIELAR--------------------------
Mvan_4474|M.vanbaalenii_PYR-1       DDE-LYWADGEDE---YVEYEVPWDDGAEPRRPAQEADTVDAAADTDVLD
MAV_1387|M.avium_104                DDYGGDYHDDYDDDDAYVELILVREPEPEAQQRAGQPRRPQPTPAPPADV
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        AGLDAATLAQLGEHVEDVELEAGCYLFHEGDPSDSLYVIRTGRVQVLQDS
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      ----------------SLDGYG-PVPCDLATSCRDRPGVQPALAEQSPPQ
Mflv_0301|M.gilvum_PYR-GCK          ----------------APARSDERMAVENCTHC-AITGLPAHPAAETR--
TH_3965|M.thermoresistible__bu      ----------------PDPNPRTDIAVTAVIP-----ALRPTLRPTLRPS
Mvan_4474|M.vanbaalenii_PYR-1       PVTEPMHDGGGYPA--PESAPRRDHADPTSHPDREWRSILDQLLDPPKPS
MAV_1387|M.avium_104                RRRDPVESRRSVLDERPAQVQPIGFAHNGSHVDGGKRLRQVAVRRAPKPG
MMAR_1146|M.marinum_M               ----------------VATLVCAGIALAAAIVVGWLLPARAGQPTPAQTE
MUL_0911|M.ulcerans_Agy99           ----------------VATLVCAGIALAAAIVVGWLLPARAGQPTPAQTE
MAB_0945|M.abscessus_ATCC_1997      ----------------AREMSRVG--------------------------
Mb2361c|M.bovis_AF2122/97           ----------------FIEGIRVALLVATATLAVVFLAGWRWFPRDVQTA
Rv3239c|M.tuberculosis_H37Rv        IVLKELGRGEVLGELGLLIDAPRSATVRALRDTKLVRLTKAQFDEIADHG
MLBr_01562|M.leprae_Br4923          ------------------AVVIVGVAALFIGYTPEQVAYAQEVKEAVDAG
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      L--------------GPPG----------GPVVQP--NNTAALR------
Mvan_4474|M.vanbaalenii_PYR-1       D--------------DPTGQGRN------GFHVTPSEDGRGASRGRHSLD
MAV_1387|M.avium_104                PPADRFTRPPRRHHPGPAGHHLGEGESLRGQHHRPDPDDDPTGYGRHSSG
MMAR_1146|M.marinum_M               PALAQA--------------------------------------------
MUL_0911|M.ulcerans_Agy99           PALAQV--------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           GSDAKREAAYSDDRRVRG--------------------------------
Rv3239c|M.tuberculosis_H37Rv        ALAALVKVLATRLREAPPPATDSTSPEVVVSVIGVSGDAPVPAVAAGLLT
MLBr_01562|M.leprae_Br4923          EL------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                N-------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        ALSARLRAVDPGRVDRDGLDRAERVADKVVLHAAVEDAGWRDFCLRVADR
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        IVLVAGDPNPQAARLPARARGADLVLAGPAASREHRRQWEELITPRSVHV
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        VHYRRILENVRPLAARIAGRSIGLVLGGGGARGFAHLGVLDELERVGVTI
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        DRFAGTSMGAVIAVFGACGMDAATADAYAYEYFIRHNPLSDYAFPVRGLV
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        RGRRTLTLLEAAFGDRLVEELPKEFRCVSVDLLARRPVVHRRGRLVDVIG
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        CSLRLPGIYPPQVYNGRLHVDGGVLDNLPVSTRASPDGPLIAVSIGLGGG
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_1387|M.avium_104                --------------------------------------------------
MMAR_1146|M.marinum_M               --------------------------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------------------------
Rv3239c|M.tuberculosis_H37Rv        GPGSARQDGSPKVPGIGDTLMRTMTIGSQRGADAALSLAQVVIRPDTGAV
MLBr_01562|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MSMEG_4427|M.smegmatis_MC2_155      --------------------------------
Mflv_0301|M.gilvum_PYR-GCK          --------------------------------
TH_3965|M.thermoresistible__bu      --------------------------------
Mvan_4474|M.vanbaalenii_PYR-1       --------------------------------
MAV_1387|M.avium_104                --------------------------------
MMAR_1146|M.marinum_M               --------------------------------
MUL_0911|M.ulcerans_Agy99           --------------------------------
MAB_0945|M.abscessus_ATCC_1997      --------------------------------
Mb2361c|M.bovis_AF2122/97           --------------------------------
Rv3239c|M.tuberculosis_H37Rv        GLLEFHQIDAAREAGRVAAREAMPHIMALLNR
MLBr_01562|M.leprae_Br4923          --------------------------------