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NVIGITLLPRGRIMSHGPVSDDTPSIFGDDDQAASSGRTAVRIAAVAALGGLLFGYDSAVINGAVDSIQE DFGIGNYALGLAVASALLGAAAGALSAGRIADRIGRIAVMKIAAVLFFISAFGTGFAPETVTLVVFRIVG GIGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAIVLGIFTSFVVNWLLQWAAGGPNEVLAMGLDAWRWM FLAMAVPAVLYGALAFTIPESPRYLVATHKIPEARRVLSMLLGQKNLEITITRIRDTLEREDKPSWRDLK KPTGGIYGIVWVGLGLSIFQQFVGINVIFYYSNVLWQAVGFSADQSAIYTVITSVVNVLTTLIAIALIDK IGRKPLLLIGSSGMAVTLATMAVIFANATVKPDGTPDLPGASGLIALIAANLFVVAFGMSWGPVVWVLLG EMFPNRFRAAALGLAAAGQWAANWLITVSFPELRNHLGLAYGFYALCAVLSFLFVSKWVEETRGKNLEDM HAEALGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4182 | - | - | 100% (498) | arabinose-proton symporter |
| M. smegmatis MC2 155 | MSMEG_2001 | - | 3e-63 | 57.00% (207) | sugar transporter |
| M. smegmatis MC2 155 | MSMEG_2004 | - | 3e-54 | 53.05% (213) | arabinose-proton symporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 4e-51 | 28.29% (463) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_3055 | - | 0.0 | 85.30% (483) | sugar transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 3e-50 | 28.08% (463) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | MLBr_01562 | - | 9e-10 | 33.61% (122) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_0692c | - | 0.0 | 70.50% (461) | sugar transporter |
| M. marinum M | MMAR_1191 | sugI | 2e-50 | 28.04% (453) | sugar-transport integral membrane protein SugI |
| M. avium 104 | MAV_4306 | - | 4e-53 | 29.55% (467) | transporter, major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_2640 | - | 1e-136 | 74.15% (325) | PUTATIVE sugar transporter |
| M. ulcerans Agy99 | MUL_1444 | sugI | 7e-51 | 28.04% (453) | sugar-transport integral membrane protein SugI |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 0.0 | 87.06% (479) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3364|M.bovis_AF2122/97 MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
Rv3331|M.tuberculosis_H37Rv MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
MMAR_1191|M.marinum_M -----------------------------------------------MQR
MUL_1444|M.ulcerans_Agy99 -----------------------------------------------MQR
MAV_4306|M.avium_104 -------------------------------------------MARGSRR
Mflv_3055|M.gilvum_PYR-GCK -----------------------MAGQGGPAGESPELY-EKGQDFSSGKT
Mvan_3472|M.vanbaalenii_PYR-1 -----------------------MAGQGGPVGDGPEIF-EQGQEFSSGKT
MSMEG_4182|M.smegmatis_MC2_155 ----------MNVIGITLLPRGRIMSHGPVSDDTPSIFGDDDQAASSGRT
TH_2640|M.thermoresistible__bu --------------------------------------------------
MAB_0692c|M.abscessus_ATCC_199 --------------------------------------MSEEDEFSSGHS
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb3364|M.bovis_AF2122/97 A----LLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTT
Rv3331|M.tuberculosis_H37Rv A----LLVGLTAASVGVLYGYDLSAIAGALLSLSEEFELTTREQELLTTT
MMAR_1191|M.marinum_M G----ILVALTAASVGLIYGYDLSIIAGAQLFITEEFGLSTHQQELLTTM
MUL_1444|M.ulcerans_Agy99 G----ILVALTAASVGLIYGYDLSIIAGAQLFITEEFGLSTHQQELLTTM
MAV_4306|M.avium_104 G----LLVGLTAASVGVIYGYDLSIIAGAQLFVTEDFGLSTRQQELLTTM
Mflv_3055|M.gilvum_PYR-GCK A----IRIASVAALGGLLFGYDSAVINGAVASIQEDFGIGNYALGLAVAS
Mvan_3472|M.vanbaalenii_PYR-1 A----VRIASVAALGGLLFGYDSAVINGAVDSIQEDFGIGNAELGFAVAS
MSMEG_4182|M.smegmatis_MC2_155 A----VRIAAVAALGGLLFGYDSAVINGAVDSIQEDFGIGNYALGLAVAS
TH_2640|M.thermoresistible__bu --------------------------------------------------
MAB_0692c|M.abscessus_ATCC_199 A----LRIASVAALGGLLFGYDSAVINGAVQAIQDAFAIRDAELGFAVAS
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVAIVALPKIQNELSLSDAGRSWGITA
Mb3364|M.bovis_AF2122/97 AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVV
Rv3331|M.tuberculosis_H37Rv AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATSVSVPMLVV
MMAR_1191|M.marinum_M VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGSLSVSLPMLLA
MUL_1444|M.ulcerans_Agy99 VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGALSVSLPMLLA
MAV_4306|M.avium_104 AVIGQIGGALFAGVLANAIGRRRSVLLILSGYAVFALLAAFSVGLPMLLT
Mflv_3055|M.gilvum_PYR-GCK ALLGAAVGALSAGRIADRIGRIAVMKIAAVLFLLSAFGTAFAPETITLVI
Mvan_3472|M.vanbaalenii_PYR-1 ALLGAAAGAMTAGRIADRIGRIAVMKIAAVLFLVSAFGTGFAHEVWAVVL
MSMEG_4182|M.smegmatis_MC2_155 ALLGAAAGALSAGRIADRIGRIAVMKIAAVLFFISAFGTGFAPETVTLVV
TH_2640|M.thermoresistible__bu --------------------------------------------------
MAB_0692c|M.abscessus_ATCC_199 ALLGAAVGAMTAGRVADRIGRVAVMKIAAALFLLSAVGAGLAPNIELLVL
MLBr_01562|M.leprae_Br4923 YVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLVI
Mb3364|M.bovis_AF2122/97 ARLLLGVTIGLSVVVVPVYVAESAPAA-VRGSLVTAYQLATLSGIVVGYL
Rv3331|M.tuberculosis_H37Rv ARLLLGVTIGLSVVVVPVYVAESAPAA-VRGSLVTAYQLATLSGIVVGYL
MMAR_1191|M.marinum_M ARFLLGLAVGVSIVVVPVYVAESAPAA-VRGSLLTVYQLTTVSGLIVGYL
MUL_1444|M.ulcerans_Agy99 ARFLLGLAVGVSIVVVPVYVAESAPAA-VRGSLLTVYQLTTVSGLIVGYL
MAV_4306|M.avium_104 ARLLLGLTIGVTVVVVPVYVAESAPTA-VRGALLTAYQLAIVSGLIVGYL
Mflv_3055|M.gilvum_PYR-GCK GRIVGGVGVGVASVIAPAYIAETSPPG-IRGRLGSLQQLAIVSGIFASFA
Mvan_3472|M.vanbaalenii_PYR-1 FRIVGGIGVGVASVIAPAYIAETSPPG-IRGRLGSLQQLAIVSGIFASFA
MSMEG_4182|M.smegmatis_MC2_155 FRIVGGIGVGVASVIAPAYIAETSPPG-IRGRLGSLQQLAIVLGIFTSFV
TH_2640|M.thermoresistible__bu --------------------------------------LAIVSGIFLSLL
MAB_0692c|M.abscessus_ATCC_199 FRVIGGVGVGVASLIAPAYIAETSPSR-IRGRLGSLQQLAIVTGIFLSLT
MLBr_01562|M.leprae_Br4923 ARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGLV
* . .
Mb3364|M.bovis_AF2122/97 VGYLLAGSHG------------WRAMFGLAAAPATLLLPLLWRMP-----
Rv3331|M.tuberculosis_H37Rv VGYLLAGSHG------------WRAMFGLAAAPATLLLPLLWRMP-----
MMAR_1191|M.marinum_M TGYLLAGTHS------------WRWMLGLATVPAMLLLPLLIRMP-----
MUL_1444|M.ulcerans_Agy99 TGYLLAGTHS------------WRWMLGLATVPAMLLLPLLIRMP-----
MAV_4306|M.avium_104 SGYLLAGTHS------------WRWMLGLACVPAVLLLPLVFRMP-----
Mflv_3055|M.gilvum_PYR-GCK VNYLLQWLAGGPNEPLWLGMDAWRWMFLAMAVPAVVYGGLAFTIP-----
Mvan_3472|M.vanbaalenii_PYR-1 VNWLLQWAAGGPNEPLWFGLDAWRWMFLAMALPAVLYGVLAFTIP-----
MSMEG_4182|M.smegmatis_MC2_155 VNWLLQWAAGGPNEVLAMGLDAWRWMFLAMAVPAVLYGALAFTIP-----
TH_2640|M.thermoresistible__bu IDGILAALAGGSREELWLNMEAWRWMFLMMAVPAVLYGALTFTIP-----
MAB_0692c|M.abscessus_ATCC_199 IDWLLAHLAGSSRDELWLGLPAWRWMFLAMALPALVYGTLAFTIP-----
MLBr_01562|M.leprae_Br4923 VGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAILA
. * : : .
Mb3364|M.bovis_AF2122/97 -DTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVDERGG----G
Rv3331|M.tuberculosis_H37Rv -DTARWYLLKGRIADARSALRRIQPEADIDAELADMAAAVDERGG----G
MMAR_1191|M.marinum_M -DTPRWYVMKGRIQEARAALLRVDPAADVEEELAEIGTALSEGSG----G
MUL_1444|M.ulcerans_Agy99 -DTPRWYVMKGRIQEARAALLRVDPAADVEEELAEIGTALSEGSG----G
MAV_4306|M.avium_104 -DTARWYLLKGRVDDARRALLRVEPAARVDDELAEIGRAVSEEAASLPAM
Mflv_3055|M.gilvum_PYR-GCK -ESPRYLVATHKIPEARRVLSMLLGQKNLEITITRIRETLEREDRP---S
Mvan_3472|M.vanbaalenii_PYR-1 -ESPRYLVASHKIPEARRVLSMLLGKKNLEITITRIRETLEREDKP---S
MSMEG_4182|M.smegmatis_MC2_155 -ESPRYLVATHKIPEARRVLSMLLGQKNLEITITRIRDTLEREDKP---S
TH_2640|M.thermoresistible__bu -ESPRYLVATHRVPEARRVLSRLLGAKNLEITINRIERSLRAEKPP---S
MAB_0692c|M.abscessus_ATCC_199 -ESPRYLVATHRIPEARTVLATLLGEKNLDITIGRIQETLDQSTAP---S
MLBr_01562|M.leprae_Br4923 TLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPVV
: : : : : : : : ::
Mb3364|M.bovis_AF2122/97 IGEMVRRP--YLRATLFVIALGFLVQITG-----INAIIYYSPRLFAAMG
Rv3331|M.tuberculosis_H37Rv IGEMVRRP--YLRATLFVIALGFLVQITG-----INAIIYYSPRLFAAMG
MMAR_1191|M.marinum_M VSEMLRPP--FLRATIFVITLGFLIQITG-----INAIIYYSPRIFEAMG
MUL_1444|M.ulcerans_Agy99 VSEMLRPP--FLRATIFVITLGFLIQITG-----INAIIYYSPRIFEAMG
MAV_4306|M.avium_104 LAEMVRSP--YRRATVFVVVLGFLIQITG-----INAIIYYSPRIFEAMG
Mflv_3055|M.gilvum_PYR-GCK WRDLKKPTGGIYGIVWVGLGLSIFQQFVG-----INVIFYYSNVLWQAVG
Mvan_3472|M.vanbaalenii_PYR-1 WRDMRKPTGGLYGIVWVGLGLSIFQQFVG-----INVIFYYSNVLWQAVG
MSMEG_4182|M.smegmatis_MC2_155 WRDLKKPTGGIYGIVWVGLGLSIFQQFVG-----INVIFYYSNVLWQAVG
TH_2640|M.thermoresistible__bu WSDLRKPTGGMYGIVWVGLGLSIFQQFVG-----INVIFYYSNVLWEAVG
MAB_0692c|M.abscessus_ATCC_199 WRDLRKPTGGLHAIVWIGVALAVFQQLVG-----INVIFYYSNVLWQAVG
MLBr_01562|M.leprae_Br4923 PFDLFRDRNRLVTFIAIFLAGGVIFSLTVSIGLYIQDILGYS-ALRAGIG
:: : . : ..: .:. *: *: ** : .:*
Mb3364|M.bovis_AF2122/97 FAGYFAMLALPAMVQVAGLAAVCASLFLVDR-LGRRPILLSGIATMITAD
Rv3331|M.tuberculosis_H37Rv FAGYFAMLALPAMVQVAGLAAVCASLFLVDR-LGRRPILLSGIATMITAD
MMAR_1191|M.marinum_M FTGDFALLGLPALVQIAGVAAVITSLLLVDR-VGRRPILLSGIAIMIVAD
MUL_1444|M.ulcerans_Agy99 FTGDFALLGLPALVQIAGVAAVITSLLLVDR-VGRRPILLSGIAIMIVAD
MAV_4306|M.avium_104 FTGNFALLALPALVQVAGLVAVGTALLLVDR-VGRRPILLCGTAMMIVAD
Mflv_3055|M.gilvum_PYR-GCK FS-ADESAVYTVITSVVNVLTTLIAIALIDK-IGRKPLLLIGSVGMAVTL
Mvan_3472|M.vanbaalenii_PYR-1 FS-ADESAVYTVITSVINVLTTLIAIALIDK-IGRKPLLLIGSSGMAVTL
MSMEG_4182|M.smegmatis_MC2_155 FS-ADQSAIYTVITSVVNVLTTLIAIALIDK-IGRKPLLLIGSSGMAVTL
TH_2640|M.thermoresistible__bu FD-ESQSFLITVITSVTNIVTTLIAIALIDK-IGRKPLLLIGSTGMAGTL
MAB_0692c|M.abscessus_ATCC_199 FG-ESSSFTITVITSITNIATTLVAIALIDR-VGRKPLLLIGSAGMAATL
MLBr_01562|M.leprae_Br4923 FIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMNRGV
* .. : : :. :* * *
Mb3364|M.bovis_AF2122/97 AVLITVFANDSD------------GGTGLVLGFAGVLLFIIGFN-FGFGS
Rv3331|M.tuberculosis_H37Rv AVLITVFANDSD------------GGTGLVLGFAGVLLFIIGFN-FGFGS
MMAR_1191|M.marinum_M VALMAVFAR---------------GQGAAILGFAGILLFIIGYT-MGFGS
MUL_1444|M.ulcerans_Agy99 VALMAVFAR---------------GQGAAILGFAGILLFIIGYT-MGFGS
MAV_4306|M.avium_104 VVLVAVFGR---------------GPGGVIAGFAGVLLFIFGYT-MGFGS
Mflv_3055|M.gilvum_PYR-GCK STMAFIFANAELIENEAGEMVPSLPGASGVIALIAANLFVVAFG-MSWGP
Mvan_3472|M.vanbaalenii_PYR-1 ITMAVIFANATVGADGN----PSLPGASGVIALIAANLFVVAFG-MSWGP
MSMEG_4182|M.smegmatis_MC2_155 ATMAVIFANATVKPDGT----PDLPGASGLIALIAANLFVVAFG-MSWGP
TH_2640|M.thermoresistible__bu GVMAVIFGTAPVIDGQ-----PQLGDVAGPVALVAANLFVVSFG-MSWGP
MAB_0692c|M.abscessus_ATCC_199 GTMAVIFGSATMVDGK-----PHLGPVAGPVALVAANLFVVAFG-MSWGP
MLBr_01562|M.leprae_Br4923 PYFPNLLAPIVVGG---------IGIGMAVVPLTLSAIAGVGFDRIGPVS
: ::. : : ..: :. .
Mb3364|M.bovis_AF2122/97 LVWVYAAESFPSRLRSMGSSLMLTSTLTANAIVAAFSLTMLRVLGGAGVF
Rv3331|M.tuberculosis_H37Rv LVWVYAAESFPSRLRSMGSSPMLTSTLTANAIVAAFSLTMLRVLGGAGVF
MMAR_1191|M.marinum_M LGWVYASESFPTRLRSIGSSTMLTANLIANAIVAGVFLTMLHSLGGSGAF
MUL_1444|M.ulcerans_Agy99 LGWVYASESFPTRLRSIGSSTMLTANLIANAIVAAVFLTMLHSLGGSGAF
MAV_4306|M.avium_104 LGWVYASESFPSRLRSIGSSTMLTSNLVANAIVAAVFLTLLHSLGGAGTF
Mflv_3055|M.gilvum_PYR-GCK VVWVLLGEMFPNRIRAAALGLAAAGQWTANWVITVSFPELRNFLG--AAY
Mvan_3472|M.vanbaalenii_PYR-1 VVWVLLGEMFPNRIRAAALGLAAAGQWAANWLITVTFPGLREHLG--LAY
MSMEG_4182|M.smegmatis_MC2_155 VVWVLLGEMFPNRFRAAALGLAAAGQWAANWLITVSFPELRNHLG--LAY
TH_2640|M.thermoresistible__bu VVWVLLGEMFPNRIRAAALGLAAAGQWTANWVITVTFPGLREHLG--PAY
MAB_0692c|M.abscessus_ATCC_199 VVWVLLGEIFPNRIRAAAMGLATAGNWAANWAVTVTFPALRDALG--IAY
MLBr_01562|M.leprae_Br4923 AIALMLQSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHG
: . . : . : . *
Mb3364|M.bovis_AF2122/97 AVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAADEP
Rv3331|M.tuberculosis_H37Rv AVFGTFAVVAFVVVYRFAPETKGRKLEEIRHFWENGGRWPAERSPAADEP
MMAR_1191|M.marinum_M AVFGVLALVAFGVVYRYAPETKGRQLEEIRHFWENGGRWPEKLTEAP---
MUL_1444|M.ulcerans_Agy99 AVFGVLALVAFGVVYRYAPETKGRQLEEIRHFWENGGRWPEKLTEAP---
MAV_4306|M.avium_104 AVFAVLAVVAFAFVHRYAPETKGRQLEDIRHFWENGGRWD----------
Mflv_3055|M.gilvum_PYR-GCK GFYALCAVLSGLFVWKWVRETKGVSLEDMHGEILHGDKSATG--------
Mvan_3472|M.vanbaalenii_PYR-1 GFYGLCAVLSGLFVWRWVMETKGVSLEDMHGEILHADKTATG--------
MSMEG_4182|M.smegmatis_MC2_155 GFYALCAVLSFLFVSKWVEETRGKNLEDMHAEALGH--------------
TH_2640|M.thermoresistible__bu GFYALCAVLSLLFVWRWVAETKGRTLEDMQPDVPGHDRASAPG-------
MAB_0692c|M.abscessus_ATCC_199 GCYALCAVLSLLFVARWVEETKGRALEDMDSAIS----------------
MLBr_01562|M.leprae_Br4923 YTYGLLWVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL------
:. : . .: . * *::