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VARGSRRGLLVGLTAASVGVIYGYDLSIIAGAQLFVTEDFGLSTRQQELLTTMAVIGQIGGALFAGVLAN AIGRRRSVLLILSGYAVFALLAAFSVGLPMLLTARLLLGLTIGVTVVVVPVYVAESAPTAVRGALLTAYQ LAIVSGLIVGYLSGYLLAGTHSWRWMLGLACVPAVLLLPLVFRMPDTARWYLLKGRVDDARRALLRVEPA ARVDDELAEIGRAVSEEAASLPAMLAEMVRSPYRRATVFVVVLGFLIQITGINAIIYYSPRIFEAMGFTG NFALLALPALVQVAGLVAVGTALLLVDRVGRRPILLCGTAMMIVADVVLVAVFGRGPGGVIAGFAGVLLF IFGYTMGFGSLGWVYASESFPSRLRSIGSSTMLTSNLVANAIVAAVFLTLLHSLGGAGTFAVFAVLAVVA FAFVHRYAPETKGRQLEDIRHFWENGGRWD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4306 | - | - | 100% (450) | transporter, major facilitator superfamily protein |
| M. avium 104 | MAV_4814 | - | 3e-52 | 30.80% (448) | metabolite/sugar transport protein |
| M. avium 104 | MAV_3053 | - | 4e-17 | 23.68% (397) | sugar transport protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3364 | sugI | 1e-176 | 69.69% (452) | sugar-transport integral membrane protein SugI |
| M. gilvum PYR-GCK | Mflv_3055 | - | 2e-51 | 29.91% (468) | sugar transporter |
| M. tuberculosis H37Rv | Rv3331 | sugI | 1e-176 | 69.69% (452) | sugar-transport integral membrane protein SugI |
| M. leprae Br4923 | MLBr_00556 | - | 7e-06 | 22.35% (170) | putative integral membrane drug transport protein |
| M. abscessus ATCC 19977 | MAB_0365c | - | 1e-142 | 58.54% (451) | sugar-transport integral membrane protein |
| M. marinum M | MMAR_1191 | sugI | 0.0 | 77.03% (444) | sugar-transport integral membrane protein SugI |
| M. smegmatis MC2 155 | MSMEG_5559 | - | 1e-56 | 31.66% (439) | metabolite/sugar transport protein |
| M. thermoresistible (build 8) | TH_2640 | - | 2e-35 | 31.48% (324) | PUTATIVE sugar transporter |
| M. ulcerans Agy99 | MUL_1444 | sugI | 0.0 | 77.48% (444) | sugar-transport integral membrane protein SugI |
| M. vanbaalenii PYR-1 | Mvan_3472 | - | 3e-51 | 29.48% (458) | sugar transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3055|M.gilvum_PYR-GCK ------------------------MAGQGGPAGESPELYEKGQDFSSGKT
Mvan_3472|M.vanbaalenii_PYR-1 ------------------------MAGQGGPVGDGPEIFEQGQEFSSGKT
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
Rv3331|M.tuberculosis_H37Rv MTTLWQPHRNDYSPIPGRGVHARRGARRPRPRGGRAERPGTGQLTRSGRR
MMAR_1191|M.marinum_M -----------------------------------------------MQR
MUL_1444|M.ulcerans_Agy99 -----------------------------------------------MQR
MAV_4306|M.avium_104 -------------------------------------------MARGSRR
MAB_0365c|M.abscessus_ATCC_199 -------------------------------------MSLITDLRSTSRL
MSMEG_5559|M.smegmatis_MC2_155 ----------------------------MSTDTQDSADARAKTPGQLTGA
MLBr_00556|M.leprae_Br4923 ---------------------------------------------MSTRA
Mflv_3055|M.gilvum_PYR-GCK AIRIASVAALGGLLFG-YDSAVINGAVASIQEDFGIGNYALG---LAVAS
Mvan_3472|M.vanbaalenii_PYR-1 AVRIASVAALGGLLFG-YDSAVINGAVDSIQEDFGIGNAELG---FAVAS
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 ALLVGLTAASVGVLYG-YDLSAIAGALLSLSEEFELTTREQE---LLTTT
Rv3331|M.tuberculosis_H37Rv ALLVGLTAASVGVLYG-YDLSAIAGALLSLSEEFELTTREQE---LLTTT
MMAR_1191|M.marinum_M GILVALTAASVGLIYG-YDLSIIAGAQLFITEEFGLSTHQQE---LLTTM
MUL_1444|M.ulcerans_Agy99 GILVALTAASVGLIYG-YDLSIIAGAQLFITEEFGLSTHQQE---LLTTM
MAV_4306|M.avium_104 GLLVGLTAASVGVIYG-YDLSIIAGAQLFVTEDFGLSTRQQE---LLTTM
MAB_0365c|M.abscessus_ATCC_199 GVMVAVTAAAVGVIYG-YDSSNIAGALLFLTEDLHLSTHDQQ---VAATA
MSMEG_5559|M.smegmatis_MC2_155 VVIVALVSAVSGMLYG-YDTGIISGALLQITKDFSIAEAWKQ---VIAAS
MLBr_00556|M.leprae_Br4923 GRRVAISAGSLAVLLGALDTYVVVTIMRDIMHDVGIPVNQMQRITWIVTM
Mflv_3055|M.gilvum_PYR-GCK ALLGAAVGALSAGRIADRIGRIAVMKIAAVLFLLSAFGTAFA---PETIT
Mvan_3472|M.vanbaalenii_PYR-1 ALLGAAAGAMTAGRIADRIGRIAVMKIAAVLFLVSAFGTGFA---HEVWA
TH_2640|M.thermoresistible__bu --------------------------------------------------
Mb3364|M.bovis_AF2122/97 AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATS---VSVPM
Rv3331|M.tuberculosis_H37Rv AVLGQIAGALGGGILANAIGRKKSVVLIVAGYAVFALLGATS---VSVPM
MMAR_1191|M.marinum_M VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGSLS---VSLPM
MUL_1444|M.ulcerans_Agy99 VVIGQIVGALGAGVLANAIGRKKSVVMLLVAYTMFAVLGALS---VSLPM
MAV_4306|M.avium_104 AVIGQIGGALFAGVLANAIGRRRSVLLILSGYAVFALLAAFS---VGLPM
MAB_0365c|M.abscessus_ATCC_199 VVIGEIFGALIGGPLSNKIGRKRSMVLVAATFGIFSLLSALA---VDLNT
MSMEG_5559|M.smegmatis_MC2_155 ILLGAVIGALVCSHLSQKRGRKGTLLMLAVVFVIGSLWCAIS---PNPVL
MLBr_00556|M.leprae_Br4923 YLLGYIAAMPLLSRASDRFGRKLLLQVSLAGFAIGSVMTALAGQFGDFHM
Mflv_3055|M.gilvum_PYR-GCK LVIGRIVGGVGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAIVSGIFAS
Mvan_3472|M.vanbaalenii_PYR-1 VVLFRIVGGIGVGVASVIAPAYIAETSPPGIRGRLGSLQQLAIVSGIFAS
TH_2640|M.thermoresistible__bu ----------------------------------------LAIVSGIFLS
Mb3364|M.bovis_AF2122/97 LVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSGIVVG
Rv3331|M.tuberculosis_H37Rv LVVARLLLGVTIGLSVVVVPVYVAESAPAAVRGSLVTAYQLATLSGIVVG
MMAR_1191|M.marinum_M LLAARFLLGLAVGVSIVVVPVYVAESAPAAVRGSLLTVYQLTTVSGLIVG
MUL_1444|M.ulcerans_Agy99 LLAARFLLGLAVGVSIVVVPVYVAESAPAAVRGSLLTVYQLTTVSGLIVG
MAV_4306|M.avium_104 LLTARLLLGLTIGVTVVVVPVYVAESAPTAVRGALLTAYQLAIVSGLIVG
MAB_0365c|M.abscessus_ATCC_199 LAAARFLLGLTVGVSVVVVPVFVAESSPTKIRGSMLVLYQLACVTGIIAG
MSMEG_5559|M.smegmatis_MC2_155 LSVGRLVLGFAVGGATQTAPMYVAELSPPKYRGRLVLCFQIAIGVGIVIA
MLBr_00556|M.leprae_Br4923 LIAGRTIQGVASGALLPITLALGADLWAQRNRAGVLGGIGAAQELGSVLG
: * . .
Mflv_3055|M.gilvum_PYR-GCK FAVNYLLQWLAGGPNEPLWLGMDAWRWMFLA-MAVPAVVYGGLAFTIPES
Mvan_3472|M.vanbaalenii_PYR-1 FAVNWLLQWAAGGPNEPLWFGLDAWRWMFLA-MALPAVLYGVLAFTIPES
TH_2640|M.thermoresistible__bu LLIDGILAALAGGSREELWLNMEAWRWMFLM-MAVPAVLYGALTFTIPES
Mb3364|M.bovis_AF2122/97 YLVGYLLAGSHG------------WRAMFGL-AAAPATLLLPLLWRMPDT
Rv3331|M.tuberculosis_H37Rv YLVGYLLAGSHG------------WRAMFGL-AAAPATLLLPLLWRMPDT
MMAR_1191|M.marinum_M YLTGYLLAGTHS------------WRWMLGL-ATVPAMLLLPLLIRMPDT
MUL_1444|M.ulcerans_Agy99 YLTGYLLAGTHS------------WRWMLGL-ATVPAMLLLPLLIRMPDT
MAV_4306|M.avium_104 YLSGYLLAGTHS------------WRWMLGL-ACVPAVLLLPLVFRMPDT
MAB_0365c|M.abscessus_ATCC_199 YLIAWALSSTGS------------WRLMLGL-AAVPAALVLIALLKLPDT
MSMEG_5559|M.smegmatis_MC2_155 TIVG--ASEHIP------------WRWSIGA-AAVPAAIMLVLLLRLPES
MLBr_00556|M.leprae_Br4923 PLYGIFIVWLFS-----------DWRYVFWINIPLTAIAMLMIQVSLSAH
** : .* :.
Mflv_3055|M.gilvum_PYR-GCK PR-YLVATHKIPEARRVLSMLLG-QKNLEITITRIRETLEREDRP-----
Mvan_3472|M.vanbaalenii_PYR-1 PR-YLVASHKIPEARRVLSMLLG-KKNLEITITRIRETLEREDKP-----
TH_2640|M.thermoresistible__bu PR-YLVATHRVPEARRVLSRLLG-AKNLEITINRIERSLRAEKPP-----
Mb3364|M.bovis_AF2122/97 AR-WYLLKGRIADARSALRRIQP-EADIDAELADMAAAV-DERGG-----
Rv3331|M.tuberculosis_H37Rv AR-WYLLKGRIADARSALRRIQP-EADIDAELADMAAAV-DERGG-----
MMAR_1191|M.marinum_M PR-WYVMKGRIQEARAALLRVDP-AADVEEELAEIGTAL-SEGSG-----
MUL_1444|M.ulcerans_Agy99 PR-WYVMKGRIQEARAALLRVDP-AADVEEELAEIGTAL-SEGSG-----
MAV_4306|M.avium_104 AR-WYLLKGRVDDARRALLRVEP-AARVDDELAEIGRAV-SEEAASLPA-
MAB_0365c|M.abscessus_ATCC_199 AR-WYMMRGDRARAREVLSMVDR-DVDIDHELDEIAEALRAEGGGSVRA-
MSMEG_5559|M.smegmatis_MC2_155 PR-WLIKDGDPDKAREVLERVRPDGYDIDGELDEMTTLVRKEQTAKTR--
MLBr_00556|M.leprae_Br4923 DRGDELEKVDVVGGVLLAIALGLVVIGLYNPQPDSKQVLPSYGVPVLVGG
* : . : : :
Mflv_3055|M.gilvum_PYR-GCK -------------SWRDLKKPTGGIYGIVWVGLGLSIFQQFVGINVIFYY
Mvan_3472|M.vanbaalenii_PYR-1 -------------SWRDMRKPTGGLYGIVWVGLGLSIFQQFVGINVIFYY
TH_2640|M.thermoresistible__bu -------------SWSDLRKPTGGMYGIVWVGLGLSIFQQFVGINVIFYY
Mb3364|M.bovis_AF2122/97 -------------GIGEMVRRP--YLRATLFVIALGFLVQITGINAIIYY
Rv3331|M.tuberculosis_H37Rv -------------GIGEMVRRP--YLRATLFVIALGFLVQITGINAIIYY
MMAR_1191|M.marinum_M -------------GVSEMLRPP--FLRATIFVITLGFLIQITGINAIIYY
MUL_1444|M.ulcerans_Agy99 -------------GVSEMLRPP--FLRATIFVITLGFLIQITGINAIIYY
MAV_4306|M.avium_104 -------------MLAEMVRSP--YRRATVFVVVLGFLIQITGINAIIYY
MAB_0365c|M.abscessus_ATCC_199 -------------RLREMVTAP--YRRATFFVVGLGFFIQITGINAVVYY
MSMEG_5559|M.smegmatis_MC2_155 -------------GWPGLRAAW--VRPALILGCGIAIFTQLSGIEMIIYY
MLBr_00556|M.leprae_Br4923 IVATVAFAVWERCARTRLIDPAGVHIRPFLSALGASVAAGAALMVTLVNV
: .. : :.
Mflv_3055|M.gilvum_PYR-GCK SNVLWQAVGFSADESAVYT-VITSVVNVLTTLIAIALIDKIGRKPLLLIG
Mvan_3472|M.vanbaalenii_PYR-1 SNVLWQAVGFSADESAVYT-VITSVINVLTTLIAIALIDKIGRKPLLLIG
TH_2640|M.thermoresistible__bu SNVLWEAVGFDESQSFLIT-VITSVTNIVTTLIAIALIDKIGRKPLLLIG
Mb3364|M.bovis_AF2122/97 SPRLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSG
Rv3331|M.tuberculosis_H37Rv SPRLFAAMGFAGYFAMLALPAMVQVAGLAAVCASLFLVDRLGRRPILLSG
MMAR_1191|M.marinum_M SPRIFEAMGFTGDFALLGLPALVQIAGVAAVITSLLLVDRVGRRPILLSG
MUL_1444|M.ulcerans_Agy99 SPRIFEAMGFTGDFALLGLPALVQIAGVAAVITSLLLVDRVGRRPILLSG
MAV_4306|M.avium_104 SPRIFEAMGFTGNFALLALPALVQVAGLVAVGTALLLVDRVGRRPILLCG
MAB_0365c|M.abscessus_ATCC_199 GPRIFEAMGMSGYFAKLGLPALVQVAALLAVFISMSSIDRMGRRPILMIG
MSMEG_5559|M.smegmatis_MC2_155 SPTILTDNGFS-ESVALQVSVALGVSYLVAQLVGLSIIDKVGRRRLTLIM
MLBr_00556|M.leprae_Br4923 ELFGQGVLGMDQTQAAGLLVWFLIALPIGAVLGGWG-ATKAGDRTMTFVG
*: : : . : * : : :
Mflv_3055|M.gilvum_PYR-GCK SVGMAVTLSTMAFIFANAELIENEAGEMVPSLPGASGVIALIAANLFVVA
Mvan_3472|M.vanbaalenii_PYR-1 SSGMAVTLITMAVIFANATVGADGN----PSLPGASGVIALIAANLFVVA
TH_2640|M.thermoresistible__bu STGMAGTLGVMAVIFGTAPVIDGQP-----QLGDVAGPVALVAANLFVVS
Mb3364|M.bovis_AF2122/97 IATMITADAVLITVFANDSD------------GGTGLVLGFAGVLLFIIG
Rv3331|M.tuberculosis_H37Rv IATMITADAVLITVFANDSD------------GGTGLVLGFAGVLLFIIG
MMAR_1191|M.marinum_M IAIMIVADVALMAVFAR---------------GQGAAILGFAGILLFIIG
MUL_1444|M.ulcerans_Agy99 IAIMIVADVALMAVFAR---------------GQGAAILGFAGILLFIIG
MAV_4306|M.avium_104 TAMMIVADVVLVAVFGR---------------GPGGVIAGFAGVLLFIFG
MAB_0365c|M.abscessus_ATCC_199 IGIMIVADALLVGVFAVGGSS----------FGGLLTFLGFLGIVLIAVG
MSMEG_5559|M.smegmatis_MC2_155 IPGAAVSLFVLGTLFATGHS------------GRDSVPFIVACLVVFMLF
MLBr_00556|M.leprae_Br4923 LLITAGGYWLISHWPVDLLNYR----------RSIFGLFSVPTMYADLLV
: . .
Mflv_3055|M.gilvum_PYR-GCK FGMSWGPVVWVLLGEMFPNRIRAAA--LGLAAAGQWTANWVITVSFPELR
Mvan_3472|M.vanbaalenii_PYR-1 FGMSWGPVVWVLLGEMFPNRIRAAA--LGLAAAGQWAANWLITVTFPGLR
TH_2640|M.thermoresistible__bu FGMSWGPVVWVLLGEMFPNRIRAAA--LGLAAAGQWTANWVITVTFPGLR
Mb3364|M.bovis_AF2122/97 FNFGFGSLVWVYAAESFPSRLRSMG--SSLMLTSTLTANAIVAAFSLTML
Rv3331|M.tuberculosis_H37Rv FNFGFGSLVWVYAAESFPSRLRSMG--SSPMLTSTLTANAIVAAFSLTML
MMAR_1191|M.marinum_M YTMGFGSLGWVYASESFPTRLRSIG--SSTMLTANLIANAIVAGVFLTML
MUL_1444|M.ulcerans_Agy99 YTMGFGSLGWVYASESFPTRLRSIG--SSTMLTANLIANAIVAAVFLTML
MAV_4306|M.avium_104 YTMGFGSLGWVYASESFPSRLRSIG--SSTMLTSNLVANAIVAAVFLTLL
MAB_0365c|M.abscessus_ATCC_199 FTFGFGSLVWVYAGESFPARLRSYG--ASAMLTSDLVANAVVSMYFLTLL
MSMEG_5559|M.smegmatis_MC2_155 NAGGLQLMGWLTGSETYPLAVRPAG--TAAQSAALWGTNLLITLTLLTLI
MLBr_00556|M.leprae_Br4923 AGLGLGLVIGPLSSATLRVVPTAQHGIASAAVVVARMTGMLIGVAALTAW
. : . . . . :. ::
Mflv_3055|M.gilvum_PYR-GCK NFLG--AAYGFYALCAVLSGLFVWKWVRETKGVS----------------
Mvan_3472|M.vanbaalenii_PYR-1 EHLG--LAYGFYGLCAVLSGLFVWRWVMETKGVS----------------
TH_2640|M.thermoresistible__bu EHLG--PAYGFYALCAVLSLLFVWRWVAETKGRT----------------
Mb3364|M.bovis_AF2122/97 RVLGGAGVFAVFGTFAVVAFVVVYRFAPETKGRK----------------
Rv3331|M.tuberculosis_H37Rv RVLGGAGVFAVFGTFAVVAFVVVYRFAPETKGRK----------------
MMAR_1191|M.marinum_M HSLGGSGAFAVFGVLALVAFGVVYRYAPETKGRQ----------------
MUL_1444|M.ulcerans_Agy99 HSLGGSGAFAVFGVLALVAFGVVYRYAPETKGRQ----------------
MAV_4306|M.avium_104 HSLGGAGTFAVFAVLAVVAFAFVHRYAPETKGRQ----------------
MAB_0365c|M.abscessus_ATCC_199 TALGGVVAFGVFGVLATAALVFVHVLAPETKGRN----------------
MSMEG_5559|M.smegmatis_MC2_155 SGIGVGPAMWLYGLFNVAAWLFVYFRMPDLTGRS----------------
MLBr_00556|M.leprae_Br4923 GLYRFNQILAGLSTAVPPDATLIERAAAVADQAKRAYTMMYSDIFMITAI
. .:
Mflv_3055|M.gilvum_PYR-GCK ---LEDMHGEILHGDKS-ATG-------
Mvan_3472|M.vanbaalenii_PYR-1 ---LEDMHGEILHADKT-ATG-------
TH_2640|M.thermoresistible__bu ---LEDMQPDVPGHDRASAPG-------
Mb3364|M.bovis_AF2122/97 ---LEEIRHFWENGGRWPAERSPAADEP
Rv3331|M.tuberculosis_H37Rv ---LEEIRHFWENGGRWPAERSPAADEP
MMAR_1191|M.marinum_M ---LEEIRHFWENGGRWPEKLTEAP---
MUL_1444|M.ulcerans_Agy99 ---LEEIRHFWENGGRWPEKLTEAP---
MAV_4306|M.avium_104 ---LEDIRHFWENGGRWD----------
MAB_0365c|M.abscessus_ATCC_199 ---LEEIRHFWESGGTWPET--------
MSMEG_5559|M.smegmatis_MC2_155 ---LEEIEGKLRDGKFRPADFAR-----
MLBr_00556|M.leprae_Br4923 VCVIGALLGLLISSRKEHASEPKVPE--
: :