For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VRAAAVQMSPVLYSRDETVAKVVGIIDELGRAGVQFATFPETVVPYYPYFSFVQRPFEMSVEHLKLYDQA VSIPSSAVDDLAGAAKAAGMVVSVGVTERDGGSLYNTQLLFDADGSLVQRRRKTIPTYHERMIWGRGDGS GLFAVDSAVGRIGQLACWEHYNPLARYALIADGEQIHSAMFPGSFGGPLFAEQTELSVRNHALESGAFVV TATGWLDSDQQAQIMADTGCPIEPISGGNFTAIVSPSGELLGGRACSGEGSVIADLDLSLIERRKSKMDA AGHYSRPELMSLLVDRTPAAHVHDLGPSAPPAPRHHGHDAPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4138 | - | - | 100% (322) | aliphatic nitrilase |
| M. smegmatis MC2 155 | MSMEG_1120 | - | 9e-36 | 32.15% (311) | nitrilase/cyanide hydratase and apolipoprotein |
| M. smegmatis MC2 155 | MSMEG_5373 | - | 2e-32 | 30.19% (308) | nitrilase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2818c | - | 1e-09 | 26.88% (279) | putative hydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2485 | - | 2e-05 | 28.75% (160) | PUTATIVE - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1219 | - | 1e-10 | 33.33% (171) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_2818c|M.abscessus_ATCC_199 MTVIRAALTQATWTGDKESMLAKHERFVAQAAARGAQVICFQELFYGPYF
Mvan_1219|M.vanbaalenii_PYR-1 ---MKVGAVAAHFGRDVDRGVAKVVGIVEAAARDGVQLLVFPDACLGGYI
TH_2485|M.thermoresistible__bu -MVLAAAIQLEAVLGDVAANLATCERLADEAGRAGAKIIALPEFFT---T
MSMEG_4138|M.smegmatis_MC2_155 --MRAAAVQMSPVLYSRDETVAKVVGIIDELGRAGVQFATFPETVVPYYP
.. . :*. : . *.:. : :
MAB_2818c|M.abscessus_ATCC_199 GIVQDK----------KYYGYAEPVPGPVTERFAKLAREHRMVLVLPVYE
Mvan_1219|M.vanbaalenii_PYR-1 GDLRRP----------DPSDPPPALDPDGPEIAAVIAAAGPMTVCVGYAE
TH_2485|M.thermoresistible__bu GIGFDE----------SLGHAVLPPDGKATALLTSLAKRYGALVGGSFLC
MSMEG_4138|M.smegmatis_MC2_155 YFSFVQRPFEMSVEHLKLYDQAVSIPSSAVDDLAGAAKAAGMVVSVGVTE
. . : * :
MAB_2818c|M.abscessus_ATCC_199 QEQPGVLYNTAAVVDSDGRYLGKYRKHHIPHLDRFWEKFYFRPGNLGYPV
Mvan_1219|M.vanbaalenii_PYR-1 AAPGGSRYNSAICVSGDG-VLGTHRKVHQPAG----ESLAYLAGDT-FAA
TH_2485|M.thermoresistible__bu RDADGEVRNAYLAADPGG-VIGRHDKDRPTMWEN-----AFYIGGADDGV
MSMEG_4138|M.smegmatis_MC2_155 RD-GGSLYNTQLLFDADGSLVQRRRKTIPTYHER---MIWGRGDGSGLFA
* *: . .* : * . .. .
MAB_2818c|M.abscessus_ATCC_199 FDTAVGKIGVYICYDRHFPEGWRNYGLAGAELVFNPSATKPGLSN-----
Mvan_1219|M.vanbaalenii_PYR-1 FDTPVGRLGMLIDYDKTFPESARALALDGAHIIAALSAWPASVTDRASRL
TH_2485|M.thermoresistible__bu FRYGDHHVGAAVCWELMRTPTVHRLRSR-VDLVLTGSGWWSIPPWPPRAL
MSMEG_4138|M.smegmatis_MC2_155 VDSAVGRIGQLACWEHYNPLARYALIADGEQIHS--AMFPGSFGGPLFAE
. ::* :: . .: :
MAB_2818c|M.abscessus_ATCC_199 ------RLWELEQPAAAAANQYF---VGANNRIGAESGEFGDQAVSFYG-
Mvan_1219|M.vanbaalenii_PYR-1 PADRQSRLFDLYDCARAAENQVV---VVSANQTGIMG------SLRFLG-
TH_2485|M.thermoresistible__bu FERWEERNRATARAAAATFAKYVGAPVVHAAHAGELTCRMPWAPITYRGR
MSMEG_4138|M.smegmatis_MC2_155 QTELSVRNHALESGAFVVTATGW----LDSDQQAQIMADTGCPIEPISGG
* * .. : . *
MAB_2818c|M.abscessus_ATCC_199 ---SSYFVDPRGNYVGEIGSATDEEIVIRDLDLS----LVRQVRDDWQFY
Mvan_1219|M.vanbaalenii_PYR-1 ---QAKVVGPGGDVLATTRSKGGLARVDIDVEAE----IAR-ARRVLDHL
TH_2485|M.thermoresistible__bu FEGSTLITDADGTVIAERRPEEGQGVVLGEIDLGRRPPLLDPPRRYWLHP
MSMEG_4138|M.smegmatis_MC2_155 --NFTAIVSPSGELLGG-RACSGEGSVIADLDLS----LIERRKSKMDAA
: .... * :. . . * ::: : :
MAB_2818c|M.abscessus_ATCC_199 R-------------------DRRPDTYGPIIAP-----------
Mvan_1219|M.vanbaalenii_PYR-1 A-------------------ERRVDTYSTTARS-----------
TH_2485|M.thermoresistible__bu RGPLPAAVWHYQRWHGRRWYRRHMRSARGASGPS----------
MSMEG_4138|M.smegmatis_MC2_155 G---HYSRPELMSLLVDRTPAAHVHDLGPSAPPAPRHHGHDAPA
: .