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MAMMNGELRIAIAQKAPVFLNRAATTELVLSTIAEAAAAGARLVVFPETFLPGYPMWVCRTDGAVFDDAD QKAAHAYYLDQAVEADGPELRSIAQCARDHGVLVYLGIAERGHAAARGTVFCSLATIEPERGHVTIHRKL LATYDERLVWGHGDGYGLRCHNLDGVNLGGLICWENWMPQARHALYADGEDVHISVWPGNKSLTKDISRF IALEGRVWSVAAAAVLTSEHIPADFPLAEQLAARGPETYFDGGSAVVSPTGEFVVEPVVGEERLIIADLS SAAVREERLLFDATGHYARPDVFTCTVDRRRRDPVQFVDGQGVSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1120 | - | - | 100% (325) | nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase |
| M. smegmatis MC2 155 | MSMEG_5373 | - | 5e-90 | 50.64% (312) | nitrilase 2 |
| M. smegmatis MC2 155 | MSMEG_4138 | - | 9e-36 | 32.15% (311) | aliphatic nitrilase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0819 | - | 2e-09 | 30.57% (193) | carbon-nitrogen hydrolase family protein |
| M. marinum M | MMAR_0805 | - | 6e-06 | 27.74% (292) | amidohydrolase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_0873 | - | 3e-05 | 25.86% (290) | POSSIBLE AMIDOHYDROLASE |
| M. ulcerans Agy99 | MUL_4548 | - | 1e-05 | 27.40% (292) | amidohydrolase |
| M. vanbaalenii PYR-1 | Mvan_1224 | - | 1e-06 | 21.86% (247) | Nitrilase/cyanide hydratase and apolipoprotein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0805|M.marinum_M -------MRIALAQILS-GTDPTANLELVRDYAERAADAGARLVVFPEAT
MUL_4548|M.ulcerans_Agy99 -------MRIALAQILS-GTDPTANLELVRDYAERAADAGARLVVFPEAT
TH_0873|M.thermoresistible__bu -------MRIALAQIRS-GTDPSANLNLVEEYTRRAAATGAGLVLFPEAT
MAB_0819|M.abscessus_ATCC_1997 ---MTGRLRLAVVQCSSQAADVQANLARLAETAHAAAAGDAQLVVFPEMY
MSMEG_1120|M.smegmatis_MC2_155 MAMMNGELRIAIAQKAPVFLNRAATTELVLSTIAEAAAAGARLVVFPETF
Mvan_1224|M.vanbaalenii_PYR-1 -------MTTLAAVSANFTRDLEQNYALIASLADEARHRGVDFLTLPEAA
: . : . : . * .. :: :**
MMAR_0805|M.marinum_M MCRFGV--------------------PLGPVAQPLDGPWANGVRRIAAQT
MUL_4548|M.ulcerans_Agy99 MCRFGV--------------------PLGPVAQPLDGPWANGVRRIAAQT
TH_0873|M.thermoresistible__bu MCRFGV--------------------SLKPVAEPLDGPWATAVREIAAGA
MAB_0819|M.abscessus_ATCC_1997 LTGYNIGEW-----------------DIRDLAQSPDGPAMQFIRQTACDA
MSMEG_1120|M.smegmatis_MC2_155 LPGYPMWVCRTDGAVFDDADQKAAHAYYLDQAVEADGPELRSIAQCARDH
Mvan_1224|M.vanbaalenii_PYR-1 IGGYLSSLG-------NHGDTVRTTARSLPPAIRLDGPEIARVQQIVG--
: : * *** : . .
MMAR_0805|M.marinum_M GITVVAGMFTP---ADAGRVSNTLFAAGPGAPNQPDDHYHKIHLYDAFGF
MUL_4548|M.ulcerans_Agy99 GITVVAGMFTP---ADAGRVSNTLFAAGPGAPNQPDDHYHKIHLYDAFGF
TH_0873|M.thermoresistible__bu GVVVVAGMFTP---SGDGRVTNTLLATGPGVA----AHYHKIHLYDAYGF
MAB_0819|M.abscessus_ATCC_1997 DMHICVGYPER---ASDGQIYNSALICDPRGR--VVLNYRKSHLFGDT--
MSMEG_1120|M.smegmatis_MC2_155 GVLVYLGIAERGHAAARGTVFCSLATIEPERG----HVTIHRKLLATYDE
Mvan_1224|M.vanbaalenii_PYR-1 DLVVAIGFCEL---ADDGHTRYNAAAVLDGST----VYGSYRKVHQPLGE
.: : * : * . ::
MMAR_0805|M.marinum_M AESRTVAPGHEPVVITVDDVQVGLTVCYDIRFPALYTELARRGAELIVVS
MUL_4548|M.ulcerans_Agy99 AESRTVAPGHEPVVITVDDFQVGLTVCYDIRFPALYTELARRGAELIVVS
TH_0873|M.thermoresistible__bu TESRTVAPGSEPVTIDVGGVRVGLTTCYDIRFPELYVELARRGAELLTVH
MAB_0819|M.abscessus_ATCC_1997 ERNVFTRPGPQLPLAVVHGVSVGLLICYDVEFPENVRALAMARADVVVVP
MSMEG_1120|M.smegmatis_MC2_155 RLVWGHGDGYGLRCHNLDGVNLGGLICWENWMPQARHALYADGEDVHISV
Mvan_1224|M.vanbaalenii_PYR-1 GMSYSAGSGYGVFDTPIG--RVGLQICYDKAFPEAARIMALRGAQVIASL
* : :* *:: :* : ::
MMAR_0805|M.marinum_M ASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDT--ASDPGGGSG
MUL_4548|M.ulcerans_Agy99 ASWGSGPGKLDQWTLLARARALDSASYVAAAGQADPGDT--ASDPGGGSG
TH_0873|M.thermoresistible__bu ASWGSGPGKLEQWTLLARARALDTTCVVAAVGQAYPGDE--IAAQG----
MAB_0819|M.abscessus_ATCC_1997 TAN--MEPFHAVCETVVPARAYENQLYVAYANYCGNHDG--LAYCG----
MSMEG_1120|M.smegmatis_MC2_155 WPGNKSLTKDISRFIALEGRVWSVAAAAVLTSEHIPADFPLAEQLAARGP
Mvan_1224|M.vanbaalenii_PYR-1 SAWP--AARTATAENLQDDRWTYRFNLFDTARALDNQVFWVASNQSGTFG
. * . .
MMAR_0805|M.marinum_M APRGVGGSLVASPLGEVVASAGSDPQ-LVVADIDLAKVGAARDNIGVLRN
MUL_4548|M.ulcerans_Agy99 APRGVGGSLVTSPLGEVVASAGSDPQ-LVVADIDLAKVGAARDNIGMLRN
TH_0873|M.thermoresistible__bu -PTGVGGSLVASATGEVLAAAGPEPE-LLVADLDLDAARRARDTIAVLRN
MAB_0819|M.abscessus_ATCC_1997 ------GSSIVGPDGTALARAGEGVG-LLVADVDRAVIDRTRSRHCFLED
MSMEG_1120|M.smegmatis_MC2_155 ETYFDGGSAVVSPTGEFVVEPVVGEERLIIADLSSAAVREERLLFDATGH
Mvan_1224|M.vanbaalenii_PYR-1 SLRYVGNAKVVDPGGNILATTLLGSG-MAVAEVDIDETFRTMRAGMFHLR
.: :... * :. . : :*::.
MMAR_0805|M.marinum_M QSRFTQTDKAQSRR---------------
MUL_4548|M.ulcerans_Agy99 QSRFTQTDKAQSRR---------------
TH_0873|M.thermoresistible__bu RSDVAQWGKAESVG---------------
MAB_0819|M.abscessus_ATCC_1997 RVARAISP---------------------
MSMEG_1120|M.smegmatis_MC2_155 YARPDVFTCTVDRRRRDPVQFVDGQGVSR
Mvan_1224|M.vanbaalenii_PYR-1 DRRPDVYGPITEVGAGSDLAHA-------