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MPARIDPVERRSHIVEAALRLVLKEGLSAATFRRVAAESQLNIGSVRHYFADHESLVVAVVTEAGNRMGQ RLMKHTPPQSRDLSRQRQHLIALLEELVPLDAERHSEAVILMEVIAASRTTEAFRAATAQMATDLDDVLV TALKGMSVPQPSLEAQRLASLLSGLALDAVTAHGPRKPTTIAKILRLHVDSLPTSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4129 | - | - | 100% (196) | hypothetical protein MSMEG_4129 |
| M. smegmatis MC2 155 | MSMEG_3177 | - | 6e-07 | 26.60% (188) | transcriptional regulatory protein, putative |
| M. smegmatis MC2 155 | MSMEG_2049 | - | 6e-07 | 24.85% (165) | putative transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 2e-09 | 34.00% (100) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1588 | - | 5e-06 | 27.54% (138) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 2e-09 | 34.00% (100) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0341 | - | 2e-05 | 25.50% (200) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1611 | - | 5e-08 | 44.44% (63) | transcriptional regulatory protein |
| M. avium 104 | MAV_0847 | - | 2e-06 | 31.50% (127) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4317 | - | 2e-06 | 27.14% (70) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3426 | - | 4e-08 | 44.44% (63) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5312 | - | 2e-05 | 22.04% (186) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3093|M.bovis_AF2122/97 -----------------------------------MTAGSDRRPRDPAGR
Rv3066|M.tuberculosis_H37Rv -----------------------------------MTAGSDRRPRDPAGR
MMAR_1611|M.marinum_M -----------------------------------MTREVERRPRDPAGR
MUL_3426|M.ulcerans_Agy99 -----------------------------------MTREVERRPRDPAGR
Mflv_1588|M.gilvum_PYR-GCK -----------------------------------MPAAAKSRPADARGR
MAV_0847|M.avium_104 --------------------------------------------------
MSMEG_4129|M.smegmatis_MC2_155 -----------------------------------MPAR-----IDPVER
MAB_0341|M.abscessus_ATCC_1997 -----------------------------------------MPYVESAQR
Mvan_5312|M.vanbaalenii_PYR-1 MSGTSEFAADKSQTSARATSGAGSESRPRQVMNVAVLAESELGSEAQRER
TH_4317|M.thermoresistible__bu ----------------------------------------------MSQQ
Mb3093|M.bovis_AF2122/97 RQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAA
Rv3066|M.tuberculosis_H37Rv RQAIVEAAERVIARQGLGGLSHRRVAAEANVPVGSTTYYFNDLDALREAA
MMAR_1611|M.marinum_M RQTIIEAAGRLIARHGLGDLTHRRVAAEADVPVGSTTYYFSDLGELREAA
MUL_3426|M.ulcerans_Agy99 RQTIIEAAGRLIARHGLGDLTHRRVAAEADVPVGSTTYYFSDLGELREAA
Mflv_1588|M.gilvum_PYR-GCK ---LIEATAKVMRDEGYAAATSRRVAAEAGVKQALVYYYFPTMDDLFVEV
MAV_0847|M.avium_104 ---MIEATARLMREEGYAAATSRRVAAEAGVKQALVYYYFPTMDDLFVEV
MSMEG_4129|M.smegmatis_MC2_155 RSHIVEAALRLVLKEGLSAATFRRVAAESQLNIGSVRHYFADHESLVVAV
MAB_0341|M.abscessus_ATCC_1997 TKEAVAAARIVLMREGVGRTTMRAVAAEAGIPLGTLQYVFPSKQGLLKAV
Mvan_5312|M.vanbaalenii_PYR-1 RKRILDATLAIASKGGYEAVQMRAVAERADVAVGTLYRYFPSKVHLLVSA
TH_4317|M.thermoresistible__bu YDRMVDVVLSVLVSDGFEGVSVRKVAARANVSIGAVQHHFPTKDAMLQAA
: .. : * * ** .: : . * : .
Mb3093|M.bovis_AF2122/97 LAHAANASADLLAQWRSDLDKDR-----DLAATLARLTTVYLADQDRYR-
Rv3066|M.tuberculosis_H37Rv LAHAANASADLLAQWRSDLDKDR-----DLAATLARLTTVYLADQDRYR-
MMAR_1611|M.marinum_M LAHVATSATDWLEHWERDLDEST-----DIPATLARLTADYLTDPDRHR-
MUL_3426|M.ulcerans_Agy99 LAHVATSATDWLEHWERDLDEST-----DIPATLARLTADYLTDPDRHR-
Mflv_1588|M.gilvum_PYR-GCK LRVGGESSLEHMRAALTNDDPLRALWLINSEAGRTGLNAEFMALANHRK-
MAV_0847|M.avium_104 LRAGAESALTRMRALLTEDDPLQALWLMNSDTALTALNAEFMALANHRK-
MSMEG_4129|M.smegmatis_MC2_155 VTEAGNRMGQRLMKHTPPQSRDLS----RQRQHLIALLEELVPLDAERHS
MAB_0341|M.abscessus_ATCC_1997 IEDVVDEIAGVLRGAADTKAGLN-------DAVRRGTRNFWSQLVDEHRN
Mvan_5312|M.vanbaalenii_PYR-1 LGREFERIDAKTDRSAFPAGATAY-----QRLNIMVGKLNRAMQRNPLLT
TH_4317|M.thermoresistible__bu MDTAARRFRQRLAERMDPTMPAA-----EQLETVAVALACADPAERETAV
:
Mb3093|M.bovis_AF2122/97 --TLN-ELYMAAAHRPELQRLARLWPDGLLALLEPRIG--RRAANAVTVF
Rv3066|M.tuberculosis_H37Rv --TLN-ELYMAAAHRPELQRLARLWPDGLLALLEPRIG--RRAANAVTVF
MMAR_1611|M.marinum_M --TLN-ELYVAASHQPELQSLAQLWSDGLVALLEPRIG--PRAARVVSIF
MUL_3426|M.ulcerans_Agy99 --TLN-ELYVAASHQPELQSLAQLWSDGLVALLEPRIG--PRAARVVSIF
Mflv_1588|M.gilvum_PYR-GCK --AIRVELKAYAERVRDIETAAVTVALRANGVDLQEHP--PVVVSMLIAQ
MAV_0847|M.avium_104 --AIGAELKAYAERVRDIETAAATMVLRANGIDLEEYP--PVAISMLIAQ
MSMEG_4129|M.smegmatis_MC2_155 EAVILMEVIAASRTTEAFRAATAQMATDLDDVLVTALKGMSVPQPSLEAQ
MAB_0341|M.abscessus_ATCC_1997 LQLVQYELVTHALRTSGLEDLPAWQYERYTGVVADWCREAASRAGERCAV
Mvan_5312|M.vanbaalenii_PYR-1 EAMTRAFVFADASAAGEVDHVGKLMDSMFARAMSDGEP--TEDQYHIARV
TH_4317|M.thermoresistible__bu TWLLRLARAAVNEQVAERHRSEWRALEALLRDLIXXXHHARRACADRGQL
Mb3093|M.bovis_AF2122/97 FDGATLHALITGTP--LSTDELTDAIARLVADGPEQREVGQSAHAGRTPD
Rv3066|M.tuberculosis_H37Rv FDGATLHALITGTP--LSTDELTDAIARLVADGPEQREVGQSAHAGRTPD
MMAR_1611|M.marinum_M LDGATLHAMISDTP--LDAPALTDAIARLVGN-----DTGTPGSR-----
MUL_3426|M.ulcerans_Agy99 LDGATLHAMISDTP--LDAPALTDAIARLVGN-----DTGTPGSR-----
Mflv_1588|M.gilvum_PYR-GCK IARSLCNEDAVGVT--LGHEEMRAWVDRQLAL-----LAAEPGG------
MAV_0847|M.avium_104 AARSLCNEKAVGVT--QGHDELRAFVQRQLSR-----LTAPAVASTTSA-
MSMEG_4129|M.smegmatis_MC2_155 RLASLLSGLALDAV--TAHGPRKPTTIAKILR---LHVDSLPTSR-----
MAB_0341|M.abscessus_ATCC_1997 SFERLARVLVAGIDGLILQHVVNPDPARSEEDLESLTAMLIALAAVTPA-
Mvan_5312|M.vanbaalenii_PYR-1 ISDVWLSNLLAWLT---RRASATDVAKRLDLAVRLLIGDGDQPKI-----
TH_4317|M.thermoresistible__bu PHRAVLAGGQGTTAGGAAVRRVRHLSAAADAVLPEVPVQGRQLGPAQR--