For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VARSAKGNVAHGDGRQALIVATVSLVAREGLSKLTYRSLAAEANVTHGTIQHHFSSLDEVLEEALNYALD VTLPAITEARDAGDFYTHLVDVIAEHRDVQAFQMEMILESRRKPRMAAYVKQLYGIYDRYIAESLAQIGL PDDDELAQLVSGVGDGIVYQLIALGPDHAEKARAQVRGLSKLIAAYRKSTGGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2049 | - | - | 100% (193) | putative transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_4129 | - | 6e-07 | 24.40% (168) | hypothetical protein MSMEG_4129 |
| M. smegmatis MC2 155 | MSMEG_6503 | - | 6e-06 | 25.16% (159) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 6e-08 | 37.88% (66) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1270 | - | 3e-05 | 37.25% (51) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 6e-08 | 37.88% (66) | DeoR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0341 | - | 7e-08 | 26.70% (191) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1611 | - | 5e-08 | 31.25% (144) | transcriptional regulatory protein |
| M. avium 104 | MAV_0603 | - | 1e-05 | 35.71% (56) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4019 | - | 1e-07 | 28.39% (155) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3426 | - | 3e-08 | 31.25% (144) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_5169 | - | 9e-07 | 26.11% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3093|M.bovis_AF2122/97 ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
Rv3066|M.tuberculosis_H37Rv ---MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHRRVAAEANVP
MMAR_1611|M.marinum_M ---MTREVERRPRDPAGRRQTIIEAAGRLIARHGLGDLTHRRVAAEADVP
MUL_3426|M.ulcerans_Agy99 ---MTREVERRPRDPAGRRQTIIEAAGRLIARHGLGDLTHRRVAAEADVP
Mflv_1270|M.gilvum_PYR-GCK ---MATSSRRVGAETSKTRDTLLDCVETMMLEEGYASVTYRALAAKAGVT
Mvan_5169|M.vanbaalenii_PYR-1 ---MAASPKGRGSDP-NARQRLIEATARVMRDEGYAAATSRRVAAEAGVK
TH_4019|M.thermoresistible__bu MVDAGETTDGRRARGQRRRAEIIDATLAVVERDGAAGVTHRAVAAEAGIP
MSMEG_2049|M.smegmatis_MC2_155 ---MARSAKG-NVAHGDGRQALIVATVSLVAREGLSKLTYRSLAAEANVT
MAB_0341|M.abscessus_ATCC_1997 ---------MPYVESAQRTKEAVAAARIVLMREGVGRTTMRAVAAEAGIP
MAV_0603|M.avium_104 ----------MTGPANSRRDELLELAAAMFAERGLRATTVRDIADSAGIL
: . :. * : * :* .*.:
Mb3093|M.bovis_AF2122/97 VGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLDKDRDLAATLARL
Rv3066|M.tuberculosis_H37Rv VGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLDKDRDLAATLARL
MMAR_1611|M.marinum_M VGSTTYYFSDLGELREAALAHVATSATDWLEHWERDLDESTDIPATLARL
MUL_3426|M.ulcerans_Agy99 VGSTTYYFSDLGELREAALAHVATSATDWLEHWERDLDESTDIPATLARL
Mflv_1270|M.gilvum_PYR-GCK PSLVQYYFPTLDDVFIAAIRRYSERN---LAHLNKVMEKR---AEDPLRA
Mvan_5169|M.vanbaalenii_PYR-1 QALVYYYFPTMDDLFVEVLRAGGESA---LEHMRAALTN-----DDPLHA
TH_4019|M.thermoresistible__bu ASLTAYYFATLDDLLVAALSSVADGY---TERIREIIERPGDRLRGLAEL
MSMEG_2049|M.smegmatis_MC2_155 HGTIQHHFSSLDEVLEEALNYALDVTLPAITEARDAGDFYTHLVDVIAEH
MAB_0341|M.abscessus_ATCC_1997 LGTLQYVFPSKQGLLKAVIEDVVDEIAGVLRGAADTKAGLNDAVRRGTRN
MAV_0603|M.avium_104 SGSLYHHFSSKEEMVDEVLRSFLDWLFARYREIIDSESNPLERLKGLFMA
. : * : .:
Mb3093|M.bovis_AF2122/97 TTVYLAD--QDRYRTLNELYMAAAHRPELQRLARLWPDGLLALLEPRIG-
Rv3066|M.tuberculosis_H37Rv TTVYLAD--QDRYRTLNELYMAAAHRPELQRLARLWPDGLLALLEPRIG-
MMAR_1611|M.marinum_M TADYLTD--PDRHRTLNELYVAASHQPELQSLAQLWSDGLVALLEPRIG-
MUL_3426|M.ulcerans_Agy99 TADYLTD--PDRHRTLNELYVAASHQPELQSLAQLWSDGLVALLEPRIG-
Mflv_1270|M.gilvum_PYR-GCK LWEYSWD--EATGTLMTEFMALGNHRKSIRTEIAAVTESVRTLQLDALT-
Mvan_5169|M.vanbaalenii_PYR-1 LWLINND--ASRTGLNTEFMALANHRKAIRVELRAYAERVRDIETAAVT-
TH_4019|M.thermoresistible__bu IVESAGPG-RERALAERELSTLAARRPALQPVARRWRDNVAELASTLTDD
MSMEG_2049|M.smegmatis_MC2_155 RDVQAFQM-EMILESRRKPRMAAYVKQLYGIYDRYIAESLAQIGLPDDD-
MAB_0341|M.abscessus_ATCC_1997 FWSQLVDEHRNLQLVQYELVTHALRTSGLEDLPAWQYERYTGVVADWCRE
MAV_0603|M.avium_104 SFEAIEHR-HAQVVIYQDEAKRLLSQPRFSYIEDMNRQ-QRKMWLEVLN-
. : :
Mb3093|M.bovis_AF2122/97 RRAANAVTVFFDG--ATLHALITGTP-----LSTDELTDAIARLVADGPE
Rv3066|M.tuberculosis_H37Rv RRAANAVTVFFDG--ATLHALITGTP-----LSTDELTDAIARLVADGPE
MMAR_1611|M.marinum_M PRAARVVSIFLDG--ATLHAMISDTP-----LDAPALTDAIARLVGN---
MUL_3426|M.ulcerans_Agy99 PRAARVVSIFLDG--ATLHAMISDTP-----LDAPALTDAIARLVGN---
Mflv_1270|M.gilvum_PYR-GCK AKFGADARPWGDLSLPALQLLISSLPKFLNLEKGVGVETAHAELIEAFEG
Mvan_5169|M.vanbaalenii_PYR-1 VALRANGVDLDEHPPVVISMLIAQVARSLCNEVAVGVTLGHDEMRAYVER
TH_4019|M.thermoresistible__bu PQAIAALVAASDG--LCTAILIDNAP--------ADVDFAHGVLRRA---
MSMEG_2049|M.smegmatis_MC2_155 -ELAQLVSGVGDG---IVYQLIALGP--------DHAEKARAQVRGLSKL
MAB_0341|M.abscessus_ATCC_1997 AASRAGERCAVSFERLARVLVAGIDGLILQHVVNPDPARSEEDLESLTAM
MAV_0603|M.avium_104 -QGVDEGYFRPDLDVDLVYRFIRDTTWVSVRWYQPGGPLTAEQVGQQYLA
. . :
Mb3093|M.bovis_AF2122/97 QREVGQSAHAGRTPD-----
Rv3066|M.tuberculosis_H37Rv QREVGQSAHAGRTPD-----
MMAR_1611|M.marinum_M --DTGTPGSR----------
MUL_3426|M.ulcerans_Agy99 --DTGTPGSR----------
Mflv_1270|M.gilvum_PYR-GCK YLNSIEPTPKRKPVPRKRSR
Mvan_5169|M.vanbaalenii_PYR-1 QLKLLAPVTGG---------
TH_4019|M.thermoresistible__bu ---LGVPAEHQP--------
MSMEG_2049|M.smegmatis_MC2_155 IAAYRKSTGGG---------
MAB_0341|M.abscessus_ATCC_1997 LIALAAVTPA----------
MAV_0603|M.avium_104 IVLGGITVDAKKD-------