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TIPDHVGVFGGGRMGTGIAHAFLVAGASVTVIEADAGAAEAAELRIIASLEKAEQLHTLPAPMQVVKQRL TVDADPDALHGCGLIVEAVPEVTELKAAVLALIEGVAPHAVLATNTSSLSVDELATPLRQPTKFLGLHFF NPVPASQLVEIVVGTKTADDVVATAHTWIKSLDKTAITVKDAPGFASSRLGVAIALEAMRMVEDDVASVA DIDAAMTLGYKHPMGPLRTTDIVGLDVRLAIAEHLAHELGPRFEPPAILRDKVAAGELGRKAGQGFYSW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4110 | - | - | 100% (280) | 3-hydroxyacyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4115 | - | 2e-41 | 38.18% (275) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0912 | - | 5e-41 | 37.37% (281) | 3-hydroxybutyryl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0477 | fadB2 | 7e-46 | 39.79% (284) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0106 | - | 5e-51 | 41.64% (281) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. tuberculosis H37Rv | Rv0468 | fadB2 | 7e-46 | 39.79% (284) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. leprae Br4923 | MLBr_02461 | fadB2 | 2e-44 | 39.64% (280) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0904 | - | 1e-77 | 54.45% (281) | putative 3-hydroxyacyl-CoA dehydrogenase |
| M. marinum M | MMAR_0793 | fadB2 | 3e-46 | 40.14% (279) | 3-hydroxybutyryl-CoA dehydrogenase FadB2 |
| M. avium 104 | MAV_4681 | - | 2e-44 | 39.43% (279) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_3443 | - | 1e-37 | 42.50% (200) | PUTATIVE 3-hydroxybutyryl-CoA dehydrogenase FadB2 |
| M. ulcerans Agy99 | MUL_4537 | fadB2 | 7e-46 | 39.78% (279) | 3-hydroxybutyryl-CoA dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0802 | - | 4e-50 | 41.28% (281) | 3-hydroxybutyryl-CoA dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0793|M.marinum_M -----MG----SDAAIQRVGVVGAGQMGSGIAEVSVRAGVEVTVFETTEA
MUL_4537|M.ulcerans_Agy99 -----MG----SDAAIQRVGVVGAGQMGSGIAEVSVRAGVEVTAFETTEA
MAV_4681|M.avium_104 MHDKTIGGETVSDAAIQRVGVVGAGQMGSGIAEVSVRADVDVTVFETTEA
MLBr_02461|M.leprae_Br4923 ----------MSDAAIQRVGVVGAGQMGSGIAEVAVRAGVGVTVFETTDT
Mb0477|M.bovis_AF2122/97 -----------MSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEA
Rv0468|M.tuberculosis_H37Rv -----------MSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEA
TH_3443|M.thermoresistible__bu ------------------------------LRWWHARERCPX-VYDISEE
Mflv_0106|M.gilvum_PYR-GCK -------------MSIERVGVVGAGQMGSGIAEVAAKAGANVVVYEPSDA
Mvan_0802|M.vanbaalenii_PYR-1 -------------MSIERVGVVGAGQMGSGIAEVAAKAGANVVVYEPSEA
MSMEG_4110|M.smegmatis_MC2_155 ------------MTIPDHVGVFGGGRMGTGIAHAFLVAGASVTVIEADAG
MAB_0904|M.abscessus_ATCC_1997 -------MTATPHSVPTVVTVIGGGPMGAGIAQVFAAAGANVTIVETGRD
: :
MMAR_0793|M.marinum_M LITAGRNRIVKSLERGVSSGKVTERERDRALSRLTFTTDLNDLAD-RQLV
MUL_4537|M.ulcerans_Agy99 LITAGRNRIVKSLERGVSSGKVTERERDRALSRLTFTTDLNDLAD-RQLV
MAV_4681|M.avium_104 LITAGRNRIVKSLERGVSAGKVTERERDRALSKLTFTTDLKDLAD-RQLV
MLBr_02461|M.leprae_Br4923 LVTAGRNRIVKSLERGVSAGKVTERERDSALGHLVFTTDLNDLAD-RQLV
Mb0477|M.bovis_AF2122/97 LITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSD-RQLV
Rv0468|M.tuberculosis_H37Rv LITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSD-RQLV
TH_3443|M.thermoresistible__bu LTTAGRERIAKSLTRGVQAGKLSEDERSAALDRLRFTTTLADLSD-RQLV
Mflv_0106|M.gilvum_PYR-GCK LVNAGRERITASLERAKAKGKLAADDFEITLARLTFTTDLADLAD-RQLV
Mvan_0802|M.vanbaalenii_PYR-1 LVAAGRDRITASLERAKAKGKLAADDFDATVARLTFTTNLGDLAD-RQLV
MSMEG_4110|M.smegmatis_MC2_155 AAEAAELRIIASLEKAEQLHTLPAP-MQVVKQRLTVDADPDALHG-CGLI
MAB_0904|M.abscessus_ATCC_1997 RADAALQRVSAGLDRAAAKNRLAEA-PEHVLSRVDVVCSLTELPTDSELV
*. *: .* :. :. . . : . * *:
MMAR_0793|M.marinum_M IEAIIEDEAVKTKVFADLDRVVTDPDAVLASNTSSIPIMKVAAATKNPRR
MUL_4537|M.ulcerans_Agy99 IEAIIEDEAVKTKVFADLDRVVTDPDAVLASNTSSIPIMKVAAATKNPRR
MAV_4681|M.avium_104 IEAIIEDDAVKAQVFAELDRVVTDPDAVLASNTSSIPIMKLAAATKNPQR
MLBr_02461|M.leprae_Br4923 IEAIVEDEAVKTKVFAELDRVITDPDAVLASNTSSIPIMKIAAATKNPQR
Mb0477|M.bovis_AF2122/97 IEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSIPIMKVAAATKQPQR
Rv0468|M.tuberculosis_H37Rv IEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSIPIMKVAAATKQPQR
TH_3443|M.thermoresistible__bu IEAIVEDENVKATVFAELDELLTDPDAVLASNTSSIPIMKLAAATKNPGR
Mflv_0106|M.gilvum_PYR-GCK IEAIIEDEAVKAKVFAQLDEVVTDPDAVLASNTSSIPIMKIAAATKNPSR
Mvan_0802|M.vanbaalenii_PYR-1 IEAIVENEAVKAKVFAELDAVVTDPDAVLASNTSSIPIMKIAAATKNPSR
MSMEG_4110|M.smegmatis_MC2_155 VEAVPEVTELKAAVLALIEG--VAPHAVLATNTSSLSVDELATPLRQPTK
MAB_0904|M.abscessus_ATCC_1997 VEAVPENINLKIEVLGAAEKL-VEPTTVLASNTSSLSITELAAALLRPER
:**: * :* ::. : . * :***:****:.: ::*:. .* :
MMAR_0793|M.marinum_M VLGLHFFNPVPVLPLVELVSTLVTDEAAVARTEEFASAVLGKQVVRCSDR
MUL_4537|M.ulcerans_Agy99 VLGLHFFNPVPVLPLVELVNTLVTDEAAVARTEEFASAVLGKQVVRCSDR
MAV_4681|M.avium_104 VLGLHFFNPVPVLPLVELVSTLVTDEAAAARTEEFASAVLGKQVVRCSDR
MLBr_02461|M.leprae_Br4923 VLGLHFFNPVPVLPLVELVSTLVTDEAAATRAEEFASGVLGKQVVRCSDR
Mb0477|M.bovis_AF2122/97 VLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVRCSDR
Rv0468|M.tuberculosis_H37Rv VLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVRCSDR
TH_3443|M.thermoresistible__bu VLGLHFFNPVPVLPLVELINTLVTTDEAIARTEKFAAEVLGKQVVRCGDR
Mflv_0106|M.gilvum_PYR-GCK VLGLHFFNPVPVLPLVEVINTLVTSEEAVARVEQFASEVLGKKVVRCGDR
Mvan_0802|M.vanbaalenii_PYR-1 VLGLHFFNPVPVLPLVELVNTLVTSDDAIARVERFAGEVLGKKVVRCGDR
MSMEG_4110|M.smegmatis_MC2_155 FLGLHFFNPVPASQLVEIVVGTKTADDVVATAHTWIK-SLDKTAITVKDA
MAB_0904|M.abscessus_ATCC_1997 VVGMHFFNPVPTSQLVEIVRAPETSDDTVAAALAWVR-ALGKADVVARDS
.:*:*******. ***:: * : . : . : *.* : *
MMAR_0793|M.marinum_M SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MUL_4537|M.ulcerans_Agy99 SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MAV_4681|M.avium_104 SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MLBr_02461|M.leprae_Br4923 SGFVVNALLVPYLLSAIRIVEAGFATVEDVDKAVLAGLSHPMGPLRLSDL
Mb0477|M.bovis_AF2122/97 SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
Rv0468|M.tuberculosis_H37Rv SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
TH_3443|M.thermoresistible__bu SGFVVNALLVPYLLSAIRMVESGYASVEDVDKAVVAGLSHPMGPLRLSDL
Mflv_0106|M.gilvum_PYR-GCK SGFIVNALLVPYLLSAIRMAEAGVATVEDIDTAVVAGLSHPMGPLRLSDL
Mvan_0802|M.vanbaalenii_PYR-1 SGFVVNALLVPYLLSAIRMAEAGVATVEDIDTAVVAGLSHPMGPLRLSDL
MSMEG_4110|M.smegmatis_MC2_155 PGFASSRLGVAIALEAMRMVEDDVASVADIDAAMTLGYKHPMGPLRTTDI
MAB_0904|M.abscessus_ATCC_1997 PGFASSRLGVALGLEAIRMLEEGVADAESIDRAMELGYRHPMGPLRSTDL
.** . * *. *.*:*: * . * . .:* *: * ******* :*:
MMAR_0793|M.marinum_M VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGQGFYTY--
MUL_4537|M.ulcerans_Agy99 VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGQGFYTY--
MAV_4681|M.avium_104 VGLDTLKLIADKMFEEFKEPQYGAPPLLLRMVEAGRLGKKTGQGFYTY--
MLBr_02461|M.leprae_Br4923 VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGLLGKKSGQGFYTY--
Mb0477|M.bovis_AF2122/97 VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY--
Rv0468|M.tuberculosis_H37Rv VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY--
TH_3443|M.thermoresistible__bu VGLDTLKLIADKMFDEFKEPHYGPPPLLVRMVEAGHLGKKTGRGFYTY--
Mflv_0106|M.gilvum_PYR-GCK IGLDTMKLIADSMYDEYKDPNFAPPPLLQRMVEAGQLGKKSGKGFYSY--
Mvan_0802|M.vanbaalenii_PYR-1 IGLDTMKLIADSMYDEYKDPHYAPPPLLQRMVEAGQLGKKSGKGFYTY--
MSMEG_4110|M.smegmatis_MC2_155 VGLDVRLAIAEHLAHELG-PRFEPPAILRDKVAAGELGRKAGQGFYSW--
MAB_0904|M.abscessus_ATCC_1997 VGLDVRLAIAEHLCATLG-PRFTPPKLLRAKVAEGNLGRKTGQGFFRWSS
:***. **: : *.: .* :* * * **:*:*:**: :