For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. abscessus ATCC 19977 MAB_0904 (-)

annotation: putative 3-hydroxyacyl-CoA dehydrogenase
coordinates: 897240 - 898109
length: 289

MTATPHSVPTVVTVIGGGPMGAGIAQVFAAAGANVTIVETGRDRADAALQRVSAGLDRAAAKNRLAEAPE
HVLSRVDVVCSLTELPTDSELVVEAVPENINLKIEVLGAAEKLVEPTTVLASNTSSLSITELAAALLRPE
RVVGMHFFNPVPTSQLVEIVRAPETSDDTVAAALAWVRALGKADVVARDSPGFASSRLGVALGLEAIRML
EEGVADAESIDRAMELGYRHPMGPLRSTDLVGLDVRLAIAEHLCATLGPRFTPPKLLRAKVAEGNLGRKT
GQGFFRWSS

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. abscessus ATCC 19977 MAB_0904 - - 100% (289) putative 3-hydroxyacyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4094c - 2e-47 40.14% (284) 3-hydroxybutyryl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_4489c - 3e-44 40.21% (281) 3-hydroxyacyl-CoA dehydrogenase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb0477 fadB2 4e-49 41.07% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. gilvum PYR-GCK Mflv_0106 - 2e-53 43.93% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. tuberculosis H37Rv Rv0468 fadB2 4e-49 41.07% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. leprae Br4923 MLBr_02461 fadB2 4e-47 39.64% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. marinum M MMAR_0793 fadB2 2e-49 41.79% (280) 3-hydroxybutyryl-CoA dehydrogenase FadB2
M. avium 104 MAV_4681 - 2e-48 41.07% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_4110 - 2e-77 54.45% (281) 3-hydroxyacyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_3443 - 1e-42 39.61% (255) PUTATIVE 3-hydroxybutyryl-CoA dehydrogenase FadB2
M. ulcerans Agy99 MUL_4537 fadB2 2e-49 41.79% (280) 3-hydroxybutyryl-CoA dehydrogenase
M. vanbaalenii PYR-1 Mvan_0802 - 2e-53 43.93% (280) 3-hydroxybutyryl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_0793|M.marinum_M               -----MG----SDAAIQRVGVVGAGQMGSGIAEVSVRAGVEVTVFETTEA
MUL_4537|M.ulcerans_Agy99           -----MG----SDAAIQRVGVVGAGQMGSGIAEVSVRAGVEVTAFETTEA
MAV_4681|M.avium_104                MHDKTIGGETVSDAAIQRVGVVGAGQMGSGIAEVSVRADVDVTVFETTEA
MLBr_02461|M.leprae_Br4923          ----------MSDAAIQRVGVVGAGQMGSGIAEVAVRAGVGVTVFETTDT
Mb0477|M.bovis_AF2122/97            -----------MSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEA
Rv0468|M.tuberculosis_H37Rv         -----------MSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEA
TH_3443|M.thermoresistible__bu      ------------------------------LRWWHARERCPX-VYDISEE
Mflv_0106|M.gilvum_PYR-GCK          -------------MSIERVGVVGAGQMGSGIAEVAAKAGANVVVYEPSDA
Mvan_0802|M.vanbaalenii_PYR-1       -------------MSIERVGVVGAGQMGSGIAEVAAKAGANVVVYEPSEA
MAB_0904|M.abscessus_ATCC_1997      -------MTATPHSVPTVVTVIGGGPMGAGIAQVFAAAGANVTIVETGRD
MSMEG_4110|M.smegmatis_MC2_155      ------------MTIPDHVGVFGGGRMGTGIAHAFLVAGASVTVIEADAG
                                                                  :              :    

MMAR_0793|M.marinum_M               LITAGRNRIVKSLERGVSSGKVTERERDRALSRLTFTTDLNDLAD-RQLV
MUL_4537|M.ulcerans_Agy99           LITAGRNRIVKSLERGVSSGKVTERERDRALSRLTFTTDLNDLAD-RQLV
MAV_4681|M.avium_104                LITAGRNRIVKSLERGVSAGKVTERERDRALSKLTFTTDLKDLAD-RQLV
MLBr_02461|M.leprae_Br4923          LVTAGRNRIVKSLERGVSAGKVTERERDSALGHLVFTTDLNDLAD-RQLV
Mb0477|M.bovis_AF2122/97            LITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSD-RQLV
Rv0468|M.tuberculosis_H37Rv         LITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSD-RQLV
TH_3443|M.thermoresistible__bu      LTTAGRERIAKSLTRGVQAGKLSEDERSAALDRLRFTTTLADLSD-RQLV
Mflv_0106|M.gilvum_PYR-GCK          LVNAGRERITASLERAKAKGKLAADDFEITLARLTFTTDLADLAD-RQLV
Mvan_0802|M.vanbaalenii_PYR-1       LVAAGRDRITASLERAKAKGKLAADDFDATVARLTFTTNLGDLAD-RQLV
MAB_0904|M.abscessus_ATCC_1997      RADAALQRVSAGLDRAAAKNRLAEA-PEHVLSRVDVVCSLTELPTDSELV
MSMEG_4110|M.smegmatis_MC2_155      AAEAAELRIIASLEKAEQLHTLPAP-MQVVKQRLTVDADPDALHG-CGLI
                                       *.  *:  .* :.     :.    . .   : .      *     *:

MMAR_0793|M.marinum_M               IEAIIEDEAVKTKVFADLDRVVTDPDAVLASNTSSIPIMKVAAATKNPRR
MUL_4537|M.ulcerans_Agy99           IEAIIEDEAVKTKVFADLDRVVTDPDAVLASNTSSIPIMKVAAATKNPRR
MAV_4681|M.avium_104                IEAIIEDDAVKAQVFAELDRVVTDPDAVLASNTSSIPIMKLAAATKNPQR
MLBr_02461|M.leprae_Br4923          IEAIVEDEAVKTKVFAELDRVITDPDAVLASNTSSIPIMKIAAATKNPQR
Mb0477|M.bovis_AF2122/97            IEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSIPIMKVAAATKQPQR
Rv0468|M.tuberculosis_H37Rv         IEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSIPIMKVAAATKQPQR
TH_3443|M.thermoresistible__bu      IEAIVEDENVKATVFAELDELLTDPDAVLASNTSSIPIMKLAAATKNPGR
Mflv_0106|M.gilvum_PYR-GCK          IEAIIEDEAVKAKVFAQLDEVVTDPDAVLASNTSSIPIMKIAAATKNPSR
Mvan_0802|M.vanbaalenii_PYR-1       IEAIVENEAVKAKVFAELDAVVTDPDAVLASNTSSIPIMKIAAATKNPSR
MAB_0904|M.abscessus_ATCC_1997      VEAVPENINLKIEVLGAAEKL-VEPTTVLASNTSSLSITELAAALLRPER
MSMEG_4110|M.smegmatis_MC2_155      VEAVPEVTELKAAVLALIEG--VAPHAVLATNTSSLSVDELATPLRQPTK
                                    :**: *   :*  ::.  :   . * :***:****:.: ::*:.  .* :

MMAR_0793|M.marinum_M               VLGLHFFNPVPVLPLVELVSTLVTDEAAVARTEEFASAVLGKQVVRCSDR
MUL_4537|M.ulcerans_Agy99           VLGLHFFNPVPVLPLVELVNTLVTDEAAVARTEEFASAVLGKQVVRCSDR
MAV_4681|M.avium_104                VLGLHFFNPVPVLPLVELVSTLVTDEAAAARTEEFASAVLGKQVVRCSDR
MLBr_02461|M.leprae_Br4923          VLGLHFFNPVPVLPLVELVSTLVTDEAAATRAEEFASGVLGKQVVRCSDR
Mb0477|M.bovis_AF2122/97            VLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVRCSDR
Rv0468|M.tuberculosis_H37Rv         VLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVRCSDR
TH_3443|M.thermoresistible__bu      VLGLHFFNPVPVLPLVELINTLVTTDEAIARTEKFAAEVLGKQVVRCGDR
Mflv_0106|M.gilvum_PYR-GCK          VLGLHFFNPVPVLPLVEVINTLVTSEEAVARVEQFASEVLGKKVVRCGDR
Mvan_0802|M.vanbaalenii_PYR-1       VLGLHFFNPVPVLPLVELVNTLVTSDDAIARVERFAGEVLGKKVVRCGDR
MAB_0904|M.abscessus_ATCC_1997      VVGMHFFNPVPTSQLVEIVRAPETSDDTVAAALAWVR-ALGKADVVARDS
MSMEG_4110|M.smegmatis_MC2_155      FLGLHFFNPVPASQLVEIVVGTKTADDVVATAHTWIK-SLDKTAITVKDA
                                    .:*:*******.  ***::    * : . : .  :    *.*  :   * 

MMAR_0793|M.marinum_M               SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MUL_4537|M.ulcerans_Agy99           SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MAV_4681|M.avium_104                SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
MLBr_02461|M.leprae_Br4923          SGFVVNALLVPYLLSAIRIVEAGFATVEDVDKAVLAGLSHPMGPLRLSDL
Mb0477|M.bovis_AF2122/97            SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
Rv0468|M.tuberculosis_H37Rv         SGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDL
TH_3443|M.thermoresistible__bu      SGFVVNALLVPYLLSAIRMVESGYASVEDVDKAVVAGLSHPMGPLRLSDL
Mflv_0106|M.gilvum_PYR-GCK          SGFIVNALLVPYLLSAIRMAEAGVATVEDIDTAVVAGLSHPMGPLRLSDL
Mvan_0802|M.vanbaalenii_PYR-1       SGFVVNALLVPYLLSAIRMAEAGVATVEDIDTAVVAGLSHPMGPLRLSDL
MAB_0904|M.abscessus_ATCC_1997      PGFASSRLGVALGLEAIRMLEEGVADAESIDRAMELGYRHPMGPLRSTDL
MSMEG_4110|M.smegmatis_MC2_155      PGFASSRLGVAIALEAMRMVEDDVASVADIDAAMTLGYKHPMGPLRTTDI
                                    .**  . * *.  *.*:*: * . * . .:* *:  *  ******* :*:

MMAR_0793|M.marinum_M               VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGQGFYTY--
MUL_4537|M.ulcerans_Agy99           VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGQGFYTY--
MAV_4681|M.avium_104                VGLDTLKLIADKMFEEFKEPQYGAPPLLLRMVEAGRLGKKTGQGFYTY--
MLBr_02461|M.leprae_Br4923          VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGLLGKKSGQGFYTY--
Mb0477|M.bovis_AF2122/97            VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY--
Rv0468|M.tuberculosis_H37Rv         VGLDTLKLIADKMFEEFKEPHYGPPPLLLRMVEAGQLGKKSGRGFYTY--
TH_3443|M.thermoresistible__bu      VGLDTLKLIADKMFDEFKEPHYGPPPLLVRMVEAGHLGKKTGRGFYTY--
Mflv_0106|M.gilvum_PYR-GCK          IGLDTMKLIADSMYDEYKDPNFAPPPLLQRMVEAGQLGKKSGKGFYSY--
Mvan_0802|M.vanbaalenii_PYR-1       IGLDTMKLIADSMYDEYKDPHYAPPPLLQRMVEAGQLGKKSGKGFYTY--
MAB_0904|M.abscessus_ATCC_1997      VGLDVRLAIAEHLCATLG-PRFTPPKLLRAKVAEGNLGRKTGQGFFRWSS
MSMEG_4110|M.smegmatis_MC2_155      VGLDVRLAIAEHLAHELG-PRFEPPAILRDKVAAGELGRKAGQGFYSW--
                                    :***.   **: :      *.: .* :*   *  * **:*:*:**: :

species	id	gene	e-value	identity (len)	annotation
M. abscessus ATCC 19977	MAB_0904	-	-	100% (289)	putative 3-hydroxyacyl-CoA dehydrogenase
M. abscessus ATCC 19977	MAB_4094c	-	2e-47	40.14% (284)	3-hydroxybutyryl-CoA dehydrogenase
M. abscessus ATCC 19977	MAB_4489c	-	3e-44	40.21% (281)	3-hydroxyacyl-CoA dehydrogenase family protein