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M. smegmatis MC2 155 MSMEG_4090 (-)

annotation: putative IclR family protein transcriptional regulator
coordinates: 4166046 - 4166819
length: 257

LADPDAEGRDAKSAYLLQRIAVILDCFTPETPQLRAIDICRTTDLPKSTVGRLLHNLAEENILERTGDYY
SIGLRVANWWSAASSNSDLTAIARPSLEWLRDQTNETCDVFARKGMTRILVAQARSTRSLLYSAQEGTVV
PLVSGASGKIFMAFDEGVREQALKHGLPQFTKQSITDAKRLDAELHLVRSRGWSFVEGEYEDDLNAVAAR
IFRGGDKELIGTAAIGAPATRLPPERAEQFGELTAHCARQISQRLLH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4090--100% (257)putative IclR family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_2507-2e-3432.49% (237) IclR-family protein transcriptional regulator
M. smegmatis MC2 155MSMEG_2025-6e-3230.20% (255) putative IclR family protein transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3013-5e-1125.25% (198) transcriptional regulatory protein
M. gilvum PYR-GCKMflv_3087-7e-1625.66% (226) transcriptional regulator, TrmB
M. tuberculosis H37RvRv2989-5e-1125.25% (198) transcriptional regulatory protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0077-6e-1327.03% (222) IclR family transcriptional regulator
M. marinum MMMAR_4423-6e-1627.36% (212) transcriptional regulatory protein
M. avium 104MAV_3839-5e-1324.66% (219) transcriptional regulator, IclR family protein
M. thermoresistible (build 8)TH_2042-6e-1526.03% (219) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN
M. ulcerans Agy99MUL_1967-2e-1124.77% (218) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_2134-2e-1526.48% (219) regulatory proteins, IclR

CLUSTAL 2.0.9 multiple sequence alignment


Mb3013|M.bovis_AF2122/97            --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
Rv2989|M.tuberculosis_H37Rv         --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
MUL_1967|M.ulcerans_Agy99           --------------------MRQDSGIGVIDKAVGLLRATAKS--PCGLA
MAV_3839|M.avium_104                ---------------------------------MGVLHTVAQS--PCGLA
TH_2042|M.thermoresistible__bu      --------------------MRKDSGIGVLDKAVSVLHSVAES--PCGLA
Mvan_2134|M.vanbaalenii_PYR-1       --------------------MRQNSGIGVLDKAVTVLHAVAES--PCGLA
Mflv_3087|M.gilvum_PYR-GCK          --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAHG-QAGVT
MMAR_4423|M.marinum_M               MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLG-KAGVT
MAB_0077|M.abscessus_ATCC_1997      ----------------MTITADSATPSAVIDRVSLLLDAFDGPG-RLTLA
MSMEG_4090|M.smegmatis_MC2_155      -------------MADPDAEGRDAKSAYLLQRIAVILDCFTPETPQLRAI
                                                                       :*             

Mb3013|M.bovis_AF2122/97            ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
Rv2989|M.tuberculosis_H37Rv         ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
MUL_1967|M.ulcerans_Agy99           ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVDD
MAV_3839|M.avium_104                ELCERTELPRATAYRLAAALEVHRLLARGDD-GRWRLGPAVTELAAHVND
TH_2042|M.thermoresistible__bu      ELCERTGLPRATAHRLAAGLEVHRLLARDGD-GRWCLGPAVTELAARVDD
Mvan_2134|M.vanbaalenii_PYR-1       DLCERTNLPRATAHRLAVGLEVHRLLAREGD-GQWRLGPALTELAGHVND
Mflv_3087|M.gilvum_PYR-GCK          EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG
MMAR_4423|M.marinum_M               EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
MAB_0077|M.abscessus_ATCC_1997      QLVRRTGLPRSSVHRMLERLVQLRWLRRDGR--DYELGTRLVELGSLAVH
MSMEG_4090|M.smegmatis_MC2_155      DICRTTDLPKSTVGRLLHNLAEENILERTGD--YYSIGLRVANWWSAASS
                                    ::     : :::. *:   *     : :      : :*  : .       

Mb3013|M.bovis_AF2122/97            P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
Rv2989|M.tuberculosis_H37Rv         P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
MUL_1967|M.ulcerans_Agy99           P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
MAV_3839|M.avium_104                P--LLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVP
TH_2042|M.thermoresistible__bu      P--LLAAAAVVLPRLREITGESVQLYRREGTSRICVAALEPPAGLRDTVP
Mvan_2134|M.vanbaalenii_PYR-1       P--LLAAGAVVLPRLRELTGESVQLYRREGTTRICIAALEPPAGLRDTVP
Mflv_3087|M.gilvum_PYR-GCK          QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW
MMAR_4423|M.marinum_M               HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
MAB_0077|M.abscessus_ATCC_1997      QDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATR
MSMEG_4090|M.smegmatis_MC2_155      NSDLTAIARPSLEWLRDQTNETCDVFARKGMTRILVAQARSTRSLLYSAQ
                                       *          *    .   .:   .    : :            . 

Mb3013|M.bovis_AF2122/97            VGARLPMTAGSGAKVLLAHTDAATQAAVLPK--AVFSAR----------A
Rv2989|M.tuberculosis_H37Rv         VGARLPMTAGSGAKVLLAHTDAATQAAVLPK--AVFSAR----------A
MUL_1967|M.ulcerans_Agy99           VGARLPMTAGSGAKVLLAHSDPATQQAVLPT--AKFTDR----------V
MAV_3839|M.avium_104                VGARLPMTAGSGAKVLLAHSDAATQKAVLAN--AKFTER----------T
TH_2042|M.thermoresistible__bu      VGTRLPMTAGSGAKVLLAYADSTTQQAVLSN--AKFSER----------A
Mvan_2134|M.vanbaalenii_PYR-1       VGIRLPMTAGSGAKVLLAYADAATQQAVLPG--AKFTDR----------T
Mflv_3087|M.gilvum_PYR-GCK          VGQSCPAYATSSGKVLLAGLDPAELPARIRPPLTEFTDSTLCGLAELQDE
MMAR_4423|M.marinum_M               VGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQ
MAB_0077|M.abscessus_ATCC_1997      IGGRQPAHCTASGKAILAYRAQILDGCTALARKTRYSIG---SAAQLRPE
MSMEG_4090|M.smegmatis_MC2_155      EGTVVPLVSGASGKIFMAFDEGVREQALKHG-LPQFTKQSITDAKRLDAE
                                     *   *  . :..* ::*                 ::             

Mb3013|M.bovis_AF2122/97            LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR
Rv2989|M.tuberculosis_H37Rv         LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR
MUL_1967|M.ulcerans_Agy99           LAEVRRRGWAQSVAEREPGVASVSAPVRD-GRGVVVAAISVSGPIDRIGR
MAV_3839|M.avium_104                LAEVRRRGWAQSVAEREPGVASVSAPVRD-SRGAVIAAISVSGPIDRIGR
TH_2042|M.thermoresistible__bu      LAEVHKRGWAQSVAEREPGVASVSAPVRD-GRGTVVAAVSVSGPIDRIGR
Mvan_2134|M.vanbaalenii_PYR-1       LAEVRRRGWAQSAAEREPGVASVSAPVRD-GRGAVVAAVSVSGPIDRMGR
Mflv_3087|M.gilvum_PYR-GCK          LAAVRERGWACVREELEVGLNAVAAPVYD-VHAQVIAALSVSGPSYRLAV
MMAR_4423|M.marinum_M               LAATRAAGWASAREELEIGLNAVAAPVYD-STGRVAAALSVSGPAYRLPA
MAB_0077|M.abscessus_ATCC_1997      LDKVRGHGVAFDREELQQGIGCVAAPIG--SIGDAVAAVSVCGPMTRMTF
MSMEG_4090|M.smegmatis_MC2_155      LHLVRSRGWSFVEGEYEDDLNAVAARIFRGGDKELIGTAAIGAPATRLPP
                                    *  .   * :    * : .: .*:* :         .: :: .*  *:  

Mb3013|M.bovis_AF2122/97            RP---------------GVRWAADLLSAADALTRRL--------------
Rv2989|M.tuberculosis_H37Rv         RP---------------GVRWAADLLSAADALTRRL--------------
MUL_1967|M.ulcerans_Agy99           RP---------------GARWAADLLAAADELARRL--------------
MAV_3839|M.avium_104                RP---------------GARWAADLVSAAEALTRRL--------------
TH_2042|M.thermoresistible__bu      RP---------------GARWAADLLAAAEALTRRL--------------
Mvan_2134|M.vanbaalenii_PYR-1       RP---------------GARWAADLVAAADALTRRL--------------
Mflv_3087|M.gilvum_PYR-GCK          DR---------------FDEVAKQTVAAAEQISRRLGWTTRN--------
MMAR_4423|M.marinum_M               AD---------------FEEVAQQTIAAADAVSRGLGWTDRIS-------
MAB_0077|M.abscessus_ATCC_1997      DQRLAAPVRMTAMGIWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMN
MSMEG_4090|M.smegmatis_MC2_155      ER---------------AEQFGELTAHCARQISQRLLH------------
                                                       . .      :    : *              

Mb3013|M.bovis_AF2122/97            -------
Rv2989|M.tuberculosis_H37Rv         -------
MUL_1967|M.ulcerans_Agy99           -------
MAV_3839|M.avium_104                -------
TH_2042|M.thermoresistible__bu      -------
Mvan_2134|M.vanbaalenii_PYR-1       -------
Mflv_3087|M.gilvum_PYR-GCK          -------
MMAR_4423|M.marinum_M               -------
MAB_0077|M.abscessus_ATCC_1997      SPALQYA
MSMEG_4090|M.smegmatis_MC2_155      -------