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LADPDAEGRDAKSAYLLQRIAVILDCFTPETPQLRAIDICRTTDLPKSTVGRLLHNLAEENILERTGDYY SIGLRVANWWSAASSNSDLTAIARPSLEWLRDQTNETCDVFARKGMTRILVAQARSTRSLLYSAQEGTVV PLVSGASGKIFMAFDEGVREQALKHGLPQFTKQSITDAKRLDAELHLVRSRGWSFVEGEYEDDLNAVAAR IFRGGDKELIGTAAIGAPATRLPPERAEQFGELTAHCARQISQRLLH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_4090 | - | - | 100% (257) | putative IclR family protein transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_2507 | - | 2e-34 | 32.49% (237) | IclR-family protein transcriptional regulator |
M. smegmatis MC2 155 | MSMEG_2025 | - | 6e-32 | 30.20% (255) | putative IclR family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3013 | - | 5e-11 | 25.25% (198) | transcriptional regulatory protein |
M. gilvum PYR-GCK | Mflv_3087 | - | 7e-16 | 25.66% (226) | transcriptional regulator, TrmB |
M. tuberculosis H37Rv | Rv2989 | - | 5e-11 | 25.25% (198) | transcriptional regulatory protein |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0077 | - | 6e-13 | 27.03% (222) | IclR family transcriptional regulator |
M. marinum M | MMAR_4423 | - | 6e-16 | 27.36% (212) | transcriptional regulatory protein |
M. avium 104 | MAV_3839 | - | 5e-13 | 24.66% (219) | transcriptional regulator, IclR family protein |
M. thermoresistible (build 8) | TH_2042 | - | 6e-15 | 26.03% (219) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
M. ulcerans Agy99 | MUL_1967 | - | 2e-11 | 24.77% (218) | transcriptional regulatory protein |
M. vanbaalenii PYR-1 | Mvan_2134 | - | 2e-15 | 26.48% (219) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment Mb3013|M.bovis_AF2122/97 --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA Rv2989|M.tuberculosis_H37Rv --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKS--PCGLA MAV_3839|M.avium_104 ---------------------------------MGVLHTVAQS--PCGLA TH_2042|M.thermoresistible__bu --------------------MRKDSGIGVLDKAVSVLHSVAES--PCGLA Mvan_2134|M.vanbaalenii_PYR-1 --------------------MRQNSGIGVLDKAVTVLHAVAES--PCGLA Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAHG-QAGVT MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLG-KAGVT MAB_0077|M.abscessus_ATCC_1997 ----------------MTITADSATPSAVIDRVSLLLDAFDGPG-RLTLA MSMEG_4090|M.smegmatis_MC2_155 -------------MADPDAEGRDAKSAYLLQRIAVILDCFTPETPQLRAI :* Mb3013|M.bovis_AF2122/97 ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD Rv2989|M.tuberculosis_H37Rv ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVDD MAV_3839|M.avium_104 ELCERTELPRATAYRLAAALEVHRLLARGDD-GRWRLGPAVTELAAHVND TH_2042|M.thermoresistible__bu ELCERTGLPRATAHRLAAGLEVHRLLARDGD-GRWCLGPAVTELAARVDD Mvan_2134|M.vanbaalenii_PYR-1 DLCERTNLPRATAHRLAVGLEVHRLLAREGD-GQWRLGPALTELAGHVND Mflv_3087|M.gilvum_PYR-GCK EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG MAB_0077|M.abscessus_ATCC_1997 QLVRRTGLPRSSVHRMLERLVQLRWLRRDGR--DYELGTRLVELGSLAVH MSMEG_4090|M.smegmatis_MC2_155 DICRTTDLPKSTVGRLLHNLAEENILERTGD--YYSIGLRVANWWSAASS :: : :::. *: * : : : :* : . Mb3013|M.bovis_AF2122/97 P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP Rv2989|M.tuberculosis_H37Rv P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP MUL_1967|M.ulcerans_Agy99 P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP MAV_3839|M.avium_104 P--LLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVP TH_2042|M.thermoresistible__bu P--LLAAAAVVLPRLREITGESVQLYRREGTSRICVAALEPPAGLRDTVP Mvan_2134|M.vanbaalenii_PYR-1 P--LLAAGAVVLPRLRELTGESVQLYRREGTTRICIAALEPPAGLRDTVP Mflv_3087|M.gilvum_PYR-GCK QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW MAB_0077|M.abscessus_ATCC_1997 QDRLHAAALPMLHELHRATGLVVHLSILDGADVVYLEKIGAGIGAAVATR MSMEG_4090|M.smegmatis_MC2_155 NSDLTAIARPSLEWLRDQTNETCDVFARKGMTRILVAQARSTRSLLYSAQ * * . .: . : : . Mb3013|M.bovis_AF2122/97 VGARLPMTAGSGAKVLLAHTDAATQAAVLPK--AVFSAR----------A Rv2989|M.tuberculosis_H37Rv VGARLPMTAGSGAKVLLAHTDAATQAAVLPK--AVFSAR----------A MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDPATQQAVLPT--AKFTDR----------V MAV_3839|M.avium_104 VGARLPMTAGSGAKVLLAHSDAATQKAVLAN--AKFTER----------T TH_2042|M.thermoresistible__bu VGTRLPMTAGSGAKVLLAYADSTTQQAVLSN--AKFSER----------A Mvan_2134|M.vanbaalenii_PYR-1 VGIRLPMTAGSGAKVLLAYADAATQQAVLPG--AKFTDR----------T Mflv_3087|M.gilvum_PYR-GCK VGQSCPAYATSSGKVLLAGLDPAELPARIRPPLTEFTDSTLCGLAELQDE MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQ MAB_0077|M.abscessus_ATCC_1997 IGGRQPAHCTASGKAILAYRAQILDGCTALARKTRYSIG---SAAQLRPE MSMEG_4090|M.smegmatis_MC2_155 EGTVVPLVSGASGKIFMAFDEGVREQALKHG-LPQFTKQSITDAKRLDAE * * . :..* ::* :: Mb3013|M.bovis_AF2122/97 LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR Rv2989|M.tuberculosis_H37Rv LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR MUL_1967|M.ulcerans_Agy99 LAEVRRRGWAQSVAEREPGVASVSAPVRD-GRGVVVAAISVSGPIDRIGR MAV_3839|M.avium_104 LAEVRRRGWAQSVAEREPGVASVSAPVRD-SRGAVIAAISVSGPIDRIGR TH_2042|M.thermoresistible__bu LAEVHKRGWAQSVAEREPGVASVSAPVRD-GRGTVVAAVSVSGPIDRIGR Mvan_2134|M.vanbaalenii_PYR-1 LAEVRRRGWAQSAAEREPGVASVSAPVRD-GRGAVVAAVSVSGPIDRMGR Mflv_3087|M.gilvum_PYR-GCK LAAVRERGWACVREELEVGLNAVAAPVYD-VHAQVIAALSVSGPSYRLAV MMAR_4423|M.marinum_M LAATRAAGWASAREELEIGLNAVAAPVYD-STGRVAAALSVSGPAYRLPA MAB_0077|M.abscessus_ATCC_1997 LDKVRGHGVAFDREELQQGIGCVAAPIG--SIGDAVAAVSVCGPMTRMTF MSMEG_4090|M.smegmatis_MC2_155 LHLVRSRGWSFVEGEYEDDLNAVAARIFRGGDKELIGTAAIGAPATRLPP * . * : * : .: .*:* : .: :: .* *: Mb3013|M.bovis_AF2122/97 RP---------------GVRWAADLLSAADALTRRL-------------- Rv2989|M.tuberculosis_H37Rv RP---------------GVRWAADLLSAADALTRRL-------------- MUL_1967|M.ulcerans_Agy99 RP---------------GARWAADLLAAADELARRL-------------- MAV_3839|M.avium_104 RP---------------GARWAADLVSAAEALTRRL-------------- TH_2042|M.thermoresistible__bu RP---------------GARWAADLLAAAEALTRRL-------------- Mvan_2134|M.vanbaalenii_PYR-1 RP---------------GARWAADLVAAADALTRRL-------------- Mflv_3087|M.gilvum_PYR-GCK DR---------------FDEVAKQTVAAAEQISRRLGWTTRN-------- MMAR_4423|M.marinum_M AD---------------FEEVAQQTIAAADAVSRGLGWTDRIS------- MAB_0077|M.abscessus_ATCC_1997 DQRLAAPVRMTAMGIWRNVENGPSRVAPTLQPIRPLRCGPAASSTGREMN MSMEG_4090|M.smegmatis_MC2_155 ER---------------AEQFGELTAHCARQISQRLLH------------ . . : : * Mb3013|M.bovis_AF2122/97 ------- Rv2989|M.tuberculosis_H37Rv ------- MUL_1967|M.ulcerans_Agy99 ------- MAV_3839|M.avium_104 ------- TH_2042|M.thermoresistible__bu ------- Mvan_2134|M.vanbaalenii_PYR-1 ------- Mflv_3087|M.gilvum_PYR-GCK ------- MMAR_4423|M.marinum_M ------- MAB_0077|M.abscessus_ATCC_1997 SPALQYA MSMEG_4090|M.smegmatis_MC2_155 -------