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MAKGDGESGKQQTLLVLTKIVEILNAFTLTRPAMTLGEIQQATGLPTSTVQRLVSNMVAQGMLDRVGEQI RIGIRMSYWAATARKDLDVLAIVTPVLKEIRDKIGETACFFTVEQNFRVCVAVAETHHALRRHMYVGKVI PLHVGSASRVLLAWNPELAERILSAPLEPLTEGTVTSAEDLAALIAKARADGYAITTGEREDSASGLSAP VFDSAGDVLGALTISGPTVRMPLEKCEEWVDLVVGYAEQITRSLGGRPPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2025 | - | - | 100% (260) | putative IclR family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_2507 | - | 1e-32 | 29.58% (240) | IclR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4090 | - | 6e-32 | 30.20% (255) | putative IclR family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3013 | - | 1e-18 | 30.13% (239) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4228 | - | 2e-19 | 29.58% (240) | regulatory protein, IclR |
| M. tuberculosis H37Rv | Rv2989 | - | 1e-18 | 30.13% (239) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3295 | - | 7e-22 | 31.54% (241) | IclR family transcriptional regulator |
| M. marinum M | MMAR_4423 | - | 3e-23 | 29.28% (222) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 5e-20 | 31.58% (228) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_2042 | - | 1e-21 | 28.98% (245) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_1967 | - | 1e-19 | 29.58% (240) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_2134 | - | 2e-20 | 30.42% (240) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3013|M.bovis_AF2122/97 --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
Rv2989|M.tuberculosis_H37Rv --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKS--PCGLA
MAV_3839|M.avium_104 ---------------------------------MGVLHTVAQS--PCGLA
Mflv_4228|M.gilvum_PYR-GCK --------------------MRQNSGIGVLDKAITVLHAVAES--PCGLA
Mvan_2134|M.vanbaalenii_PYR-1 --------------------MRQNSGIGVLDKAVTVLHAVAES--PCGLA
TH_2042|M.thermoresistible__bu --------------------MRKDSGIGVLDKAVSVLHSVAES--PCGLA
MAB_3295|M.abscessus_ATCC_1997 --------------------MRQHSGIGVLDKAVQVLTAIGDS--PCGLA
MMAR_4423|M.marinum_M MSSGISSMIMGTGNDGGASESDPAPTVQSVDRALLVLELLADLG-KAGVT
MSMEG_2025|M.smegmatis_MC2_155 -------------MAKGDGESGKQQTLLVLTKIVEILNAFTLTRPAMTLG
: :* :
Mb3013|M.bovis_AF2122/97 ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVD-
Rv2989|M.tuberculosis_H37Rv ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVD-
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVD-
MAV_3839|M.avium_104 ELCERTELPRATAYRLAAALEVHRLLARGDD-GRWRLGPAVTELAAHVN-
Mflv_4228|M.gilvum_PYR-GCK DLCERTDLPRATAHRLAVGLEVHRLLARDGD-GLWRLGPALTELAGHVN-
Mvan_2134|M.vanbaalenii_PYR-1 DLCERTNLPRATAHRLAVGLEVHRLLAREGD-GQWRLGPALTELAGHVN-
TH_2042|M.thermoresistible__bu ELCERTGLPRATAHRLAAGLEVHRLLARDGD-GRWCLGPAVTELAARVD-
MAB_3295|M.abscessus_ATCC_1997 ELCERTGLPRATAHRLAAGLEVHRLLSRDGD-GQWQLGAGLTELAAHVN-
MMAR_4423|M.marinum_M EVADELGVHKSTASRLITALEARGYVEQLSDRGKYQLGIGVSRLARARSG
MSMEG_2025|M.smegmatis_MC2_155 EIQQATGLPTSTVQRLVSNMVAQGMLDRVGE--QIRIGIRMSYWAATARK
:: : : :*. ** : .: : : : :* :: *
Mb3013|M.bovis_AF2122/97 -DPLLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
Rv2989|M.tuberculosis_H37Rv -DPLLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
MUL_1967|M.ulcerans_Agy99 -DPLLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
MAV_3839|M.avium_104 -DPLLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVP
Mflv_4228|M.gilvum_PYR-GCK -DSLLAAGAVVLPRLRELTGESVQLYRREGTSRICVAALEPPAGLRDTVP
Mvan_2134|M.vanbaalenii_PYR-1 -DPLLAAGAVVLPRLRELTGESVQLYRREGTTRICIAALEPPAGLRDTVP
TH_2042|M.thermoresistible__bu -DPLLAAAAVVLPRLREITGESVQLYRREGTSRICVAALEPPAGLRDTVP
MAB_3295|M.abscessus_ATCC_1997 -DPLLSASAQVLPKLREITGESVQLYRREGTVRICVAALEPPAGLRDTVP
MMAR_4423|M.marinum_M HSDLVKLSQDACDKLAADLGETANLAILDENRAVNIVEAVSTAEIALQTW
MSMEG_2025|M.smegmatis_MC2_155 DLDVLAIVTPVLKEIRDKIGETACFFTVEQNFRVCVAVAETHHALRRHMY
:: . : **:. . : . : :. . :
Mb3013|M.bovis_AF2122/97 VGARLPMTAGSGAKVLLA--HTDAATQAAVLPKAVFSAR----------A
Rv2989|M.tuberculosis_H37Rv VGARLPMTAGSGAKVLLA--HTDAATQAAVLPKAVFSAR----------A
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLA--HSDPATQQAVLPTAKFTDR----------V
MAV_3839|M.avium_104 VGARLPMTAGSGAKVLLA--HSDAATQKAVLANAKFTER----------T
Mflv_4228|M.gilvum_PYR-GCK VGTRLSMTAGSGAKVLLA--YADTHTQQAVLPNAKFTDR----------T
Mvan_2134|M.vanbaalenii_PYR-1 VGIRLPMTAGSGAKVLLA--YADAATQQAVLPGAKFTDR----------T
TH_2042|M.thermoresistible__bu VGTRLPMTAGSGAKVLLA--YADSTTQQAVLSNAKFSER----------A
MAB_3295|M.abscessus_ATCC_1997 VGSRLPMSAGSGAKVLLA--HSDPGTQAAVLPGATFTER----------A
MMAR_4423|M.marinum_M VGQSCPVHATSSGKVLLAGLDADEVRQRVGATLDSFTENTIVTIDALEAQ
MSMEG_2025|M.smegmatis_MC2_155 VGKVIPLHVGSASRVLLA-WNPELAERILSAPLEPLTEGTVTSAEDLAAL
** .: . *..:**** .: : . ::
Mb3013|M.bovis_AF2122/97 LAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAAISVSGPIDRMGRR
Rv2989|M.tuberculosis_H37Rv LAEVCRRGWAQSVAEREPGVASVSAPVRDGRGVVIAAISVSGPIDRMGRR
MUL_1967|M.ulcerans_Agy99 LAEVRRRGWAQSVAEREPGVASVSAPVRDGRGVVVAAISVSGPIDRIGRR
MAV_3839|M.avium_104 LAEVRRRGWAQSVAEREPGVASVSAPVRDSRGAVIAAISVSGPIDRIGRR
Mflv_4228|M.gilvum_PYR-GCK LAEVRKRGWAQSAAEREPGVASVSAPVRDGRGAVIAAVSVSGPIDRMGRR
Mvan_2134|M.vanbaalenii_PYR-1 LAEVRRRGWAQSAAEREPGVASVSAPVRDGRGAVVAAVSVSGPIDRMGRR
TH_2042|M.thermoresistible__bu LAEVHKRGWAQSVAEREPGVASVSAPVRDGRGTVVAAVSVSGPIDRIGRR
MAB_3295|M.abscessus_ATCC_1997 LADVRKRGWAQSAAEREAGVASVSAPVRDRHGNVIAAISVSGPIDRMGRR
MMAR_4423|M.marinum_M LAATRAAGWASAREELEIGLNAVAAPVYDSTGRVAAALSVSGPAYRLPAA
MSMEG_2025|M.smegmatis_MC2_155 IAKARADGYAITTGEREDSASGLSAPVFDSAGDVLGALTISGPTVRMPLE
:* . *:* : * * . .::*** * * * .*:::*** *:
Mb3013|M.bovis_AF2122/97 PGVRWAADLLSAADALTRRL-------
Rv2989|M.tuberculosis_H37Rv PGVRWAADLLSAADALTRRL-------
MUL_1967|M.ulcerans_Agy99 PGARWAADLLAAADELARRL-------
MAV_3839|M.avium_104 PGARWAADLVSAAEALTRRL-------
Mflv_4228|M.gilvum_PYR-GCK PGARWAADLVAAADALTRRL-------
Mvan_2134|M.vanbaalenii_PYR-1 PGARWAADLVAAADALTRRL-------
TH_2042|M.thermoresistible__bu PGARWAADLLAAAEALTRRL-------
MAB_3295|M.abscessus_ATCC_1997 PGARWAADLVAASEAITARL-------
MMAR_4423|M.marinum_M DFEEVAQQTIAAADAVSRGLGWTDRIS
MSMEG_2025|M.smegmatis_MC2_155 KCEEWVDLVVGYAEQITRSLGGRPPA-
. . :. :: :: *