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MIASTKKITIVGATGLIGRQLTPLLREAGHDVTEASRASGTDLVTGEGLDVALTDADVVVDVINSATPDD SAEKFFKQTSANLSAAAAQAGVGHYVVLSIVGVDAMAANAGYIRGKLAQESAAAKSGIPWTVVRATQFHE LAEPITESLITGEQVRAPKALIQTIDSKEVTAILARIATGSPFNAIHNLGGPQKMTFADMARAVLVHQSR ELEVIDDPAATYQGLPVDNTTLVTDDEAELGTTRLSDWLALH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4056 | - | - | 100% (252) | hypothetical protein MSMEG_4056 |
| M. smegmatis MC2 155 | MSMEG_2353 | - | 2e-66 | 53.47% (245) | secreted protein |
| M. smegmatis MC2 155 | MSMEG_4426 | - | 3e-48 | 42.11% (247) | secreted protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2239 | - | 1e-05 | 31.85% (135) | hypothetical protein Mb2239 |
| M. gilvum PYR-GCK | Mflv_1635 | - | 5e-06 | 25.23% (218) | NAD-dependent epimerase/dehydratase |
| M. tuberculosis H37Rv | Rv2216 | - | 1e-05 | 31.85% (135) | hypothetical protein Rv2216 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3360c | - | 5e-60 | 49.80% (245) | hypothetical protein MAB_3360c |
| M. marinum M | MMAR_4766 | - | 1e-40 | 40.32% (248) | hypothetical protein MMAR_4766 |
| M. avium 104 | MAV_4078 | - | 9e-17 | 30.58% (206) | hypothetical protein MAV_4078 |
| M. thermoresistible (build 8) | TH_3570 | - | 9e-60 | 50.20% (245) | PUTATIVE secreted protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2101 | - | 3e-61 | 50.83% (242) | dTDP-4-dehydrorhamnose reductase |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3360c|M.abscessus_ATCC_199 -----MKITVVGATGQIGSRVVSLLIADGHDVVAASLSSGAN--------
Mvan_2101|M.vanbaalenii_PYR-1 -----MKISVIGATGLIGSKVVDLLQRDGHHVVAASRASGAD--------
TH_3570|M.thermoresistible__bu VEGAVMRITVFGATGRIGSEVVALLRADGHDVVPASLSTGAD--------
MMAR_4766|M.marinum_M -----MKILVIGGSGLIGSQVVAQLTGLAHQAVAASPRSGVN--------
MSMEG_4056|M.smegmatis_MC2_155 MIASTKKITIVGATGLIGRQLTPLLREAGHDVTEASRASGTD--------
MAV_4078|M.avium_104 -MRALTTIAVIGATGTAGSRVVARLRPRDVAVVEISRAQGVD--------
Mb2239|M.bovis_AF2122/97 --MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANS-------
Rv2216|M.tuberculosis_H37Rv --MANAVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANS-------
Mflv_1635|M.gilvum_PYR-GCK MPGNDVRCVVTGATGYIGGRLVPELLARGLQVRAMARTPSKLDRTEWRDR
: *.:* * :. * .
MAB_3360c|M.abscessus_ATCC_199 -------VLTGEGLVDALTGSAVVIDVVNSPSFEDGP-------VMDFFT
Mvan_2101|M.vanbaalenii_PYR-1 -------VLTGEGLTDALAGADVLVDVTNSPSFDDDA-------VMDFFT
TH_3570|M.thermoresistible__bu -------VVTGAGLADSLSGADVLVDVVNSPSFADGP-------VSEFFT
MMAR_4766|M.marinum_M -------ALTGEGLADAVAGADAVVDVSNSPSFADDD-------VLHFFT
MSMEG_4056|M.smegmatis_MC2_155 -------LVTGEGLDVALTDADVVVDVINS-ATPDDS-------AEKFFK
MAV_4078|M.avium_104 -------VFDAPGLTRALEGVDVVIDVSNPVPPDGRSD------IRQTLA
Mb2239|M.bovis_AF2122/97 -EELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRI
Rv2216|M.tuberculosis_H37Rv -EELHWNPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRI
Mflv_1635|M.gilvum_PYR-GCK VEVVRGDLTEADSLTAAFNGADVVYYLVHSMGTSRDF--------VAEER
. :. . .: :
MAB_3360c|M.abscessus_ATCC_199 ASARNLVDAAKATGVGHYVALSIVG---------ADG-LPE-SGYMRAKV
Mvan_2101|M.vanbaalenii_PYR-1 RSSANLVSAAEESGVRHYVALSIVG---------ADG-LPE-SGYMRAKV
TH_3570|M.thermoresistible__bu AAALNLTAAARAAGVGHHVALSIVG---------CDE-LPD-SGYMRAKA
MMAR_4766|M.marinum_M TSTKNLLAAEQTAGVRHHVALSIVG---------TDR-VPN-SGYLRAKC
MSMEG_4056|M.smegmatis_MC2_155 QTSANLSAAAAQAGVGHYVVLSIVG---------VDA-MAANAGYIRGKL
MAV_4078|M.avium_104 TAARNIMGACATQEVQRLVVLTIAG---------IEDPVFDEFPYYQAKR
Mb2239|M.bovis_AF2122/97 TPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLC
Rv2216|M.tuberculosis_H37Rv TPTEVLSAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLC
Mflv_1635|M.gilvum_PYR-GCK RSAHNVVEAAKKAGVRRIVYLSGLH---------PDR--KELSRHLASRV
.: : * * : : : .
MAB_3360c|M.abscessus_ATCC_199 AQEKIIVGSG--------LPYTIVRATQFQEFAEAITDTLVVGDEVRVPD
Mvan_2101|M.vanbaalenii_PYR-1 VQEKTIAGSD--------VPHSIVRATQFHEFADAIVGTLEADDEVRVPD
TH_3570|M.thermoresistible__bu AQERIIAESG--------LPYTIVRATQFDEFAEAIVESLIVGAEVRVPD
MMAR_4766|M.marinum_M AQEKLIKESD--------LPYSIVRATQFFEFVIGIADSATDGDTVRLSH
MSMEG_4056|M.smegmatis_MC2_155 AQESAAAKSG--------IPWTVVRATQFHELAEPITESLITGEQVRAPK
MAV_4078|M.avium_104 EAKEILLDGP--------VPTTVVKSTQWYEFATNHDAVSCDDNEVIVED
Mb2239|M.bovis_AF2122/97 VDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGS
Rv2216|M.tuberculosis_H37Rv VDWETATRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGS
Mflv_1635|M.gilvum_PYR-GCK EVGEILMQSG-IETVVLQAGIVIGSGSASFEMVRHLTDRLPVMTTPKWVH
: :
MAB_3360c|M.abscessus_ATCC_199 --ARIQLIAVDDVSTQVAHAAAAAP-RNGIINIGGPEKFSFADMAGAVLA
Mvan_2101|M.vanbaalenii_PYR-1 --ARIQPIAADDVAAEVFRAAVGSP-VDGVINIGGPDKISFADLARAVLA
TH_3570|M.thermoresistible__bu --GSIQPIAAADVAAEVAARAVAEP-AGGVVNIGGPDRMSFADLARTVLA
MMAR_4766|M.marinum_M T-AAIQPIAASDVATGVTRAAISDP-LNGTTNIAGPDKFGMDDFVRMGLA
MSMEG_4056|M.smegmatis_MC2_155 --ALIQTIDSKEVTAILARIATGSP-FNAIHNLGGPQKMTFADMARAVLV
MAV_4078|M.avium_104 --WLIQPIAADTVADVLVETALAQT-HTPRT-ITGPDAIRLPELTSKLLV
Mb2239|M.bovis_AF2122/97 GRQYMSWISLEDEVRALQFAIAQPN-LSGPVNLTGPAPVTNAEFTTAFGR
Rv2216|M.tuberculosis_H37Rv GRQYMSWISLEDEVRALQFAIAQPN-LSGPVNLTGPAPVTNAEFTTAFGR
Mflv_1635|M.gilvum_PYR-GCK N--KIQPISISDVLHYLAEAATAEFGESRTWDIGGPDVMEYGDAMQGYAD
:. * : : ** . :
MAB_3360c|M.abscessus_ATCC_199 ARGDDRPVV-VDSGAT------YFGT---PVDDFS--LVT--GDDGVLTQ
Mvan_2101|M.vanbaalenii_PYR-1 RRGADKTVV-IDPQAT------YFGT---PLDQNS--LVT--GDGAVLGA
TH_3570|M.thermoresistible__bu HQHRRTPVV-IDPQAT------YFGT---RIDDTS--LVT--GAGAVIAG
MMAR_4766|M.marinum_M AHGDSRQVR-TDPNAR------YFGA---VLDGHS--IVPTDGEDVTIYP
MSMEG_4056|M.smegmatis_MC2_155 HQSRELEVI-DDPAAT------YQGL---PVDNTT--LVT--DDEAELGT
MAV_4078|M.avium_104 RQGDRRAVRSVEPAVS------ALGAGALLASGHA--VVVGPDVDTWLQT
Mb2239|M.bovis_AF2122/97 AVNRPTPLM--LPSVA------VRAAFGEFADEGL--LIGQRAIPSALER
Rv2216|M.tuberculosis_H37Rv AVNRPTPLM--LPSVA------VRAAFGEFADEGL--LIGQRAIPSALER
Mflv_1635|M.gilvum_PYR-GCK VAGLRRRVMVVLPFLTPTIASWWVGLVTPIPSGLARPLVESLECDAICHE
: . . . ::
MAB_3360c|M.abscessus_ATCC_199 TRFADWMARR-------------------------------------
Mvan_2101|M.vanbaalenii_PYR-1 VRFADHH----------------------------------------
TH_3570|M.thermoresistible__bu TPLAAVLAPPASD----------------------------------
MMAR_4766|M.marinum_M THFSDWLAAG-------------------------------------
MSMEG_4056|M.smegmatis_MC2_155 TRLSDWLALH-------------------------------------
MAV_4078|M.avium_104 LAPPGGDGHRGRDGDGHRGADGDHRGADGDGKPRRG-----------
Mb2239|M.bovis_AF2122/97 AGFQFHHNTIGEALGYATTRPG-------------------------
Rv2216|M.tuberculosis_H37Rv AGFQFHHNTIGEALGYATTRPG-------------------------
Mflv_1635|M.gilvum_PYR-GCK HDIDAVIPPPKGGLIGYREAVAKELRSEGGSSAGRRHLLRFSPAASD