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TKSTVLLAITRGVGWLRLNRADKRNALSQQLISDLNAALDQIENDPSCRVIVVTGMGPAFSAGGDLREFK QFLDRGDREGLVRFVDHTAKTLSRLEDSPRPVIAAVNGVAVAGGMELLLCCDIVLAADTALIGDGHARYG VLPGAGGVARLVNKVPPNIAARLLLSGELLPAGHRHLTGLVDEVVPHDELIGVAGKLAAHIADLSPLALA HMKRTAHSARNQPVSVGLGLELTTFGDYIGSRDFAEGMSAFSEHRAPVFTGQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4020 | - | - | 100% (263) | enoyl-CoA hydratase/isomerase family protein |
| M. smegmatis MC2 155 | MSMEG_5277 | - | 3e-35 | 36.19% (257) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_6777 | - | 5e-34 | 36.95% (249) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 2e-38 | 35.63% (261) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2036 | - | 1e-33 | 35.63% (261) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 2e-38 | 35.63% (261) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 2e-33 | 33.98% (259) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2058 | - | 6e-32 | 34.98% (263) | enoyl-CoA dehydratase/isomerase |
| M. marinum M | MMAR_4396 | echA8 | 6e-35 | 33.59% (259) | enoyl-CoA hydratase EchA8 |
| M. avium 104 | MAV_1195 | - | 1e-36 | 36.15% (260) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4102 | - | 2e-36 | 36.19% (257) | PUTATIVE short chain enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 4e-35 | 33.59% (259) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1871 | - | 2e-32 | 38.60% (215) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4020|M.smegmatis_MC2_155 ------MTKSTVLLAITRGVGWLRLNRADKRNALSQQLISDLNAALDQIE
MAB_2058|M.abscessus_ATCC_1997 ------MAEQPIRYEVVDSVAWLTINRPEARNALNNAVRTGLIDAVLRFN
MMAR_4396|M.marinum_M ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MUL_0210|M.ulcerans_Agy99 ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
Mb1099c|M.bovis_AF2122/97 ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
Rv1070c|M.tuberculosis_H37Rv ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
MLBr_02402|M.leprae_Br4923 ------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELD
MAV_1195|M.avium_104 MTDSTDRTFETILVEREERVGIITLNRPKALNALNTQVMNEVTTAATDFD
Mflv_2036|M.gilvum_PYR-GCK ------MTFETILVDRDDRVATITLNRPKALNALNTQVMNEVTTAAAELD
TH_4102|M.thermoresistible__bu ---MSAKNYETILVTREDRVGIITLNRPKALNALNSQVMTEVTDAAAEFD
Mvan_1871|M.vanbaalenii_PYR-1 ------MTAELVLTADHDGVRVITLNRPAARNALSRDLIRASYAALTAAD
. : * : :**. ***. : * :
MSMEG_4020|M.smegmatis_MC2_155 NDPSCRVIVVTGMG-PAFSAGGDLREFKQFLDRGDREGLVRFVDHTAKTL
MAB_2058|M.abscessus_ATCC_1997 DDDAAKVLVLTGVGDKAFCAGGDLKEMAQN-------ALKVPPKDFAPQF
MMAR_4396|M.marinum_M NDPGIGAIIITGSA-KAFAAGADIKEMADLT------FSEAFDADFFAAW
MUL_0210|M.ulcerans_Agy99 NDPGIGAIIITGSA-KAFAAGADIKEMADLT------FSEAFDADFFAAW
Mb1099c|M.bovis_AF2122/97 DDPDIGAIIITGSA-KAFAAGADIKEMADLT------FADAFTADFFATW
Rv1070c|M.tuberculosis_H37Rv DDPDIGAIIITGSA-KAFAAGADIKEMADLT------FADAFTADFFATW
MLBr_02402|M.leprae_Br4923 IDPDVGAILITGSP-KVFAAGADIKEMASLT------FTDAFDADFFSAW
MAV_1195|M.avium_104 ADPGIGAIIITGSA-KAFAAGADIKEMAELT------FADAYGADFFAPW
Mflv_2036|M.gilvum_PYR-GCK AEPGVGAIIVTGSE-RAFAAGADIKEMASLS------FADVFSSDFFAAW
TH_4102|M.thermoresistible__bu SDPGIGAIIVTGNE-KAFAAGADIKEMADLE------FADVFAADFFAPW
Mvan_1871|M.vanbaalenii_PYR-1 ADESVRAVVLTGAD-PAFCAGVDLKEAARDG------LSYFAEFRSQSCI
: .:::** .*.** *::*
MSMEG_4020|M.smegmatis_MC2_155 SRLEDSPRPVIAAVNGVAVAGGMELLLCCDIVLAADTALIGDGHARYGVL
MAB_2058|M.abscessus_ATCC_1997 GRNIDVAKPTIAAVNGVAFAGGFLLAQQCDLVVAAEHATFAVSEVKVG--
MMAR_4396|M.marinum_M GKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVL
MUL_0210|M.ulcerans_Agy99 GKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVL
Mb1099c|M.bovis_AF2122/97 GKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVL
Rv1070c|M.tuberculosis_H37Rv GKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVL
MLBr_02402|M.leprae_Br4923 GKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVL
MAV_1195|M.avium_104 GKLAALRTPTIAAVAGHALGGGCELAMMCDVLIAADTAKFGQPEIKLGVL
Mflv_2036|M.gilvum_PYR-GCK GKFAATRTPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVL
TH_4102|M.thermoresistible__bu SKFAATRTPTIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVL
Mvan_1871|M.vanbaalenii_PYR-1 AAVARMRTPVVGAINGATFTGGLEMALGCDFLIASERAVFADTHARVGIL
. * :.*: * :. ** : **.::*:: * :. . : *
MSMEG_4020|M.smegmatis_MC2_155 PGAGGVARLVNKVPPNIAARLLLSGELLPAGHRHLTGLVDEVVPHDELIG
MAB_2058|M.abscessus_ATCC_1997 RGSPWATPLSWLVPPRVAMQILLTGDPITAARAHQVGLVNEVVPADQLRE
MMAR_4396|M.marinum_M PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLT
MUL_0210|M.ulcerans_Agy99 PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLT
Mb1099c|M.bovis_AF2122/97 PGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLT
Rv1070c|M.tuberculosis_H37Rv PGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLT
MLBr_02402|M.leprae_Br4923 PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLP
MAV_1195|M.avium_104 PGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLT
Mflv_2036|M.gilvum_PYR-GCK PGMGGSQRLTRAIGKAKAMDLILTGRNMDAEEAERAGLVSRVVPADSLLS
TH_4102|M.thermoresistible__bu PGMGGSQRLTRAIGKAKAMDLILTGRTIDAEEAERSGLVSRVVPADKLLD
Mvan_1871|M.vanbaalenii_PYR-1 PGGGMTAYLPQVVGAAMARRLSMTGEVVDAARAERIGLVTEVVVHDRLLD
* * : * : ::* : * . . *** .** * *
MSMEG_4020|M.smegmatis_MC2_155 VAGKLAAHIADLSPLALAHMKRTAHSARNQPVSVGLGLELTTFGDYIGSR
MAB_2058|M.abscessus_ATCC_1997 RTQQLALSIAANAPLSVLASKRTVYLSAQHHLAAAYDLADEIWEPVYLSD
MMAR_4396|M.marinum_M EAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATA
MUL_0210|M.ulcerans_Agy99 EAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATA
Mb1099c|M.bovis_AF2122/97 EARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATE
Rv1070c|M.tuberculosis_H37Rv EARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATE
MLBr_02402|M.leprae_Br4923 EAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTD
MAV_1195|M.avium_104 EAKKVATTISQMSRSAARMAKEAVNRAFETTLAEGLLYERRLFHSTFATA
Mflv_2036|M.gilvum_PYR-GCK EAKAVAQTIAGMSLSASRMAKEAVDRAFETTLSEGLLYERRLFHSAFATD
TH_4102|M.thermoresistible__bu EAKETAATIAAMSLSAARMAKEAVNRAFETSLAEGLLFERRVFHSAFATA
Mvan_1871|M.vanbaalenii_PYR-1 RAVELATQIAEVPRPTMRSLKEIYTTGAAAVTDPALAAEEEIAFAQHRDL
: * *: . : *. .
MSMEG_4020|M.smegmatis_MC2_155 D-FAEGMSAFSEHRAPVFTGQ
MAB_2058|M.abscessus_ATCC_1997 D-AQEGPAAFREKRAPQWKGH
MMAR_4396|M.marinum_M D-QSEGMAAFIEKRPPNFTHR
MUL_0210|M.ulcerans_Agy99 D-QSEGMAAFIEKRPPNFTHR
Mb1099c|M.bovis_AF2122/97 D-QSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv D-QSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 D-QSEGMAAFIEKRAPQFTHR
MAV_1195|M.avium_104 D-QSEGMAAFVEKRAPNFTHR
Mflv_2036|M.gilvum_PYR-GCK D-QTEGMNAFSEKRSPNFTHR
TH_4102|M.thermoresistible__bu D-QSEGMAAFTEKRPPKFTHR
Mvan_1871|M.vanbaalenii_PYR-1 DGLGDRFSAVAQRNKEQIRPS
* : *. ::.