For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTPALTSPWQPIGPALELGEGARLVDGQLLHVDLLKGRLFSRDVCTGDVHRLAALDIPLGAVAPVDGRAG EFIATLGTGIGFLAKGSVMREGPSFGVDATRVRVNDGACDPGGRFWAGVMAYEPSPEAGALFRIDRDGTI TRVVDGLAVPNGPAFSASGTVMYLADSAAGQIYRFDVDEAGHLTGREVFATVDGSPDGMTVDAESHLWTA IWGAGEVHRYAPTGDLVEVIPVPAQQPTSVAIGEGKVFVTSATHGLNQPGPDDGRTFAADCAVEGLPTSA FKPVTGGSSHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4005 | - | - | 100% (291) | calcium-binding protein |
| M. smegmatis MC2 155 | MSMEG_6378 | - | 2e-25 | 36.81% (182) | senescence marker protein-30 |
| M. smegmatis MC2 155 | MSMEG_2561 | - | 9e-14 | 35.20% (125) | gluconolactonase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4759 | - | 4e-28 | 33.20% (259) | SMP-30/gluconolaconase/LRE domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3680 | - | 1e-09 | 24.40% (168) | strictosidine synthase family protein |
| M. marinum M | MMAR_0391 | - | 9e-13 | 25.60% (250) | hypothetical protein MMAR_0391 |
| M. avium 104 | MAV_5132 | - | 9e-16 | 30.30% (165) | senescence marker protein-30 (SMP-30) |
| M. thermoresistible (build 8) | TH_0278 | - | 3e-14 | 26.09% (253) | gluconolactonase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2237 | - | 2e-14 | 34.45% (119) | SMP-30/gluconolaconase/LRE domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0391|M.marinum_M ------------MHDTFAVICNGTRREVSPLARGFCFGEGPRW--FEGLL
MAV_5132|M.avium_104 ------------------MIP-------EPLVNGFCFGEGPRW--FEGLL
TH_0278|M.thermoresistible__bu ------------------VLN------PTPLAKGFCFGEGPRW--FEGLL
Mvan_2237|M.vanbaalenii_PYR-1 -------------------MT------LTSLANGFCFGEGPRW--FEGLV
MSMEG_4005|M.smegmatis_MC2_155 -------------------MTPALTSPWQPIGPALELGEGARL--VDGQL
Mflv_4759|M.gilvum_PYR-GCK -------------------MTR---CAERLTPRAAHHGEGPFWDRRSGRL
MAB_3680|M.abscessus_ATCC_1997 MAKPSIDPVRWQPPGVRALSLEPQPLPRLSIVALPGHGPEDVVADAAGNI
* * :
MMAR_0391|M.marinum_M WFSDMLGEAVHTS---DMHGSLTTLPLPGHSPCGLGFRPDG--TLLIASA
MAV_5132|M.avium_104 WFSDMLGEAVHTT---TMGGALTTLPLPGHCPSGLGFRPDG--SLLIAST
TH_0278|M.thermoresistible__bu WFSDMLGEAVHTV---DLNGSMTTLPLPGHAPSGLGFRPDG--SLLIAST
Mvan_2237|M.vanbaalenii_PYR-1 WFSDMLGEAVHTV---TLAGEMSTLQLAGHAPSGLGFRPDG--SLLIVST
MSMEG_4005|M.smegmatis_MC2_155 LHVDLLKGRLFSR---DVCTGDVHRLAALDIPLGAVAPVDGRAGEFIATL
Mflv_4759|M.gilvum_PYR-GCK LFMDVLAGVVGAI---ESTGKVLRYDVPADVATVIRRRASG---GFVIAT
MAB_3680|M.abscessus_ATCC_1997 WAGVADGRIFRISPDDTEGAAVTHVATTEHPPLGLHIARDG--RVLICSR
. . . . .* :: :
MMAR_0391|M.marinum_M HDRLVLRYDGDTVVTVADLRDLAP-ADLGDMVIDRAGRAYIGCQSFS---
MAV_5132|M.avium_104 RDRRVLRYDGETVVTVAELADIAP-ADLGDMVVDRAGRAYIGCQAFT---
TH_0278|M.thermoresistible__bu EARCVLRYDGETVTTIADLSAFAP-DNLGDMVVDDAGRAYVGSQAYS---
Mvan_2237|M.vanbaalenii_PYR-1 ERRQILGYDGDSVTTVADLSAMVP-AALGDMVIDRHGGAYVGSQARE---
MSMEG_4005|M.smegmatis_MC2_155 GTGIGFLAKGSVMREGPSFGVDATRVRVNDGACDPGGRFWAGVMAYEP--
Mflv_4759|M.gilvum_PYR-GCK GHDLMCADDDLANFTHLTHVASDPHVRTNDGGCDPTGGFVIGTMAYDE--
MAB_3680|M.abscessus_ATCC_1997 DKLLALDPASGKIEPVVTKVDGPPLIFCSNVTESMDGTIYFSESTARFPF
. . .: . * . :
MMAR_0391|M.marinum_M ------------GGVIIRLDTDNS---AQVVAEDLDFPNGMVITPDHDTL
MAV_5132|M.avium_104 ------------RGAIIRLDPDDR---AKVVADDLDFPNGMAITPDGATL
TH_0278|M.thermoresistible__bu ------------GGVIVRVDPDDPDDPVTVVAEDLDFPNGMVITEDRSTL
Mvan_2237|M.vanbaalenii_PYR-1 ------------GGVIVRVDPDGR--TCEVVAEDLQFPNGMAITADGATL
MSMEG_4005|M.smegmatis_MC2_155 ---------SPEAGALFRIDRDGT---ITRVVDGLAVPNGPAFSASGTVM
Mflv_4759|M.gilvum_PYR-GCK ---------RTGGGAVYRVAPDCH---ATTLLAPVSISNGIQWSADGTRV
MAB_3680|M.abscessus_ATCC_1997 EQFMAAILEGRPTGRVFRRDPDGT---VTTIATGLAFTNGVTITADGSAL
* : * * : : ..** : . :
MMAR_0391|M.marinum_M IVAESVGRRLSAFTVSAD-GALNDRRVFAAG--LDGPPDGIALDAEGAVW
MAV_5132|M.avium_104 IVAESTGRRLSAFAIDDD-GALSGRRVFADG--LDGPPDGIALDADGGVW
TH_0278|M.thermoresistible__bu IVAESIGRRLTSYRIAAD-GTLTDREVFADG--LDGPPDGIALDAAGAVW
Mvan_2237|M.vanbaalenii_PYR-1 IVAESTGRRLTAFTIAED-GSLSGRRVFADG--LDGPPDGICLDAAGGVW
MSMEG_4005|M.smegmatis_MC2_155 YLADSAAGQIYRFDVDEA-GHLTGREVFAT---VDGSPDGMTVDAESHLW
Mflv_4759|M.gilvum_PYR-GCK FYIDTPTRRIDVFDVDLDTGRWSNRRVHIDMNNSIGYPDGMAIDVDQGLW
MAB_3680|M.abscessus_ATCC_1997 IIAETVGRRVSRYALTGP----AAGTLTPIVEEIPGMPDNISTGADGRIW
:: :: : : : * **.: .. :*
MMAR_0391|M.marinum_M AAMTLAH--QFERIVAGG--------VVTDRIDMG-DRVAIACALGGPGR
MAV_5132|M.avium_104 AAMTLAH--QFERIVAGG--------AVTDRIDIG-DRVAIACALGGPQR
TH_0278|M.thermoresistible__bu TSMTLAH--RFDRILPGG--------EVTDRIDIG-GRAAIACALGGPGR
Mvan_2237|M.vanbaalenii_PYR-1 VAMTLAH--QFERIEEGG--------EVTDRIDIG-ARTAIACTLGGPED
MSMEG_4005|M.smegmatis_MC2_155 TAIWGAG--EVHRYAPTG--------DLVEVIPVP-AQQPTSVAIG---E
Mflv_4759|M.gilvum_PYR-GCK VAMWGGG--AVNHYDAFG--------QLVETIEVPGVTQVSSCAFGGGSL
MAB_3680|M.abscessus_ATCC_1997 ITLASPRNALAEWLLPRSPAIRKVLWRLPDALLPGTDTDPWVIAVNPDTG
:: . . : : : :..
MMAR_0391|M.marinum_M RTLFLLSSTDAYPKR-----LIGTRLSQLDAVTVATPGAGLP--------
MAV_5132|M.avium_104 RTLFLLSSTDAYPQR-----LVGTRLSRLDAVTVTTPGAGLP--------
TH_0278|M.thermoresistible__bu NLLFLLSTTDAYPKR-----LIGTQSARLDVVKVDVAGAGLP--------
Mvan_2237|M.vanbaalenii_PYR-1 RTLFMLTAADAYPER-----LRGTTLSRLDATTVDIPAASPA--------
MSMEG_4005|M.smegmatis_MC2_155 GKVFVTSATHGLNQPG----PDDGRTFAADCAVEGLPTSAFKPVTGGSSH
Mflv_4759|M.gilvum_PYR-GCK DELFITTSRQGLPNDSE---PSAGAIFSTKTTTRGAALLEFAG-------
MAB_3680|M.abscessus_ATCC_1997 DVLANITGKSRDLRTVTGVVESGGRLWMGCIGSSAVGHISLADIASSSSG
: : .
MMAR_0391|M.marinum_M -
MAV_5132|M.avium_104 -
TH_0278|M.thermoresistible__bu -
Mvan_2237|M.vanbaalenii_PYR-1 -
MSMEG_4005|M.smegmatis_MC2_155 G
Mflv_4759|M.gilvum_PYR-GCK -
MAB_3680|M.abscessus_ATCC_1997 P