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TLTSLANGFCFGEGPRWFEGLVWFSDMLGEAVHTVTLAGEMSTLQLAGHAPSGLGFRPDGSLLIVSTERR QILGYDGDSVTTVADLSAMVPAALGDMVIDRHGGAYVGSQAREGGVIVRVDPDGRTCEVVAEDLQFPNGM AITADGATLIVAESTGRRLTAFTIAEDGSLSGRRVFADGLDGPPDGICLDAAGGVWVAMTLAHQFERIEE GGEVTDRIDIGARTAIACTLGGPEDRTLFMLTAADAYPERLRGTTLSRLDATTVDIPAASPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2237 | - | - | 100% (273) | SMP-30/gluconolaconase/LRE domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1568 | - | 3e-11 | 28.71% (202) | strictosidine synthase |
| M. vanbaalenii PYR-1 | Mvan_4964 | - | 2e-07 | 27.72% (202) | SMP-30/gluconolaconase/LRE domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4109 | - | 1e-127 | 80.95% (273) | SMP-30/gluconolaconase/LRE domain-containing protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3680 | - | 6e-12 | 29.17% (168) | strictosidine synthase family protein |
| M. marinum M | MMAR_0391 | - | 1e-103 | 68.28% (268) | hypothetical protein MMAR_0391 |
| M. avium 104 | MAV_5132 | - | 1e-111 | 73.21% (265) | senescence marker protein-30 (SMP-30) |
| M. smegmatis MC2 155 | MSMEG_2561 | - | 1e-107 | 69.85% (272) | gluconolactonase |
| M. thermoresistible (build 8) | TH_0278 | - | 1e-106 | 71.00% (269) | gluconolactonase |
| M. ulcerans Agy99 | MUL_4817 | - | 1e-05 | 28.03% (132) | hypothetical protein MUL_4817 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2237|M.vanbaalenii_PYR-1 -------------MT-------LTSLANGFCFG---EGPRWF--------
Mflv_4109|M.gilvum_PYR-GCK -------------MT-------LTPLADGFCFG---EGPRWF--------
MSMEG_2561|M.smegmatis_MC2_155 -------------MTTEAGPERTTELATGFCFG---EGPRWF--------
MMAR_0391|M.marinum_M -------MHDTFAVICNGTRREVSPLARGFCFG---EGPRWF--------
MAV_5132|M.avium_104 -------------MIP-------EPLVNGFCFG---EGPRWF--------
TH_0278|M.thermoresistible__bu -------------VLN------PTPLAKGFCFG---EGPRWF--------
MUL_4817|M.ulcerans_Agy99 MVRAVIPVTRRLQHAGHYPVTRAPNVAEGWTLTRLTAPSRLFGANGLRTG
MAB_3680|M.abscessus_ATCC_1997 MAKPSIDPVRWQPPGVRALSLEPQPLPRLSIVALPGHGPEDVVAD-----
: . .. .
Mvan_2237|M.vanbaalenii_PYR-1 -EGLVWFSDMLGEAVHTVTLA-GEMSTLQLAG---HAPSGLGFRPDGSLL
Mflv_4109|M.gilvum_PYR-GCK -EGLVWFSDMLGEAVHTVTLD-GATSTLALPG---HAPSGLGFRPDGTLL
MSMEG_2561|M.smegmatis_MC2_155 -EGLLWFSDMLGEAVHTVTLG-GSMTTLPLPG---HAPSGLGFRPDGTLY
MMAR_0391|M.marinum_M -EGLLWFSDMLGEAVHTSDMH-GSLTTLPLPG---HSPCGLGFRPDGTLL
MAV_5132|M.avium_104 -EGLLWFSDMLGEAVHTTTMG-GALTTLPLPG---HCPSGLGFRPDGSLL
TH_0278|M.thermoresistible__bu -EGLLWFSDMLGEAVHTVDLN-GSMTTLPLPG---HAPSGLGFRPDGSLL
MUL_4817|M.ulcerans_Agy99 PDGRVYIAQVTGSQISALDLSTGRLDTVCPKGGAIIAPDDLAFDQDGNLY
MAB_3680|M.abscessus_ATCC_1997 AAGNIWAGVADGRIFRISPDD-TEGAAVTHVATTEHPPLGLHIARDGRVL
* :: . * . :: . * .* : ** :
Mvan_2237|M.vanbaalenii_PYR-1 IVSTER--RQILGYDGDSVTTVADLSAMVPAALGD--------------M
Mflv_4109|M.gilvum_PYR-GCK IVSTEL--RQVLGYDGETVVTVADLSALVPANLGD--------------M
MSMEG_2561|M.smegmatis_MC2_155 IVSTEK--RQVLCYDGETVELLADLHQVAPAPLGD--------------M
MMAR_0391|M.marinum_M IASAHD--RLVLRYDGDTVVTVADLRDLAPADLGD--------------M
MAV_5132|M.avium_104 IASTRD--RRVLRYDGETVVTVAELADIAPADLGD--------------M
TH_0278|M.thermoresistible__bu IASTEA--RCVLRYDGETVTTIADLSAFAPDNLGD--------------M
MUL_4817|M.ulcerans_Agy99 ATEVMDGRVSVRAPDGHTRVLRDDIPSANGITFHQGRLFVGECRDGGRLL
MAB_3680|M.abscessus_ATCC_1997 ICSRDK--LLALDPASGKIEPVVTKVDGPPLIFCSN-------------V
. . . : . :
Mvan_2237|M.vanbaalenii_PYR-1 VIDRHG--------------------------------------------
Mflv_4109|M.gilvum_PYR-GCK TVDRHG--------------------------------------------
MSMEG_2561|M.smegmatis_MC2_155 VLDERG--------------------------------------------
MMAR_0391|M.marinum_M VIDRAG--------------------------------------------
MAV_5132|M.avium_104 VVDRAG--------------------------------------------
TH_0278|M.thermoresistible__bu VVDDAG--------------------------------------------
MUL_4817|M.ulcerans_Agy99 ELDLNGGAPRVLARNLPSPNAMEVGPDGLLYFPVMGANEIWRIDPDGGVP
MAB_3680|M.abscessus_ATCC_1997 TESMDG--------------------------------------------
. *
Mvan_2237|M.vanbaalenii_PYR-1 -----------------GAYVGSQAREGGVIVRVDPDG------------
Mflv_4109|M.gilvum_PYR-GCK -----------------CAYVGSQARDGGVIVRVDPDT------------
MSMEG_2561|M.smegmatis_MC2_155 -----------------RAYVGSQARGGGVIVRIDPDDPV----------
MMAR_0391|M.marinum_M -----------------RAYIGCQSFSGGVIIRLDTDNS-----------
MAV_5132|M.avium_104 -----------------RAYIGCQAFTRGAIIRLDPDDR-----------
TH_0278|M.thermoresistible__bu -----------------RAYVGSQAYSGGVIVRVDPDDPD----------
MUL_4817|M.ulcerans_Agy99 QCVAGDLRVPDAVKFDPHGHLVSTQVHSGEVLRINPRTGDRTVLAALHPG
MAB_3680|M.abscessus_ATCC_1997 --TIYFSESTARFPFEQFMAAILEGRPTGRVFRRDPDG------------
* :.* :.
Mvan_2237|M.vanbaalenii_PYR-1 ---------------------------RTCEVVAEDLQFPNGMAITADGA
Mflv_4109|M.gilvum_PYR-GCK ---------------------------GRATVVAENLQFPNGMALTADGA
MSMEG_2561|M.smegmatis_MC2_155 ---------------------------EPIRVVAEGLDFPNGMAITPDGE
MMAR_0391|M.marinum_M -----------------------------AQVVAEDLDFPNGMVITPDHD
MAV_5132|M.avium_104 -----------------------------AKVVADDLDFPNGMAITPDGA
TH_0278|M.thermoresistible__bu ---------------------------DPVTVVAEDLDFPNGMVITEDRS
MUL_4817|M.ulcerans_Agy99 LDNLTFVGERLFVSSFTGEITEILGTGETRTTLPGGLTWPLGLAVAADGD
MAB_3680|M.abscessus_ATCC_1997 ----------------------------TVTTIATGLAFTNGVTITADGS
.:. .* :. *:.:: *
Mvan_2237|M.vanbaalenii_PYR-1 TLIVAES-----------------------------TGRRLTAFTIAEDG
Mflv_4109|M.gilvum_PYR-GCK TLIVAES-----------------------------TGRRLTAYSVADDG
MSMEG_2561|M.smegmatis_MC2_155 TLIVAES-----------------------------TARRLTAYTVDEDG
MMAR_0391|M.marinum_M TLIVAES-----------------------------VGRRLSAFTVSADG
MAV_5132|M.avium_104 TLIVAES-----------------------------TGRRLSAFAIDDDG
TH_0278|M.thermoresistible__bu TLIVAES-----------------------------IGRRLTSYRIAADG
MUL_4817|M.ulcerans_Agy99 LYIADGTYFYVLLADGTLRVGGMLFSAGYPGFLRGVAALGSGEFAVTTSN
MAB_3680|M.abscessus_ATCC_1997 ALIIAET-----------------------------VGRRVSRYALTGPA
* : . : :
Mvan_2237|M.vanbaalenii_PYR-1 S--------LSGRRVFADGLD-----------------------------
Mflv_4109|M.gilvum_PYR-GCK T--------LSDRRIFADGLD-----------------------------
MSMEG_2561|M.smegmatis_MC2_155 D--------LSDRRIFAEGLD-----------------------------
MMAR_0391|M.marinum_M A--------LNDRRVFAAGLD-----------------------------
MAV_5132|M.avium_104 A--------LSGRRVFADGLD-----------------------------
TH_0278|M.thermoresistible__bu T--------LTDREVFADGLD-----------------------------
MUL_4817|M.ulcerans_Agy99 GEVARYRPWASETEVLATGLDQLYGVAVAGSGALFVAERGAGRVLSVRPD
MAB_3680|M.abscessus_ATCC_1997 AG-------TLTPIVEEIP-------------------------------
:
Mvan_2237|M.vanbaalenii_PYR-1 ---------GPPDGICLDAAGGVWVAMTLAH--QFERIEEGG--------
Mflv_4109|M.gilvum_PYR-GCK ---------GPPDGICLDDEGGVWVGMTLAH--QFERVVETGG-QA----
MSMEG_2561|M.smegmatis_MC2_155 ---------GPPDGIAIDLEGGVWTALTLAH--EFQRIVDSGPGTP----
MMAR_0391|M.marinum_M ---------GPPDGIALDAEGAVWAAMTLAH--QFERIVAGG--------
MAV_5132|M.avium_104 ---------GPPDGIALDADGGVWAAMTLAH--QFERIVAGG--------
TH_0278|M.thermoresistible__bu ---------GPPDGIALDAAGAVWTSMTLAH--RFDRILPGG--------
MUL_4817|M.ulcerans_Agy99 GVEVMASGLSDPVGVAVTADGRCVVTEADAG--RVRTLGDTGTLLDGLQC
MAB_3680|M.abscessus_ATCC_1997 ---------GMPDNISTGADGRIWITLASPRNALAEWLLPRSPAIR----
. * .:. * : . : .
Mvan_2237|M.vanbaalenii_PYR-1 ----EVTDR----IDIGARTAIACTLGGPEDR----TLFMLTAADAYPER
Mflv_4109|M.gilvum_PYR-GCK ----RVTDR----IDMGGRTAIACTLGGPEGR----TLFLVTTTDAYPER
MSMEG_2561|M.smegmatis_MC2_155 ----TVTDR----IDAGGRTAIACALGGAEGR----TLFLVTTTDAYPQR
MMAR_0391|M.marinum_M ----VVTDR----IDMGDRVAIACALGGPGRR----TLFLLSSTDAYPKR
MAV_5132|M.avium_104 ----AVTDR----IDIGDRVAIACALGGPQRR----TLFLLSSTDAYPQR
TH_0278|M.thermoresistible__bu ----EVTDR----IDIGGRAAIACALGGPGRN----LLFLLSTTDAYPKR
MUL_4817|M.ulcerans_Agy99 PQGVAICDRQVYVIDSGAKQLVAVDLGSRTRHTIAWDLPVGAPAGVTPNP
MAB_3680|M.abscessus_ATCC_1997 ----KVLWRLPDALLPGTDTDPWVIAVNPDTG---DVLANITGKSRDLRT
: * : * . * : . .
Mvan_2237|M.vanbaalenii_PYR-1 LRGTTLS--RLDATTVDIPAAS--PA------------------
Mflv_4109|M.gilvum_PYR-GCK LRGTTLS--RLDAVTVDVPAAG--FVGEVHVH------------
MSMEG_2561|M.smegmatis_MC2_155 LVGTKLS--RIEALDVAVPAPGDFAVGDHHHH------------
MMAR_0391|M.marinum_M LIGTRLS--QLDAVTVATPGAG--LP------------------
MAV_5132|M.avium_104 LVGTRLS--RLDAVTVTTPGAG--LP------------------
TH_0278|M.thermoresistible__bu LIGTQSA--RLDVVKVDVAGAG--LP------------------
MUL_4817|M.ulcerans_Agy99 LRGMPPF--SGPEGPFAAITPGPDATLYISADADGSVLALRRES
MAB_3680|M.abscessus_ATCC_1997 VTGVVESGGRLWMGCIGSSAVGHISLADIASSSSGP--------
: * . .