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MNSRSAIELADVDAIGQAELLAAGDLTAAELLEAAIVRVEATRHLNAVITDLFERGRAQAGALDASGVLR KGEAGPLAGVPFLLKDLGAALAGAPEAMGSVALRDHVATDSAWTVQRYLDAGLVVFGKTNTPEWGNHCTT EPVLFGPTVNPWGSDVTPGGSSGGSAAAVAAGVVPAASGGDGTGSIRVPASCCGLVGLKPRRGRSSFAPD GGHGLEGLVNSHALTRTVRDCAALLDVIAGSVSGDPYAAPAAETPFLQSLTPPPPLRVLMSTGSPFPNDG VDPQVVAAVEATGRILESLGHHVTPGPGPVIDPDAVADAIAVLHNVSNAQLHAFAASHLGREPREDEFEP STWVMIREGFTTTGVAYAEAISTVHAQTRRFAAGMSGHDVLLVPTLLTTTPPYALLNQPRGTTRAFFDVE FATTGWTSLANVTGWAAISLPLGVSGDGLPVGVQLMAPDEAVLLGLAAAIEEAAPWADRKPAGWVRTDGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3505 | - | - | 100% (490) | 6-aminohexanoate-cyclic-dimer hydrolase |
| M. smegmatis MC2 155 | MSMEG_6673 | - | 2e-89 | 42.05% (497) | 6-aminohexanoate-cyclic-dimer hydrolase |
| M. smegmatis MC2 155 | MSMEG_4492 | - | 1e-53 | 34.67% (499) | amidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2384 | amiA2 | 5e-59 | 37.05% (475) | amidase |
| M. gilvum PYR-GCK | Mflv_1016 | - | 5e-88 | 42.46% (504) | amidase |
| M. tuberculosis H37Rv | Rv2363 | amiA2 | 5e-59 | 37.05% (475) | amidase |
| M. leprae Br4923 | MLBr_01596 | - | 7e-55 | 35.16% (475) | amidase |
| M. abscessus ATCC 19977 | MAB_2181c | - | 6e-80 | 39.76% (498) | putative amidase |
| M. marinum M | MMAR_3565 | amiC_1 | 4e-81 | 42.18% (486) | amidase AmiC_1 |
| M. avium 104 | MAV_0676 | - | 2e-81 | 41.25% (497) | 6-aminohexanoate-cyclic-dimer hydrolase |
| M. thermoresistible (build 8) | TH_4482 | - | 2e-59 | 36.84% (475) | PUTATIVE Amidase |
| M. ulcerans Agy99 | MUL_2798 | amiC_1 | 9e-80 | 41.77% (486) | amidase AmiC_1 |
| M. vanbaalenii PYR-1 | Mvan_5822 | - | 1e-84 | 41.01% (495) | amidase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3565|M.marinum_M ----------MSTLAEQTRWMDATDQAALVAAGEASPSELLEAAIERIER
MUL_2798|M.ulcerans_Agy99 ----------MSTLAEQTRWMDATDQAALVVAGEASPSELLEAAIERIER
Mflv_1016|M.gilvum_PYR-GCK ------------MDFLEYRSHDATGLAKLVADGDVTADELLTLARERAAA
Mvan_5822|M.vanbaalenii_PYR-1 -----------MVDFQEYRAQDATGLARLVAEKQVTADELLALAQARAAQ
MAB_2181c|M.abscessus_ATCC_199 ------------MDFSDYSQHDATGLAELVATKQVTPAELLAAARARAAD
MAV_0676|M.avium_104 ------------------MALDATALAGLVADKQVTPAELLALARQRADA
MLBr_01596|M.leprae_Br4923 ------MQRVHAFGDDALGDLDAVGLADAIRAGWVSRADVIEAAIVRTEA
MSMEG_3505|M.smegmatis_MC2_155 ---------MNSRSAIELADVDAIGQAELLAAGDLTAAELLEAAIVRVEA
Mb2384|M.bovis_AF2122/97 MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSLRAIDV
Rv2363|M.tuberculosis_H37Rv MVGASGSDAGAISGSGNQRLPTLTDLLYQLATRAVTSEELVRRSLRAIDV
TH_4482|M.thermoresistible__bu MVDAYKPPA---------KLPTLTDLLYQLASGAVTSQELVRRSLRAIEA
: : ::: :
MMAR_3565|M.marinum_M INPALNAVVIRWFDHARETASADLPG--------GPFRGVPFLIKDLYAL
MUL_2798|M.ulcerans_Agy99 INPALNAVVIRWFDHARETASADLPG--------GPFRGVPFLIKDLYAL
Mflv_1016|M.gilvum_PYR-GCK VNPKINAIVRDVPAP-----VGGNRG--------GPFAGVPFLIKDLAQD
Mvan_5822|M.vanbaalenii_PYR-1 VNPRINAIVRDVPAA-----PAGIAD--------GPFAGVPFLIKDLAQD
MAB_2181c|M.abscessus_ATCC_199 VNNKIGAIVRTLPEADQ--QVQGDLT--------GPFAGVPFLIKDLGQD
MAV_0676|M.avium_104 VNPRLNAIVCRLDDVADRQAADPNLS--------GPFAGVPFLLKDLGQE
MLBr_01596|M.leprae_Br4923 VNPALGGLAYEAFQWAR-QTASKAGS--------GFFSGVPTFIKDN-ID
MSMEG_3505|M.smegmatis_MC2_155 TR-HLNAVITDLFERGRAQAGALDASGVLRKGEAGPLAGVPFLLKDLGAA
Mb2384|M.bovis_AF2122/97 SQPTLNAFRVVLTESALADAAAADKRRAAG--DTAPLLGIPIAVKDD-VD
Rv2363|M.tuberculosis_H37Rv SQPTLNAFRVVLTESALADAAAADKRRAAG--DTAPLLGIPIAVKDD-VD
TH_4482|M.thermoresistible__bu SQSTLNAFRVVLADRALAEAAEADRKRAAG--EHLPLLGVPIAVKDD-VD
. :... : *:* :**
MMAR_3565|M.marinum_M YAGQPISNGNLAFKQAHVIADADTTLVGRYRAAGLVIAGRTNSPELGSLP
MUL_2798|M.ulcerans_Agy99 YAGQPISNGNLAFKQAHVIADADTTLVGRYRAAGLVIAGRTNSPELGSLP
Mflv_1016|M.gilvum_PYR-GCK YAGLPTASGSRSLMS--RPAGEHATVVQRWLDAGLVIFGKTNTPEFGAKG
Mvan_5822|M.vanbaalenii_PYR-1 YAGLPSSRGSRALMS--LPAAEHSTIVQRWIDAGVVIFGKTNTPEFGAKG
MAB_2181c|M.abscessus_ATCC_199 YKGHPTSGGCRALST--LPAPEHSTIVRRWLDAGLVIFGKTNTPEFGSKG
MAV_0676|M.avium_104 YRGFPTSCGSRSLAN--DVADRHALVTQRFLDAGLVIFGKTNTPEFGAKG
MLBr_01596|M.leprae_Br4923 VAGQPTMRGSDAWVP--RNAFDDGEFTRLYLATGPVSLGKTQLSEFGFSA
MSMEG_3505|M.smegmatis_MC2_155 LAGAPEAMGSVALRD--HVATDSAWTVQRYLDAGLVVFGKTNTPEWGNHC
Mb2384|M.bovis_AF2122/97 VAGVPTAFGTQGYVA---PATDDCEVVRRLKAAGAVIVGKTNTCELGQWP
Rv2363|M.tuberculosis_H37Rv VAGVPTAFGTQGYVA---PATDDCEVVRRLKAAGAVIVGKTNTCELGQWP
TH_4482|M.thermoresistible__bu IAGVPTRFGAVGDVP---PATEDAEVVRRLRAAGAVIVGKTHTCELGQWP
* * * . * . :* * *:*: * *
MMAR_3565|M.marinum_M TTEPVAWGPTRNPWDTSRTPGGSSGGSAAAVASGMVPFAHASDGGGSIRI
MUL_2798|M.ulcerans_Agy99 TTEPVAWGPTRNPWDTSRTPGGSSGGSAAAVASGMVPFAHASDGGGSIRI
Mflv_1016|M.gilvum_PYR-GCK ITEPQAYGPARNPWDLTRSPGGSSGGSAAAVAAGITPCAGASDGGGSIRI
Mvan_5822|M.vanbaalenii_PYR-1 ITEPVAWGPTRNPWDVTRTPGGSSGGSAAAVAAGIVPCAGANDGGGSIRI
MAB_2181c|M.abscessus_ATCC_199 ITEPELFGASRNPWDLGRTPGGSSGGSAAAVAAGIVPVAGASDGGGSIRI
MAV_0676|M.avium_104 VTEPDYWGPARNPWDTERTPGGSSGGSGAAVAAGIVPAAGANDGGGSIRI
MLBr_01596|M.leprae_Br4923 SAEHMRLGPVRNPWDTDYTAGASSSGSGAFVAAGVVPMAHANDGGGSIRI
MSMEG_3505|M.smegmatis_MC2_155 TTEPVLFGPTVNPWGSDVTPGGSSGGSAAAVAAGVVPAASGGDGTGSIRV
Mb2384|M.bovis_AF2122/97 FTSGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRI
Rv2363|M.tuberculosis_H37Rv FTSGPGFGHTRNPWSRRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSIRI
TH_4482|M.thermoresistible__bu FTSGPAFGHTRNPWSPRHTPGGSSGGSAAAVAAGLVTAAIGSDGAGSVRI
:. * ***. :.*.**.**.* **:*:.. * ..** **:*:
MMAR_3565|M.marinum_M PASCCGLVGLKPSQGRITLGPLREE--SGMSVEHCLSRTVRDTAALLDAT
MUL_2798|M.ulcerans_Agy99 PASCCGLVGLKPSQGRITLGPLREE--SGMSVEHCLSRTVRDTAALLDAT
Mflv_1016|M.gilvum_PYR-GCK PAACCGLVGLKPGRGLTPSGPASGEAMHGAAVQGVVTRTVRDSAAMLDVI
Mvan_5822|M.vanbaalenii_PYR-1 PAACCGLVGLKPGRGLTPMGPELGESMHGSAVQGVVSRTVRDTAAMLDVI
MAB_2181c|M.abscessus_ATCC_199 PAGCCGLVGLKPGRGITPMGPTAGEPMHGAAVNGTVSRTVRDTASMLDII
MAV_0676|M.avium_104 PAACNGLVGLKPSRGLAPYGPQTGELMLGMATQGVVTRTVRDSAALLDAI
MLBr_01596|M.leprae_Br4923 PASCNGLVGLKPSRGRLPLDSELRRLPVGIVVNGVLTRSVRDTAAFYREA
MSMEG_3505|M.smegmatis_MC2_155 PASCCGLVGLKPRRGRSSFAPDGGHGLEGLVNSHALTRTVRDCAALLDVI
Mb2384|M.bovis_AF2122/97 PAAWTHLVGIKPQRGRISTWP-LPEAFNGVTVNGVLARTVEDAALVLDAA
Rv2363|M.tuberculosis_H37Rv PAAWTHLVGIKPQRGRISTWP-LPEAFNGVTVNGVLARTVEDAALVLDAA
TH_4482|M.thermoresistible__bu PAAWTHLVGIKPQRGRISTWP-LPEAFNGITVHGVLARTVTDAALVLDAA
**. ***:** :* . . . * ::*:* * * .
MMAR_3565|M.marinum_M RGPGVGDTVIAPPPIRPYTEELGADPGRLRIGILDHHPR-GGPVDAEVTH
MUL_2798|M.ulcerans_Agy99 RGPGVGDTVIAPPPIRPYTEELGADPGRLRIGILDHHPR-GGPVDAEVTH
Mflv_1016|M.gilvum_PYR-GCK SGGEPYGPFVPALPEASFASCVGTDPGTLRIGVRVPSAI-TPQPHREAFA
Mvan_5822|M.vanbaalenii_PYR-1 SGGEPWGPFTPGMPNAPFASCVGQDPGRLRIGVRVPTAI-TPVPHREAFA
MAB_2181c|M.abscessus_ATCC_199 AGPEPTSPYLSAMPQDSYASQVGRDPGRLRIGVRVPTVI-TPNPDPAAVA
MAV_0676|M.avium_104 IGHHPDASYRVALPDKPFAQQITRPPGPLTIGYSARSAL-NPRPDREAVA
MLBr_01596|M.leprae_Br4923 ER----IWHNPKLPPVGDVTQPGRQ--RLRIAVVTRSVQ-RECS-PELRE
MSMEG_3505|M.smegmatis_MC2_155 AGSVSGDPYAAPAAETPFLQSLTPPP-PLRVLMSTGSPFPNDGVDPQVVA
Mb2384|M.bovis_AF2122/97 SGNVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYTGFRAKLHPEILA
Rv2363|M.tuberculosis_H37Rv SGNVEGDRHQPPPVTVSDFVGIAPGPLKIALSTHFPYTGFRAKLHPEILA
TH_4482|M.thermoresistible__bu SGNAPGDLHQPPPVRVSDYVGQAPGPLRIAVSTKFPFTLFRAKLHPEIRA
: :
MMAR_3565|M.marinum_M ATQAVGRLLESLGHHVDVAWPAALEDASFDSTFGALWSTNMGLAQRRFEE
MUL_2798|M.ulcerans_Agy99 ATQAVCRLLESLGHHVEVAWPAALEDASFDSTFGALWSTNMGLAQRRFEE
Mflv_1016|M.gilvum_PYR-GCK AVEATTRLLTDLGHEVTELAEAPYDDAVLARDFLLTWFVTLAWEVAEAKR
Mvan_5822|M.vanbaalenii_PYR-1 AVEATVQTLTDLGHHVDELPQAPFDDAALAREFLLTWFVYTAWELADAKR
MAB_2181c|M.abscessus_ATCC_199 AVETAIRLLTHLGHEVEEVS-APYDDGQLARDFLLTWFVHAAYEVDYTKR
MAV_0676|M.avium_104 AVENSAALLSALGHRVREVA-PPYDDAALGRDFLTIWFAQLHQQVADIRR
MLBr_01596|M.leprae_Br4923 LTLKSARLLEELGHRVERVAEPPVPPN-FPDDFLLYWGLLAAMQVRTGRL
MSMEG_3505|M.smegmatis_MC2_155 AVEATGRILESLGHHVTPGPGPVIDPDAVADAIAVLHNVSNAQLHAFAAS
Mb2384|M.bovis_AF2122/97 ATQRVGDQLELLGHTVVKGN------PDYGLRLSWNFLARSTAGLWEWAE
Rv2363|M.tuberculosis_H37Rv ATQRVGDQLELLGHTVVKGN------PDYGLRLSWNFLARSTAGLWEWAE
TH_4482|M.thermoresistible__bu AVQTVADQLEQLGHTVFPAD------PEYTVGMSWSFLSRSTAGLLDWSR
. * *** * :
MMAR_3565|M.marinum_M QLGRPLGEDEFELVNRAQADFAKHFTSVD-YALALSAIAAFRRAIQSWWH
MUL_2798|M.ulcerans_Agy99 QLGRPLGEDEFELVNRAQADFAKHFTSVD-YALALSAIAAFRRAIQSWWH
Mflv_1016|M.gilvum_PYR-GCK LTG--AGDDQFETDTLVMAALGRATSSVD-YVDAVQRRHEHTRRLTRFFE
Mvan_5822|M.vanbaalenii_PYR-1 LTG--AGDDAFERDTLILAAIGRATSSVD-YLDAVQRRHDHTRRLTRFFD
MAB_2181c|M.abscessus_ATCC_199 LTG--AGDEGFERDTLLIAALGRTTSGPE-YVAAVERRHDYVRELATFFG
MAV_0676|M.avium_104 RTG--ARDNDFEADTLAISELGRSGGVLP-VMSALENRNTYIQSLAAFHE
MLBr_01596|M.leprae_Br4923 AFG--NTFDRTKLDSLTLGLDRHASRNMHRLPKAIMRLRRLRRRTADFFA
MSMEG_3505|M.smegmatis_MC2_155 HLGREPREDEFEPSTWVMIREGFTTTGVA-YAEAISTVHAQTRRFAAGMS
Mb2384|M.bovis_AF2122/97 RLG-----DEVTLDRRTVSNLRMGHVLSQAILRSARRHEAADQRRVGSIF
Rv2363|M.tuberculosis_H37Rv RLG-----DEVTLDRRTVSNLRMGHVLSQAILRSARRHEAADQRRVGSIF
TH_4482|M.thermoresistible__bu RLG-----DNVLWDKRTVANMRLGRLLSESALRKARAREAAAQRRMSWIF
* : :
MMAR_3565|M.marinum_M DGWDLLLTPTVASLPVKLGTIVSTPEHP---------------------M
MUL_2798|M.ulcerans_Agy99 DGWDLLLTPTVASLPVKLGTIVSTPEHP---------------------M
Mflv_1016|M.gilvum_PYR-GCK S-YDLLLTPTLATPPPRIGEFDMPAVMQRAADVLLKTRTARLLRHTGIVD
Mvan_5822|M.vanbaalenii_PYR-1 S-YDLLLTPSLATPPPAIGEFDLPVALQKASDVLLKTRTAHLLRFTKIVD
MAB_2181c|M.abscessus_ATCC_199 D-YDLLLTPTLAKAPPRIGEFNLPAPLAAVSDLLLRTKTARVLKYANIVD
MAV_0676|M.avium_104 G-YDFFLTPTLATPPLVVGATSTSAALQRAARLVSRVRGGKLMRLSGILD
MLBr_01596|M.leprae_Br4923 T-YDVLLTPTVADETPRIGYLTPTDYQQ----------------------
MSMEG_3505|M.smegmatis_MC2_155 G-HDVLLVPTLLTTTPPYALLNQPRGTTR---------------------
Mb2384|M.bovis_AF2122/97 DIVDVVLAPTTAQPPPMARAFDRLGSFG----------------------
Rv2363|M.tuberculosis_H37Rv DIVDVVLAPTTAQPPPMARAFDRLGSFG----------------------
TH_4482|M.thermoresistible__bu NIADVVLAPTTALPPPEVHAFDQLGGLA----------------------
*..*.*: .
MMAR_3565|M.marinum_M AAMQRAGEFVPFTPPFNTSGQPAISLPLEWTPEGLPLGVQLVAAYGREDV
MUL_2798|M.ulcerans_Agy99 AAMQRAGEFVPFTPPFNTSGQPAISLPLEWTPEGLPLGVQLVAAYGREDV
Mflv_1016|M.gilvum_PYR-GCK DMVDQNLGWVPYTQLANITGRPAISLPLHWTADGLPLGVQFVAPLAGEAL
Mvan_5822|M.vanbaalenii_PYR-1 DIVDKNLGWVPYTQLANITGRPAISLPLHWTEEGLPLGVQFVAPLGGESL
MAB_2181c|M.abscessus_ATCC_199 SMINDNLGWVPYTQLANLTGRPAISLPLYQTPKGLPLGVQFVAPLGGESL
MAV_0676|M.avium_104 DLIRESLGWVPYTQLANLTGRPAISVPLHWTDDGLPLGVQFVGKLGADGD
MLBr_01596|M.leprae_Br4923 -VMDRLMGWVAFTPLQNVTGEPAISLPLAQSADGMPVGMMFTADFGQEAQ
MSMEG_3505|M.smegmatis_MC2_155 AFFDVEFATTGWTSLANVTGWAAISLPLGVSGDGLPVGVQLMAP--DEAV
Mb2384|M.bovis_AF2122/97 -TDRAIIAACPSTWPWNLLGWPSINVPAGFTSDGLPIGVQLMGPANSEGM
Rv2363|M.tuberculosis_H37Rv -TDRAIIAACPSTWPWNLLGWPSINVPAGFTSDGLPIGVQLMGPANSEGM
TH_4482|M.thermoresistible__bu -TDRLMIKACPVTWPWNLLGWPSINVPAGFTSDGLPIGVQLMGPANSEPL
* * * .:*.:* : .*:*:*: : . :
MMAR_3565|M.marinum_M LLRIASQLEQAKPWAQRTPDI------------------
MUL_2798|M.ulcerans_Agy99 LLRIASQLEQAKPWAQRTPDI------------------
Mflv_1016|M.gilvum_PYR-GCK LLRLAGQLEQAAPWAHRTAAL------------------
Mvan_5822|M.vanbaalenii_PYR-1 LVRLAAQLEQAMPWRDRVAPV------------------
MAB_2181c|M.abscessus_ATCC_199 LIRLAAQLEATEPWAHRRPTL------------------
MAV_0676|M.avium_104 LLQLAAQLEQARPWAQRHPAPVTPPN-------------
MLBr_01596|M.leprae_Br4923 LLELAFELEEARPWARIQIGD------------------
MSMEG_3505|M.smegmatis_MC2_155 LLGLAAAIEEAAPWADRKPAGWVRTDGA-----------
Mb2384|M.bovis_AF2122/97 LISLAAELEAVSGWATKQPQVWWTS--------------
Rv2363|M.tuberculosis_H37Rv LISLAAELEAVSGWATKQPQVWWTS--------------
TH_4482|M.thermoresistible__bu LVSLAAALEGINGWAARQPRPWWLTPPAAPXXXASAAAS
*: :* :* *