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SFDRYETLAVTRDGAVLVIGLNRPDKRNAFNREMIGELAEVLGKLDSDDELRVGVLYGEGKGFTSGLDLP DVAPSLQDGSLQIPEGGINPWQVDGRRLTKPLVTAVHGKCLTLGIELLLASDIVVASESATFAQLEIARG IYPFGGATPRFPRVAGWGNAMRWMLTAEEFDSAEALRIGVVQEVVDDGAHIARAVQLAHVIAAQAPLGVQ ATLRSARLAQRDGEAAAEAELVPTIVKLFGTEDSRIGLESFATRRPAQFVGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3362 | - | - | 100% (263) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5915 | - | 4e-34 | 35.69% (255) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_2227 | - | 5e-31 | 34.24% (257) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 3e-36 | 35.41% (257) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1542 | - | 5e-35 | 36.25% (251) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3516 | echA19 | 4e-36 | 35.41% (257) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_00120 | echA1 | 3e-23 | 30.04% (273) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1493c | - | 5e-96 | 65.89% (258) | enoyl-CoA hydratase |
| M. marinum M | MMAR_0471 | - | 2e-75 | 55.68% (264) | enoyl-CoA hydratase |
| M. avium 104 | MAV_0643 | - | 3e-37 | 36.29% (259) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_1820 | echA19 | 8e-36 | 36.19% (257) | POSSIBLE ENOYL-CoA HYDRATASE ECHA19 (ENOYL HYDRASE) |
| M. ulcerans Agy99 | MUL_1121 | - | 3e-74 | 56.03% (257) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_5216 | - | 1e-35 | 34.65% (254) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_3362|M.smegmatis_MC2_155 ----------------------MSFDRYETLAVTRDGAVLVIGLNRPDKR
MAB_1493c|M.abscessus_ATCC_199 ------------------------MSDYETLRIRRDGYVLVIGLNRPAKR
MMAR_0471|M.marinum_M ---------------MQMTTTETSLPKLATVSLERDGHVLLIGLNRPQKR
MUL_1121|M.ulcerans_Agy99 ------------------------------MSLERDGHVLLIGLNRPQKR
Mb3545|M.bovis_AF2122/97 ------------------------MESGPDALVERRGHTLIVTMNRPAAR
Rv3516|M.tuberculosis_H37Rv ------------------------MESGPDALVERRGHTLIVTMNRPAAR
MAV_0643|M.avium_104 -----------------MAEASANEKTGPDALVEQRGHTLIVTLNRPHAR
Mflv_1542|M.gilvum_PYR-GCK MLHFQTSLWHRRWKADQFVSDEQNPEKAPDALVEQRGHTLIVTMNRPEKR
Mvan_5216|M.vanbaalenii_PYR-1 ------------------MSD---PQKGPDALVEQRGHTLIVTLNRPEAR
TH_1820|M.thermoresistible__bu -----------------VDQPVSALGSQPHALIEQRGHTLILTLNRPEAR
MLBr_00120|M.leprae_Br4923 -------------------MGSDINRAYESVAVEIKDRVAQVTLIGPGKG
: . . : : *
MSMEG_3362|M.smegmatis_MC2_155 NAFNREMIGELAEVLGKLDSDDELRVGVLYGEGKGFTSGLDLPDVA----
MAB_1493c|M.abscessus_ATCC_199 NAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASVA----
MMAR_0471|M.marinum_M NSFDRAMFADLSRAYALLETDDSVRAGVLFAHGDHFTGGLDLVDVA----
MUL_1121|M.ulcerans_Agy99 NSFDRAMFADLSRAYALLETDDSVRAGVLFAHGDHFTGGLDLVDVA----
Mb3545|M.bovis_AF2122/97 NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAAT----
Rv3516|M.tuberculosis_H37Rv NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAAT----
MAV_0643|M.avium_104 NALSTEMMEIMVQAWDRVDNDDDIRCCILTGAGGYFCAGMDLKAAT----
Mflv_1542|M.gilvum_PYR-GCK NALSAEMMQIMVEAWDRVDSDPEIRSCILTGAGGAFCAGMDLKKAD----
Mvan_5216|M.vanbaalenii_PYR-1 NALSTEMLSIMVDAWNRVDEDPEIRTCILTGAGGYFCAGMDLKAAS----
TH_1820|M.thermoresistible__bu NALSTEMLATMVEAWDRVDNDPEIRTCILTGAGGYFCSGMDLKAAT----
MLBr_00120|M.leprae_Br4923 NAMGPAFWSEMPEVFAELDTNREVRAVVITGSGKDFSYGLDVPAMGGKFV
*::. : : . : : .:* :: . * * *:*:
MSMEG_3362|M.smegmatis_MC2_155 -----PSLQDGSLQ--IPEGGINPWQVDGRRLTKPLVTAVHGKCLTLGIE
MAB_1493c|M.abscessus_ATCC_199 -----AEIQGGASL--TPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIE
MMAR_0471|M.marinum_M -----PSIAAGQSP--FPADGRDPWRLDG-PWRTPLIAVAHGWCMTLGIE
MUL_1121|M.ulcerans_Agy99 -----PSIAAGQSP--FPADGRDPWRLDG-PWRTPLIAVAHGWCMTLGIE
Mb3545|M.bovis_AF2122/97 -----QKPPGDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTE
Rv3516|M.tuberculosis_H37Rv -----QKPPGDSFKDGSYGPSRIDALLKGRRLTKPLIAAVEGPAIAGGTE
MAV_0643|M.avium_104 -----KKPPGESFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTE
Mflv_1542|M.gilvum_PYR-GCK -----SQAPGDSFKDGSYDPSKIPALLKGRRLKKPLIAAVEGAAIAGGTE
Mvan_5216|M.vanbaalenii_PYR-1 -----KKPPGDSFADGSYDPSKIEGLLKGRRLKKPLIAAVEGPAIAGGTE
TH_1820|M.thermoresistible__bu -----ARPPGDSFKDGSYDPSTIPALLKGRRLTKPLIAAVEGPAIAGGTE
MLBr_00120|M.leprae_Br4923 PLLTDGALARPRTDFHAEVLRMQKAINAVADCRTPTIAAVHGWCIGGALD
.* :....* : . :
MSMEG_3362|M.smegmatis_MC2_155 LLLASDIVVASESATFAQLEIARGIYPFGGATPRFPRVAGWGNAMRWMLT
MAB_1493c|M.abscessus_ATCC_199 LALAADIVIADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMRWMLT
MMAR_0471|M.marinum_M LLLASDIRIAAAGTRFSQLEVQRGIYPFGGATIRLTRDAGWGNAMRWLLT
MUL_1121|M.ulcerans_Agy99 LLLASDIRIAAAGTRFSQLEVQRGIYPFGGATIRLTRDAGWGNAMRWLLT
Mb3545|M.bovis_AF2122/97 ILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLT
Rv3516|M.tuberculosis_H37Rv ILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLT
MAV_0643|M.avium_104 ILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLT
Mflv_1542|M.gilvum_PYR-GCK ILQGTDIRVAGESAKFGVSEAKWSLYPMGGSAVRLVRQIPYTVACDILLT
Mvan_5216|M.vanbaalenii_PYR-1 ILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLPRQIPYTIACDLLLT
TH_1820|M.thermoresistible__bu ILQGTDIRIAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTIAADLLLT
MLBr_00120|M.leprae_Br4923 LISAVDIRYASADAKFSMREVKLAIVADMGSLARLPLILSDGHLRELALT
: . ** * : *. * .: . *: *: **
MSMEG_3362|M.smegmatis_MC2_155 AEEFDSAEALRIGVVQEVVDDG-AHIARAVQLAHVIA-AQAPLGVQATLR
MAB_1493c|M.abscessus_ATCC_199 ADTFDAVEAHRIGIVQEIVPVG-EHVDTAIAIAQTIA-RQAPLGVQATLR
MMAR_0471|M.marinum_M GDEFDAAEAHRIGLVQEVADDAATALTRAREIAQTIADRAAPLGVRATLA
MUL_1121|M.ulcerans_Agy99 GDEFDAAEAHRIGLVQEVADDAATALTRAREIAQTIADRAAPLGVRATLA
Mb3545|M.bovis_AF2122/97 GRHITAAEAKEMGLIGHVVPDG-QALTKALELADAIS-ANGPLAVQAILR
Rv3516|M.tuberculosis_H37Rv GRHITAAEAKEMGLIGHVVPDG-QALTKALELADAIS-ANGPLAVQAILR
MAV_0643|M.avium_104 GRHITAAEAKEMGLIGHVVPDG-QALAKALEIAEVIE-NNGPLAVQAILR
Mflv_1542|M.gilvum_PYR-GCK GRHISAAEAKEFGLIGHVVPDG-QALTKALEIAEVIN-GNGPLAVQAILK
Mvan_5216|M.vanbaalenii_PYR-1 GRHITAAEALQYGLIGHVVPDG-TALDKALEIAEVIN-NNGPLAVQAILK
TH_1820|M.thermoresistible__bu GRHITAAEAKEIGLIGYVVPDG-TALDKALEIAEVIN-NNGPLAVQAILR
MLBr_00120|M.leprae_Br4923 GKDIDATRAEKIGLVNDVYDNADKTLAAAHATAAEIA-ANPPLAVYGVKD
. : :..* . *:: : . : * * * **.* .
MSMEG_3362|M.smegmatis_MC2_155 SARLAQRDGEAAAEAELVPTIVKLFGTEDSRIGLESFATRRPAQFVGR
MAB_1493c|M.abscessus_ATCC_199 NARLAVREGDAAAEEQLVPTVRELFTSEDATLGVQAFLSRTTAEFVGR
MMAR_0471|M.marinum_M SAHLARREGEAAAIERLVPDIRALFTSADAAEGVQSFIERRQARFTGR
MUL_1121|M.ulcerans_Agy99 SVHLARREGEAAAIERLVPDIRALFTSADAAEGVQSFIERRQARFTGR
Mb3545|M.bovis_AF2122/97 SIRETECMPENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv SIRETECMPENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
MAV_0643|M.avium_104 AIRETEGMHENEAFKIDTQIGIKVFLSEDAKEGPRAFAEKRKPNFQNR
Mflv_1542|M.gilvum_PYR-GCK TIRETEGMHEEEAFKPDTANGIPVFLSEDSKEGPKAFLEKRKPVWKLK
Mvan_5216|M.vanbaalenii_PYR-1 TIRETEGMHEEEAFKPDTANGIPVFLSEDAKEGPRAFKEKRAPNFQMK
TH_1820|M.thermoresistible__bu SIRETEGLPENEAFKIDTKIGIEVFLSEDAKEGPRAFKEKRKPVFKMK
MLBr_00120|M.leprae_Br4923 VLYQQRTSAISESLRYVAAWNAAFLPSKDLTEGISATFAKRAPQFIGE
: . .: : * * : : . : .