For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SDYETLRIRRDGYVLVIGLNRPAKRNAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASV AAEIQGGASLTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVIADETATFAQLEVNRGIY PFGGATIRFPRTAGWGNAMRWMLTADTFDAVEAHRIGIVQEIVPVGEHVDTAIAIAQTIARQAPLGVQAT LRNARLAVREGDAAAEEQLVPTVRELFTSEDATLGVQAFLSRTTAEFVGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_1493c | - | - | 100% (261) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0836c | - | 2e-36 | 35.47% (265) | putative enoyl-CoA hydratase/isomerase |
| M. abscessus ATCC 19977 | MAB_4164 | - | 2e-33 | 34.26% (251) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3545 | echA19 | 1e-33 | 31.80% (261) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1542 | - | 9e-32 | 32.02% (253) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv3516 | echA19 | 2e-33 | 31.80% (261) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-26 | 31.58% (266) | enoyl-CoA hydratase |
| M. marinum M | MMAR_0471 | - | 6e-74 | 57.36% (258) | enoyl-CoA hydratase |
| M. avium 104 | MAV_0643 | - | 9e-34 | 32.95% (261) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_3362 | - | 6e-96 | 65.89% (258) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3131 | - | 5e-34 | 35.29% (255) | PUTATIVE putative enoyl-CoA hydratase EchA1 |
| M. ulcerans Agy99 | MUL_1121 | - | 5e-73 | 57.25% (255) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_5216 | - | 1e-32 | 32.95% (258) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1542|M.gilvum_PYR-GCK MLHFQTSLWHRRWKADQFVSDEQNPEKAPDALVEQRGHTLIVTMNRPEKR
Mvan_5216|M.vanbaalenii_PYR-1 ------------------MSD---PQKGPDALVEQRGHTLIVTLNRPEAR
Mb3545|M.bovis_AF2122/97 ------------------------MESGPDALVERRGHTLIVTMNRPAAR
Rv3516|M.tuberculosis_H37Rv ------------------------MESGPDALVERRGHTLIVTMNRPAAR
MAV_0643|M.avium_104 -----------------MAEASANEKTGPDALVEQRGHTLIVTLNRPHAR
MLBr_02402|M.leprae_Br4923 -------------------------MKYDTILVDGYQRVGIITLNRPQAL
TH_3131|M.thermoresistible__bu ----------------------------MIVEVRRQDRILVIAMNRPAKR
MAB_1493c|M.abscessus_ATCC_199 ------------------------MSDYETLRIRRDGYVLVIGLNRPAKR
MSMEG_3362|M.smegmatis_MC2_155 ----------------------MSFDRYETLAVTRDGAVLVIGLNRPDKR
MMAR_0471|M.marinum_M ---------------MQMTTTETSLPKLATVSLERDGHVLLIGLNRPQKR
MUL_1121|M.ulcerans_Agy99 ------------------------------MSLERDGHVLLIGLNRPQKR
: :: :***
Mflv_1542|M.gilvum_PYR-GCK NALSAEMMQIMVEAWDRVDSDPEIRSCILTGAGGAFCAGMDLKKADSQAP
Mvan_5216|M.vanbaalenii_PYR-1 NALSTEMLSIMVDAWNRVDEDPEIRTCILTGAGGYFCAGMDLKAASKKPP
Mb3545|M.bovis_AF2122/97 NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP
Rv3516|M.tuberculosis_H37Rv NALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPP
MAV_0643|M.avium_104 NALSTEMMEIMVQAWDRVDNDDDIRCCILTGAGGYFCAGMDLKAATKKPP
MLBr_02402|M.leprae_Br4923 NALNSQMMNEITNAAKELDIDPDVGAILITGSPKVFAAGADIKEMASLTF
TH_3131|M.thermoresistible__bu NAVNKEMAEALSAALDLMDDDDELWAGVLTGTREFFCAGTDLKDGADART
MAB_1493c|M.abscessus_ATCC_199 NAFDKTMLEELALALGEYETDTDLRAAVLYGEGPLFTAGLDLASVAAEIQ
MSMEG_3362|M.smegmatis_MC2_155 NAFNREMIGELAEVLGKLDSDDELRVGVLYGEGKGFTSGLDLPDVAPSLQ
MMAR_0471|M.marinum_M NSFDRAMFADLSRAYALLETDDSVRAGVLFAHGDHFTGGLDLVDVAPSIA
MUL_1121|M.ulcerans_Agy99 NSFDRAMFADLSRAYALLETDDSVRAGVLFAHGDHFTGGLDLVDVAPSIA
*:.. * : . : * .: :: . * .* *:
Mflv_1542|M.gilvum_PYR-GCK GDSFKDGSYDPSKIPALLKGRRLKKPLIAAVEGAAIAGGTEILQGTDIRV
Mvan_5216|M.vanbaalenii_PYR-1 GDSFADGSYDPSKIEGLLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRV
Mb3545|M.bovis_AF2122/97 GDSFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
Rv3516|M.tuberculosis_H37Rv GDSFKDGSYGPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
MAV_0643|M.avium_104 GESFKDGSYDPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRV
MLBr_02402|M.leprae_Br4923 TDAFDADFFS-----AWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLI
TH_3131|M.thermoresistible__bu ERGGEYGIIR----------RRRRKPLIAAVEGACFGGGMEIAFACDLVV
MAB_1493c|M.abscessus_ATCC_199 GGASL--TPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVI
MSMEG_3362|M.smegmatis_MC2_155 DGSLQ--IPEGGINPWQVDGRRLTKPLVTAVHGKCLTLGIELLLASDIVV
MMAR_0471|M.marinum_M AGQSP--FPADGRDPWRLDG-PWRTPLIAVAHGWCMTLGIELLLASDIRI
MUL_1121|M.ulcerans_Agy99 AGQSP--FPADGRDPWRLDG-PWRTPLIAVAHGWCMTLGIELLLASDIRI
.*::... * : * *: *: :
Mflv_1542|M.gilvum_PYR-GCK AGESAKFGVSEAKWSLYPMGGSAVRLVRQIPYTVACDILLTGRHISAAEA
Mvan_5216|M.vanbaalenii_PYR-1 AGESAKFGISEAKWSLYPMGGSAVRLPRQIPYTIACDLLLTGRHITAAEA
Mb3545|M.bovis_AF2122/97 AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA
Rv3516|M.tuberculosis_H37Rv AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEA
MAV_0643|M.avium_104 AGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA
MLBr_02402|M.leprae_Br4923 AADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEA
TH_3131|M.thermoresistible__bu AATTARFALPESRRGLVPSSGALLRATRSLPIHLAKELMITGAELSGERA
MAB_1493c|M.abscessus_ATCC_199 ADETATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMRWMLTADTFDAVEA
MSMEG_3362|M.smegmatis_MC2_155 ASESATFAQLEIARGIYPFGGATPRFPRVAGWGNAMRWMLTAEEFDSAEA
MMAR_0471|M.marinum_M AAAGTRFSQLEVQRGIYPFGGATIRLTRDAGWGNAMRWLLTGDEFDAAEA
MUL_1121|M.ulcerans_Agy99 AAAGTRFSQLEVQRGIYPFGGATIRLTRDAGWGNAMRWLLTGDEFDAAEA
* : *. * .: * *. * * * ::*. : . .*
Mflv_1542|M.gilvum_PYR-GCK KEFGLIGHVVPDG-QALTKALEIAEVIN-GNGPLAVQAILKTIRETEGMH
Mvan_5216|M.vanbaalenii_PYR-1 LQYGLIGHVVPDG-TALDKALEIAEVIN-NNGPLAVQAILKTIRETEGMH
Mb3545|M.bovis_AF2122/97 KEMGLIGHVVPDG-QALTKALELADAIS-ANGPLAVQAILRSIRETECMP
Rv3516|M.tuberculosis_H37Rv KEMGLIGHVVPDG-QALTKALELADAIS-ANGPLAVQAILRSIRETECMP
MAV_0643|M.avium_104 KEMGLIGHVVPDG-QALAKALEIAEVIE-NNGPLAVQAILRAIRETEGMH
MLBr_02402|M.leprae_Br4923 ERSGLVSRVVLAD-DLLPEAKAVATTIS-QMSRSATRMAKEAVNRSFEST
TH_3131|M.thermoresistible__bu HHFGLVNRIAEPG-AALEAAIDLAEDVC-QSSPTAVQAILEALADQLDEA
MAB_1493c|M.abscessus_ATCC_199 HRIGIVQEIVPVG-EHVDTAIAIAQTIA-RQAPLGVQATLRNARLAVREG
MSMEG_3362|M.smegmatis_MC2_155 LRIGVVQEVVDDG-AHIARAVQLAHVIA-AQAPLGVQATLRSARLAQRDG
MMAR_0471|M.marinum_M HRIGLVQEVADDAATALTRAREIAQTIADRAAPLGVRATLASAHLARREG
MUL_1121|M.ulcerans_Agy99 HRIGLVQEVADDAATALTRAREIAQTIADRAAPLGVRATLASVHLARREG
. *:: .:. : * :* : . ..:
Mflv_1542|M.gilvum_PYR-GCK EEEAFKPDTANGIPVFLSEDSKEGPKAFLEKRKPVWKLK
Mvan_5216|M.vanbaalenii_PYR-1 EEEAFKPDTANGIPVFLSEDAKEGPRAFKEKRAPNFQMK
Mb3545|M.bovis_AF2122/97 ENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
Rv3516|M.tuberculosis_H37Rv ENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
MAV_0643|M.avium_104 ENEAFKIDTQIGIKVFLSEDAKEGPRAFAEKRKPNFQNR
MLBr_02402|M.leprae_Br4923 LAEGLLHERRLFHSTFVTDDQSEGMAAFIEKRAPQFTHR
TH_3131|M.thermoresistible__bu DAVGWTATAKAVDRVVSSDDLQEGLAAFFERRPPRWVGR
MAB_1493c|M.abscessus_ATCC_199 DAAAEEQLVPTVRELFTSEDATLGVQAFLSRTTAEFVGR
MSMEG_3362|M.smegmatis_MC2_155 EAAAEAELVPTIVKLFGTEDSRIGLESFATRRPAQFVGR
MMAR_0471|M.marinum_M EAAAIERLVPDIRALFTSADAAEGVQSFIERRQARFTGR
MUL_1121|M.ulcerans_Agy99 EAAAIERLVPDIRALFTSADAAEGVQSFIERRQARFTGR
. . : * * :* : . : :