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DALDLSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTVWVATGNDTWYRLTRFFGKLFLINFAIGVATGIV QEFQFGMNWSEYSRFVGDIFGAPLAMEGLAAFFFESTFIGLWIFGWTRLPRWLHLACIWIVAIAVNLSAF FIISANSFMQHPVGARFNPETGRAELESIFALFTNNTAIAAFTHAVSGAFLTAGVFVACVCAWWMVRSHR TGGESAADAATMYRPATILGCWVTLVAAVALFFTGDAQGKLMFEQQPMKMASAESLCHSEQDPSFSVLTV GTHNNCDSVVHLIEVPYVLPFLAEGKFSGVHLDGVVDLQRSYEEKFGPGDYRPNLFVTYWSFRAMIGFLA VPGLFALAALWLTRGGRIPDQRWFSWFALLTIPTPFLANSAGWVFTEMGRQPWVVVPNPTGDQDIRLTVA QGVSDHSVGLVVLSLVAFTLVYAVLAVIWFFLLRRYIVQGPSEHDSEPAAPRPPDADDVAPLSFAY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3233 | - | - | 100% (487) | cytochrome D ubiquinol oxidase subunit 1 |
| M. smegmatis MC2 155 | MSMEG_5605 | - | 1e-33 | 27.83% (406) | cytochrome bd ubiquinol oxidase, subunit I |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1649c | cydA | 0.0 | 78.44% (487) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. gilvum PYR-GCK | Mflv_3585 | - | 0.0 | 77.02% (496) | cytochrome bd ubiquinol oxidase, subunit I |
| M. tuberculosis H37Rv | Rv1623c | cydA | 0.0 | 78.44% (487) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2630 | - | 0.0 | 73.72% (487) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. marinum M | MMAR_2426 | cydA | 0.0 | 77.00% (487) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. avium 104 | MAV_3164 | - | 0.0 | 76.73% (490) | cytochrome D ubiquinol oxidase subunit 1 |
| M. thermoresistible (build 8) | TH_1290 | appC | 0.0 | 77.82% (487) | Probable integral membrane cytochrome D ubiquinol oxidase |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2830 | - | 0.0 | 78.44% (487) | cytochrome bd ubiquinol oxidase, subunit I |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3585|M.gilvum_PYR-GCK MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTIWHFTGNTAWYRL
Mvan_2830|M.vanbaalenii_PYR-1 MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAIMQTVWHVTGNAAWYRL
TH_1290|M.thermoresistible__bu MDALDLSRWQFGITTVYHFIFVPLTIGLAPILAAMQTAWMVTGNTAWYRL
MSMEG_3233|M.smegmatis_MC2_155 MDALDLSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTVWVATGNDTWYRL
Mb1649c|M.bovis_AF2122/97 MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
Rv1623c|M.tuberculosis_H37Rv MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
MMAR_2426|M.marinum_M MNVVDVSRWQFGITTVYHFIFVPLTIGLAPLLAIMQTAWVITDNPAWYRL
MAV_3164|M.avium_104 MNVVDISRWQFGIVTVYHFIFVPLTIGLAPLLAIMQTAWVATGNTAWYRL
MAB_2630|M.abscessus_ATCC_1997 MNALDVSRWQFGITTVYHFILVPLTIGLAPLIAIMQTAWVVTGNNSWYRL
*:.:*:*******.******:*********::* *** * *.* :****
Mflv_3585|M.gilvum_PYR-GCK TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSKFVGDIFGAPLAFEGL
Mvan_2830|M.vanbaalenii_PYR-1 TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
TH_1290|M.thermoresistible__bu TRFFGKLFLINFALGVATGVVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
MSMEG_3233|M.smegmatis_MC2_155 TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
Mb1649c|M.bovis_AF2122/97 TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
Rv1623c|M.tuberculosis_H37Rv TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
MMAR_2426|M.marinum_M TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAV_3164|M.avium_104 TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAB_2630|M.abscessus_ATCC_1997 TKFFGKLFLINFALGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLALEGL
*:***********:*****:**************:****:******:***
Mflv_3585|M.gilvum_PYR-GCK IAFFFESTFIGLWIFGWSRLPRAVHLACIWIVAFGVNASAYFIIAANSFM
Mvan_2830|M.vanbaalenii_PYR-1 IAFFFESTFIGLWIFGWNRLPRVVHLACIWIVAFGVNASAYFIIAANSFM
TH_1290|M.thermoresistible__bu VAFFFESTFIGLWVFGWGRLNRWVHLACIWIVAFAVNASAYFIIAANSFM
MSMEG_3233|M.smegmatis_MC2_155 AAFFFESTFIGLWIFGWTRLPRWLHLACIWIVAIAVNLSAFFIISANSFM
Mb1649c|M.bovis_AF2122/97 AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
Rv1623c|M.tuberculosis_H37Rv AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
MMAR_2426|M.marinum_M MAFFFESTFIGLWIFGWSRLPRLVHLACIWIVAISVNVSAFFIITANSFM
MAV_3164|M.avium_104 FAFFFESTFIGLWIFGWGRLPKLIHLACIWIVAIGVNASAFFIIAANSFM
MAB_2630|M.abscessus_ATCC_1997 VAFFLESTFLGLWIFGWTRLPKLVHLACIWMVAIGVNASAFFIIAANSFM
***:****:***:*** ** : :******:**:.** **:***:*****
Mflv_3585|M.gilvum_PYR-GCK QHPVGARYNPESGRAELVDFGALLTNNTAIWASLHAIAGALLTAGAFVAG
Mvan_2830|M.vanbaalenii_PYR-1 QHPVGAKFNPETGRAELVDFGALLTNNTAIWAFLHAITASLLTAGAFVAG
TH_1290|M.thermoresistible__bu QHPVGARFNPETGRAELENFVALLTNNTAIWAFLHAVAASFLTAGAFVAG
MSMEG_3233|M.smegmatis_MC2_155 QHPVGARFNPETGRAELESIFALFTNNTAIAAFTHAVSGAFLTAGVFVAC
Mb1649c|M.bovis_AF2122/97 QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
Rv1623c|M.tuberculosis_H37Rv QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
MMAR_2426|M.marinum_M QHPVGAHYNPETHRAELNSIVALLTNNTGRTAFAHTVTGAFLTAGTFVAA
MAV_3164|M.avium_104 QHPVGAHYNPATRRAELDDIFALLSNNTAQAAFSHTVTGALLTAGTFVAA
MAB_2630|M.abscessus_ATCC_1997 QHPVGAVYNPETGRAELTSITELLTNNTALAAFPHTVAGSLLTAGTFIAG
****** :** : **** .: *::***. * *:::.::****.*:*
Mflv_3585|M.gilvum_PYR-GCK VSAWLMVRERRRDRDMADPDVAPTSSLVAHSMFRPAAILGSFVALVAAGG
Mvan_2830|M.vanbaalenii_PYR-1 ICAWLMVRAHRRGG----------EEVEARTMYRPATILGSAVALVAAAG
TH_1290|M.thermoresistible__bu VCAWLMVRSHRNPD----------ESAPAPTLYRPATIASCVVVLVSSVA
MSMEG_3233|M.smegmatis_MC2_155 VCAWWMVRSHRTGGE---------SAADAATMYRPATILGCWVTLVAAVA
Mb1649c|M.bovis_AF2122/97 VSAWWLVRS-----------STTHADSDTQAMYRPATILGCWVALAATAG
Rv1623c|M.tuberculosis_H37Rv VSAWWLVRS-----------STTHADSDTQAMYRPATILGCWVALAATAG
MMAR_2426|M.marinum_M VSAWWLVRS-----------KNSPVPPGTRAMYRPATILGCWVALIATVG
MAV_3164|M.avium_104 VSAWWMVRSRAGGS------TTPAAETEARTMFRPAAILGCGVVLLATVA
MAB_2630|M.abscessus_ATCC_1997 ICGWWMVRSHKVG-----------TLDDARTMYRPAAIGACAVMILSGVA
:..* :** : :::***:* .. * : : .
Mflv_3585|M.gilvum_PYR-GCK LFFTGDIQGKLMFVQQPMKMASAESLCHTETDPDFSILTVGTHNNCDSVT
Mvan_2830|M.vanbaalenii_PYR-1 LFFTGDIQGKLMFVQQPMKMASAESLCNTETDPNFSILTVGTHNNCDGIV
TH_1290|M.thermoresistible__bu LFFTGDIQGKLMFVQQPMKMASAESLCYTATDPGFSVLTVGRHNNCDSVV
MSMEG_3233|M.smegmatis_MC2_155 LFFTGDAQGKLMFEQQPMKMASAESLCHSEQDPSFSVLTVGTHNNCDSVV
Mb1649c|M.bovis_AF2122/97 LLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNCDSLT
Rv1623c|M.tuberculosis_H37Rv LLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNCDSLT
MMAR_2426|M.marinum_M LFFSGDYQGKLMFQQQPMKMASAESLCDTQTDPNFSILTVGRQNNCDGLT
MAV_3164|M.avium_104 LFFTGDRQGKLIFVQQPMKMASAESLCHTQTDPDFSVLTIGTHNNCGSVT
MAB_2630|M.abscessus_ATCC_1997 LAATGDVQGKLMFQQQPMKMASAESLCYTEKDPKFSVLTVGTHNNCASVT
* :** ****:* ************* : ** **:**:* :*** .:.
Mflv_3585|M.gilvum_PYR-GCK HLIEVPYVLPFLAESKFSGVTLEGVQDLQEQYQEKFGPGDYRPNLFVTYW
Mvan_2830|M.vanbaalenii_PYR-1 RVLEVPYVLPFLAESKFSGVTLEGVEDLQQAAEQKFGPGNYRPNLFVTYW
TH_1290|M.thermoresistible__bu HLIEVPYVLPFLAEGTFSGVTLEGVEDLQQQYEQRFGPGNYRPNLFVTYW
MSMEG_3233|M.smegmatis_MC2_155 HLIEVPYVLPFLAEGKFSGVHLDGVVDLQRSYEEKFGPGDYRPNLFVTYW
Mb1649c|M.bovis_AF2122/97 RVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLFVTYW
Rv1623c|M.tuberculosis_H37Rv RVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLFVTYW
MMAR_2426|M.marinum_M RVIEVPYVLPILAQGRPTNVTLQGVRDLQRDYQQRFGPNDYRPNLFVTYW
MAV_3164|M.avium_104 EVIKVHYVLPWLAEGRFSGVTLRGVNELQQQYQQRFGPDDYRPNLFVTYW
MAB_2630|M.abscessus_ATCC_1997 HAISLPYVLPFLAEGKFTDVTLKGVEDLQKEYEQKFGPRNYRPNLFVTYW
. :.: **** **:. :.* * *: :**. :::*** :**********
Mflv_3585|M.gilvum_PYR-GCK SFRAMIGLLLVPVAFALVTLWLTRRGRIPDQRWYGRFGILTIPTPFLANS
Mvan_2830|M.vanbaalenii_PYR-1 AFRAMIGLLLVPVAFALLSLWLTRRGRIPGQRWYGTFGLLTIPTPFLASS
TH_1290|M.thermoresistible__bu SFRAMIGLMLVPVAFALVALWLTRRGRIPHQLWFGRFGIATIPTPFLASS
MSMEG_3233|M.smegmatis_MC2_155 SFRAMIGFLAVPGLFALAALWLTRGGRIPDQRWFSWFALLTIPTPFLANS
Mb1649c|M.bovis_AF2122/97 SFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPFLANS
Rv1623c|M.tuberculosis_H37Rv SFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPFLANS
MMAR_2426|M.marinum_M SFRAMIGFLAIPVLFALLALWLTRGGRIPDKRWFGWFALLTIPTPFLANI
MAV_3164|M.avium_104 SFRLMIGFLAIPVLFALTVLWVTRRGRTPRQRWMSWFALLTIPTPFLANI
MAB_2630|M.abscessus_ATCC_1997 SFRAMIGLAAGSALLALAGLWVTRRGRIPGQRWFAWLSILAIPTPFLANS
:** ***: . :** **:** *: * : * . :.: ::*:****.
Mflv_3585|M.gilvum_PYR-GCK AGWVFTEMGRQPWVVVPNPTGDPLVRMTVQEGVSNHAAGTVWVSLTVFTL
Mvan_2830|M.vanbaalenii_PYR-1 AGWVFTEMGRQPWVVVPNPTGDQMVRMTVQEGVSNHAAGTVMFSLAVFTL
TH_1290|M.thermoresistible__bu AGWIFTEMGRQPWVVVPAPDGDELVRLTVQEGVSGHAPGTVLFSLTVFTL
MSMEG_3233|M.smegmatis_MC2_155 AGWVFTEMGRQPWVVVPNPTGDQDIRLTVAQGVSDHSVGLVVLSLVAFTL
Mb1649c|M.bovis_AF2122/97 AGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLLMFTL
Rv1623c|M.tuberculosis_H37Rv AGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLLMFTL
MMAR_2426|M.marinum_M SGWVFTEMGRQPWIVAPNPTGDPNVRLTVATAVSNLTTATVVTSLVTFTL
MAV_3164|M.avium_104 AGWVFTEMGRQPWVVVPNPTGDQAVRMTVREGVSNHVPGMVITSLATFTL
MAB_2630|M.abscessus_ATCC_1997 AGWVFTEMGRQPWVVAPNPTGVDQIRLTVDMAVSHHSAATVWLSLITFTL
:**:*********:*.* * * :*:** .** * ** ***
Mflv_3585|M.gilvum_PYR-GCK LYGALAVAWFYLMRRYVVEGPLEHDSEPAPPSPPDKDDVAPLSFAY
Mvan_2830|M.vanbaalenii_PYR-1 LYGALAVVWFYLLRRYVVEGPQEHDSEPAPPTPPSKDDVAPLSFAY
TH_1290|M.thermoresistible__bu IYGVLAVIWFWLMRRYVVEGPQEHDSEPVPPSPPGDDEMAQLSFAY
MSMEG_3233|M.smegmatis_MC2_155 VYAVLAVIWFFLLRRYIVQGPSEHDSEPAAPRPPDADDVAPLSFAY
Mb1649c|M.bovis_AF2122/97 VYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
Rv1623c|M.tuberculosis_H37Rv VYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
MMAR_2426|M.marinum_M VYAVLAVIWFWLLKRYIVEGPLEHDAEPAPPRAPDDDEVAPLSFAY
MAV_3164|M.avium_104 VYAVLAVVWFFLLKRYTVEGPLEHDAEPAPPRAPSDDEVAPLSFAY
MAB_2630|M.abscessus_ATCC_1997 LYGALGVVWFWLIRRYTIEGPLEHDAEPSPP-ASDDDSVKPLSFAY
:*..*.* * :*::** ::** ***:** . .. *.: *****