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M. thermoresistible (build 8) TH_1290 (appC)

annotation: Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) cydA (Cytochrome BD-I oxidase subunit I)
coordinates: 2450931 - 2452391
length: 487

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1290appC-100% (487)Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) cydA (Cytochrome BD-I oxidase subunit I)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1649ccydA0.072.39% (489) integral membrane cytochrome D ubiquinol oxidase (subunit I)
M. gilvum PYR-GCKMflv_3585-0.079.84% (496) cytochrome bd ubiquinol oxidase, subunit I
M. tuberculosis H37RvRv1623ccydA0.072.39% (489) integral membrane cytochrome D ubiquinol oxidase (subunit I)
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2630-0.071.81% (486) integral membrane cytochrome D ubiquinol oxidase (subunit I)
M. marinum MMMAR_2426cydA0.071.72% (488) integral membrane cytochrome D ubiquinol oxidase (subunit I)
M. avium 104MAV_3164-0.072.45% (490) cytochrome D ubiquinol oxidase subunit 1
M. smegmatis MC2 155MSMEG_3233-0.077.82% (487) cytochrome D ubiquinol oxidase subunit 1
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_2830-0.081.89% (486) cytochrome bd ubiquinol oxidase, subunit I

CLUSTAL 2.0.9 multiple sequence alignment


Mb1649c|M.bovis_AF2122/97           MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
Rv1623c|M.tuberculosis_H37Rv        MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
MMAR_2426|M.marinum_M               MNVVDVSRWQFGITTVYHFIFVPLTIGLAPLLAIMQTAWVITDNPAWYRL
MAV_3164|M.avium_104                MNVVDISRWQFGIVTVYHFIFVPLTIGLAPLLAIMQTAWVATGNTAWYRL
Mflv_3585|M.gilvum_PYR-GCK          MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTIWHFTGNTAWYRL
Mvan_2830|M.vanbaalenii_PYR-1       MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAIMQTVWHVTGNAAWYRL
TH_1290|M.thermoresistible__bu      MDALDLSRWQFGITTVYHFIFVPLTIGLAPILAAMQTAWMVTGNTAWYRL
MSMEG_3233|M.smegmatis_MC2_155      MDALDLSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTVWVATGNDTWYRL
MAB_2630|M.abscessus_ATCC_1997      MNALDVSRWQFGITTVYHFILVPLTIGLAPLIAIMQTAWVVTGNNSWYRL
                                    *:.:*:*******.******:*********::* *** *  *.* :****

Mb1649c|M.bovis_AF2122/97           TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
Rv1623c|M.tuberculosis_H37Rv        TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
MMAR_2426|M.marinum_M               TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAV_3164|M.avium_104                TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
Mflv_3585|M.gilvum_PYR-GCK          TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSKFVGDIFGAPLAFEGL
Mvan_2830|M.vanbaalenii_PYR-1       TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
TH_1290|M.thermoresistible__bu      TRFFGKLFLINFALGVATGVVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
MSMEG_3233|M.smegmatis_MC2_155      TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAB_2630|M.abscessus_ATCC_1997      TKFFGKLFLINFALGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLALEGL
                                    *:***********:*****:**************:****:******:***

Mb1649c|M.bovis_AF2122/97           AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
Rv1623c|M.tuberculosis_H37Rv        AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
MMAR_2426|M.marinum_M               MAFFFESTFIGLWIFGWSRLPRLVHLACIWIVAISVNVSAFFIITANSFM
MAV_3164|M.avium_104                FAFFFESTFIGLWIFGWGRLPKLIHLACIWIVAIGVNASAFFIIAANSFM
Mflv_3585|M.gilvum_PYR-GCK          IAFFFESTFIGLWIFGWSRLPRAVHLACIWIVAFGVNASAYFIIAANSFM
Mvan_2830|M.vanbaalenii_PYR-1       IAFFFESTFIGLWIFGWNRLPRVVHLACIWIVAFGVNASAYFIIAANSFM
TH_1290|M.thermoresistible__bu      VAFFFESTFIGLWVFGWGRLNRWVHLACIWIVAFAVNASAYFIIAANSFM
MSMEG_3233|M.smegmatis_MC2_155      AAFFFESTFIGLWIFGWTRLPRWLHLACIWIVAIAVNLSAFFIISANSFM
MAB_2630|M.abscessus_ATCC_1997      VAFFLESTFLGLWIFGWTRLPKLVHLACIWMVAIGVNASAFFIIAANSFM
                                     ***:****:***:*** ** : :******:**:.** **:***:*****

Mb1649c|M.bovis_AF2122/97           QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
Rv1623c|M.tuberculosis_H37Rv        QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
MMAR_2426|M.marinum_M               QHPVGAHYNPETHRAELNSIVALLTNNTGRTAFAHTVTGAFLTAGTFVAA
MAV_3164|M.avium_104                QHPVGAHYNPATRRAELDDIFALLSNNTAQAAFSHTVTGALLTAGTFVAA
Mflv_3585|M.gilvum_PYR-GCK          QHPVGARYNPESGRAELVDFGALLTNNTAIWASLHAIAGALLTAGAFVAG
Mvan_2830|M.vanbaalenii_PYR-1       QHPVGAKFNPETGRAELVDFGALLTNNTAIWAFLHAITASLLTAGAFVAG
TH_1290|M.thermoresistible__bu      QHPVGARFNPETGRAELENFVALLTNNTAIWAFLHAVAASFLTAGAFVAG
MSMEG_3233|M.smegmatis_MC2_155      QHPVGARFNPETGRAELESIFALFTNNTAIAAFTHAVSGAFLTAGVFVAC
MAB_2630|M.abscessus_ATCC_1997      QHPVGAVYNPETGRAELTSITELLTNNTALAAFPHTVAGSLLTAGTFIAG
                                    ****** :** : **** .:  *::***.  *  *:::.::****.*:* 

Mb1649c|M.bovis_AF2122/97           VSAWWLVRS-----STTH----------ADSDTQAMYRPATILGCWVALA
Rv1623c|M.tuberculosis_H37Rv        VSAWWLVRS-----STTH----------ADSDTQAMYRPATILGCWVALA
MMAR_2426|M.marinum_M               VSAWWLVRS-----KNSP----------VPPGTRAMYRPATILGCWVALI
MAV_3164|M.avium_104                VSAWWMVRSRAGGSTTPA----------AETEARTMFRPAAILGCGVVLL
Mflv_3585|M.gilvum_PYR-GCK          VSAWLMVRER----RRDRDMADPDVAPTSSLVAHSMFRPAAILGSFVALV
Mvan_2830|M.vanbaalenii_PYR-1       ICAWLMVRAH----RRGG----------EEVEARTMYRPATILGSAVALV
TH_1290|M.thermoresistible__bu      VCAWLMVRSH----RNPD----------ESAPAPTLYRPATIASCVVVLV
MSMEG_3233|M.smegmatis_MC2_155      VCAWWMVRSH----RTGGE---------SAADAATMYRPATILGCWVTLV
MAB_2630|M.abscessus_ATCC_1997      ICGWWMVRSH-----KVG----------TLDDARTMYRPAAIGACAVMIL
                                    :..* :**                        : :::***:* .. * : 

Mb1649c|M.bovis_AF2122/97           ATAGLLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNC
Rv1623c|M.tuberculosis_H37Rv        ATAGLLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNC
MMAR_2426|M.marinum_M               ATVGLFFSGDYQGKLMFQQQPMKMASAESLCDTQTDPNFSILTVGRQNNC
MAV_3164|M.avium_104                ATVALFFTGDRQGKLIFVQQPMKMASAESLCHTQTDPDFSVLTIGTHNNC
Mflv_3585|M.gilvum_PYR-GCK          AAGGLFFTGDIQGKLMFVQQPMKMASAESLCHTETDPDFSILTVGTHNNC
Mvan_2830|M.vanbaalenii_PYR-1       AAAGLFFTGDIQGKLMFVQQPMKMASAESLCNTETDPNFSILTVGTHNNC
TH_1290|M.thermoresistible__bu      SSVALFFTGDIQGKLMFVQQPMKMASAESLCYTATDPGFSVLTVGRHNNC
MSMEG_3233|M.smegmatis_MC2_155      AAVALFFTGDAQGKLMFEQQPMKMASAESLCHSEQDPSFSVLTVGTHNNC
MAB_2630|M.abscessus_ATCC_1997      SGVALAATGDVQGKLMFQQQPMKMASAESLCYTEKDPKFSVLTVGTHNNC
                                    :  .*  :** ****:* ************* :  ** **:**:* :***

Mb1649c|M.bovis_AF2122/97           DSLTRVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLF
Rv1623c|M.tuberculosis_H37Rv        DSLTRVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLF
MMAR_2426|M.marinum_M               DGLTRVIEVPYVLPILAQGRPTNVTLQGVRDLQRDYQQRFGPNDYRPNLF
MAV_3164|M.avium_104                GSVTEVIKVHYVLPWLAEGRFSGVTLRGVNELQQQYQQRFGPDDYRPNLF
Mflv_3585|M.gilvum_PYR-GCK          DSVTHLIEVPYVLPFLAESKFSGVTLEGVQDLQEQYQEKFGPGDYRPNLF
Mvan_2830|M.vanbaalenii_PYR-1       DGIVRVLEVPYVLPFLAESKFSGVTLEGVEDLQQAAEQKFGPGNYRPNLF
TH_1290|M.thermoresistible__bu      DSVVHLIEVPYVLPFLAEGTFSGVTLEGVEDLQQQYEQRFGPGNYRPNLF
MSMEG_3233|M.smegmatis_MC2_155      DSVVHLIEVPYVLPFLAEGKFSGVHLDGVVDLQRSYEEKFGPGDYRPNLF
MAB_2630|M.abscessus_ATCC_1997      ASVTHAISLPYVLPFLAEGKFTDVTLKGVEDLQKEYEQKFGPRNYRPNLF
                                     .:.. :.: **** **:.  :.* * *: :**.  :::*** :******

Mb1649c|M.bovis_AF2122/97           VTYWSFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPF
Rv1623c|M.tuberculosis_H37Rv        VTYWSFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPF
MMAR_2426|M.marinum_M               VTYWSFRAMIGFLAIPVLFALLALWLTRGGRIPDKRWFGWFALLTIPTPF
MAV_3164|M.avium_104                VTYWSFRLMIGFLAIPVLFALTVLWVTRRGRTPRQRWMSWFALLTIPTPF
Mflv_3585|M.gilvum_PYR-GCK          VTYWSFRAMIGLLLVPVAFALVTLWLTRRGRIPDQRWYGRFGILTIPTPF
Mvan_2830|M.vanbaalenii_PYR-1       VTYWAFRAMIGLLLVPVAFALLSLWLTRRGRIPGQRWYGTFGLLTIPTPF
TH_1290|M.thermoresistible__bu      VTYWSFRAMIGLMLVPVAFALVALWLTRRGRIPHQLWFGRFGIATIPTPF
MSMEG_3233|M.smegmatis_MC2_155      VTYWSFRAMIGFLAVPGLFALAALWLTRGGRIPDQRWFSWFALLTIPTPF
MAB_2630|M.abscessus_ATCC_1997      VTYWSFRAMIGLAAGSALLALAGLWVTRRGRIPGQRWFAWLSILAIPTPF
                                    ****:** ***:   .  :**  **:** *: * : * . :.: ::*:**

Mb1649c|M.bovis_AF2122/97           LANSAGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLL
Rv1623c|M.tuberculosis_H37Rv        LANSAGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLL
MMAR_2426|M.marinum_M               LANISGWVFTEMGRQPWIVAPNPTGDPNVRLTVATAVSNLTTATVVTSLV
MAV_3164|M.avium_104                LANIAGWVFTEMGRQPWVVVPNPTGDQAVRMTVREGVSNHVPGMVITSLA
Mflv_3585|M.gilvum_PYR-GCK          LANSAGWVFTEMGRQPWVVVPNPTGDPLVRMTVQEGVSNHAAGTVWVSLT
Mvan_2830|M.vanbaalenii_PYR-1       LASSAGWVFTEMGRQPWVVVPNPTGDQMVRMTVQEGVSNHAAGTVMFSLA
TH_1290|M.thermoresistible__bu      LASSAGWIFTEMGRQPWVVVPAPDGDELVRLTVQEGVSGHAPGTVLFSLT
MSMEG_3233|M.smegmatis_MC2_155      LANSAGWVFTEMGRQPWVVVPNPTGDQDIRLTVAQGVSDHSVGLVVLSLV
MAB_2630|M.abscessus_ATCC_1997      LANSAGWVFTEMGRQPWVVAPNPTGVDQIRLTVDMAVSHHSAATVWLSLI
                                    **. :**:*********:*.* * *   :*:**  .**      *  ** 

Mb1649c|M.bovis_AF2122/97           MFTLVYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
Rv1623c|M.tuberculosis_H37Rv        MFTLVYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
MMAR_2426|M.marinum_M               TFTLVYAVLAVIWFWLLKRYIVEGPLEHDAEPAPPRAPDDDEVAPLSFAY
MAV_3164|M.avium_104                TFTLVYAVLAVVWFFLLKRYTVEGPLEHDAEPAPPRAPSDDEVAPLSFAY
Mflv_3585|M.gilvum_PYR-GCK          VFTLLYGALAVAWFYLMRRYVVEGPLEHDSEPAPPSPPDKDDVAPLSFAY
Mvan_2830|M.vanbaalenii_PYR-1       VFTLLYGALAVVWFYLLRRYVVEGPQEHDSEPAPPTPPSKDDVAPLSFAY
TH_1290|M.thermoresistible__bu      VFTLIYGVLAVIWFWLMRRYVVEGPQEHDSEPVPPSPPGDDEMAQLSFAY
MSMEG_3233|M.smegmatis_MC2_155      AFTLVYAVLAVIWFFLLRRYIVQGPSEHDSEPAAPRPPDADDVAPLSFAY
MAB_2630|M.abscessus_ATCC_1997      TFTLLYGALGVVWFWLIRRYTIEGPLEHDAEPSPP-ASDDDSVKPLSFAY
                                     ***:*..*.* * :*::** ::** ***:** .  ..  *.:  *****