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DALDVSRWQFGITTVYHFIFVPLTIGLAPLIAIMQTVWHVTGNAAWYRLTRFFGKLFLINFAIGVATGIV QEFQFGMNWSEYSRFVGDIFGAPLAFEGLIAFFFESTFIGLWIFGWNRLPRVVHLACIWIVAFGVNASAY FIIAANSFMQHPVGAKFNPETGRAELVDFGALLTNNTAIWAFLHAITASLLTAGAFVAGICAWLMVRAHR RGGEEVEARTMYRPATILGSAVALVAAAGLFFTGDIQGKLMFVQQPMKMASAESLCNTETDPNFSILTVG THNNCDGIVRVLEVPYVLPFLAESKFSGVTLEGVEDLQQAAEQKFGPGNYRPNLFVTYWAFRAMIGLLLV PVAFALLSLWLTRRGRIPGQRWYGTFGLLTIPTPFLASSAGWVFTEMGRQPWVVVPNPTGDQMVRMTVQE GVSNHAAGTVMFSLAVFTLLYGALAVVWFYLLRRYVVEGPQEHDSEPAPPTPPSKDDVAPLSFAY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2830 | - | - | 100% (486) | cytochrome bd ubiquinol oxidase, subunit I |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1649c | cydA | 0.0 | 73.46% (486) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. gilvum PYR-GCK | Mflv_3585 | - | 0.0 | 85.28% (496) | cytochrome bd ubiquinol oxidase, subunit I |
| M. tuberculosis H37Rv | Rv1623c | cydA | 0.0 | 73.46% (486) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2630 | - | 0.0 | 73.05% (486) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. marinum M | MMAR_2426 | cydA | 0.0 | 73.46% (486) | integral membrane cytochrome D ubiquinol oxidase (subunit I) |
| M. avium 104 | MAV_3164 | - | 0.0 | 75.15% (491) | cytochrome D ubiquinol oxidase subunit 1 |
| M. smegmatis MC2 155 | MSMEG_3233 | - | 0.0 | 78.44% (487) | cytochrome D ubiquinol oxidase subunit 1 |
| M. thermoresistible (build 8) | TH_1290 | appC | 0.0 | 81.89% (486) | Probable integral membrane cytochrome D ubiquinol oxidase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1649c|M.bovis_AF2122/97 MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
Rv1623c|M.tuberculosis_H37Rv MNVVDISRWQFGITTVYHFIFVPLTIGLAPLIAVMQTLWVVTDNPAWYRL
MMAR_2426|M.marinum_M MNVVDVSRWQFGITTVYHFIFVPLTIGLAPLLAIMQTAWVITDNPAWYRL
MAV_3164|M.avium_104 MNVVDISRWQFGIVTVYHFIFVPLTIGLAPLLAIMQTAWVATGNTAWYRL
Mvan_2830|M.vanbaalenii_PYR-1 MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAIMQTVWHVTGNAAWYRL
Mflv_3585|M.gilvum_PYR-GCK MDALDVSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTIWHFTGNTAWYRL
TH_1290|M.thermoresistible__bu MDALDLSRWQFGITTVYHFIFVPLTIGLAPILAAMQTAWMVTGNTAWYRL
MSMEG_3233|M.smegmatis_MC2_155 MDALDLSRWQFGITTVYHFIFVPLTIGLAPLIAVMQTVWVATGNDTWYRL
MAB_2630|M.abscessus_ATCC_1997 MNALDVSRWQFGITTVYHFILVPLTIGLAPLIAIMQTAWVVTGNNSWYRL
*:.:*:*******.******:*********::* *** * *.* :****
Mb1649c|M.bovis_AF2122/97 TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
Rv1623c|M.tuberculosis_H37Rv TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLAMEGL
MMAR_2426|M.marinum_M TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAV_3164|M.avium_104 TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
Mvan_2830|M.vanbaalenii_PYR-1 TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
Mflv_3585|M.gilvum_PYR-GCK TKFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSKFVGDIFGAPLAFEGL
TH_1290|M.thermoresistible__bu TRFFGKLFLINFALGVATGVVQEFQFGMNWSEYSRFVGDIFGAPLAFEGL
MSMEG_3233|M.smegmatis_MC2_155 TRFFGKLFLINFAIGVATGIVQEFQFGMNWSEYSRFVGDIFGAPLAMEGL
MAB_2630|M.abscessus_ATCC_1997 TKFFGKLFLINFALGVATGIVQEFQFGMNWSEYSRFVGDVFGAPLALEGL
*:***********:*****:**************:****:******:***
Mb1649c|M.bovis_AF2122/97 AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
Rv1623c|M.tuberculosis_H37Rv AAFFFESTFIGLWIFGWNRLPRLVHLACIWIVAIAVNVSAFFIIAANSFM
MMAR_2426|M.marinum_M MAFFFESTFIGLWIFGWSRLPRLVHLACIWIVAISVNVSAFFIITANSFM
MAV_3164|M.avium_104 FAFFFESTFIGLWIFGWGRLPKLIHLACIWIVAIGVNASAFFIIAANSFM
Mvan_2830|M.vanbaalenii_PYR-1 IAFFFESTFIGLWIFGWNRLPRVVHLACIWIVAFGVNASAYFIIAANSFM
Mflv_3585|M.gilvum_PYR-GCK IAFFFESTFIGLWIFGWSRLPRAVHLACIWIVAFGVNASAYFIIAANSFM
TH_1290|M.thermoresistible__bu VAFFFESTFIGLWVFGWGRLNRWVHLACIWIVAFAVNASAYFIIAANSFM
MSMEG_3233|M.smegmatis_MC2_155 AAFFFESTFIGLWIFGWTRLPRWLHLACIWIVAIAVNLSAFFIISANSFM
MAB_2630|M.abscessus_ATCC_1997 VAFFLESTFLGLWIFGWTRLPKLVHLACIWMVAIGVNASAFFIIAANSFM
***:****:***:*** ** : :******:**:.** **:***:*****
Mb1649c|M.bovis_AF2122/97 QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
Rv1623c|M.tuberculosis_H37Rv QHPVGAHYNPTTGRAELSSIVVLLTNNTAQAAFTHTVSGALLTAGTFVAA
MMAR_2426|M.marinum_M QHPVGAHYNPETHRAELNSIVALLTNNTGRTAFAHTVTGAFLTAGTFVAA
MAV_3164|M.avium_104 QHPVGAHYNPATRRAELDDIFALLSNNTAQAAFSHTVTGALLTAGTFVAA
Mvan_2830|M.vanbaalenii_PYR-1 QHPVGAKFNPETGRAELVDFGALLTNNTAIWAFLHAITASLLTAGAFVAG
Mflv_3585|M.gilvum_PYR-GCK QHPVGARYNPESGRAELVDFGALLTNNTAIWASLHAIAGALLTAGAFVAG
TH_1290|M.thermoresistible__bu QHPVGARFNPETGRAELENFVALLTNNTAIWAFLHAVAASFLTAGAFVAG
MSMEG_3233|M.smegmatis_MC2_155 QHPVGARFNPETGRAELESIFALFTNNTAIAAFTHAVSGAFLTAGVFVAC
MAB_2630|M.abscessus_ATCC_1997 QHPVGAVYNPETGRAELTSITELLTNNTALAAFPHTVAGSLLTAGTFIAG
****** :** : **** .: *::***. * *:::.::****.*:*
Mb1649c|M.bovis_AF2122/97 VSAWWLVRS-----STTH----------ADSDTQAMYRPATILGCWVALA
Rv1623c|M.tuberculosis_H37Rv VSAWWLVRS-----STTH----------ADSDTQAMYRPATILGCWVALA
MMAR_2426|M.marinum_M VSAWWLVRS-----KNSP----------VPPGTRAMYRPATILGCWVALI
MAV_3164|M.avium_104 VSAWWMVRSRAGGSTTPA----------AETEARTMFRPAAILGCGVVLL
Mvan_2830|M.vanbaalenii_PYR-1 ICAWLMVRAH----RRGG----------EEVEARTMYRPATILGSAVALV
Mflv_3585|M.gilvum_PYR-GCK VSAWLMVRER----RRDRDMADPDVAPTSSLVAHSMFRPAAILGSFVALV
TH_1290|M.thermoresistible__bu VCAWLMVRSH----RNPD----------ESAPAPTLYRPATIASCVVVLV
MSMEG_3233|M.smegmatis_MC2_155 VCAWWMVRSH----RTGGE---------SAADAATMYRPATILGCWVTLV
MAB_2630|M.abscessus_ATCC_1997 ICGWWMVRSH-----KVG----------TLDDARTMYRPAAIGACAVMIL
:..* :** : :::***:* .. * :
Mb1649c|M.bovis_AF2122/97 ATAGLLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNC
Rv1623c|M.tuberculosis_H37Rv ATAGLLFTGDHQGKLMFQQQPMKMASAESLCDTQTDPNFSVLTVGRQNNC
MMAR_2426|M.marinum_M ATVGLFFSGDYQGKLMFQQQPMKMASAESLCDTQTDPNFSILTVGRQNNC
MAV_3164|M.avium_104 ATVALFFTGDRQGKLIFVQQPMKMASAESLCHTQTDPDFSVLTIGTHNNC
Mvan_2830|M.vanbaalenii_PYR-1 AAAGLFFTGDIQGKLMFVQQPMKMASAESLCNTETDPNFSILTVGTHNNC
Mflv_3585|M.gilvum_PYR-GCK AAGGLFFTGDIQGKLMFVQQPMKMASAESLCHTETDPDFSILTVGTHNNC
TH_1290|M.thermoresistible__bu SSVALFFTGDIQGKLMFVQQPMKMASAESLCYTATDPGFSVLTVGRHNNC
MSMEG_3233|M.smegmatis_MC2_155 AAVALFFTGDAQGKLMFEQQPMKMASAESLCHSEQDPSFSVLTVGTHNNC
MAB_2630|M.abscessus_ATCC_1997 SGVALAATGDVQGKLMFQQQPMKMASAESLCYTEKDPKFSVLTVGTHNNC
: .* :** ****:* ************* : ** **:**:* :***
Mb1649c|M.bovis_AF2122/97 DSLTRVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLF
Rv1623c|M.tuberculosis_H37Rv DSLTRVIEVPYVLPFLAEGRISGVTLQGIRDLQQEYQQRFGPNDYRPNLF
MMAR_2426|M.marinum_M DGLTRVIEVPYVLPILAQGRPTNVTLQGVRDLQRDYQQRFGPNDYRPNLF
MAV_3164|M.avium_104 GSVTEVIKVHYVLPWLAEGRFSGVTLRGVNELQQQYQQRFGPDDYRPNLF
Mvan_2830|M.vanbaalenii_PYR-1 DGIVRVLEVPYVLPFLAESKFSGVTLEGVEDLQQAAEQKFGPGNYRPNLF
Mflv_3585|M.gilvum_PYR-GCK DSVTHLIEVPYVLPFLAESKFSGVTLEGVQDLQEQYQEKFGPGDYRPNLF
TH_1290|M.thermoresistible__bu DSVVHLIEVPYVLPFLAEGTFSGVTLEGVEDLQQQYEQRFGPGNYRPNLF
MSMEG_3233|M.smegmatis_MC2_155 DSVVHLIEVPYVLPFLAEGKFSGVHLDGVVDLQRSYEEKFGPGDYRPNLF
MAB_2630|M.abscessus_ATCC_1997 ASVTHAISLPYVLPFLAEGKFTDVTLKGVEDLQKEYEQKFGPRNYRPNLF
.:.. :.: **** **:. :.* * *: :**. :::*** :******
Mb1649c|M.bovis_AF2122/97 VTYWSFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPF
Rv1623c|M.tuberculosis_H37Rv VTYWSFRMMIGLMAIPVLFALIALWLTRGGQIPNQRWFSWLALLTMPAPF
MMAR_2426|M.marinum_M VTYWSFRAMIGFLAIPVLFALLALWLTRGGRIPDKRWFGWFALLTIPTPF
MAV_3164|M.avium_104 VTYWSFRLMIGFLAIPVLFALTVLWVTRRGRTPRQRWMSWFALLTIPTPF
Mvan_2830|M.vanbaalenii_PYR-1 VTYWAFRAMIGLLLVPVAFALLSLWLTRRGRIPGQRWYGTFGLLTIPTPF
Mflv_3585|M.gilvum_PYR-GCK VTYWSFRAMIGLLLVPVAFALVTLWLTRRGRIPDQRWYGRFGILTIPTPF
TH_1290|M.thermoresistible__bu VTYWSFRAMIGLMLVPVAFALVALWLTRRGRIPHQLWFGRFGIATIPTPF
MSMEG_3233|M.smegmatis_MC2_155 VTYWSFRAMIGFLAVPGLFALAALWLTRGGRIPDQRWFSWFALLTIPTPF
MAB_2630|M.abscessus_ATCC_1997 VTYWSFRAMIGLAAGSALLALAGLWVTRRGRIPGQRWFAWLSILAIPTPF
****:** ***: . :** **:** *: * : * . :.: ::*:**
Mb1649c|M.bovis_AF2122/97 LANSAGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLL
Rv1623c|M.tuberculosis_H37Rv LANSAGWVFTEMGRQPWVVVPNPTGDQLVRLTVKAGVSDHSATVVATSLL
MMAR_2426|M.marinum_M LANISGWVFTEMGRQPWIVAPNPTGDPNVRLTVATAVSNLTTATVVTSLV
MAV_3164|M.avium_104 LANIAGWVFTEMGRQPWVVVPNPTGDQAVRMTVREGVSNHVPGMVITSLA
Mvan_2830|M.vanbaalenii_PYR-1 LASSAGWVFTEMGRQPWVVVPNPTGDQMVRMTVQEGVSNHAAGTVMFSLA
Mflv_3585|M.gilvum_PYR-GCK LANSAGWVFTEMGRQPWVVVPNPTGDPLVRMTVQEGVSNHAAGTVWVSLT
TH_1290|M.thermoresistible__bu LASSAGWIFTEMGRQPWVVVPAPDGDELVRLTVQEGVSGHAPGTVLFSLT
MSMEG_3233|M.smegmatis_MC2_155 LANSAGWVFTEMGRQPWVVVPNPTGDQDIRLTVAQGVSDHSVGLVVLSLV
MAB_2630|M.abscessus_ATCC_1997 LANSAGWVFTEMGRQPWVVAPNPTGVDQIRLTVDMAVSHHSAATVWLSLI
**. :**:*********:*.* * * :*:** .** * **
Mb1649c|M.bovis_AF2122/97 MFTLVYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
Rv1623c|M.tuberculosis_H37Rv MFTLVYAVLAVIWCWLLKRYIVEGPLEHDAEPAAHGAPRDDEVAPLSFAY
MMAR_2426|M.marinum_M TFTLVYAVLAVIWFWLLKRYIVEGPLEHDAEPAPPRAPDDDEVAPLSFAY
MAV_3164|M.avium_104 TFTLVYAVLAVVWFFLLKRYTVEGPLEHDAEPAPPRAPSDDEVAPLSFAY
Mvan_2830|M.vanbaalenii_PYR-1 VFTLLYGALAVVWFYLLRRYVVEGPQEHDSEPAPPTPPSKDDVAPLSFAY
Mflv_3585|M.gilvum_PYR-GCK VFTLLYGALAVAWFYLMRRYVVEGPLEHDSEPAPPSPPDKDDVAPLSFAY
TH_1290|M.thermoresistible__bu VFTLIYGVLAVIWFWLMRRYVVEGPQEHDSEPVPPSPPGDDEMAQLSFAY
MSMEG_3233|M.smegmatis_MC2_155 AFTLVYAVLAVIWFFLLRRYIVQGPSEHDSEPAAPRPPDADDVAPLSFAY
MAB_2630|M.abscessus_ATCC_1997 TFTLLYGALGVVWFWLIRRYTIEGPLEHDAEPSPP-ASDDDSVKPLSFAY
***:*..*.* * :*::** ::** ***:** . .. *.: *****