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TTSHNTESTLSDPAVNTPLVPAVRMHDIVKTFPGTKACNGATLEVAPGEVHCLLGENGAGKSTMMKILSG SYTPDSGTIVIDGVETSFSSPIDGVRAGINTIYQELDLVPDLTVAQNLFLGHEPKRGPFVARRKRDRLAQ AAIERVGGSFAPSDVVANLSVADQQLTAIAKALTTDARVVIMDEPSAALTDHDLAAVFRVIRELTSAGKS VIYISHRLDEVKEIGDRATVMRDGATVGVFDIASVTKDELVEAMIGRGLQALPPRRSGPDGARTELLKVR RATIPGVLDVSDISVGRGEIVGLAGLGGAGRSTLLATLFGDRTATLDLTLNGVRLDRLTPRGAVAAGIGL VPEDRKSQGLFLEQSILRNAGIAALRPLRVNPMKAAEQLCMPALRRLGVKFAGLDQPVGQLSGGNQQKVV LAKWMARGIDLLLLDEPTRGLDIGAKGDLFEQVQALADSGVGVLMASSELSELTENCDLIWVMHEGRNIA AFDPRTTSATDIARCVVTGRHDND*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3091 | - | - | 100% (515) | ribose transport ATP-binding protein RbsA |
| M. smegmatis MC2 155 | MSMEG_3602 | - | 1e-91 | 38.22% (484) | ribose transport ATP-binding protein RbsA |
| M. smegmatis MC2 155 | MSMEG_4170 | - | 4e-90 | 39.64% (497) | ribose transport ATP-binding protein RbsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3784c | proV | 1e-21 | 26.78% (295) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. gilvum PYR-GCK | Mflv_2607 | - | 4e-32 | 34.48% (261) | ABC transporter related |
| M. tuberculosis H37Rv | Rv3758c | proV | 1e-21 | 26.78% (295) | osmoprotectant (glycine betaine/carnitine/choline/L-proline) |
| M. leprae Br4923 | MLBr_00590 | - | 2e-16 | 28.69% (251) | putative ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_2803c | - | 3e-28 | 30.19% (265) | methionine import ATP-binding protein metN |
| M. marinum M | MMAR_0171 | - | 5e-21 | 26.63% (338) | ATP-binding protein ABC transporter |
| M. avium 104 | MAV_0058 | - | 3e-22 | 29.69% (229) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_4070 | - | 9e-29 | 28.63% (510) | PUTATIVE ABC transporter related |
| M. ulcerans Agy99 | MUL_4925 | - | 7e-21 | 26.63% (338) | ATP-binding protein ABC transporter |
| M. vanbaalenii PYR-1 | Mvan_5292 | - | 5e-31 | 31.20% (234) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2607|M.gilvum_PYR-GCK ---MTISVEKASSDSKPGGKVPLVELKNIGKSYG-NITALKDISLRVHAG
Mvan_5292|M.vanbaalenii_PYR-1 ------------MDTQP----PILELRGVNKSFG-VVHVLHDVDFCVYPG
MAB_2803c|M.abscessus_ATCC_199 ------------MGDVAPLIQFQNVTKTFRVGKK-TVTAVDDVSLDIGSG
MAV_0058|M.avium_104 ------------MSNPASRASVSLACKDIHQTLN-GNAVLRGVDLDTPAG
Mb3784c|M.bovis_AF2122/97 ----------------------MICFDDVSKVYAHGATAVDRLTLEVPNG
Rv3758c|M.tuberculosis_H37Rv ----------------------MICFDDVSKVYAHGATAVDRLTLEVPNG
MMAR_0171|M.marinum_M -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPGSDANAVDGLNLVIPRG
MUL_4925|M.ulcerans_Agy99 -MSSPESKTDNETGDSQPGTSALEAVDLVKSYPGSDANAVDGLNLVIPRG
TH_4070|M.thermoresistible__bu -----------------VVTGPVLDVRDLRVRIG-RREIVRGVSFAVARG
MSMEG_3091|M.smegmatis_MC2_155 MTTSHNTESTLSDPAVNTPLVPAVRMHDIVKTFP-GTKACNGATLEVAPG
MLBr_00590|M.leprae_Br4923 ---------MSSACTVPETPEVVIRLRGVCKHYG-SILAVSNLDLDIHSA
. : .
Mflv_2607|M.gilvum_PYR-GCK EVTGILGDNGAGKSTLIKIIAGLHQQT----DGELLVDGEPTRFASPADA
Mvan_5292|M.vanbaalenii_PYR-1 QVTALVGDNGAGKSTLVKAIAGIHPID----TGTYLFEGKPVTVHSPNDV
MAB_2803c|M.abscessus_ATCC_199 DVFAMIGYSGAGKSTLVRLINGLERPT----SGRVIVDGAEVSALGEREL
MAV_0058|M.avium_104 STVAVIGPSGSGKSTLLRTLNRLYEPD----RGDILLDGRSVLHDDPDQL
Mb3784c|M.bovis_AF2122/97 MLTVFVGPSGCGKTTALRMINRMVDPT----SGTITVDGTDVSTVNAVKL
Rv3758c|M.tuberculosis_H37Rv MLTVFVGPSGCGKTTALRMINRMVDPT----SGTITVDGTDVSTVNAVKL
MMAR_0171|M.marinum_M VVYCLLGRNGAGKTTTIRMATTLLTPT----SGQLEVLG--VPVDNTTQL
MUL_4925|M.ulcerans_Agy99 VVYCLLGRNGAGKTTTIRMATTLLTPT----SGQLEVLG--VPVDNTTQL
TH_4070|M.thermoresistible__bu QTLGIVGESGSGKSMTVLAAAGLLDAPGAVVTGSATVGGVELIGAPPRLL
MSMEG_3091|M.smegmatis_MC2_155 EVHCLLGENGAGKSTMMKILSGSYTPD----SGTIVIDGVETSFSSPIDG
MLBr_00590|M.leprae_Br4923 EVLALLGPNGAGKTTTVEMCEGFVRPD----AGTIEVLGLDPITDNARLR
.:* .*.**: : * . *
Mflv_2607|M.gilvum_PYR-GCK LG---KGIATVYQN--LAVVPLMPVWRNFFLGQELRKKRFPFSLDANAMR
Mvan_5292|M.vanbaalenii_PYR-1 SA---LGVEVVYQD--LALCDNLDIVENMFLGRELKRRGMLDEARMETMA
MAB_2803c|M.abscessus_ATCC_199 RGLR-SDIGMIFQQ--FNLFRSRTVAGNIAYPLR-VAGWTADKRNARVAE
MAV_0058|M.avium_104 R----QRIGMVFQH--FNLFPHRTVLDNVALAPRKLRRLPAEAARELALT
Mb3784c|M.bovis_AF2122/97 R----LGIGYVIQN--AGLMPHQRVIDNVATVPVLKGQPRR-AARKAGYE
Rv3758c|M.tuberculosis_H37Rv R----LGIGYVIQN--AGLMPHQRVIDNVATVPVLKGQPRR-AARKAGYE
MMAR_0171|M.marinum_M R----PLIGVALQE--VALDLWMSPVEQIRMSLAMAGWPKS-DRKRREGE
MUL_4925|M.ulcerans_Agy99 R----PLIGVALQE--VALDLWMSPVEQIRMSLAMAGWPKS-DRKRREGE
TH_4070|M.thermoresistible__bu RSVHGNRVGFVFQDPGTSLNPLLTLERQITEVLEAHRGMTRRAARGRALE
MSMEG_3091|M.smegmatis_MC2_155 VR---AGINTIYQE--LDLVPDLTVAQNLFLGHEPKRGPFVARRKRDRLA
MLBr_00590|M.leprae_Br4923 AR-----IGVMLQG--GGGYPAARAGEMLNLVASYAADPLDPEWLLETLG
: * .
Mflv_2607|M.gilvum_PYR-GCK ATTLTELAKMGIDLPDVDVPIGSLSGGQKQCVAIARAVFFGARVLILDEP
Mvan_5292|M.vanbaalenii_PYR-1 REALTSLSVR--TVKSVRQPVSSLSGGQRQTVAIAKSVLWNSKVVLLDEP
MAB_2803c|M.abscessus_ATCC_199 LLEFVGLGDK------AKSYPDQLSGGQKQRVGIARALATSPSVLLADEA
MAV_0058|M.avium_104 QLDRVGLKHK------AGARPATLSGGQQQRVAIARALAMSPQVMFFDEA
Mb3784c|M.bovis_AF2122/97 VLERVGLDPKVATR-----YPAQLSGGEQQRVGVARALAADPPILLMDEP
Rv3758c|M.tuberculosis_H37Rv VLERVGLDPKVATR-----YPAQLSGGEQQRVGVARALAADPPILLMDEP
MMAR_0171|M.marinum_M LVEQFGLG-KYLNR-----KVGALSGGMRRRVDVALAVAHNPQMLFLDEP
MUL_4925|M.ulcerans_Agy99 LVEQFGLG-KYLNR-----KVGALSGGMRRRVDVALAVAHNPQMLFLDEP
TH_4070|M.thermoresistible__bu LLTAVGLPDPAARLR---SYPHQLSGGQRQRVMIAIALACDPEVLIADEP
MSMEG_3091|M.smegmatis_MC2_155 QAAIERVGGSFAPS----DVVANLSVADQQLTAIAKALTTDARVVIMDEP
MLBr_00590|M.leprae_Br4923 LTDVARTTYR------------RLSGGQQQRLALACTLVGRPELVFLDEP
** . :: :* :: . ::: **.
Mflv_2607|M.gilvum_PYR-GCK TAALGVKQSGVVLKYITAAKEAG-FGVVFITHNPHHAHLVGDHFVLLNRG
Mvan_5292|M.vanbaalenii_PYR-1 TAALGVAQTRQVIELVRGLAERG-VGVVLISHNMNDVFEVADRICALYLG
MAB_2803c|M.abscessus_ATCC_199 TSALDPETTSDVLRLLREVNAEFGVTIVVITHEMDVVRTVADHVAVLADG
MAV_0058|M.avium_104 TSALDPEMVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHG
Mb3784c|M.bovis_AF2122/97 FSAVDPVVRHELQNEILRLQAELHKTIVFVTHDIDEALKLADLVAVFAPG
Rv3758c|M.tuberculosis_H37Rv FSAVDPVVRHELQNEILRLQAELHKTIVFVTHDIDEALKLADLVAVFAPG
MMAR_0171|M.marinum_M SSGLDIEGKQEVWNAIRLLRSEG-RTVVLTTHDMDEAVSLADEVGIIKDG
MUL_4925|M.ulcerans_Agy99 SSGLDIEGKQEVWNAIRLLRSEG-RTVVLTTHDMDEAVLLADEVGIIKDG
TH_4070|M.thermoresistible__bu TTALDVTTQAQIIELVRELQRDFGTAVVWISHDLGVIGEVADEVTVLRHG
MSMEG_3091|M.smegmatis_MC2_155 SAALTDHDLAAVFRVIRELTSAG-KSVIYISHRLDEVKEIGDRATVMRDG
MLBr_00590|M.leprae_Br4923 TAGMDTHARLLVWELIDTLRRDG-VTVVLTTHQLKEAEELADRLVIIDHG
:.: : . : :: :* .* : *
Mflv_2607|M.gilvum_PYR-GCK RQKLDCSYDDITLEHLT---------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 RVAAEVKASEVSHGQVV---------------------------------
MAB_2803c|M.abscessus_ATCC_199 KVVETGTVFDVFSTPQS---------------------------------
MAV_0058|M.avium_104 KVVESGPPEQIFEAAET---------------------------------
Mb3784c|M.bovis_AF2122/97 GALAQYDETARLLSSPANDFVSKFIGLGRG--------------------
Rv3758c|M.tuberculosis_H37Rv GALAQYDETARLLSSPANDFVSKFIGLGRG--------------------
MMAR_0171|M.marinum_M -VLVAAGSTQEFTRSHG---------------------------------
MUL_4925|M.ulcerans_Agy99 -VLVAAGSTQEFTRSHG---------------------------------
TH_4070|M.thermoresistible__bu AAVEQAHIAEVFERPRHPYTRELLHARPRLGVGGPPQVTSTEVLLRVEGL
MSMEG_3091|M.smegmatis_MC2_155 ATVGVFDIASVTKDELVEAMIGRGLQALPP--------------------
MLBr_00590|M.leprae_Br4923 RMIAAGTPTELMHTGAK---------------------------------
Mflv_2607|M.gilvum_PYR-GCK -----------QQMAGGDELEALSHELRAAKQ------------------
Mvan_5292|M.vanbaalenii_PYR-1 -----------ELITAGRSGSLGLAPAQAAESM-----------------
MAB_2803c|M.abscessus_ATCC_199 -----------EAGKRFVGTVLRNTPSGEDIARIAQRHKGRIVAVEISEG
MAV_0058|M.avium_104 -----------ERLQRFLSQVL----------------------------
Mb3784c|M.bovis_AF2122/97 -YRWLQLFDAAGLPVRDIEQVSVNGLSDARDRQVRDGWVLVVDGAGAPLG
Rv3758c|M.tuberculosis_H37Rv -YRWLQLFDAAGLPVRDIEQVSVNGLSDARDRQVRDGWVLVVDGAGAPLG
MMAR_0171|M.marinum_M -------FAVDISAPQEITDDAVRQLAGAGYPMQRK-------GSSAVTG
MUL_4925|M.ulcerans_Agy99 -------FAVDISAPQEITDDAVRQLAGAGYPMQRK-------GSSAVTG
TH_4070|M.thermoresistible__bu QVRYDVSTPTGRSTVRAVSDLSLSIRRGTTLGLVGESGSGKSTVAAALTG
MSMEG_3091|M.smegmatis_MC2_155 ---RRSGPDGARTELLKVRRATIPGVLDVSDISVGRGEIVGLAGLGGAGR
MLBr_00590|M.leprae_Br4923 ------------DQLRFSAPPRLDLSLLAFALPEDYKTTELTPGEYLVAG
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 VQIGPALARATELGVRFEVVYGGITTLQSRSFGNLTLELEGPDDQVAHVV
MAV_0058|M.avium_104 --------------------------------------------------
Mb3784c|M.bovis_AF2122/97 WIDADGRRRHRGGAALSDAMTVGGSVFRPNGNLSQALDAALSSPSGVGVA
Rv3758c|M.tuberculosis_H37Rv WIDADGRRRHRGGAALSDAMTVGGSVFRPNGNLSQALDAALSSPSGVGVA
MMAR_0171|M.marinum_M SLDSASASEIGSLATVLDRLGLAGANIEIR---STSLRDAFLEATQ----
MUL_4925|M.ulcerans_Agy99 SLDSASASEIGSLATVLDRLGLAGANIEIR---STSLRDAFLEATQ----
TH_4070|M.thermoresistible__bu LVRPTAGRATLAGVDLFGVRGRDRRRLRRRISLVFQDPFSSLNPRMRVID
MSMEG_3091|M.smegmatis_MC2_155 STLLATLFGDRTATLDLTLNGVRLDRLTPRGAVAAGIGLVPEDRKSQGLF
MLBr_00590|M.leprae_Br4923 PIDPQVLATVTAWCAQINVLTTN-MRVEQHSLEDVFLDLTGRKLR-----
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 SDLSAVTTVQRVAR------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
Mb3784c|M.bovis_AF2122/97 VDGGGKVIGGILAADVLAEFQKGKKAGGGAKPCTT---------------
Rv3758c|M.tuberculosis_H37Rv VDGGGKVIGGILAADVLAEFQKGKKAGGGAKPCTT---------------
MMAR_0171|M.marinum_M --------------------------------------------------
MUL_4925|M.ulcerans_Agy99 --------------------------------------------------
TH_4070|M.thermoresistible__bu SISEPLRVHGLADGDRARCRRVADLLELVGLPADFG-------ARYPHEL
MSMEG_3091|M.smegmatis_MC2_155 LEQSILRNAGIAALRPLRVNPMKAAEQLCMPALRRLGVKFAGLDQPVGQL
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
Mb3784c|M.bovis_AF2122/97 --------------------------------------------------
Rv3758c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0171|M.marinum_M --------------------------------------------------
MUL_4925|M.ulcerans_Agy99 --------------------------------------------------
TH_4070|M.thermoresistible__bu SGGQRQRVSVARALATDPDLLILDESTASLDVSVQDRVLDLLADLQRELG
MSMEG_3091|M.smegmatis_MC2_155 SGGNQQKVVLAKWMARGIDLLLLDEPTRGLDIGAKGDLFEQVQALADSGV
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5292|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2803c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
Mb3784c|M.bovis_AF2122/97 --------------------------------------------------
Rv3758c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0171|M.marinum_M --------------------------------------------------
MUL_4925|M.ulcerans_Agy99 --------------------------------------------------
TH_4070|M.thermoresistible__bu LTYLFIAHDLAVVERMSHDVLVLRAGETVEYRPAAELFAAPEHEYTRALL
MSMEG_3091|M.smegmatis_MC2_155 GVLMASSELSELTENCDLIWVMHEGRNIAAFDPRTTSATDIARCVVTGRH
MLBr_00590|M.leprae_Br4923 --------------------------------------------------
Mflv_2607|M.gilvum_PYR-GCK ------------
Mvan_5292|M.vanbaalenii_PYR-1 ------------
MAB_2803c|M.abscessus_ATCC_199 ------------
MAV_0058|M.avium_104 ------------
Mb3784c|M.bovis_AF2122/97 ------------
Rv3758c|M.tuberculosis_H37Rv ------------
MMAR_0171|M.marinum_M ------------
MUL_4925|M.ulcerans_Agy99 ------------
TH_4070|M.thermoresistible__bu AAVPAVRPRAAG
MSMEG_3091|M.smegmatis_MC2_155 DND---------
MLBr_00590|M.leprae_Br4923 ------------