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M. smegmatis MC2 155 MSMEG_2951 (-)

annotation: 2Fe-2S-binding domain-containing protein
coordinates: 3011842 - 3012327
length: 161

MSDTVDISVEVDGDPAHLTVEADLTLLDVLREELGRTEVRAGCRNGDCGTCTAVVDGRCVKTCLILAARA
DGARVKTIATPSDGDRPDAVQRAFMEQYGFQCGFCLPGMLLAATDLLDRDPNPSAAAIRDALSGNLCRCT
GYTNAVRAVQRAAELRNQPPS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2951--100% (161)2Fe-2S-binding domain-containing protein
M. smegmatis MC2 155MSMEG_2464-7e-3446.75% (154) 2Fe-2S-binding domain-containing protein
M. smegmatis MC2 155MSMEG_0745-7e-3444.30% (149) 2Fe-2S-binding domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0381c-4e-3444.67% (150) carbon monoxyde dehydrogenase small subunit
M. gilvum PYR-GCKMflv_0282-9e-3545.18% (166) 2Fe-2S iron-sulfur cluster binding domain-containing protein
M. tuberculosis H37RvRv0374c-5e-3444.67% (150) carbon monoxyde dehydrogenase small subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-5e-2141.82% (110) xanthine dehydrogenase family protein
M. marinum MMMAR_0656coxS7e-3443.71% (151) carbon monoxyde dehydrogenase (small chain), CoxS
M. avium 104-----
M. thermoresistible (build 8)TH_0175-6e-3748.32% (149) PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN)
M. ulcerans Agy99MUL_0116coxS6e-3242.38% (151) carbon monoxyde dehydrogenase (small chain), CoxS
M. vanbaalenii PYR-1Mvan_5186-5e-3448.00% (150) 2Fe-2S iron-sulfur cluster binding domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_2951|M.smegmatis_MC2_155      MSD---TVDISVEVDGDPAHLTVEADLTLLDVLREELGRTEVRAGCRNGD
Mflv_0282|M.gilvum_PYR-GCK          MSQPLHTSHIDLTVDGDQRSLDVDNRLTLLDALREKLGATAPKKGCDHGQ
Mvan_5186|M.vanbaalenii_PYR-1       MHE----LPVEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTHLGCEHGA
Mb0381c|M.bovis_AF2122/97           -------MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSN
Rv0374c|M.tuberculosis_H37Rv        -------MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSN
MMAR_0656|M.marinum_M               ------MMQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSN
MUL_0116|M.ulcerans_Agy99           -------MQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSN
TH_0175|M.thermoresistible__bu      -------MQVSMTVNGEPVSAEVEPRLLLVHFLRDHLGLTGTHWGCDTSN
MAB_2925c|M.abscessus_ATCC_199      -----------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGD
                                               : *:*            *   **:.   .  : **  . 

MSMEG_2951|M.smegmatis_MC2_155      CGTCTAVVDGRCVKTCLILAARADGARVKTIATPSDGD-RPDAVQRAFME
Mflv_0282|M.gilvum_PYR-GCK          CGSCTVLVDGRRVTSCLTFAVAADGMRVTTAAGLGDAD-TLHPVAQAFQD
Mvan_5186|M.vanbaalenii_PYR-1       CGACTVLLDGQAVRSCLIFAVQVDGQEVTTVEGIAGEDGELSPVQAAMRE
Mb0381c|M.bovis_AF2122/97           CGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMR
Rv0374c|M.tuberculosis_H37Rv        CGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMR
MMAR_0656|M.marinum_M               CGTCVVDVDGVPVKSCTMLAVMASGRSIRTVEGLAAADGSLDPVQEGFMR
MUL_0116|M.ulcerans_Agy99           CGTCVVDVDGVPVKSCTMPAVMASGRSIRTVEGLAVADGSLDPVQEGFMR
TH_0175|M.thermoresistible__bu      CGTCVVEVDGYPVKSCTMLAAMASGRSVRTVEGLA-VDGALDPVQEGFMQ
MAB_2925c|M.abscessus_ATCC_199      CGACTVLVDGASQHSCIVPAHRVTDAEIHTVRSLAGEH-DLHPMQRGFID
                                    **:*.. :**    :*   *  . .  : *    .  .    .:  .:  

MSMEG_2951|M.smegmatis_MC2_155      QYGFQCGFCLPGMLLAAT---------------DLLDRDPNPSAAAIRDA
Mflv_0282|M.gilvum_PYR-GCK          EDAFQCGYCTPGQICSAVGMLDEVKSGAPSFVSDDLDAPPELTADEIRER
Mvan_5186|M.vanbaalenii_PYR-1       CHGLQCGFCTPGFVTSIT---------------ALLRDNPNPSDEEIREG
Mb0381c|M.bovis_AF2122/97           CHGLQCGFCTPGMLITAR---------------ALLDRNPDPDEQTIREA
Rv0374c|M.tuberculosis_H37Rv        CHGLQCGFCTPGMLITAR---------------ALLDRNPDPDEQTIREA
MMAR_0656|M.marinum_M               CHGLQCGFCTPGMMITAR---------------ALLDRNPDPDEETIREA
MUL_0116|M.ulcerans_Agy99           CHGLQCGFCTPGMMITAR---------------ALLDRNLDPDEETIREA
TH_0175|M.thermoresistible__bu      CHGLQCGFCTPGMMITAR---------------CLLDRDPDPDEDTIREA
MAB_2925c|M.abscessus_ATCC_199      HAGFQCGFCTAGMVLTAA-------------------TLTGDQTEDLGNA
                                      .:***:* .* : :                              : : 

MSMEG_2951|M.smegmatis_MC2_155      LSGNLCRCTGYTNAVRAVQRAAELRNQPPS--------------------
Mflv_0282|M.gilvum_PYR-GCK          MSGNLCRCAAYPNIVAAIGRAADR--------------------------
Mvan_5186|M.vanbaalenii_PYR-1       LSGNFCRCTGYQGIVNAVKRAAETTG------------------------
Mb0381c|M.bovis_AF2122/97           ISGQICRCTGYTTIVRSIQWAAAHQTVKAQS-------------------
Rv0374c|M.tuberculosis_H37Rv        ISGQICRCTGYTTIVRSIQWAAAHQTVKAQS-------------------
MMAR_0656|M.marinum_M               ISGQICRCTGYTTIVRSIQWAAKNAKEVASS-------------------
MUL_0116|M.ulcerans_Agy99           ISGQICRCTGYTTIVRSIQWAAKNAKEVASS-------------------
TH_0175|M.thermoresistible__bu      ISGQICRCTGYTTIVRSVQWAARRQRGEATPAPGVRTEATLGGDAAEPLL
MAB_2925c|M.abscessus_ATCC_199      LKGNLCRCTGYRPIRDAVCGVVPPRGSVSAPAAARVVTGTEPYTMDELPA
                                    :.*::***:.*     ::  ..                            

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      EAGSQS--------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      GVGHVAVLGSPHPSARITRIDTDRARLLPGVRAVLCYRDDPGVPFSTARH
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      HERTDDPDDTLVFDRVLRFAGQRVAAVVADTPAIAHRALEHIDVEYEVLP
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      AVFDPEMAQLPGAHLVHGDKGLGARIADPARNLVAEVHGEVGDVAAALAR
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      ARESGAVVTGSWQTARVQHVHLETHGSVGWQDERGRYVLRTSSQVPFLVR
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      DELCHVFGLAREQVRVFAPRVGGGFGAKQEMLTEDLVLLAVRVTGAPVVY
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      EFTRSDQFTIAPCRHPMRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSV
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      GVMFHGCNESMAQYRCANKRVDAQAVYTNNIPSGAFRGYGLGQVLFGIES
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      ALDELARNLGIDPFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLD
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      LAQDALARGAADPARNGSDLPAGWKVGEGMAIAMIATVPPRGHVADARAE
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      LDARGRYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVS
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      HDTGAFGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDG
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      VRAGADLLGLTEIAASAPEPLSAVGHHEGTPRSVAFNVQAFRVAVRPQTG
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      TVRILQSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALYEEILVHDGFVS
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_0282|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      TTALRNYHIPRLVDVPDTEVYFADTYDTFGPLGAKSMSESPYNPVAPALA
                                                                                      

MSMEG_2951|M.smegmatis_MC2_155      ----------------------------------
Mflv_0282|M.gilvum_PYR-GCK          ----------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       ----------------------------------
Mb0381c|M.bovis_AF2122/97           ----------------------------------
Rv0374c|M.tuberculosis_H37Rv        ----------------------------------
MMAR_0656|M.marinum_M               ----------------------------------
MUL_0116|M.ulcerans_Agy99           ----------------------------------
TH_0175|M.thermoresistible__bu      ----------------------------------
MAB_2925c|M.abscessus_ATCC_199      NAIRDAVGVRVYRLPMNAARVWRVINDSGGGESS