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QVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVDVDGVPVKSCTMPAVMASGRSI RTVEGLAVADGSLDPVQEGFMRCHGLQCGFCTPGMMITARALLDRNLDPDEETIREAISGQICRCTGYTT IVRSIQWAAKNAKEVASS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0116 | coxS | - | 100% (159) | carbon monoxyde dehydrogenase (small chain), CoxS |
| M. ulcerans Agy99 | MUL_4578 | coxS_1 | 4e-27 | 39.87% (153) | carbon monoxyde dehydrogenase (small chain), CoxS_1 |
| M. ulcerans Agy99 | MUL_0459 | - | 4e-23 | 37.93% (145) | carbon monoxide dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0381c | - | 2e-81 | 89.31% (159) | carbon monoxyde dehydrogenase small subunit |
| M. gilvum PYR-GCK | Mflv_1570 | - | 2e-38 | 47.65% (149) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0374c | - | 2e-81 | 89.31% (159) | carbon monoxyde dehydrogenase small subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 2e-22 | 40.58% (138) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_0656 | coxS | 2e-89 | 98.11% (159) | carbon monoxyde dehydrogenase (small chain), CoxS |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0745 | - | 2e-74 | 81.76% (159) | 2Fe-2S-binding domain-containing protein |
| M. thermoresistible (build 8) | TH_0175 | - | 1e-77 | 84.81% (158) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) |
| M. vanbaalenii PYR-1 | Mvan_5186 | - | 2e-40 | 49.01% (151) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1570|M.gilvum_PYR-GCK MHEIPVEVSVNGRRYAATVEPRLTLADYLREKCGLTGTHLGCEHGACGAC
Mvan_5186|M.vanbaalenii_PYR-1 MHELPVEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTHLGCEHGACGAC
MUL_0116|M.ulcerans_Agy99 ---MQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
MMAR_0656|M.marinum_M --MMQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
Mb0381c|M.bovis_AF2122/97 ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
Rv0374c|M.tuberculosis_H37Rv ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
TH_0175|M.thermoresistible__bu ---MQVSMTVNGEPVSAEVEPRLLLVHFLRDHLGLTGTHWGCDTSNCGTC
MSMEG_0745|M.smegmatis_MC2_155 ---MQVTMTVNGEAVTADVEPRMLLVHFLRDQLGLTGTHWGCDTSNCGTC
MAB_2925c|M.abscessus_ATCC_199 -------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGDCGAC
:.***. . .* * :**:: . .: **: . **:*
Mflv_1570|M.gilvum_PYR-GCK TALLDGQAVRACLVFAVQVDGQEVTTVEGIAGENGELSPVQAAMKECHGL
Mvan_5186|M.vanbaalenii_PYR-1 TVLLDGQAVRSCLIFAVQVDGQEVTTVEGIAGEDGELSPVQAAMRECHGL
MUL_0116|M.ulcerans_Agy99 VVDVDGVPVKSCTMPAVMASGRSIRTVEGLAVADGSLDPVQEGFMRCHGL
MMAR_0656|M.marinum_M VVDVDGVPVKSCTMLAVMASGRSIRTVEGLAAADGSLDPVQEGFMRCHGL
Mb0381c|M.bovis_AF2122/97 VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
Rv0374c|M.tuberculosis_H37Rv VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
TH_0175|M.thermoresistible__bu VVEVDGYPVKSCTMLAAMASGRSVRTVEGLA-VDGALDPVQEGFMQCHGL
MSMEG_0745|M.smegmatis_MC2_155 VVEVDGEPVKSCTMLAAMASGHSVNTVEGME-VDGKLDPVQEGFMQCHGL
MAB_2925c|M.abscessus_ATCC_199 TVLVDGASQHSCIVPAHRVTDAEIHTVRSLAGEHD-LHPMQRGFIDHAGF
.. :** . ::* : * . . .: **..: .. * *:* .: *:
Mflv_1570|M.gilvum_PYR-GCK QCGFCTPGFVTSITALLRDNPAPTDTEIREGLSGNFCRCTGYQGIVNAVK
Mvan_5186|M.vanbaalenii_PYR-1 QCGFCTPGFVTSITALLRDNPNPSDEEIREGLSGNFCRCTGYQGIVNAVK
MUL_0116|M.ulcerans_Agy99 QCGFCTPGMMITARALLDRNLDPDEETIREAISGQICRCTGYTTIVRSIQ
MMAR_0656|M.marinum_M QCGFCTPGMMITARALLDRNPDPDEETIREAISGQICRCTGYTTIVRSIQ
Mb0381c|M.bovis_AF2122/97 QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
Rv0374c|M.tuberculosis_H37Rv QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
TH_0175|M.thermoresistible__bu QCGFCTPGMMITARCLLDRDPDPDEDTIREAISGQICRCTGYTTIVRSVQ
MSMEG_0745|M.smegmatis_MC2_155 QCGFCTPGMMITARALLRQNPDPTEEEIREAISGQICRCTGYTTIVRSVQ
MAB_2925c|M.abscessus_ATCC_199 QCGFCTAGMVLTAATLTGDQT----EDLGNALKGNLCRCTGYRPIRDAVC
******.*:: : * : : :.:.*::****** * ::
Mflv_1570|M.gilvum_PYR-GCK RAAETTG-------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 RAAETTG-------------------------------------------
MUL_0116|M.ulcerans_Agy99 WAAKNAKEVASS--------------------------------------
MMAR_0656|M.marinum_M WAAKNAKEVASS--------------------------------------
Mb0381c|M.bovis_AF2122/97 WAAAHQTVKAQS--------------------------------------
Rv0374c|M.tuberculosis_H37Rv WAAAHQTVKAQS--------------------------------------
TH_0175|M.thermoresistible__bu WAARRQRGEATPAPGVRTEATLGGDAAEPLLEAGSQS-------------
MSMEG_0745|M.smegmatis_MC2_155 WAARHAREEAKA--------------------------------------
MAB_2925c|M.abscessus_ATCC_199 GVVPPRGSVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITR
..
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 IDTDRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRF
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 AGQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGD
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 KGLGARIADPARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQH
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAP
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RVGGGFGAKQEMLTEDLVLLAVRVTGAPVVYEFTRSDQFTIAPCRHPMRV
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANK
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RVDAQAVYTNNIPSGAFRGYGLGQVLFGIESALDELARNLGIDPFEFRRR
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPARNGSD
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 LPAGWKVGEGMAIAMIATVPPRGHVADARAELDARGRYRISVGSAEFGNG
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 TTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAFGSAGTTVAGLAVY
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGADLLGLTEIAASAPE
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 PLSAVGHHEGTPRSVAFNVQAFRVAVRPQTGTVRILQSVQTADAGVVVNP
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QQCRGQVEGGVAQAIGSALYEEILVHDGFVSTTALRNYHIPRLVDVPDTE
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
MMAR_0656|M.marinum_M --------------------------------------------------
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
TH_0175|M.thermoresistible__bu --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VYFADTYDTFGPLGAKSMSESPYNPVAPALANAIRDAVGVRVYRLPMNAA
Mflv_1570|M.gilvum_PYR-GCK ---------------
Mvan_5186|M.vanbaalenii_PYR-1 ---------------
MUL_0116|M.ulcerans_Agy99 ---------------
MMAR_0656|M.marinum_M ---------------
Mb0381c|M.bovis_AF2122/97 ---------------
Rv0374c|M.tuberculosis_H37Rv ---------------
TH_0175|M.thermoresistible__bu ---------------
MSMEG_0745|M.smegmatis_MC2_155 ---------------
MAB_2925c|M.abscessus_ATCC_199 RVWRVINDSGGGESS