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MHTVEMSGATSGQGVEVSVIVNGRLVERTVPARLTLADFLRDELQLTGTHLGCEHGVCGACSVFVDGRGV RACLMLAVQADGTRVTTVEGLDEFEETQRLRQAFSARGGLQCGFCTPGFLVSAVELLRDPDTEKPLTEDS VREALSGNICRCTGYQGIVQAVLDAADG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2464 | - | - | 100% (168) | 2Fe-2S-binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_5883 | - | 9e-43 | 55.92% (152) | 2Fe-2S-binding domain-containing protein |
| M. smegmatis MC2 155 | MSMEG_0745 | - | 1e-35 | 49.02% (153) | 2Fe-2S-binding domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0381c | - | 3e-34 | 48.70% (154) | carbon monoxyde dehydrogenase small subunit |
| M. gilvum PYR-GCK | Mflv_1570 | - | 1e-44 | 57.79% (154) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
| M. tuberculosis H37Rv | Rv0374c | - | 3e-34 | 48.70% (154) | carbon monoxyde dehydrogenase small subunit |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2925c | - | 6e-20 | 36.62% (142) | xanthine dehydrogenase family protein |
| M. marinum M | MMAR_0621 | coxS_3 | 3e-43 | 57.52% (153) | carbon monoxyde dehydrogenase (small chain), CoxS_3 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_1272 | - | 4e-44 | 55.19% (154) | PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) |
| M. ulcerans Agy99 | MUL_0116 | coxS | 7e-33 | 46.79% (156) | carbon monoxyde dehydrogenase (small chain), CoxS |
| M. vanbaalenii PYR-1 | Mvan_5186 | - | 1e-43 | 57.24% (152) | 2Fe-2S iron-sulfur cluster binding domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0381c|M.bovis_AF2122/97 --------------MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTH
Rv0374c|M.tuberculosis_H37Rv --------------MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTH
MUL_0116|M.ulcerans_Agy99 --------------MQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTH
Mflv_1570|M.gilvum_PYR-GCK MH-----------EIPVEVSVNGRRYAATVEPRLTLADYLREKCGLTGTH
Mvan_5186|M.vanbaalenii_PYR-1 MH-----------ELPVEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTH
MMAR_0621|M.marinum_M MH-----------ERSVQLSVNGNHVAARVEPRMTLADFLRERCGLTGTH
TH_1272|M.thermoresistible__bu VH-----------DHQVELTVNGQRTSAPVESRLTLADFLRERCGLTGTH
MSMEG_2464|M.smegmatis_MC2_155 MHTVEMSGATSGQGVEVSVIVNGRLVERTVPARLTLADFLRDELQLTGTH
MAB_2925c|M.abscessus_ATCC_199 ------------------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVK
: ***. . * :**:. . .:
Mb0381c|M.bovis_AF2122/97 WGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDP
Rv0374c|M.tuberculosis_H37Rv WGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDP
MUL_0116|M.ulcerans_Agy99 WGCDTSNCGTCVVDVDGVPVKSCTMPAVMASGRSIRTVEGLAVADGSLDP
Mflv_1570|M.gilvum_PYR-GCK LGCEHGACGACTALLDGQAVRACLVFAVQVDGQEVTTVEGIAGENGELSP
Mvan_5186|M.vanbaalenii_PYR-1 LGCEHGACGACTVLLDGQAVRSCLIFAVQVDGQEVTTVEGIAGEDGELSP
MMAR_0621|M.marinum_M LGCEHGACGACTVLVGGDAVRSCLLFAVQADGAEVTTVEGIASADGELSP
TH_1272|M.thermoresistible__bu LGCEHGACGACTVIMDGAAVRSCLVFAVQADGSEVTTVEGIASPDGELSP
MSMEG_2464|M.smegmatis_MC2_155 LGCEHGVCGACSVFVDGRGVRACLMLAVQADGTRVTTVEGLD-EFEETQR
MAB_2925c|M.abscessus_ATCC_199 KGCDAGDCGACTVLVDGASQHSCIVPAHRVTDAEIHTVRSLAGEHD-LHP
**: . **:* . :.* ::* : * . . : **..:
Mb0381c|M.bovis_AF2122/97 VQEGFMRCHGLQCGFCTPGMLITARALLDR---NPDPDEQTIREAISGQI
Rv0374c|M.tuberculosis_H37Rv VQEGFMRCHGLQCGFCTPGMLITARALLDR---NPDPDEQTIREAISGQI
MUL_0116|M.ulcerans_Agy99 VQEGFMRCHGLQCGFCTPGMMITARALLDR---NLDPDEETIREAISGQI
Mflv_1570|M.gilvum_PYR-GCK VQAAMKECHGLQCGFCTPGFVTSITALLRD---NPAPTDTEIREGLSGNF
Mvan_5186|M.vanbaalenii_PYR-1 VQAAMRECHGLQCGFCTPGFVTSITALLRD---NPNPSDEEIREGLSGNF
MMAR_0621|M.marinum_M VQSALRECHGLQCGFCTPGFVVSITALLRD---NPDPTDEQIREGLSGNF
TH_1272|M.thermoresistible__bu VQQAMRDCHGLQCGFCTPGFVTTITAMLQE---NPDPTDEEIREGLSGNF
MSMEG_2464|M.smegmatis_MC2_155 LRQAFSARGGLQCGFCTPGFLVSAVELLRDPDTEKPLTEDSVREALSGNI
MAB_2925c|M.abscessus_ATCC_199 MQRGFIDHAGFQCGFCTAGMVLTAATLTGD-------QTEDLGNALKGNL
:: .: *:******.*:: : : : :.:.*::
Mb0381c|M.bovis_AF2122/97 CRCTGYTTIVRSIQWAAAHQTVKAQS------------------------
Rv0374c|M.tuberculosis_H37Rv CRCTGYTTIVRSIQWAAAHQTVKAQS------------------------
MUL_0116|M.ulcerans_Agy99 CRCTGYTTIVRSIQWAAKNAKEVASS------------------------
Mflv_1570|M.gilvum_PYR-GCK CRCTGYQGIVNAVKRAAETTG-----------------------------
Mvan_5186|M.vanbaalenii_PYR-1 CRCTGYQGIVNAVKRAAETTG-----------------------------
MMAR_0621|M.marinum_M CRCTGYQGIVAATRRASELMSQ----------------------------
TH_1272|M.thermoresistible__bu CRCTGYQGIIKAVRQAAEAMRA----------------------------
MSMEG_2464|M.smegmatis_MC2_155 CRCTGYQGIVQAVLDAADG-------------------------------
MAB_2925c|M.abscessus_ATCC_199 CRCTGYRPIRDAVCGVVPPRGSVSAPAAARVVTGTEPYTMDELPAGVGHV
****** * : .
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 AVLGSPHPSARITRIDTDRARLLPGVRAVLCYRDDPGVPFSTARHHERTD
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 DPDDTLVFDRVLRFAGQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDP
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 EMAQLPGAHLVHGDKGLGARIADPARNLVAEVHGEVGDVAAALARARESG
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 AVVTGSWQTARVQHVHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCH
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 VFGLAREQVRVFAPRVGGGFGAKQEMLTEDLVLLAVRVTGAPVVYEFTRS
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 DQFTIAPCRHPMRVNVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFH
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 GCNESMAQYRCANKRVDAQAVYTNNIPSGAFRGYGLGQVLFGIESALDEL
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 ARNLGIDPFEFRRRNVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDA
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 LARGAADPARNGSDLPAGWKVGEGMAIAMIATVPPRGHVADARAELDARG
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 RYRISVGSAEFGNGTTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGA
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 FGSAGTTVAGLAVYRAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGA
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 DLLGLTEIAASAPEPLSAVGHHEGTPRSVAFNVQAFRVAVRPQTGTVRIL
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 QSVQTADAGVVVNPQQCRGQVEGGVAQAIGSALYEEILVHDGFVSTTALR
Mb0381c|M.bovis_AF2122/97 --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0116|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1570|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0621|M.marinum_M --------------------------------------------------
TH_1272|M.thermoresistible__bu --------------------------------------------------
MSMEG_2464|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199 NYHIPRLVDVPDTEVYFADTYDTFGPLGAKSMSESPYNPVAPALANAIRD
Mb0381c|M.bovis_AF2122/97 -----------------------------
Rv0374c|M.tuberculosis_H37Rv -----------------------------
MUL_0116|M.ulcerans_Agy99 -----------------------------
Mflv_1570|M.gilvum_PYR-GCK -----------------------------
Mvan_5186|M.vanbaalenii_PYR-1 -----------------------------
MMAR_0621|M.marinum_M -----------------------------
TH_1272|M.thermoresistible__bu -----------------------------
MSMEG_2464|M.smegmatis_MC2_155 -----------------------------
MAB_2925c|M.abscessus_ATCC_199 AVGVRVYRLPMNAARVWRVINDSGGGESS