For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb0381c (-)

annotation: carbon monoxyde dehydrogenase small subunit
coordinates: 452817 - 453296
length: 159

MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTCVVEVDGVPVKSCTMLAVMASGHS
IRTVEGLAGPDGQLDPVQEGFMRCHGLQCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYT
TIVRSIQWAAAHQTVKAQS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0381c--100% (159)carbon monoxyde dehydrogenase small subunit

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1570-5e-4149.32% (148) 2Fe-2S iron-sulfur cluster binding domain-containing protein
M. tuberculosis H37RvRv0374c-3e-93100.00% (159) carbon monoxyde dehydrogenase small subunit
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2925c-1e-2141.01% (139) xanthine dehydrogenase family protein
M. marinum MMMAR_0656coxS1e-8390.57% (159) carbon monoxyde dehydrogenase (small chain), CoxS
M. avium 104-----
M. smegmatis MC2 155MSMEG_0745-5e-7682.39% (159) 2Fe-2S-binding domain-containing protein
M. thermoresistible (build 8)TH_0175-1e-7785.35% (157) PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN)
M. ulcerans Agy99MUL_0116coxS2e-8189.31% (159) carbon monoxyde dehydrogenase (small chain), CoxS
M. vanbaalenii PYR-1Mvan_5186-1e-4250.00% (150) 2Fe-2S iron-sulfur cluster binding domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_1570|M.gilvum_PYR-GCK          MHEIPVEVSVNGRRYAATVEPRLTLADYLREKCGLTGTHLGCEHGACGAC
Mvan_5186|M.vanbaalenii_PYR-1       MHELPVEVSVNGRRYAGTVEPRVTLADYLRERCGLTGTHLGCEHGACGAC
Mb0381c|M.bovis_AF2122/97           ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
Rv0374c|M.tuberculosis_H37Rv        ---MQVNMTVNGEPVTAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
MMAR_0656|M.marinum_M               --MMQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
MUL_0116|M.ulcerans_Agy99           ---MQVNMTVNGEPVSAEVEPRMLLVHFLRDQLRLTGTHWGCDTSNCGTC
TH_0175|M.thermoresistible__bu      ---MQVSMTVNGEPVSAEVEPRLLLVHFLRDHLGLTGTHWGCDTSNCGTC
MSMEG_0745|M.smegmatis_MC2_155      ---MQVTMTVNGEAVTADVEPRMLLVHFLRDQLGLTGTHWGCDTSNCGTC
MAB_2925c|M.abscessus_ATCC_199      -------MKVNGKLIDASPRPGQCLRTFLREHG-HVEVKKGCDAGDCGAC
                                           :.***.   .  .*   *  :**::   . .: **: . **:*

Mflv_1570|M.gilvum_PYR-GCK          TALLDGQAVRACLVFAVQVDGQEVTTVEGIAGENGELSPVQAAMKECHGL
Mvan_5186|M.vanbaalenii_PYR-1       TVLLDGQAVRSCLIFAVQVDGQEVTTVEGIAGEDGELSPVQAAMRECHGL
Mb0381c|M.bovis_AF2122/97           VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
Rv0374c|M.tuberculosis_H37Rv        VVEVDGVPVKSCTMLAVMASGHSIRTVEGLAGPDGQLDPVQEGFMRCHGL
MMAR_0656|M.marinum_M               VVDVDGVPVKSCTMLAVMASGRSIRTVEGLAAADGSLDPVQEGFMRCHGL
MUL_0116|M.ulcerans_Agy99           VVDVDGVPVKSCTMPAVMASGRSIRTVEGLAVADGSLDPVQEGFMRCHGL
TH_0175|M.thermoresistible__bu      VVEVDGYPVKSCTMLAAMASGRSVRTVEGLA-VDGALDPVQEGFMQCHGL
MSMEG_0745|M.smegmatis_MC2_155      VVEVDGEPVKSCTMLAAMASGHSVNTVEGME-VDGKLDPVQEGFMQCHGL
MAB_2925c|M.abscessus_ATCC_199      TVLVDGASQHSCIVPAHRVTDAEIHTVRSLAGEHD-LHPMQRGFIDHAGF
                                    .. :** . ::* : *  . . .: **..:   .. * *:* .:    *:

Mflv_1570|M.gilvum_PYR-GCK          QCGFCTPGFVTSITALLRDNPAPTDTEIREGLSGNFCRCTGYQGIVNAVK
Mvan_5186|M.vanbaalenii_PYR-1       QCGFCTPGFVTSITALLRDNPNPSDEEIREGLSGNFCRCTGYQGIVNAVK
Mb0381c|M.bovis_AF2122/97           QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
Rv0374c|M.tuberculosis_H37Rv        QCGFCTPGMLITARALLDRNPDPDEQTIREAISGQICRCTGYTTIVRSIQ
MMAR_0656|M.marinum_M               QCGFCTPGMMITARALLDRNPDPDEETIREAISGQICRCTGYTTIVRSIQ
MUL_0116|M.ulcerans_Agy99           QCGFCTPGMMITARALLDRNLDPDEETIREAISGQICRCTGYTTIVRSIQ
TH_0175|M.thermoresistible__bu      QCGFCTPGMMITARCLLDRDPDPDEDTIREAISGQICRCTGYTTIVRSVQ
MSMEG_0745|M.smegmatis_MC2_155      QCGFCTPGMMITARALLRQNPDPTEEEIREAISGQICRCTGYTTIVRSVQ
MAB_2925c|M.abscessus_ATCC_199      QCGFCTAGMVLTAATLTGDQT----EDLGNALKGNLCRCTGYRPIRDAVC
                                    ******.*:: :   *   :       : :.:.*::******  *  :: 

Mflv_1570|M.gilvum_PYR-GCK          RAAETTG-------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       RAAETTG-------------------------------------------
Mb0381c|M.bovis_AF2122/97           WAAAHQTVKAQS--------------------------------------
Rv0374c|M.tuberculosis_H37Rv        WAAAHQTVKAQS--------------------------------------
MMAR_0656|M.marinum_M               WAAKNAKEVASS--------------------------------------
MUL_0116|M.ulcerans_Agy99           WAAKNAKEVASS--------------------------------------
TH_0175|M.thermoresistible__bu      WAARRQRGEATPAPGVRTEATLGGDAAEPLLEAGSQS-------------
MSMEG_0745|M.smegmatis_MC2_155      WAARHAREEAKA--------------------------------------
MAB_2925c|M.abscessus_ATCC_199      GVVPPRGSVSAPAAARVVTGTEPYTMDELPAGVGHVAVLGSPHPSARITR
                                     ..                                               

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      IDTDRARLLPGVRAVLCYRDDPGVPFSTARHHERTDDPDDTLVFDRVLRF
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      AGQRVAAVVADTPAIAHRALEHIDVEYEVLPAVFDPEMAQLPGAHLVHGD
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      KGLGARIADPARNLVAEVHGEVGDVAAALARARESGAVVTGSWQTARVQH
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      VHLETHGSVGWQDERGRYVLRTSSQVPFLVRDELCHVFGLAREQVRVFAP
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      RVGGGFGAKQEMLTEDLVLLAVRVTGAPVVYEFTRSDQFTIAPCRHPMRV
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      NVTAAADGDGVLTALAVDVLSDAGAYGNHSVGVMFHGCNESMAQYRCANK
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      RVDAQAVYTNNIPSGAFRGYGLGQVLFGIESALDELARNLGIDPFEFRRR
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      NVIVPGDSFVSWEVEEDDLAFGSYGLDQCLDLAQDALARGAADPARNGSD
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      LPAGWKVGEGMAIAMIATVPPRGHVADARAELDARGRYRISVGSAEFGNG
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      TTTVHAQLAAGVLGCAPDQVYIHQADTDAVSHDTGAFGSAGTTVAGLAVY
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      RAAELLRDQIIRFAATKLAVPQSRCVLEPDGVRAGADLLGLTEIAASAPE
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      PLSAVGHHEGTPRSVAFNVQAFRVAVRPQTGTVRILQSVQTADAGVVVNP
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      QQCRGQVEGGVAQAIGSALYEEILVHDGFVSTTALRNYHIPRLVDVPDTE
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5186|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb0381c|M.bovis_AF2122/97           --------------------------------------------------
Rv0374c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_0656|M.marinum_M               --------------------------------------------------
MUL_0116|M.ulcerans_Agy99           --------------------------------------------------
TH_0175|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0745|M.smegmatis_MC2_155      --------------------------------------------------
MAB_2925c|M.abscessus_ATCC_199      VYFADTYDTFGPLGAKSMSESPYNPVAPALANAIRDAVGVRVYRLPMNAA
                                                                                      

Mflv_1570|M.gilvum_PYR-GCK          ---------------
Mvan_5186|M.vanbaalenii_PYR-1       ---------------
Mb0381c|M.bovis_AF2122/97           ---------------
Rv0374c|M.tuberculosis_H37Rv        ---------------
MMAR_0656|M.marinum_M               ---------------
MUL_0116|M.ulcerans_Agy99           ---------------
TH_0175|M.thermoresistible__bu      ---------------
MSMEG_0745|M.smegmatis_MC2_155      ---------------
MAB_2925c|M.abscessus_ATCC_199      RVWRVINDSGGGESS