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LKSVGIPKGTECCPDAFQWDRREDCEVRQILDRIADKWSLLIIALLDDGSMRFTELKRMIDGISQRMLTV TLRQLERDGLVRRTVHPVVPPRVDYELTDLGRTLHQTVQPLVRWTEEHQRDIAAARQRFDEAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2849 | - | - | 100% (133) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_5162 | - | 2e-21 | 49.47% (95) | cinnamoyl ester hydrolase |
| M. smegmatis MC2 155 | MSMEG_6344 | - | 4e-17 | 42.31% (104) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1754c | - | 6e-09 | 33.70% (92) | hypothetical protein Mb1754c |
| M. gilvum PYR-GCK | Mflv_5238 | - | 4e-14 | 40.62% (96) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1725c | - | 6e-09 | 33.70% (92) | hypothetical protein Rv1725c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3696c | - | 7e-25 | 46.23% (106) | putative transcriptional regulator |
| M. marinum M | MMAR_1555 | - | 1e-08 | 32.65% (98) | transcriptional regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_2405 | - | 2e-11 | 36.96% (92) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3475 | - | 8e-09 | 32.65% (98) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1032 | - | 2e-13 | 37.50% (96) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1555|M.marinum_M ------------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGV
MUL_3475|M.ulcerans_Agy99 ------------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGV
Mb1754c|M.bovis_AF2122/97 -----------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGP
Rv1725c|M.tuberculosis_H37Rv -----------------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGP
Mflv_5238|M.gilvum_PYR-GCK ---------MGRLADVSRRTYGQYCGLAHALDVVGERWTLLIVRELASGP
Mvan_1032|M.vanbaalenii_PYR-1 ---------MSTIVGMTRRSYGQFCGLAHALDVVGERWTLLIVRELGSGP
TH_2405|M.thermoresistible__bu ---------------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGP
MSMEG_2849|M.smegmatis_MC2_155 MKSVGIPKGTECCPDAFQWDRREDCEVRQILDRIADKWSLLIIALLDDGS
MAB_3696c|M.abscessus_ATCC_199 MYPSSQPT-DDWWGNLFDT----QCPTRIVLDRIGDKWTVLVVAALADGP
: :.::*::*:: *
MMAR_1555|M.marinum_M QRFGQLARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQDP-ERHEYRLTD
MUL_3475|M.ulcerans_Agy99 QRFGQLARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQDP-ERHEYRLTD
Mb1754c|M.bovis_AF2122/97 LRFTEIERGLPGISRSVLAQRLRRLQHDRIIEAVPEHTG----GGYRFTV
Rv1725c|M.tuberculosis_H37Rv LRFTEIERGLPGISRSVLAQRLRRLQHDRIIEAVPEHTG----GGYRFTV
Mflv_5238|M.gilvum_PYR-GCK KRYTELADALAGIGTSLLATRVRQLETDGVVQRRLALDQPGSTVVYELSD
Mvan_1032|M.vanbaalenii_PYR-1 KRYGELADALAGIGTSLLATRMRQLETDGVIQRRLDLDQPGSAVVYELSD
TH_2405|M.thermoresistible__bu RRYSDLLTALRPIATDMLATRLRHLEEHHLVRRR-ELPKPASGTVYELTA
MSMEG_2849|M.smegmatis_MC2_155 MRFTELKRMIDGISQRMLTVTLRQLERDGLVRRTVHPVVP-PRVDYELTD
MAB_3696c|M.abscessus_ATCC_199 MRFTALRDRIGGVTGKVLTSTLRSMLRDGLVKRTAYATVP-PKVEYQLTE
*: : : : *: :* : :: *.::
MMAR_1555|M.marinum_M TGHELFAAIVVLMQWGDKHLP---------------------NPDGPP--
MUL_3475|M.ulcerans_Agy99 TGHELFAAIVVLMQWGDKHLP---------------------NPDGPP--
Mb1754c|M.bovis_AF2122/97 AGEELRPVLQTLGDWVSRWLMADPTPAECDPELLTLWISRRVNTEALPGR
Rv1725c|M.tuberculosis_H37Rv AGEELRPVLQTLGDWVSRWLMADPTPAECDPELLTLWISRRVNTEALPGR
Mflv_5238|M.gilvum_PYR-GCK AGRELAAAVVPLAMWGARHQMADADVCHEAFRAEWLLSFLAADVRRDGPH
Mvan_1032|M.vanbaalenii_PYR-1 AGRELAEAMIPLAMWGARHQMSHADPCAEAFRAEWLLAFLAADLRGGIPE
TH_2405|M.thermoresistible__bu DGAALEAVVHAFIRWGR--SLLETRRAGDVVRPHWLARAVRAHVR---PD
MSMEG_2849|M.smegmatis_MC2_155 LGRTLHQTVQPLVRWTEEHQR-----------------------------
MAB_3696c|M.abscessus_ATCC_199 LGLSLREPIDQLRTWAERNVA-----------------------------
* * : : *
MMAR_1555|M.marinum_M ---IVLRHHCG------QFVEP-----------------------RLICA
MUL_3475|M.ulcerans_Agy99 ---IVLRHHCG------QFVEP-----------------------RLICA
Mb1754c|M.bovis_AF2122/97 RVVVEFRYHGERPLWAWLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRV
Rv1725c|M.tuberculosis_H37Rv RVVVEFRYHGERPLWAWLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRV
Mflv_5238|M.gilvum_PYR-GCK DLDAVYEFHIDDS-TACLRLRDGGVTVTPGAPATPGDVVVRSRASTIAEI
Mvan_1032|M.vanbaalenii_PYR-1 GLASVYEFHVDDS-TACLQIRDGRVSVRPGPCATPADVTVRATARAIAAV
TH_2405|M.thermoresistible__bu RTGPPLSVRLVTP-EGAAAVRISADAVEDLDDDTAVDVTLTGAAEVLAAA
MSMEG_2849|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3696c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1555|M.marinum_M HCG-----EEITARNVTPEAGPGFG-----------------DAVAAPN-
MUL_3475|M.ulcerans_Agy99 HCG-----EEITARNVTPEAGPGYG-----------------DAVAAPN-
Mb1754c|M.bovis_AF2122/97 YSGRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQ
Rv1725c|M.tuberculosis_H37Rv YSGRSTLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQ
Mflv_5238|M.gilvum_PYR-GCK VGHKIAVADALADGSLEITGDADKIS-------------ALVGVIEKRLA
Mvan_1032|M.vanbaalenii_PYR-1 VGQKDRLEDAVAEGRIEVTGDPAAIA-------------TLIGAVEKRLA
TH_2405|M.thermoresistible__bu L-HPDRAAELVAQGRLRVDGRADALR-------------RLAEVVTAPAG
MSMEG_2849|M.smegmatis_MC2_155 ---------DIAAARQRFDEAN----------------------------
MAB_3696c|M.abscessus_ATCC_199 ---------HIVRNREAHDGDMPSTD----------------TAIG----
:
MMAR_1555|M.marinum_M -------
MUL_3475|M.ulcerans_Agy99 -------
Mb1754c|M.bovis_AF2122/97 MPEAHGG
Rv1725c|M.tuberculosis_H37Rv MPEAHGG
Mflv_5238|M.gilvum_PYR-GCK R------
Mvan_1032|M.vanbaalenii_PYR-1 -------
TH_2405|M.thermoresistible__bu RAVPDRS
MSMEG_2849|M.smegmatis_MC2_155 -------
MAB_3696c|M.abscessus_ATCC_199 -------