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VQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTEIERGLPGISRSVLAQRLRRLQHDRIIEAVPEH TGGGYRFTVAGEELRPVLQTLGDWVSRWLMADPTPAECDPELLTLWISRRVNTEALPGRRVVVEFRYHGE RPLWAWLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRVYSGRSTLAAEISAERIELDGLPAMRRAFPSW MAWSPFAPAMRQAVVSVDQMPEAHGG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1754c | - | - | 100% (236) | hypothetical protein Mb1754c |
M. bovis AF2122 / 97 | Mb3122 | - | 1e-11 | 41.94% (93) | putative transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5238 | - | 1e-19 | 31.68% (202) | HxlR family transcriptional regulator |
M. tuberculosis H37Rv | Rv1725c | - | 1e-140 | 100.00% (236) | hypothetical protein Rv1725c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_3456 | - | 5e-12 | 35.24% (105) | HxlR family transcriptional regulator |
M. marinum M | MMAR_1626 | - | 1e-33 | 36.04% (222) | transcriptional regulator |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_5032 | - | 1e-14 | 41.18% (102) | putative transcriptional regulator |
M. thermoresistible (build 8) | TH_2405 | - | 6e-15 | 31.31% (214) | putative transcriptional regulator |
M. ulcerans Agy99 | MUL_3410 | - | 6e-34 | 36.04% (222) | transcriptional regulator |
M. vanbaalenii PYR-1 | Mvan_1032 | - | 4e-21 | 34.15% (205) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_5032|M.smegmatis_MC2_155 ------MASRSYGQYCALAKSLDLVGDRWTLLVVRELLDGPRRYGDLLSA TH_2405|M.thermoresistible__bu ------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGPRRYSDLLTA Mflv_5238|M.gilvum_PYR-GCK MGRLADVSRRTYGQYCGLAHALDVVGERWTLLIVRELASGPKRYTELADA Mvan_1032|M.vanbaalenii_PYR-1 MSTIVGMTRRSYGQFCGLAHALDVVGERWTLLIVRELGSGPKRYGELADA Mb1754c|M.bovis_AF2122/97 --------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTEIERG Rv1725c|M.tuberculosis_H37Rv --------MQPYGQYCPVARAAELLGDRWTLLIVRELLFGPLRFTEIERG MMAR_1626|M.marinum_M --------MSTYSQFCPVAKAMELLDERWTLLVVRELLLGSTHFNDLRRG MUL_3410|M.ulcerans_Agy99 --------MSTYSQFCPVAKAMELLDERWTLLVVRELLLGSTHFNDLRRG MAB_3456|M.abscessus_ATCC_1997 -------MDFTTMRNCSISNALDVIGERWTLVALREIMLGNRRFETIVRN . : * ::.: :::.:****: :**: * :: : MSMEG_5032|M.smegmatis_MC2_155 LSPIATDVLAGRLRDLEANNLVHKR-AMPRPSATTVYALTADGRALEDVI TH_2405|M.thermoresistible__bu LRPIATDMLATRLRHLEEHHLVRRR-ELPKPASGTVYELTADGAALEAVV Mflv_5238|M.gilvum_PYR-GCK LAGIGTSLLATRVRQLETDGVVQRRLALDQPGSTVVYELSDAGRELAAAV Mvan_1032|M.vanbaalenii_PYR-1 LAGIGTSLLATRMRQLETDGVIQRRLDLDQPGSAVVYELSDAGRELAEAM Mb1754c|M.bovis_AF2122/97 LPGISRSVLAQRLRRLQHDRIIEAV----PEHTGGGYRFTVAGEELRPVL Rv1725c|M.tuberculosis_H37Rv LPGISRSVLAQRLRRLQHDRIIEAV----PEHTGGGYRFTVAGEELRPVL MMAR_1626|M.marinum_M VPKMSPALLSKRLKSLTKAGVVERS----DIEGRTSYSLTTCGRELATVV MUL_3410|M.ulcerans_Agy99 VPKMSPALLSKRLKSLTKAAVVERS----DIEGRTSYSLTTCGRELATVV MAB_3456|M.abscessus_ATCC_1997 TG-ASRDILATRLRKLVDAGVLEKR-RYEDRPPRYEYLLTQSGQALRPVL . :*: *:: * ::. * :: * * .: MSMEG_5032|M.smegmatis_MC2_155 NAFARWGR--HLLANRDRKETVRPEWLVRAVRAYVRDD-RTGPPVTVRMV TH_2405|M.thermoresistible__bu HAFIRWGR--SLLETRRAGDVVRPHWLARAVRAHVRPD-RTGPPLSVRLV Mflv_5238|M.gilvum_PYR-GCK VPLAMWGARHQMADADVCHEAFRAEWLLSFLAADVRRDGPHDLDAVYEFH Mvan_1032|M.vanbaalenii_PYR-1 IPLAMWGARHQMSHADPCAEAFRAEWLLAFLAADLRGGIPEGLASVYEFH Mb1754c|M.bovis_AF2122/97 QTLGDWVS--RWLMADPTPAECDPELLTLWISRRVNTEALPGRRVVVEFR Rv1725c|M.tuberculosis_H37Rv QTLGDWVS--RWLMADPTPAECDPELLTLWISRRVNTEALPGRRVVVEFR MMAR_1626|M.marinum_M DALGEWGI--RWIP-ELGDEDLDPHLLMWDIRRTVPIDAWPRARTVLAFR MUL_3410|M.ulcerans_Agy99 DALGEWGI--RWIP-ELGDEDLDPHLLMWDIRRTVPIDAWPRARTVLAFR MAB_3456|M.abscessus_ATCC_1997 FALMEWGD-----------------------------------KFVTKG- .: * MSMEG_5032|M.smegmatis_MC2_155 TPE-----GQAAVEINEHTVESLDD--EADVDVTLTGAAEVLAAAMDPG- TH_2405|M.thermoresistible__bu TPE-----GAAAVRISADAVEDLDD--DTAVDVTLTGAAEVLAAALHPD- Mflv_5238|M.gilvum_PYR-GCK IDD-----STACLRLRDGGVTVTPGAPATPGDVVVRSRASTIAEIVGHKI Mvan_1032|M.vanbaalenii_PYR-1 VDD-----STACLQIRDGRVSVRPGPCATPADVTVRATARAIAAVVGQKD Mb1754c|M.bovis_AF2122/97 YHGERPLWA--WLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRVYSGRS Rv1725c|M.tuberculosis_H37Rv YHGERPLWA--WLVLEPGDISVCLHDPCLPVDLTVRGHPRDLYRVYSGRS MMAR_1626|M.marinum_M LAGVAPKAARWWLLVSEGEADVCDFDPGYQVAATVETSLLTLTQLWRGDQ MUL_3410|M.ulcerans_Agy99 LAGVAPKAARWWLLVSEGEADVCDFDPGYQVAATVETSLLTLTQLWRGDQ MAB_3456|M.abscessus_ATCC_1997 -----------------------------PPPSIWEHQCGSVLHIQPTCE : MSMEG_5032|M.smegmatis_MC2_155 QVENLVAAGLLTIDGDARAVRRLAKAFAPPRVRV---------------- TH_2405|M.thermoresistible__bu RAAELVAQGRLRVDGRADALRRLAEVVTAPAGRAVPDRS----------- Mflv_5238|M.gilvum_PYR-GCK AVADALADGSLEITGDADKISALVGVIEKRLAR----------------- Mvan_1032|M.vanbaalenii_PYR-1 RLEDAVAEGRIEVTGDPAAIATLIGAVEKRLA------------------ Mb1754c|M.bovis_AF2122/97 TLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQMPEAH Rv1725c|M.tuberculosis_H37Rv TLAAEISAERIELDGLPAMRRAFPSWMAWSPFAPAMRQAVVSVDQMPEAH MMAR_1626|M.marinum_M SWSRAMLNGGVRIDGPAQVRRSVPAWLGQSRLAAVPRPA----------- MUL_3410|M.ulcerans_Agy99 SWSRAMLNGGVRIDGPAQVRRSVPAWLGQSRLAAVPRPA----------- MAB_3456|M.abscessus_ATCC_1997 SCGEAVTFDDLTPRRLGRVR------------------------------ : : MSMEG_5032|M.smegmatis_MC2_155 -- TH_2405|M.thermoresistible__bu -- Mflv_5238|M.gilvum_PYR-GCK -- Mvan_1032|M.vanbaalenii_PYR-1 -- Mb1754c|M.bovis_AF2122/97 GG Rv1725c|M.tuberculosis_H37Rv GG MMAR_1626|M.marinum_M -- MUL_3410|M.ulcerans_Agy99 -- MAB_3456|M.abscessus_ATCC_1997 --