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GAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFGQLARNLNIPRPTLSSRLRMLVNAGLLDRV PYSQDPERHEYRLTDTGHELFAAIVVLMQWGDKHLPNPDGPPIVLRHHCGQFVEPRLICAHCGEEITARN VTPEAGPGFGDAVAAPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1555 | - | - | 100% (158) | transcriptional regulatory protein |
| M. marinum M | MMAR_1318 | - | 3e-15 | 35.83% (120) | transcriptional regulatory protein |
| M. marinum M | MMAR_1626 | - | 9e-12 | 39.36% (94) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3122 | - | 1e-72 | 80.89% (157) | putative transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_1806 | - | 2e-16 | 31.30% (131) | HxlR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3095 | - | 1e-72 | 80.89% (157) | putative transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3456 | - | 2e-26 | 41.22% (131) | HxlR family transcriptional regulator |
| M. avium 104 | MAV_4183 | - | 2e-14 | 34.71% (121) | putative transcriptional regulator family protein |
| M. smegmatis MC2 155 | MSMEG_6580 | - | 1e-21 | 48.51% (101) | transcriptional regulator family protein |
| M. thermoresistible (build 8) | TH_2405 | - | 4e-11 | 31.58% (133) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3475 | - | 1e-91 | 99.37% (158) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4941 | - | 2e-18 | 33.58% (137) | HxlR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4183|M.avium_104 MTLLQGPLADRDAWSAVGECAIEKTMAVVGTKSAMLIMREAYYGTTRFDD
MSMEG_6580|M.smegmatis_MC2_155 --------MGRKNVESL-DCSVARSLAVLGERWTILILREALLGTRRFAD
MMAR_1555|M.marinum_M -------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFGQ
MUL_3475|M.ulcerans_Agy99 -------MGAADLSHRFEGESVGRALELVGERWTLLILREAFFGVQRFGQ
Mb3122|M.bovis_AF2122/97 -------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQ
Rv3095|M.tuberculosis_H37Rv -------MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQ
Mflv_1806|M.gilvum_PYR-GCK ------------------------MLGLLGDEWTLLIVQRALLGARRYGE
Mvan_4941|M.vanbaalenii_PYR-1 --------------MAGTPNAVARMLSLLGDEWTLLIVQRALLGARRYGD
MAB_3456|M.abscessus_ATCC_1997 -----------MDFTTMRNCSISNALDVIGERWTLVALREIMLGNRRFET
TH_2405|M.thermoresistible__bu ----------MASRTYGQHCALAKSLDLVGDRWTLLIVRELLDGPRRYSD
: ::* . ::: ::. * *:
MAV_4183|M.avium_104 FARRVG-ITKAATSARLAELVELGLLKRRPYREPGQRSRDEYVLTQAGID
MSMEG_6580|M.smegmatis_MC2_155 FQSRLG-IGADMLSDRLSTLVEYGVLTKQPYQEPGQRPRAEYLLTPAGRE
MMAR_1555|M.marinum_M LARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
MUL_3475|M.ulcerans_Agy99 LARNLN-IPRPTLSSRLRMLVNAGLLDRVPYSQ--DPERHEYRLTDTGHE
Mb3122|M.bovis_AF2122/97 LARNLG-IPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
Rv3095|M.tuberculosis_H37Rv LARNLG-IPRPTLSSRLRMLVEVGLFDRVPYSS--DPERHEYRLTEAGRD
Mflv_1806|M.gilvum_PYR-GCK FLDALP-VSNAVLTSRLQSLSATEMLSRNQYQS--NPPRFEYLVTPMSRS
Mvan_4941|M.vanbaalenii_PYR-1 FAAALP-VSNTVLSGRLQSLTADGLLIRSQYQS--NPPRSEYLPTSMGRS
MAB_3456|M.abscessus_ATCC_1997 IVRNTG-ASRDILATRLRKLVDAGVLEKRRYED--RPPRYEYLLTQSGQA
TH_2405|M.thermoresistible__bu LLTALRPIATDMLATRLRHLEEHHLVRRRELPK--PASGTVYELTADGAA
: : ** * :. : . * * .
MAV_4183|M.avium_104 FMPVVWAMFEWGRRHLPGRHRLQLTHLGCGAEVGVEIRCAEGHLVPPDEL
MSMEG_6580|M.smegmatis_MC2_155 LHVLVAALQQWGDRHLPRPAGPTMTRKARRTDRPVRVAFID-DLGDEVPI
MMAR_1555|M.marinum_M LFAAIVVLMQWGDKHLPNPDGPPIVLRHH-CGQFVEPRLICAHCGEEITA
MUL_3475|M.ulcerans_Agy99 LFAAIVVLMQWGDKHLPNPDGPPIVLRHH-CGQFVEPRLICAHCGEEITA
Mb3122|M.bovis_AF2122/97 LFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITA
Rv3095|M.tuberculosis_H37Rv LFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITA
Mflv_1806|M.gilvum_PYR-GCK LWPMLTSIWEWERRWVTDHAEPLPRMRHTGCGHEFAPRVVCRSCTAEASG
Mvan_4941|M.vanbaalenii_PYR-1 LWPMLTSIWEWERRWVPEHAEPLPRMHHATCGRPFQPVVTCRACDGPASG
MAB_3456|M.abscessus_ATCC_1997 LRPVLFALMEWGDKFVTK--GPPPSIWEHQCGSVLHIQPTCESCGEAVTF
TH_2405|M.thermoresistible__bu LEAVVHAFIRWG-RSLLETRRAGDVVRPHWLARAVRAHVRPDRTGPPLSV
: : : .* . :
MAV_4183|M.avium_104 GMRLAKKSG-----------------------------------------
MSMEG_6580|M.smegmatis_MC2_155 NDVVSIPTGN----------------------------------------
MMAR_1555|M.marinum_M RNVTPEAGPG----------------------------------------
MUL_3475|M.ulcerans_Agy99 RNVTPEAGPG----------------------------------------
Mb3122|M.bovis_AF2122/97 RNVTPEPGPG----------------------------------------
Rv3095|M.tuberculosis_H37Rv RNVTPEPGPG----------------------------------------
Mflv_1806|M.gilvum_PYR-GCK NDVVAQWGPSGSWQRSIPGGTQRRRSSGHRSGAAILFPQTMSVIGDRWAF
Mvan_4941|M.vanbaalenii_PYR-1 KDVAAQWGPSGSWERSIPSGTNRRRSSGRRSGAALLFPQTMSVVGDRWAF
MAB_3456|M.abscessus_ATCC_1997 DDLTPR--------------------------------------------
TH_2405|M.thermoresistible__bu RLVTPEGAAAVR--------------------------------------
.
MAV_4183|M.avium_104 --------------------------------------------------
MSMEG_6580|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1555|M.marinum_M ---------------FGDAVAAPN--------------------------
MUL_3475|M.ulcerans_Agy99 ---------------YGDAVAAPN--------------------------
Mb3122|M.bovis_AF2122/97 ---------------FKAKLASS---------------------------
Rv3095|M.tuberculosis_H37Rv ---------------FKAKLASS---------------------------
Mflv_1806|M.gilvum_PYR-GCK AMLVAAFVGMRRFTDFQAQLGAPPTTVADRLTTFTDEGILVSGDGGYQFT
Mvan_4941|M.vanbaalenii_PYR-1 ALLVAAFVGVGRFTDFQAQLGAPPATIADRLSVFTDENILGQSGGRYGLT
MAB_3456|M.abscessus_ATCC_1997 ------------------RLGRVR--------------------------
TH_2405|M.thermoresistible__bu -----------ISADAVEDLDDDTAVDVTLTGAAEVLAAALHPDRAAELV
MAV_4183|M.avium_104 --------------------------------------------------
MSMEG_6580|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_1555|M.marinum_M --------------------------------------------------
MUL_3475|M.ulcerans_Agy99 --------------------------------------------------
Mb3122|M.bovis_AF2122/97 --------------------------------------------------
Rv3095|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1806|M.gilvum_PYR-GCK DKGRAFFPVLVCALSWAQRWFPSPEGPAVILTHTACGRRFDPVLRCDQCQ
Mvan_4941|M.vanbaalenii_PYR-1 EKGLAFFPVLVCALAWAQRWLPSPEGPAVLLTHTACDRRFAPVLVCDQCG
MAB_3456|M.abscessus_ATCC_1997 --------------------------------------------------
TH_2405|M.thermoresistible__bu AQGRLRVDGRADALRRLAEVVTAPAGRAVPDRS-----------------
MAV_4183|M.avium_104 ------------
MSMEG_6580|M.smegmatis_MC2_155 ------------
MMAR_1555|M.marinum_M ------------
MUL_3475|M.ulcerans_Agy99 ------------
Mb3122|M.bovis_AF2122/97 ------------
Rv3095|M.tuberculosis_H37Rv ------------
Mflv_1806|M.gilvum_PYR-GCK RHLRGAQIRPVP
Mvan_4941|M.vanbaalenii_PYR-1 NRLRAEQVLPVS
MAB_3456|M.abscessus_ATCC_1997 ------------
TH_2405|M.thermoresistible__bu ------------