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MTNLSRRSVLIGSLAVMAAAGVRMPTASAAPVDDRIADLERRNNASIGIYAVDLDSNRTVAHRADDSFAM CSTFKAYLAARILRGAERGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSDNAAANLL LKQIGGPAEITAFARSIGDQRTRLDRWETELNSAVPGDPRDTSTPAALAGGFRAVLTGDVLAPPQRQLLD EWMRANETSSLRAGLPDGWTSADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRTRGDDPNADGFRPLIG ELTALVLPELGVH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2658 | - | - | 100% (293) | beta-lactamase |
| M. smegmatis MC2 155 | MSMEG_2433 | - | 5e-07 | 29.70% (202) | D-alanyl-D-alanine carboxypeptidase |
| M. smegmatis MC2 155 | MSMEG_2432 | - | 3e-05 | 25.19% (262) | D-alanyl-D-alanine carboxypeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2094c | blaC | 2e-49 | 37.04% (297) | class A BETA-lactamase BLAC |
| M. gilvum PYR-GCK | Mflv_4021 | - | 6e-98 | 61.49% (296) | Beta-lactamase |
| M. tuberculosis H37Rv | Rv2068c | blaC | 2e-49 | 37.04% (297) | class A BETA-lactamase BLAC |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2875 | - | 2e-53 | 40.07% (292) | beta-lactamase |
| M. marinum M | MMAR_3050 | blaC | 7e-51 | 38.31% (295) | class a beta-lactamase, BlaC |
| M. avium 104 | MAV_3766 | - | 4e-06 | 29.50% (200) | D-alanyl-D-alanine carboxypeptidase |
| M. thermoresistible (build 8) | TH_1285 | - | 1e-102 | 62.93% (294) | beta-lactamase |
| M. ulcerans Agy99 | MUL_2294 | blaC | 5e-50 | 38.71% (279) | class a beta-lactamase, BlaC |
| M. vanbaalenii PYR-1 | Mvan_2352 | - | 1e-100 | 61.62% (297) | Beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_2658|M.smegmatis_MC2_155 ------MTNLSRRSVLIG--SLAVMAA--AGVRMP-TASAAP-----VDD
TH_1285|M.thermoresistible__bu ------VTGLSRRTLLIG--GLAVAGAGLCGLAAPRIAHAAPA----IHQ
Mflv_4021|M.gilvum_PYR-GCK ------MTELSRRHVLLGGLSLFALTACSTQTVLADPARPLPP----PEE
Mvan_2352|M.vanbaalenii_PYR-1 ------MTEFSRRHVLFGGVSLAALAACSPQTVLADPVEPLPP----LDQ
Mb2094c|M.bovis_AF2122/97 MR----NRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLAD
Rv2068c|M.tuberculosis_H37Rv MR----NRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLAD
MMAR_3050|M.marinum_M MRPSNPRSAVNRRQLLAAMAALLPLSACAKAASDQHMASTMAVPSPDLES
MUL_2294|M.ulcerans_Agy99 MRPSNPRSAVNRRQLLAAMAALVPLSACAKAASDQHLASTMAVPSPDLES
MAB_2875|M.abscessus_ATCC_1997 --------MISRRALLVGGVSAVGVVAAGCSRNGNRRPAP---------D
MAV_3766|M.avium_104 --MDRKLDFAAMRKLWTAAAALLLVGACGAPTAAADSTQPAG--------
* : . . .
MSMEG_2658|M.smegmatis_MC2_155 RIADLERRNNASIGIYAVDLDSNRTVAHRA-DDSFAMCSTFKAYLAARIL
TH_1285|M.thermoresistible__bu RLTGLENDHDQLIGLYAVDLGSGRTIAHRE-HESFAMCSTFKTYLAAATL
Mflv_4021|M.gilvum_PYR-GCK RIAALAARHDARIGLYAADLDSGATLAFGD-TDTFAVCSTFKTYAAGAVL
Mvan_2352|M.vanbaalenii_PYR-1 RIEALGQRHNAQIGLYALDLDTQRGIEFGA-DEPFAMCSTFKAYAAAAVL
Mb2094c|M.bovis_AF2122/97 RFAELERRYDARLGVYVPATGTTAAIEYRA-DERFAFCSTFKAPLVAAVL
Rv2068c|M.tuberculosis_H37Rv RFAELERRYDARLGVYVPATGTTAAIEYRA-DERFAFCSTFKAPLVAAVL
MMAR_3050|M.marinum_M RFAELEQKYEARLGVYVPGTDATAAVEHRG-DERFAFCSTFKGLLGAAVL
MUL_2294|M.ulcerans_Agy99 RFAELEQKYEARLGVYVPGTDATAAVEHRG-DERFAFCSTFKGLLGAAVL
MAB_2875|M.abscessus_ATCC_1997 ELASLEKDFGGRIGVYALDTGSGDTVGHRA-DERFLMCSTVKTFIVSAIL
MAV_3766|M.avium_104 ---SIPIPDGPAQTWIIADLDSGQVLAGRDPNVAHPPASTIKTLLAQVVL
: .: : . .**.* *
MSMEG_2658|M.smegmatis_MC2_155 RGAERGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSD
TH_1285|M.thermoresistible__bu QRVQQGELQLDQRIFVPPAAIVTHSPRSEAAAGGHLTVAELCAAILQVSD
Mflv_4021|M.gilvum_PYR-GCK QRVQQGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSD
Mvan_2352|M.vanbaalenii_PYR-1 QRTQTGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSD
Mb2094c|M.bovis_AF2122/97 HQ--NPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSD
Rv2068c|M.tuberculosis_H37Rv HQ--NPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSD
MMAR_3050|M.marinum_M HR--YPIAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSD
MUL_2294|M.ulcerans_Agy99 HR--YSIAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSD
MAB_2875|M.abscessus_ATCC_1997 RRRLSEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSD
MAV_3766|M.avium_104 DE-----VSLDATVVADAADTQVECNCVGIKPGRSYTARQLLDALLLVSG
*. : . : * * : *.
MSMEG_2658|M.smegmatis_MC2_155 NAAANLLLKQIGG----PAEITAFARSIGDQRTRLDRWETELNSAVPGDP
TH_1285|M.thermoresistible__bu NGAANTLLQTLGG----PPAVTEFARSIGDERSRLDRWEVALNSAVPGDP
Mflv_4021|M.gilvum_PYR-GCK NAAANGLLRVLGG----PSAITEFARSIGDDRTRLDRWEVELNSAVPGDP
Mvan_2352|M.vanbaalenii_PYR-1 NAAANGLLRVLGG----PQAITAFARSIGDHRTRLDRWEVELNSALPGDP
Mb2094c|M.bovis_AF2122/97 GTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDE
Rv2068c|M.tuberculosis_H37Rv GTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDE
MMAR_3050|M.marinum_M GTAANLLLQDIGG----IAAFNEYLRSLGDSVSRLDQMEPELNRNPPGDV
MUL_2294|M.ulcerans_Agy99 GTAANLLLQDIGG----IAAFNEYLRSLGDSVSRLDQMEPELNRNPPGDV
MAB_2875|M.abscessus_ATCC_1997 NTGANLLITQLGG----PKETEKFVRSLGDNVTRMDRTEVQLN-IPDGD-
MAV_3766|M.avium_104 NDAANTLAHMLGG----PEATVAKMNAKAAALGATNTHASTPSGLDGPNG
. .** * :** .: . : . :
MSMEG_2658|M.smegmatis_MC2_155 RDTSTPAALAGGFRAVLTGDVLAPPQRQLLDEWMRANETS--SLRAGLPD
TH_1285|M.thermoresistible__bu RDTSTPRALGEGYRTLLEGDVLAPPYREQLVEWMRTNETS--AMRPGLPP
Mflv_4021|M.gilvum_PYR-GCK RDTSTPRALATGYQALLTGDVLDPAGRRQLVDWMLANQTS--SMRAGLPA
Mvan_2352|M.vanbaalenii_PYR-1 RDTSTPRALGDGYRNILTGDVLNPPTRRQLLDWMLANQTS--SMRAGLPA
Mb2094c|M.bovis_AF2122/97 RDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPA
Rv2068c|M.tuberculosis_H37Rv RDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPA
MMAR_3050|M.marinum_M RDTTTPHAIAMDYQQVVLGDALLPEKRDKLIDWLGRSTTGAKRIRAGFPA
MUL_2294|M.ulcerans_Agy99 RDTTTPHAIAMDYQQVVLGDALLPEKRDKLIDWLGRSTTGAKRIRAGFPA
MAB_2875|M.abscessus_ATCC_1997 LDTSTPQQLVANLRRLVLDEGLDSRGRDLLTDWLKRNTTGDQSIRAAVPA
MAV_3766|M.avium_104 SGSSTAHDLAVIFRAAMANPVFAQITAEPSAMFPGDNGLQPITNQDELLQ
.::*. : : : . : : . : .
MSMEG_2658|M.smegmatis_MC2_155 GWT--SADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRTRGDDPNADGF
TH_1285|M.thermoresistible__bu GWV--SADKTGSGDYGTTNDVGLLYGPQGQRVVLAILTRSASDDPDAQNP
Mflv_4021|M.gilvum_PYR-GCK GYT--SADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRSASDDPDAPSL
Mvan_2352|M.vanbaalenii_PYR-1 GYT--SADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRSAIDDPDAPSL
Mb2094c|M.bovis_AF2122/97 DWK--VIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPR
Rv2068c|M.tuberculosis_H37Rv DWK--VIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPR
MMAR_3050|M.marinum_M DWR--VIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDRVGGGPEAPWC
MUL_2294|M.ulcerans_Agy99 DWR--VIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDRVGGGPEAPWC
MAB_2875|M.abscessus_ATCC_1997 GWT--VADKTGGGFKGETNDIAVIWPPGRAPIVMAVLT--VPEDPTSTKG
MAV_3766|M.avium_104 RYPGAIGGKTGFTNAARKTFVGAAARGGRRLVIAMMYGLIKEGGPSYWDQ
: .*** . . :. : : .
MSMEG_2658|M.smegmatis_MC2_155 RPLIGELTALVLPELGVH----
TH_1285|M.thermoresistible__bu RPLIGEITAAVLPELLGWPSAQ
Mflv_4021|M.gilvum_PYR-GCK RPLIGELATLVLSEL-------
Mvan_2352|M.vanbaalenii_PYR-1 RPLIGELAALALSELG------
Mb2094c|M.bovis_AF2122/97 EALLAEAATCVAGVLA------
Rv2068c|M.tuberculosis_H37Rv EALLAEAATCVAGVLA------
MMAR_3050|M.marinum_M DPLVADAAKCVADVLAQWSA--
MUL_2294|M.ulcerans_Agy99 DPLVADAAKCVADVLAQWSA--
MAB_2875|M.abscessus_ATCC_1997 KPTIAAATRIVLRAFGA-----
MAV_3766|M.avium_104 AATLFDWGFAQSPQASIGSL--
. :