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WRYAFGLVVLVVSGLITGPGSLAVPVARADADIQQVGSVAPPEGPAETWVVADMDTGQILAGRGEYVRHA PASTIKTLLALVVLDEVPLDSTIVADETDTDVECNCAGVAPGRTYTARQLLEAALLASGNDAANTLARML GGPEAAVAKMNAKAAQLGARDTNVVTPSGLDAPGMPFWSTPHDLAVIFRAAMADPVFAQITAMPSTVFPA KTGDRVLVNQNELLHRYPGTLGGKTGFTDIARKTFVAAAQRDGRRLVIAMMYGLVKEGGPTYWDQAAGLL DWGFAQDRSASIGAL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. smegmatis MC2 155 | MSMEG_2433 | - | - | 100% (296) | D-alanyl-D-alanine carboxypeptidase |
M. smegmatis MC2 155 | MSMEG_2432 | - | 1e-75 | 56.49% (262) | D-alanyl-D-alanine carboxypeptidase |
M. smegmatis MC2 155 | MSMEG_1661 | - | 8e-60 | 44.41% (286) | D-alanyl-D-alanine carboxypeptidase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2935 | dacB2 | 1e-107 | 68.36% (275) | D-alanyl-D-alanine carboxypeptidase |
M. gilvum PYR-GCK | Mflv_4179 | - | 1e-110 | 68.40% (288) | Serine-type D-Ala-D-Ala carboxypeptidase |
M. tuberculosis H37Rv | Rv2911 | dacB2 | 1e-107 | 68.36% (275) | D-alanyl-D-alanine carboxypeptidase |
M. leprae Br4923 | MLBr_00691 | - | 3e-56 | 43.06% (288) | putative D-alanyl-D-alanine carboxypeptidase |
M. abscessus ATCC 19977 | MAB_3234 | - | 1e-103 | 66.91% (275) | D-alanyl-D-alanine carboxypeptidase DacB |
M. marinum M | MMAR_1797 | dacB | 1e-108 | 66.20% (287) | D-alanyl-D-alanine carboxypeptidase DacB |
M. avium 104 | MAV_3766 | - | 1e-107 | 69.57% (276) | D-alanyl-D-alanine carboxypeptidase |
M. thermoresistible (build 8) | TH_2392 | - | 1e-119 | 70.89% (292) | D-alanyl-D-alanine carboxypeptidase |
M. ulcerans Agy99 | MUL_2045 | dacB | 1e-108 | 65.85% (287) | D-alanyl-D-alanine carboxypeptidase DacB |
M. vanbaalenii PYR-1 | Mvan_2184 | - | 1e-111 | 69.34% (287) | Serine-type D-Ala-D-Ala carboxypeptidase |
CLUSTAL 2.0.9 multiple sequence alignment MSMEG_2433|M.smegmatis_MC2_155 ----------------MWRYA--FGLVVLVVSGLITGPGSLAVPVARADA TH_2392|M.thermoresistible__bu ----------------MGRFAGAFALLLIAVLSVVAPGAPVTDPVAWADP Mflv_4179|M.gilvum_PYR-GCK MNTTGRAGRGWIDFPVMTRLLASLGAALCLILAGSGVVSPTASAVP-VTG Mvan_2184|M.vanbaalenii_PYR-1 ----------------MTRLLACLGAVLCLVGS---VSVPHAAAVP-ATG Mb2935|M.bovis_AF2122/97 -----------------------MRKLMTATAALCACAVTVSAGAAWADA Rv2911|M.tuberculosis_H37Rv -----------------------MRKLMTATAALCACAVTVSAGAAWADA MMAR_1797|M.marinum_M -----------------------MRKVMAVAAALLT-AATISGATASADT MUL_2045|M.ulcerans_Agy99 -----------------------MRKVMAVAAVLLT-AATISGATASADT MAV_3766|M.avium_104 --------------MDRKLDFAAMRKLWTAAAALLL--VGACGAPTAAAD MAB_3234|M.abscessus_ATCC_1997 -------------------MSDPMSTLRIRALAVLSVLFLSTLPVGVARA MLBr_00691|M.leprae_Br4923 --------------MSFLRSTACLAAAVFAIVGPVALDLPTAVPVGHAEP : . MSMEG_2433|M.smegmatis_MC2_155 DIQQ---------------------------------------------- TH_2392|M.thermoresistible__bu EIRP---------------------------------------------- Mflv_4179|M.gilvum_PYR-GCK IVQP---------------------------------------------- Mvan_2184|M.vanbaalenii_PYR-1 IVQP---------------------------------------------- Mb2935|M.bovis_AF2122/97 DVQP---------------------------------------------- Rv2911|M.tuberculosis_H37Rv DVQP---------------------------------------------- MMAR_1797|M.marinum_M EMQP---------------------------------------------- MUL_2045|M.ulcerans_Agy99 EMQP---------------------------------------------- MAV_3766|M.avium_104 STQP---------------------------------------------- MAB_3234|M.abscessus_ATCC_1997 DMA----------------------------------------------- MLBr_00691|M.leprae_Br4923 NAGPNAGPATCPYQVSTPPAVDSSEVPQTGNPPMPLAVPPKPVGGAALNS MSMEG_2433|M.smegmatis_MC2_155 VGSVAPPEGP-------AETWVVADMDTGQILAGRGEYVRHAPASTIKTL TH_2392|M.thermoresistible__bu VGSVPAPTGP-------AQAWIVADLDTGEVLAGRNENTRYAPASTIKTL Mflv_4179|M.gilvum_PYR-GCK AGSVPVPDGP-------AQAWVLADMDTGAVLAARQENGRFAPASTIKIL Mvan_2184|M.vanbaalenii_PYR-1 AGSMPIPDGP-------AQAWIVADMDTGAVLAARDEHGHFAPASTIKVL Mb2935|M.bovis_AF2122/97 AGSVPIPDGP-------AQTWIVADLDSGQVLAGRDQNVAHPPASTIKVL Rv2911|M.tuberculosis_H37Rv AGSVPIPDGP-------AQTWIVADLDSGQVLAGRDQNVAHPPASTIKVL MMAR_1797|M.marinum_M AGSVPIPDGP-------AQTWIVADLDTGQVLAGRDQNVTHPPASTIKVL MUL_2045|M.ulcerans_Agy99 AGSVPIPDGP-------AQTWIVADLDTGQVLAGRDQNVTHPPASTIKVL MAV_3766|M.avium_104 AGSIPIPDGP-------AQTWIIADLDSGQVLAGRDPNVAHPPASTIKTL MAB_3234|M.abscessus_ATCC_1997 ---APPPEGP-------AQAWLVADLDSGQILAARDPYATHAPASTIKVL MLBr_00691|M.leprae_Br4923 CGIVTAPDTPPVPGDLSAEAWLVADLNSGAVIAARDPHGRHRPASIIKVL . * * *::*::**:::* ::*.* . *** ** * MSMEG_2433|M.smegmatis_MC2_155 LALVVLDEVPLDSTIVADETDTDVECNCAGVAPGRTYTARQLLEAALLAS TH_2392|M.thermoresistible__bu LAQVVLDEVPLDATIVATDEDTEVICNCAGVAPGHTYTTRQLLEGLLLAS Mflv_4179|M.gilvum_PYR-GCK LAMVVLDELPLDATVVANEADTRVECNCAGVAPGTTYTTRQLLEGLLLVS Mvan_2184|M.vanbaalenii_PYR-1 LAMVVLDELPLDATIVANEADTLVECNCAGVTPGRTYTTRQLLEALLLVS Mb2935|M.bovis_AF2122/97 LALVALDELDLNSTVVADVADTQAECNCVGVKPGRSYTARQLLDGLLLVS Rv2911|M.tuberculosis_H37Rv LALVALDELDLNSTVVADVADTQAECNCVGVKPGRSYTARQLLDGLLLVS MMAR_1797|M.marinum_M LALVALDELDLNSTVVADEADTHVECNCVGVKAGHTYTARQLLDGLLLVS MUL_2045|M.ulcerans_Agy99 LALVALDELNLNSTVVADEADTHVECNCVGVKAGHTYTARQLLDGLLLVS MAV_3766|M.avium_104 LAQVVLDEVSLDATVVADAADTQVECNCVGIKPGRSYTARQLLDALLLVS MAB_3234|M.abscessus_ATCC_1997 LALVALDEVPMDATVVADAADAKAECNCVGIKAGQTYTARELLDAALLES MLBr_00691|M.leprae_Br4923 LAMASINTLNLNKSVAGTAEDAAAEGTKVGVHDGGTYTINQLLHGLLMQS ** . :: : :: ::.. *: . . .*: * :** .:**.. *: * MSMEG_2433|M.smegmatis_MC2_155 GNDAANTLARMLGGPEAAVAKMNAKAAQLGARDTNVVTPSGLDAPGMPFW TH_2392|M.thermoresistible__bu GNDAANTLARMLGGEQAAVAKMNALAGRLGAHGTTVASTSGLDVPGVPFW Mflv_4179|M.gilvum_PYR-GCK GNDAANTLATMLGGRDAAVAKMNAKAAGLGAHGTRAGSPSGIDGPGIDIW Mvan_2184|M.vanbaalenii_PYR-1 GNDAANTLATMLGGRDVAVMKMNAKAATLGAYGTNAGSPSGIDGPGIDIW Mb2935|M.bovis_AF2122/97 GNDAANTLAHMLGGQDVTVAKMNAKAATLGATSTHATTPSGLDGPGGSGA Rv2911|M.tuberculosis_H37Rv GNDAANTLAHMLGGQDVTVAKMNAKAATLGATSTHATTPSGLDGPGGSGA MMAR_1797|M.marinum_M GNDAANTLAQMLGGQDAAVAKMNAKAAALGAMNTHAATPSGLDGPGGSGW MUL_2045|M.ulcerans_Agy99 GNDAANTLAQLLGGQDAAVAKMNAKAAALGAMNTHAATPSGLDGPGGSGW MAV_3766|M.avium_104 GNDAANTLAHMLGGPEATVAKMNAKAAALGATNTHASTPSGLDGPNGSGS MAB_3234|M.abscessus_ATCC_1997 GNDAANTLAHLLGGRQATVDKMNAKAAALGATSTHTDSPSGLDAPGMDMR MLBr_00691|M.leprae_Br4923 GNDAAHSLAMQLGGMQQALQKINVLAAKLGGQDTRVATPSGLDGPGMS-- *****::** *** : :: *:*. *. **. .* . :.**:* *. MSMEG_2433|M.smegmatis_MC2_155 STPHDLAVIFRAAMADPVFAQITAMPSTVFP--AKTGDRVLVNQNELLHR TH_2392|M.thermoresistible__bu STPHDLAVIFRAALNHPVFAEITAMPSAVFP--ARRGEMVLVNQNELLQR Mflv_4179|M.gilvum_PYR-GCK STPRDLAVLFRAAMAYPVFAQITAQPTAVFP--TKSGDVVLVNQDEMLHR Mvan_2184|M.vanbaalenii_PYR-1 STPRDLAVIFRAAMADPVFAQIVAQPTAVFP--AKTGDVVLVNQDELLHR Mb2935|M.bovis_AF2122/97 STAHDLVVIFRAAMANPVFAQITAEPSAMFP--SDNGEQLIVNQDELLQR Rv2911|M.tuberculosis_H37Rv STAHDLVVIFRAAMANPVFAQITAEPSAMFP--SDNGEQLIVNQDELLQR MMAR_1797|M.marinum_M STAHDLAVIFRTAMANPVFAHITAEPSAMFP--GEDGEHPIVNQDELLQR MUL_2045|M.ulcerans_Agy99 STAHDLAVIFRTAMANPVFAHITAEPSAMFP--GEDGEHPIVNQDELLQR MAV_3766|M.avium_104 STAHDLAVIFRAAMANPVFAQITAEPSAMFP--GDNGLQPITNQDELLQR MAB_3234|M.abscessus_ATCC_1997 TSPHDLAVIFRAALANPVFAEITAQPSAPFP--GRG----LHNQNELMYR MLBr_00691|M.leprae_Br4923 TSAYDIGLFYRYAWQNPSFSNIVATRTFNFPGPGDHPGYQLENDNQLLYQ ::. *: :::* * * *:.*.* : ** : *::::: : MSMEG_2433|M.smegmatis_MC2_155 YPGTLGGKTGFTDIARKTFVAAAQRDGRRLVIAMMYGLVKEGGPTYWDQA TH_2392|M.thermoresistible__bu YPGALGGKTGYTDIARKTYVGAAQRDGRRLVVALMYGLVADGGPTYWDQA Mflv_4179|M.gilvum_PYR-GCK YPGTFGGKTGYTDLARKTFVAGASRNGRHLVVAMMYGLVTEGGPTYWDQA Mvan_2184|M.vanbaalenii_PYR-1 YPGTFGGKTGYTDLARKTFVGGAARNGRHLVVALMYGLVKEGGPTYWDQA Mb2935|M.bovis_AF2122/97 YPGAIGGKTGYTNAARKTFVGAAARGGRRLVIAMMYGLVKEGGPTYWDQA Rv2911|M.tuberculosis_H37Rv YPGAIGGKTGYTNAARKTFVGAAARGGRRLVIAMMYGLVKEGGPTYWDQA MMAR_1797|M.marinum_M YPGAIGGKTGYTNAARKTFVGAAARNGRRLVIAMMYGLVKEGGPTYWDQA MUL_2045|M.ulcerans_Agy99 YPGAIGGKTGYTNAARKTFVGAAARNGRRLVIAMMYGLVKEGGPTYWDQA MAV_3766|M.avium_104 YPGAIGGKTGFTNAARKTFVGAAARGGRRLVIAMMYGLIKEGGPSYWDQA MAB_3234|M.abscessus_ATCC_1997 YPGVIGGKTGFTDIARKTYVVAAERDGKRLVVSMMYGLVHEGGPTYWDQA MLBr_00691|M.leprae_Br4923 YPGALGGKTGYTDDAGQTFVGAANRNGRRLMAVLLHGTRQPIAP--WEQA ***.:*****:*: * :*:* .* *.*::*: :::* .* *:** MSMEG_2433|M.smegmatis_MC2_155 AGLLDWGFAQDRSASIGAL------------------------------- TH_2392|M.thermoresistible__bu TALLDWGFSQDTGTAIGVL------------------------------- Mflv_4179|M.gilvum_PYR-GCK SALLDWGFALGPNAGVSRL------------------------------- Mvan_2184|M.vanbaalenii_PYR-1 AALLDWGFALGPNSGVSRL------------------------------- Mb2935|M.bovis_AF2122/97 ATLFDWGFALNPQASVGSL------------------------------- Rv2911|M.tuberculosis_H37Rv ATLFDWGFALNPQASVGSL------------------------------- MMAR_1797|M.marinum_M GSLFDWGFALNPQSGIGSL------------------------------- MUL_2045|M.ulcerans_Agy99 GSLFDWGFALNPQSGIGSL------------------------------- MAV_3766|M.avium_104 ATLFDWGFAQSPQASIGSL------------------------------- MAB_3234|M.abscessus_ATCC_1997 ASLFDWGFVNDGSSSVGSL------------------------------- MLBr_00691|M.leprae_Br4923 AHLLDYGFSTAVGTQIGTLIEPDPTVAGNADRHGHGLQAAGIMSSNDTLP *:*:** : :. * MSMEG_2433|M.smegmatis_MC2_155 ----------------------------- TH_2392|M.thermoresistible__bu ----------------------------- Mflv_4179|M.gilvum_PYR-GCK ----------------------------- Mvan_2184|M.vanbaalenii_PYR-1 ----------------------------- Mb2935|M.bovis_AF2122/97 ----------------------------- Rv2911|M.tuberculosis_H37Rv ----------------------------- MMAR_1797|M.marinum_M ----------------------------- MUL_2045|M.ulcerans_Agy99 ----------------------------- MAV_3766|M.avium_104 ----------------------------- MAB_3234|M.abscessus_ATCC_1997 ----------------------------- MLBr_00691|M.leprae_Br4923 VRIGVAVVGTLIVFGLIMITRSLNRRPQH