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M. thermoresistible (build 8) TH_1285 (-)

annotation: beta-lactamase
coordinates: 2444568 - 2445473
length: 302

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1285--100% (302)beta-lactamase
M. thermoresistible (build 8)TH_2392-1e-0729.82% (228) D-alanyl-D-alanine carboxypeptidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2094cblaC5e-4236.67% (300) class A BETA-lactamase BLAC
M. gilvum PYR-GCKMflv_4021-6e-9660.40% (298) Beta-lactamase
M. tuberculosis H37RvRv2068cblaC5e-4236.67% (300) class A BETA-lactamase BLAC
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2875-8e-5038.97% (290) beta-lactamase
M. marinum MMMAR_3050blaC2e-4636.18% (304) class a beta-lactamase, BlaC
M. avium 104MAV_3766-9e-0635.71% (98) D-alanyl-D-alanine carboxypeptidase
M. smegmatis MC2 155MSMEG_2658-1e-10262.93% (294) beta-lactamase
M. ulcerans Agy99MUL_2294blaC2e-4636.18% (304) class a beta-lactamase, BlaC
M. vanbaalenii PYR-1Mvan_2352-6e-9459.06% (298) Beta-lactamase

CLUSTAL 2.0.9 multiple sequence alignment


TH_1285|M.thermoresistible__bu      ------VTGLSRRTLLIG--GLAVAGAGLCGLAAPRIAHAAPA----IHQ
MSMEG_2658|M.smegmatis_MC2_155      ------MTNLSRRSVLIG--SLAVMAA--AGVRMP-TASAAP-----VDD
Mflv_4021|M.gilvum_PYR-GCK          ------MTELSRRHVLLGGLSLFALTACSTQTVLADPARPLPP----PEE
Mvan_2352|M.vanbaalenii_PYR-1       ------MTEFSRRHVLFGGVSLAALAACSPQTVLADPVEPLPP----LDQ
Mb2094c|M.bovis_AF2122/97           MR----NRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLAD
Rv2068c|M.tuberculosis_H37Rv        MR----NRGFGRRELLVAMAMLVSVTGCARHASGARPASTTLPAGADLAD
MMAR_3050|M.marinum_M               MRPSNPRSAVNRRQLLAAMAALLPLSACAKAASDQHMASTMAVPSPDLES
MUL_2294|M.ulcerans_Agy99           MRPSNPRSAVNRRQLLAAMAALVPLSACAKAASDQHLASTMAVPSPDLES
MAB_2875|M.abscessus_ATCC_1997      --------MISRRALLVGGVSAVGVVAAGCSRNGNRRPAP---------D
MAV_3766|M.avium_104                --MDRKLDFAAMRKLWTAAAALLLVGACGAPTAAADSTQPAG--------
                                                * :  .        .            .          

TH_1285|M.thermoresistible__bu      RLTGLENDHDQLIGLYAVDLGSGRTIAHRE-HESFAMCSTFKTYLAAATL
MSMEG_2658|M.smegmatis_MC2_155      RIADLERRNNASIGIYAVDLDSNRTVAHRA-DDSFAMCSTFKAYLAARIL
Mflv_4021|M.gilvum_PYR-GCK          RIAALAARHDARIGLYAADLDSGATLAFGD-TDTFAVCSTFKTYAAGAVL
Mvan_2352|M.vanbaalenii_PYR-1       RIEALGQRHNAQIGLYALDLDTQRGIEFGA-DEPFAMCSTFKAYAAAAVL
Mb2094c|M.bovis_AF2122/97           RFAELERRYDARLGVYVPATGTTAAIEYRA-DERFAFCSTFKAPLVAAVL
Rv2068c|M.tuberculosis_H37Rv        RFAELERRYDARLGVYVPATGTTAAIEYRA-DERFAFCSTFKAPLVAAVL
MMAR_3050|M.marinum_M               RFAELEQKYEARLGVYVPGTDATAAVEHRG-DERFAFCSTFKGLLGAAVL
MUL_2294|M.ulcerans_Agy99           RFAELEQKYEARLGVYVPGTDATAAVEHRG-DERFAFCSTFKGLLGAAVL
MAB_2875|M.abscessus_ATCC_1997      ELASLEKDFGGRIGVYALDTGSGDTVGHRA-DERFLMCSTVKTFIVSAIL
MAV_3766|M.avium_104                ---SIPIPDGPAQTWIIADLDSGQVLAGRDPNVAHPPASTIKTLLAQVVL
                                        :               .:   :        .  .**.*       *

TH_1285|M.thermoresistible__bu      QRVQQGELQLDQRIFVPPAAIVTHSPRSEAAAGGHLTVAELCAAILQVSD
MSMEG_2658|M.smegmatis_MC2_155      RGAERGELSLDDRVFVDPAALLSNSPITETHAGGEMTLAELCQAALQRSD
Mflv_4021|M.gilvum_PYR-GCK          QRVQQGRLGLGDTVLIEAADIRPHSPVTEPRVGTAMTLAELCQAALQQSD
Mvan_2352|M.vanbaalenii_PYR-1       QRTQTGELTLNDAIPIEPGDIRPHSPVTEPRVGTSMSLAELCQAALQQSD
Mb2094c|M.bovis_AF2122/97           HQ--NPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSD
Rv2068c|M.tuberculosis_H37Rv        HQ--NPLTHLDKLITYTSDDIRSISPVAQQHVQTGMTIGQLCDAAIRYSD
MMAR_3050|M.marinum_M               HR--YPIAHLGTVITYNSADIRSTSPITEQHLATGMSIGGLCDATIRYSD
MUL_2294|M.ulcerans_Agy99           HR--YSIAHLGTVITYNSADIRSTSPIIEQHLATGMSIGGLCDATIRYSD
MAB_2875|M.abscessus_ATCC_1997      RRRLSEPGLLDQRIQYTQSDVLEWAPITSQHVSTGMTVSELCDATLRYSD
MAV_3766|M.avium_104                DE-----VSLDATVVADAADTQVECNCVGIKPGRSYTARQLLDALLLVSG
                                             *.  :          .           :   *  * :  *.

TH_1285|M.thermoresistible__bu      NGAANTLLQTLGG----PPAVTEFARSIGDERSRLDRWEVALNSAVPGDP
MSMEG_2658|M.smegmatis_MC2_155      NAAANLLLKQIGG----PAEITAFARSIGDQRTRLDRWETELNSAVPGDP
Mflv_4021|M.gilvum_PYR-GCK          NAAANGLLRVLGG----PSAITEFARSIGDDRTRLDRWEVELNSAVPGDP
Mvan_2352|M.vanbaalenii_PYR-1       NAAANGLLRVLGG----PQAITAFARSIGDHRTRLDRWEVELNSALPGDP
Mb2094c|M.bovis_AF2122/97           GTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDE
Rv2068c|M.tuberculosis_H37Rv        GTAANLLLADLGGPGGGTAAFTGYLRSLGDTVSRLDAEEPELNRDPPGDE
MMAR_3050|M.marinum_M               GTAANLLLQDIGG----IAAFNEYLRSLGDSVSRLDQMEPELNRNPPGDV
MUL_2294|M.ulcerans_Agy99           GTAANLLLQDIGG----IAAFNEYLRSLGDSVSRLDQMEPELNRNPPGDV
MAB_2875|M.abscessus_ATCC_1997      NTGANLLITQLGG----PKETEKFVRSLGDNVTRMDRTEVQLN-IPDGD-
MAV_3766|M.avium_104                NDAANTLAHMLGG----PEATVAKMNAKAAALGATNTHASTPSGLDGPNG
                                    . .** *   :**            .: .      :      .     : 

TH_1285|M.thermoresistible__bu      RDTSTPRALGEGYRTLLEGDVLAPPYREQLVEWMRTNETS--AMRPGLPP
MSMEG_2658|M.smegmatis_MC2_155      RDTSTPAALAGGFRAVLTGDVLAPPQRQLLDEWMRANETS--SLRAGLPD
Mflv_4021|M.gilvum_PYR-GCK          RDTSTPRALATGYQALLTGDVLDPAGRRQLVDWMLANQTS--SMRAGLPA
Mvan_2352|M.vanbaalenii_PYR-1       RDTSTPRALGDGYRNILTGDVLNPPTRRQLLDWMLANQTS--SMRAGLPA
Mb2094c|M.bovis_AF2122/97           RDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPA
Rv2068c|M.tuberculosis_H37Rv        RDTTTPHAIALVLQQLVLGNALPPDKRALLTDWMARNTTGAKRIRAGFPA
MMAR_3050|M.marinum_M               RDTTTPHAIAMDYQQVVLGDALLPEKRDKLIDWLGRSTTGAKRIRAGFPA
MUL_2294|M.ulcerans_Agy99           RDTTTPHAIAMDYQQVVLGDALLPEKRDKLIDWLGRSTTGAKRIRAGFPA
MAB_2875|M.abscessus_ATCC_1997      LDTSTPQQLVANLRRLVLDEGLDSRGRDLLTDWLKRNTTGDQSIRAAVPA
MAV_3766|M.avium_104                SGSSTAHDLAVIFRAAMANPVFAQITAEPSAMFPGDNGLQPITNQDELLQ
                                     .::*.  :    :  : .  :          :   .       :  .  

TH_1285|M.thermoresistible__bu      GWV--SADKTGSGDYGTTNDVGLLYGPQGQRVVLAILTRSASDDPDAQNP
MSMEG_2658|M.smegmatis_MC2_155      GWT--SADKTGSGDYGSTNDVGIAYGPQGQRILLALMVRTRGDDPNADGF
Mflv_4021|M.gilvum_PYR-GCK          GYT--SADKTGSGDYGSTNDVGIAFGPAGQRLLLAVMTRSASDDPDAPSL
Mvan_2352|M.vanbaalenii_PYR-1       GYT--SADKTGSGDYGTTNDVGVAYGPAGQQVLLSLMTRSAIDDPDAPSL
Mb2094c|M.bovis_AF2122/97           DWK--VIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPR
Rv2068c|M.tuberculosis_H37Rv        DWK--VIDKTGTGDYGRANDIAVVWSPTGVPYVVAVMSDRAGGGYDAEPR
MMAR_3050|M.marinum_M               DWR--VIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDRVGGGPEAPWC
MUL_2294|M.ulcerans_Agy99           DWR--VIDKTGSGEYGRANDVAVVWSPGGTPYVVAIMTDRVGGGPEAPWC
MAB_2875|M.abscessus_ATCC_1997      GWT--VADKTGGGFKGETNDIAVIWPPGRAPIVMAVLT--VPEDPTSTKG
MAV_3766|M.avium_104                RYPGAIGGKTGFTNAARKTFVGAAARGGRRLVIAMMYGLIKEGGPSYWDQ
                                     :     .***    .  . :.          :  :       .      

TH_1285|M.thermoresistible__bu      RPLIGEITAAVLPELLGWPSAQ
MSMEG_2658|M.smegmatis_MC2_155      RPLIGELTALVLPELGVH----
Mflv_4021|M.gilvum_PYR-GCK          RPLIGELATLVLSEL-------
Mvan_2352|M.vanbaalenii_PYR-1       RPLIGELAALALSELG------
Mb2094c|M.bovis_AF2122/97           EALLAEAATCVAGVLA------
Rv2068c|M.tuberculosis_H37Rv        EALLAEAATCVAGVLA------
MMAR_3050|M.marinum_M               DPLVADAAKCVADVLAQWSA--
MUL_2294|M.ulcerans_Agy99           DPLVADAAKCVADVLAQWSA--
MAB_2875|M.abscessus_ATCC_1997      KPTIAAATRIVLRAFGA-----
MAV_3766|M.avium_104                AATLFDWGFAQSPQASIGSL--
                                     . :