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VAKPKKTAKYDLKAADRKRNLLVQIGLTAVVVLFAVALVLYIVMNGEKNPDAGAGKAIRVASSDVVTDEG SSDPKVVLGLYEDFLCPACGNFERSFGPTISKLIDSGAIAADYYMVGILDRAGNGYSSRAGGAGYCVADE STDAFRRFHTALYTPELQPQENSGIYPDNARLIELARQAGAAGKVADCINNGRYVEMVKGMAAATGINAT PTIRINGEDYSPTTPDALVAKVKEIVGEVPGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2410 | - | - | 100% (242) | putative serine-threonine protein kinase |
| M. smegmatis MC2 155 | MSMEG_1111 | - | 8e-12 | 24.51% (204) | hypothetical protein MSMEG_1111 |
| M. smegmatis MC2 155 | MSMEG_1215 | - | 6e-09 | 29.73% (148) | serine/threonine-protein kinase PknE, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2993c | - | 1e-81 | 60.91% (243) | hypothetical protein Mb2993c |
| M. gilvum PYR-GCK | Mflv_4202 | - | 1e-92 | 68.18% (242) | hypothetical protein Mflv_4202 |
| M. tuberculosis H37Rv | Rv2969c | - | 1e-81 | 60.91% (243) | hypothetical protein Rv2969c |
| M. leprae Br4923 | MLBr_01667 | - | 1e-71 | 53.69% (244) | hypothetical protein MLBr_01667 |
| M. abscessus ATCC 19977 | MAB_3269c | - | 2e-65 | 51.95% (256) | hypothetical protein MAB_3269c |
| M. marinum M | MMAR_1747 | - | 3e-78 | 58.02% (243) | hypothetical protein MMAR_1747 |
| M. avium 104 | MAV_3813 | - | 6e-84 | 64.46% (242) | hypothetical protein MAV_3813 |
| M. thermoresistible (build 8) | TH_2711 | - | 1e-06 | 28.72% (94) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_1990 | - | 1e-77 | 57.61% (243) | hypothetical protein MUL_1990 |
| M. vanbaalenii PYR-1 | Mvan_2163 | - | 1e-95 | 70.54% (241) | hypothetical protein Mvan_2163 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4202|M.gilvum_PYR-GCK ------MASKPKKNARYDLKAADR-KRNLLIQIGLTAVVVIFAVALVLYI
Mvan_2163|M.vanbaalenii_PYR-1 ------MATKPKKNARYDLKAADR-KRNLLVQIGLTAVVVIFAVTLVLYI
MSMEG_2410|M.smegmatis_MC2_155 -------MAKPKKTAKYDLKAADR-KRNLLVQIGLTAVVVLFAVALVLYI
MLBr_01667|M.leprae_Br4923 MRISEPVADNRKRLQRFDLKSVDG-RSGRAVVIAGTVIVAIFAVVVVFAV
MAV_3813|M.avium_104 ------MADNPKRPPRFDMKSASGGKSGRLVQIGGTAFVVIFAVALVFYI
Mb2993c|M.bovis_AF2122/97 ------MADKSKRPPRFDLKSADG-SFGRLVQIGGTTIVVVFAVVLVFYI
Rv2969c|M.tuberculosis_H37Rv ------MADKSKRPPRFDLKSADG-SFGRLVQIGGTTIVVVFAVVLVFYI
MMAR_1747|M.marinum_M ------MADKNKRPPRIDLNSPDG-KFGRLIQIGGTAFVVFFAVALVFYI
MUL_1990|M.ulcerans_Agy99 ------MADKNKRPTRIDLNSPDG-KFGRLIQIGGTAFVVFFAVALVFYI
MAB_3269c|M.abscessus_ATCC_199 -------MAKPKQPPSYDLKKAEQ-RRSQLIQIGLTAIVVLFAVGLVGFI
TH_2711|M.thermoresistible__bu --------------------------MRWLTLTAMLGVAVLLSGCTVTVD
. ....:: *
Mflv_4202|M.gilvum_PYR-GCK VGSADDKP-----TAGESRGIRVES---TSVIKKEGTDEPKAVVSMYEDF
Mvan_2163|M.vanbaalenii_PYR-1 VLSADDKP-----TAGESRAIRVES---TSVIKKDGTDEPKAVLSMYEDF
MSMEG_2410|M.smegmatis_MC2_155 VMNGEKNP-----DAGAGKAIRVAS---SDVVTDEGSSDPKVVLGLYEDF
MLBr_01667|M.leprae_Br4923 MKSQHAKQDGAAPLTGSGDTVRVTS---SKLVTQPGTHDPKVVMSFYEDF
MAV_3813|M.avium_104 VTSHHKK----AGPTGAGDTVRVTS---SKLITQPGSSNPKAVVTLYEDF
Mb2993c|M.bovis_AF2122/97 VTSRDDKK---DGVAGPGDAVRVTS---SKLVTQPGTSNPKAVVSFYEDF
Rv2969c|M.tuberculosis_H37Rv VTSRDDKK---DGVAGPGDAVRVTS---SKLVTQPGTSNPKAVVSFYEDF
MMAR_1747|M.marinum_M VTSHQKKG---GGAAGPDDSVRVTS---SKLVTQPGTQDPKVVMTFYEDF
MUL_1990|M.ulcerans_Agy99 VTSHQKKG---GGAAGPDDSVRVTS---SKLVTQPGTQDPKVVMTFYEDF
MAB_3269c|M.abscessus_ATCC_199 VLSNKKDEGPPAPPAGEVKAIQVVTPGPAKLITKEGTTEPKVVLTLIEDP
TH_2711|M.thermoresistible__bu GAASAPAD-----APGDATVVVAED----GYGVELGYQFAPARIEIYIEP
.* : . . * . . : : :
Mflv_4202|M.gilvum_PYR-GCK LCPHCGAFEQQFGPTINKLVDAGAIAADYYMVGILDRPQNQ-NYPARAGG
Mvan_2163|M.vanbaalenii_PYR-1 LCPHCGAFEQQFGPTISKLIDSGAIAADYYMVGILDRSQNQ-NYPSRAGG
MSMEG_2410|M.smegmatis_MC2_155 LCPACGNFERSFGPTISKLIDSGAIAADYYMVGILDRAGN--GYSSRAGG
MLBr_01667|M.leprae_Br4923 LCPGCGDFERNFGPTVSKLIDIGAIAADYSVVSILDHPRNH-NYPSRAGA
MAV_3813|M.avium_104 LCPACGNFERTFGPTVSKLIDLGAIAADYSMVSILDSPRNQ-NYSSRAGA
Mb2993c|M.bovis_AF2122/97 LCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQ-HYSSRAAA
Rv2969c|M.tuberculosis_H37Rv LCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQ-HYSSRAAA
MMAR_1747|M.marinum_M LCPACGMFERAFGPTVSRLVDIGAVAADYTMVDILSSPRNQ-NYSARAAA
MUL_1990|M.ulcerans_Agy99 LCPACGMFERAFGPTVSRLVDIGAVAADYTMVDILSSPRNQ-NYSARAAA
MAB_3269c|M.abscessus_ATCC_199 ICPACAMFEQEFGPTVKKLIDTGAVRADYDMVGILDVPRLKRDYSSRASA
TH_2711|M.thermoresistible__bu LCPACARLQRRYGEDLRSAIERDELRVTYRPLTFLDRSGG---YSKRVSN
:** *. ::: :* : :: . : . * : :*. . *. *..
Mflv_4202|M.gilvum_PYR-GCK AAYCVADESIDAFKRFHAALYA--QQPGET-GSTYPDNARLIEIARQSGA
Mvan_2163|M.vanbaalenii_PYR-1 AAYCVADESVDAFRRFHAALYA--QQPSEA-GSAYPDNARLIEVARQSGA
MSMEG_2410|M.smegmatis_MC2_155 AGYCVADESTDAFRRFHTALYTPELQPQEN-SGIYPDNARLIELARQAGA
MLBr_01667|M.leprae_Br4923 ASLCVADESMDAYRRFRAALYSRSFQPSEL-ASSFPENAKLIEIAREAGV
MAV_3813|M.avium_104 AALCVADESLDAFRRFHTALFSTAIQPSET-GKTFPDNARLIELARESGV
Mb2993c|M.bovis_AF2122/97 AAYCVADESIEAFRRFHAALFSKDIQPAEL-GKDFPDNARLIELAREAGV
Rv2969c|M.tuberculosis_H37Rv AAYCVADESIEAFRRFHAALFSKDIQPAEL-GKDFPDNARLIELAREAGV
MMAR_1747|M.marinum_M AAYCVADESIDAFRRFHTAMFSKDIQPSEV-GKTFPDNAKLIEIAREAGA
MUL_1990|M.ulcerans_Agy99 TAYCVADESIDAFRRFHTAMFSKDIQPSEV-GKTFPDNAKLIEIAREAGA
MAB_3269c|M.abscessus_ATCC_199 AAYCVADQSQELFLKFHSVLYDPSKQPDEVNSKTWHDDKWLIDQAKAVGA
TH_2711|M.thermoresistible__bu ALFAAAEPGSDAGATQVQAFVMQTYRLLSP-VGDNLDARGLAAVAGDVGL
: ..*: . : .: : . : * * *
Mflv_4202|M.gilvum_PYR-GCK TGGVPECINKGTYVDMVGGLARATEIKSTPTVRINGEEYQY---STPDAL
Mvan_2163|M.vanbaalenii_PYR-1 AGAVPECINKGTYVDMVAGLASATGVKSTPSVRINGEDYQY---STPEAL
MSMEG_2410|M.smegmatis_MC2_155 AGKVADCINNGRYVEMVKGMAAATGINATPTIRINGEDYSP---TTPDAL
MLBr_01667|M.leprae_Br4923 VGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDP---LTPEAL
MAV_3813|M.avium_104 VGKVPDCINSGKYIAKVTGEAAAAKIRATPTIKINGEDYDP---STPDAL
Mb2993c|M.bovis_AF2122/97 VGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEW---STPAAL
Rv2969c|M.tuberculosis_H37Rv VGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEW---STPAAL
MMAR_1747|M.marinum_M AGTVPDCINSGKYLDKVNGLAVAANVHATPTVKINGEEYEW---STPEAL
MUL_1990|M.ulcerans_Agy99 AGTVPDCINSGKYLDKVNGLAVAANVHATPTVKINGEEYEW---STPKAL
MAB_3269c|M.abscessus_ATCC_199 SDAVAKCIKDKKYINMVKELGPKLNIQATPTIRINGKDWEIGKGTTPDDL
TH_2711|M.thermoresistible__bu PDDVVDLIADN---APAVDVEAMDSYNTERFEELTGKRAYT---PMVFDL
. * . * . . : .:.* *
Mflv_4202|M.gilvum_PYR-GCK VAKIKEIVGDVPGLEAAPPAPAPQPAPAS
Mvan_2163|M.vanbaalenii_PYR-1 VTKIKEIVGDVPGLEAAPPAPAPQPAPAS
MSMEG_2410|M.smegmatis_MC2_155 VAKVKEIVGEVPGL---------------
MLBr_01667|M.leprae_Br4923 VAKIKAIVGAVPGIDVAVTATTT------
MAV_3813|M.avium_104 VGKIKEIVGDIPGLDGAVAPAAM------
Mb2993c|M.bovis_AF2122/97 VAKIKEIVGDVPGIDSAAATATS------
Rv2969c|M.tuberculosis_H37Rv VAKIKEIVGDVPGIDSAAATATS------
MMAR_1747|M.marinum_M VAKIKEIVGPIPGIDAVAANATS------
MUL_1990|M.ulcerans_Agy99 VAKIKEIVGPIPGIDAVAANATS------
MAB_3269c|M.abscessus_ATCC_199 IKAVTDITGPVPGLK--------------
TH_2711|M.thermoresistible__bu NARAEVDVDDPDWVADVIEGS--------
.. :