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VATKPKKNARYDLKAADRKRNLLVQIGLTAVVVIFAVTLVLYIVLSADDKPTAGESRAIRVESTSVIKKD GTDEPKAVLSMYEDFLCPHCGAFEQQFGPTISKLIDSGAIAADYYMVGILDRSQNQNYPSRAGGAAYCVA DESVDAFRRFHAALYAQQPSEAGSAYPDNARLIEVARQSGAAGAVPECINKGTYVDMVAGLASATGVKST PSVRINGEDYQYSTPEALVTKIKEIVGDVPGLEAAPPAPAPQPAPAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2163 | - | - | 100% (257) | hypothetical protein Mvan_2163 |
| M. vanbaalenii PYR-1 | Mvan_5558 | - | 4e-07 | 23.81% (252) | DSBA oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2993c | - | 3e-84 | 60.64% (249) | hypothetical protein Mb2993c |
| M. gilvum PYR-GCK | Mflv_4202 | - | 1e-133 | 89.11% (257) | hypothetical protein Mflv_4202 |
| M. tuberculosis H37Rv | Rv2969c | - | 3e-84 | 60.64% (249) | hypothetical protein Rv2969c |
| M. leprae Br4923 | MLBr_01667 | - | 2e-71 | 51.76% (255) | hypothetical protein MLBr_01667 |
| M. abscessus ATCC 19977 | MAB_3269c | - | 1e-58 | 47.45% (255) | hypothetical protein MAB_3269c |
| M. marinum M | MMAR_1747 | - | 2e-80 | 58.47% (248) | hypothetical protein MMAR_1747 |
| M. avium 104 | MAV_3813 | - | 2e-80 | 61.57% (255) | hypothetical protein MAV_3813 |
| M. smegmatis MC2 155 | MSMEG_2410 | - | 1e-95 | 70.54% (241) | putative serine-threonine protein kinase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1990 | - | 9e-80 | 57.66% (248) | hypothetical protein MUL_1990 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2163|M.vanbaalenii_PYR-1 ------MATKPKKNARYDLKAADR-KRNLLVQIGLTAVVVIFAVTLVLYI
Mflv_4202|M.gilvum_PYR-GCK ------MASKPKKNARYDLKAADR-KRNLLIQIGLTAVVVIFAVALVLYI
MSMEG_2410|M.smegmatis_MC2_155 -------MAKPKKTAKYDLKAADR-KRNLLVQIGLTAVVVLFAVALVLYI
MLBr_01667|M.leprae_Br4923 MRISEPVADNRKRLQRFDLKSVDG-RSGRAVVIAGTVIVAIFAVVVVFAV
MAV_3813|M.avium_104 ------MADNPKRPPRFDMKSASGGKSGRLVQIGGTAFVVIFAVALVFYI
Mb2993c|M.bovis_AF2122/97 ------MADKSKRPPRFDLKSADG-SFGRLVQIGGTTIVVVFAVVLVFYI
Rv2969c|M.tuberculosis_H37Rv ------MADKSKRPPRFDLKSADG-SFGRLVQIGGTTIVVVFAVVLVFYI
MMAR_1747|M.marinum_M ------MADKNKRPPRIDLNSPDG-KFGRLIQIGGTAFVVFFAVALVFYI
MUL_1990|M.ulcerans_Agy99 ------MADKNKRPTRIDLNSPDG-KFGRLIQIGGTAFVVFFAVALVFYI
MAB_3269c|M.abscessus_ATCC_199 -------MAKPKQPPSYDLKKAEQ-RRSQLIQIGLTAIVVLFAVGLVGFI
: *: *:: . . : *. *..*..*** :* :
Mvan_2163|M.vanbaalenii_PYR-1 VLSADDKP-----TAGESRAIRVES---TSVIKKDGTDEPKAVLSMYEDF
Mflv_4202|M.gilvum_PYR-GCK VGSADDKP-----TAGESRGIRVES---TSVIKKEGTDEPKAVVSMYEDF
MSMEG_2410|M.smegmatis_MC2_155 VMNGEKNP-----DAGAGKAIRVAS---SDVVTDEGSSDPKVVLGLYEDF
MLBr_01667|M.leprae_Br4923 MKSQHAKQDGAAPLTGSGDTVRVTS---SKLVTQPGTHDPKVVMSFYEDF
MAV_3813|M.avium_104 VTSHHKK----AGPTGAGDTVRVTS---SKLITQPGSSNPKAVVTLYEDF
Mb2993c|M.bovis_AF2122/97 VTSRDDKKDG---VAGPGDAVRVTS---SKLVTQPGTSNPKAVVSFYEDF
Rv2969c|M.tuberculosis_H37Rv VTSRDDKKDG---VAGPGDAVRVTS---SKLVTQPGTSNPKAVVSFYEDF
MMAR_1747|M.marinum_M VTSHQKKGGG---AAGPDDSVRVTS---SKLVTQPGTQDPKVVMTFYEDF
MUL_1990|M.ulcerans_Agy99 VTSHQKKGGG---AAGPDDSVRVTS---SKLVTQPGTQDPKVVMTFYEDF
MAB_3269c|M.abscessus_ATCC_199 VLSNKKDEGPPAPPAGEVKAIQVVTPGPAKLITKEGTTEPKVVLTLIEDP
: . . . :* ::* : :.::.. *: :**.*: : **
Mvan_2163|M.vanbaalenii_PYR-1 LCPHCGAFEQQFGPTISKLIDSGAIAADYYMVGILDRSQNQ-NYPSRAGG
Mflv_4202|M.gilvum_PYR-GCK LCPHCGAFEQQFGPTINKLVDAGAIAADYYMVGILDRPQNQ-NYPARAGG
MSMEG_2410|M.smegmatis_MC2_155 LCPACGNFERSFGPTISKLIDSGAIAADYYMVGILDRAGN--GYSSRAGG
MLBr_01667|M.leprae_Br4923 LCPGCGDFERNFGPTVSKLIDIGAIAADYSVVSILDHPRNH-NYPSRAGA
MAV_3813|M.avium_104 LCPACGNFERTFGPTVSKLIDLGAIAADYSMVSILDSPRNQ-NYSSRAGA
Mb2993c|M.bovis_AF2122/97 LCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQ-HYSSRAAA
Rv2969c|M.tuberculosis_H37Rv LCPACGIFERGFGPTVSKLVDIGAVAADYTMVAILDSASNQ-HYSSRAAA
MMAR_1747|M.marinum_M LCPACGMFERAFGPTVSRLVDIGAVAADYTMVDILSSPRNQ-NYSARAAA
MUL_1990|M.ulcerans_Agy99 LCPACGMFERAFGPTVSRLVDIGAVAADYTMVDILSSPRNQ-NYSARAAA
MAB_3269c|M.abscessus_ATCC_199 ICPACAMFEQEFGPTVKKLIDTGAVRADYDMVGILDVPRLKRDYSSRASA
:** *. **: ****:.:*:* **: *** :* **. . *.:**..
Mvan_2163|M.vanbaalenii_PYR-1 AAYCVADESVDAFRRFHAALYA--QQPSEA-GSAYPDNARLIEVARQSGA
Mflv_4202|M.gilvum_PYR-GCK AAYCVADESIDAFKRFHAALYA--QQPGET-GSTYPDNARLIEIARQSGA
MSMEG_2410|M.smegmatis_MC2_155 AGYCVADESTDAFRRFHTALYTPELQPQEN-SGIYPDNARLIELARQAGA
MLBr_01667|M.leprae_Br4923 ASLCVADESMDAYRRFRAALYSRSFQPSEL-ASSFPENAKLIEIAREAGV
MAV_3813|M.avium_104 AALCVADESLDAFRRFHTALFSTAIQPSET-GKTFPDNARLIELARESGV
Mb2993c|M.bovis_AF2122/97 AAYCVADESIEAFRRFHAALFSKDIQPAEL-GKDFPDNARLIELAREAGV
Rv2969c|M.tuberculosis_H37Rv AAYCVADESIEAFRRFHAALFSKDIQPAEL-GKDFPDNARLIELAREAGV
MMAR_1747|M.marinum_M AAYCVADESIDAFRRFHTAMFSKDIQPSEV-GKTFPDNAKLIEIAREAGA
MUL_1990|M.ulcerans_Agy99 TAYCVADESIDAFRRFHTAMFSKDIQPSEV-GKTFPDNAKLIEIAREAGA
MAB_3269c|M.abscessus_ATCC_199 AAYCVADQSQELFLKFHSVLYDPSKQPDEVNSKTWHDDKWLIDQAKAVGA
:. ****:* : : :*::.:: ** * . : :: **: *: *.
Mvan_2163|M.vanbaalenii_PYR-1 AGAVPECINKGTYVDMVAGLASATGVKSTPSVRINGEDYQY---STPEAL
Mflv_4202|M.gilvum_PYR-GCK TGGVPECINKGTYVDMVGGLARATEIKSTPTVRINGEEYQY---STPDAL
MSMEG_2410|M.smegmatis_MC2_155 AGKVADCINNGRYVEMVKGMAAATGINATPTIRINGEDYSP---TTPDAL
MLBr_01667|M.leprae_Br4923 VGKVPDCINSGKYLAKVTAEAALAKISATPTIKINGDEYDP---LTPEAL
MAV_3813|M.avium_104 VGKVPDCINSGKYIAKVTGEAAAAKIRATPTIKINGEDYDP---STPDAL
Mb2993c|M.bovis_AF2122/97 VGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEW---STPAAL
Rv2969c|M.tuberculosis_H37Rv VGKVPDCINSGKYIEKVDGLAAAVNVHATPTVRVNGTEYEW---STPAAL
MMAR_1747|M.marinum_M AGTVPDCINSGKYLDKVNGLAVAANVHATPTVKINGEEYEW---STPEAL
MUL_1990|M.ulcerans_Agy99 AGTVPDCINSGKYLDKVNGLAVAANVHATPTVKINGEEYEW---STPKAL
MAB_3269c|M.abscessus_ATCC_199 SDAVAKCIKDKKYINMVKELGPKLNIQATPTIRINGKDWEIGKGTTPDDL
. *..**:. *: * . : :**::::** ::. ** *
Mvan_2163|M.vanbaalenii_PYR-1 VTKIKEIVGDVPGLEAAPPAPAPQPAPAS
Mflv_4202|M.gilvum_PYR-GCK VAKIKEIVGDVPGLEAAPPAPAPQPAPAS
MSMEG_2410|M.smegmatis_MC2_155 VAKVKEIVGEVPGL---------------
MLBr_01667|M.leprae_Br4923 VAKIKAIVGAVPGIDVAVTATTT------
MAV_3813|M.avium_104 VGKIKEIVGDIPGLDGAVAPAAM------
Mb2993c|M.bovis_AF2122/97 VAKIKEIVGDVPGIDSAAATATS------
Rv2969c|M.tuberculosis_H37Rv VAKIKEIVGDVPGIDSAAATATS------
MMAR_1747|M.marinum_M VAKIKEIVGPIPGIDAVAANATS------
MUL_1990|M.ulcerans_Agy99 VAKIKEIVGPIPGIDAVAANATS------
MAB_3269c|M.abscessus_ATCC_199 IKAVTDITGPVPGLK--------------
: :. *.* :**: