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MHQLIAQIPLTDGWFPVVVQLIGALLLGAAVGWRTRRWRLRILPALVAAAAVLAGVMYRYIDSIGVAGNA GPPRLWVWIALTVLACGVLVLGWMSARWWRRIVSVAAVGACLLACGLTLNMWVGYFPTGYAMWNQLTSGP LPGQTDRLTVTKMQLAHFRPAGGVLVPVTIEAVSGFSHREELVYLPPAWFASSPPPELPAVMMIGSQLNT PADWLRAGNVQPVIDRFAAEHGGMAPVFVFVDATGSFANDTECVNGVRGNAADHLVKDVVPYLVSNFGVR PDRDGWGIAGWSMGGTCAVDLTLMHPDVFRSFVDIAGDLRPNAGDKAQTISRLWGGDVASWAAYDPVTIM GRHGPYTGPSADVTAWFEVPAAQRGAGPDPANPEGQDVAAVTLCDAARAVSIDCSVITEPGRHDWVFANT AFARALPWLAGQLHTPGVAAVPLPASTLGQQPTNVRAAPR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2314 | - | - | 100% (460) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_1034 | - | 0.0 | 100.00% (460) | putative esterase family protein |
| M. smegmatis MC2 155 | MSMEG_3797 | - | e-141 | 56.82% (440) | putative esterase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 1e-145 | 54.62% (465) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 1e-146 | 56.85% (445) | putative esterase |
| M. tuberculosis H37Rv | Rv1639c | - | 1e-145 | 54.62% (465) | hypothetical protein Rv1639c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1022 | - | 1e-139 | 52.38% (462) | hypothetical protein MAB_1022 |
| M. marinum M | MMAR_2446 | - | 1e-144 | 55.82% (455) | hypothetical protein MMAR_2446 |
| M. avium 104 | MAV_3129 | - | 1e-148 | 56.44% (450) | putative esterase family protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1625 | - | 1e-142 | 55.60% (455) | hypothetical protein MUL_1625 |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | 1e-146 | 57.05% (440) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1666c|M.bovis_AF2122/97 MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Rv1639c|M.tuberculosis_H37Rv MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MMAR_2446|M.marinum_M ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99 MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
MAV_3129|M.avium_104 ------------------------------MPMTVQVLAGVVLTLAVGWR
Mflv_3545|M.gilvum_PYR-GCK -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------MHGWLPVAVQILAVVAVVTAIGRR
MSMEG_2314|M.smegmatis_MC2_155 ----------------MHQLIAQIPLTDGWFPVVVQLIGALLLGAAVGWR
MAB_1022|M.abscessus_ATCC_1997 ----------------MRHYIGQLSLIHGWLPMLAQVGTAAVLSYAVYRR
.* .*: : * *
Mb1666c|M.bovis_AF2122/97 SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
Rv1639c|M.tuberculosis_H37Rv SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLANE--RPPSTLWIWVALT
MMAR_2446|M.marinum_M S----RRRLPAAVIFGAIAAWATRWYLG--TLANE--PVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99 S----RRRLPAAVIFGAIAAWVTRWYLG--TLANE--PVPAALWVWVGLT
MAV_3129|M.avium_104 SRRWRTVWVPVAALAGAAVAYLTHWYIVDRGLSDE--PAPAALWLWVMLT
Mflv_3545|M.gilvum_PYR-GCK TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
Mvan_3331|M.vanbaalenii_PYR-1 TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
MSMEG_2314|M.smegmatis_MC2_155 TRRWRLRILPALVAAAAVLAGVMYRYIDSIGVAGN--AGPPRLWVWIALT
MAB_1022|M.abscessus_ATCC_1997 SR---LMPVIAGLAMGVVLAAVAYWYLDALGVAGE--PAPPWLWLWIAGI
: : . * *: ::.: * **:*:
Mb1666c|M.bovis_AF2122/97 GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Rv1639c|M.tuberculosis_H37Rv GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MMAR_2446|M.marinum_M AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99 AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
MAV_3129|M.avium_104 GTAVAVLVLGWRTARRWRRGAAVLAVPLCLLSAALVLNLWVGYFPTVQSA
Mflv_3545|M.gilvum_PYR-GCK GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
Mvan_3331|M.vanbaalenii_PYR-1 GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
MSMEG_2314|M.smegmatis_MC2_155 VLACGVLVLGWMSARWWRRIVSVAAVGACLLACGLTLNMWVGYFPTGYAM
MAB_1022|M.abscessus_ATCC_1997 GLSAGLTGADWRGVRWWRRSLTVLAIPLCVICAGLSINVWIGYLPTVHSA
: : .* .* ** : *: * :.. * :*:*:**:** :
Mb1666c|M.bovis_AF2122/97 WNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASHFKHRGE
Rv1639c|M.tuberculosis_H37Rv WNQLTSGPLPDQADQAAVAALAHSGVRPSHGTLLPVVIPSDASHFKHRGE
MMAR_2446|M.marinum_M WNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASHFKHRGE
MUL_1625|M.ulcerans_Agy99 WNQLSSGPLPDQADPAAVVAMAGKGVRPAHGSMVPVAIPSNASHFKHRGE
MAV_3129|M.avium_104 WSQLTSGPLPDQTDQATVTAMAASRIRPPHGTVVPVAIPSDGSHFKHRGE
Mflv_3545|M.gilvum_PYR-GCK WNQLTAGPVPDQTDQVVVAALQKQHAVPIKGSVVPVQIPSTASGFTHRQE
Mvan_3331|M.vanbaalenii_PYR-1 WNQLTAGPLPDQTDAVTVAAMQKQHAMPVKGSLVAVDIPDTASGFRHRQE
MSMEG_2314|M.smegmatis_MC2_155 WNQLTSGPLPGQTDRLTVTKMQLAHFRPAGGVLVPVTIEA-VSGFSHREE
MAB_1022|M.abscessus_ATCC_1997 WARLVLAPVPGEVDRGTVLAMQIAGVQPPSGVVTPVTIPADASGFRHRTE
* :* .*:*.:.* .* : * * : .* * * * ** *
Mb1666c|M.bovis_AF2122/97 LVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKTLD
Rv1639c|M.tuberculosis_H37Rv LVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKTLD
MMAR_2446|M.marinum_M LVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRTID
MUL_1625|M.ulcerans_Agy99 LVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRTID
MAV_3129|M.avium_104 LVYLPPEWFA------TTPPPALPTVMMIGGQFNTPADWTRAGNAVKTID
Mflv_3545|M.gilvum_PYR-GCK FVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKILD
Mvan_3331|M.vanbaalenii_PYR-1 WVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAARTLD
MSMEG_2314|M.smegmatis_MC2_155 LVYLPPAWFA------SSPPPELPAVMMIGSQLNTPADWLRAGNVQPVID
MAB_1022|M.abscessus_ATCC_1997 LVYLPPAWFG------RNPAPRLPAVLMIGSALNTPADWIWAGHATQAAD
**:** *: *.* **.*:***. :****** ** . *
Mb1666c|M.bovis_AF2122/97 DFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMVS
Rv1639c|M.tuberculosis_H37Rv DFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMVS
MMAR_2446|M.marinum_M DFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYMIS
MUL_1625|M.ulcerans_Agy99 DFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYMIS
MAV_3129|M.avium_104 DFAAAHHGQAPVLVFVDSGGAFNNDTECVNGVRGNAADHLTKDVVPFMIS
Mflv_3545|M.gilvum_PYR-GCK EFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYLKS
Mvan_3331|M.vanbaalenii_PYR-1 AFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYMKS
MSMEG_2314|M.smegmatis_MC2_155 RFAAEHGGMAPVFVFVDATGSFANDTECVNGVRGNAADHLVKDVVPYLVS
MAB_1022|M.abscessus_ATCC_1997 DFAAGHGGYAPVLVFADATGAFNNDTECVNGRRGNAADHLVNDVVPYVTS
** * * *** **.*. *:* **** *** ***:****.:****:: *
Mb1666c|M.bovis_AF2122/97 KFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNAGN
Rv1639c|M.tuberculosis_H37Rv KFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNAGN
MMAR_2446|M.marinum_M AFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNAGN
MUL_1625|M.ulcerans_Agy99 AFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNAGN
MAV_3129|M.avium_104 AFGVSPHRSNWGVAGWSMGGTCAVDLTVMHPELFSAFVDVAGDFFPNAGN
Mflv_3545|M.gilvum_PYR-GCK QYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNAGT
Mvan_3331|M.vanbaalenii_PYR-1 HFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNAGT
MSMEG_2314|M.smegmatis_MC2_155 NFGVRPDRDGWGIAGWSMGGTCAVDLTLMHPDVFRSFVDIAGDLRPNAGD
MAB_1022|M.abscessus_ATCC_1997 NFRVGDDRSQWGVAGWSMGGTCALDLTVMHPETFSAFVDIAGDASPNTGD
: * **:.*********:***:*** * :***:*** **:*
Mb1666c|M.bovis_AF2122/97 KTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTG----LSGWFAISSP-GP
Rv1639c|M.tuberculosis_H37Rv KTQTIVRLFGGNEDAWSAFDPTTVITRHGSYTG----LSGWFAISSP-GP
MMAR_2446|M.marinum_M KAETITRLFGGNADAWAAFDPTTVINRHGQYTG----ISGWFSISVPAGP
MUL_1625|M.ulcerans_Agy99 KAETITRLFGGNADAWAAFDPTTVINRHGQYTG----ISGWFSISVPAGP
MAV_3129|M.avium_104 KAQTIARLFGGNADAWAAFDPTTVINRHGPYRD----VAGWFAISSD-GP
Mflv_3545|M.gilvum_PYR-GCK RNETVQRLFGGDSAAYAAFDPTAVMERHGPYRG----VEGWFAVN-----
Mvan_3331|M.vanbaalenii_PYR-1 QAETVDRLFGGDTAAYTSFDPTAVMTRHGPYRG----VAGWFDVNGA---
MSMEG_2314|M.smegmatis_MC2_155 KAQTISRLWGGDVASWAAYDPVTIMGRHGPYTGPSADVTAWFEVPAA---
MAB_1022|M.abscessus_ATCC_1997 QKHTIATLFGGDEAAWSRFDPATVINHHGRYGS----LAGWFDIPGG---
: .*: *:**: ::: :**.::: :** * . : .** :
Mb1666c|M.bovis_AF2122/97 PSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVV
Rv1639c|M.tuberculosis_H37Rv PSP--DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVV
MMAR_2446|M.marinum_M GAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVV
MUL_1625|M.ulcerans_Agy99 GAPR-DVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVV
MAV_3129|M.avium_104 PAPRRDIQLSDSGAIRLAAREAAANPGNQTAAAYSLCALGRANGIDCAVV
Mflv_3545|M.gilvum_PYR-GCK ------------------AVPGAATPNEQAVSAASLCGVGSRSGIACAVV
Mvan_3331|M.vanbaalenii_PYR-1 -----------------VAVSATAQPNDQAVAASSLCATGGRSGIDCAVV
MSMEG_2314|M.smegmatis_MC2_155 ---------------QRGAGPDPANPEGQDVAAVTLCDAARAVSIDCSVI
MAB_1022|M.abscessus_ATCC_1997 -MKHRLLTAAGIGSVSDGPHDGIANPEGQDIAANALCGLASAHGIRCAVS
* * * :* :** . .* *:*
Mb1666c|M.bovis_AF2122/97 PQPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIA
Rv1639c|M.tuberculosis_H37Rv PQPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT------QQIA
MMAR_2446|M.marinum_M PQPGRHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTAS---PATQVV
MUL_1625|M.ulcerans_Agy99 PQPGRHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTAS---PATQEV
MAV_3129|M.avium_104 PQPGRHDWPFADRAFAAALPWLAGALGTPGIPRTPLPATSSPAVGAPLVV
Mflv_3545|M.gilvum_PYR-GCK SRPGNHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVH---------
Mvan_3331|M.vanbaalenii_PYR-1 SQPGNHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVS---------
MSMEG_2314|M.smegmatis_MC2_155 TEPGRHDWVFANTAFARALPWLAGQLHTPGVAAVPLPASTLGQ-QPTNVR
MAB_1022|M.abscessus_ATCC_1997 AQPGRHDWPFAAQAFDAALPWLAGRLGVPQAARIPLPGLTPE--PSTSVA
..**.*** ** .* ******. : .* . :*
Mb1666c|M.bovis_AF2122/97 GTGR------
Rv1639c|M.tuberculosis_H37Rv GTGR------
MMAR_2446|M.marinum_M PAGR------
MUL_1625|M.ulcerans_Agy99 PAGR------
MAV_3129|M.avium_104 PAERSNTGKR
Mflv_3545|M.gilvum_PYR-GCK --G-------
Mvan_3331|M.vanbaalenii_PYR-1 --G-------
MSMEG_2314|M.smegmatis_MC2_155 AAPR------
MAB_1022|M.abscessus_ATCC_1997 SSVRAAGS--