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NVGRDTGGDTKRQKQSGEQFILRADRVTKRFSVKNNHNDVLSECSVDIREGEFVSLLGPSGCGKSTLLNM LAGFDLPDSGGVEFQGEPINGPSPQRVMCFQDSLQALLPWRTVQANVEFALSLAHVPRSDWPARVDELLT MVGLDRHRDSIPPQLSGGMRQKLQLARALSVDPAVLLMDEPFGALDAITREVMQRELLRIWAGSGKTVVF VTHDVGEAVLLSDTVYVMSTGPRAKIKHRFDIPADRPRSTTDPELSTLIDTIGRSLGSAAHA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2102 | - | - | 100% (273) | nitrate transport ATP-binding protein NrtD |
| M. smegmatis MC2 155 | MSMEG_1160 | - | 2e-53 | 46.26% (227) | ABC-type nitrate/sulfonate/bicarbonate transport system ATPase |
| M. smegmatis MC2 155 | MSMEG_2502 | - | 4e-51 | 46.98% (232) | transporter ATPase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 5e-36 | 41.01% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0722 | - | 3e-42 | 40.08% (242) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2397c | cysA1 | 5e-36 | 41.01% (217) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. leprae Br4923 | MLBr_01089 | - | 2e-33 | 39.70% (199) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_2243 | - | 3e-44 | 45.89% (207) | putative nitrate ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_0034 | proV_1 | 1e-38 | 40.89% (225) | osmoprotectant (glycine |
| M. avium 104 | MAV_3398 | - | 4e-47 | 46.82% (220) | ABC transporter ATP-binding protein |
| M. thermoresistible (build 8) | TH_4520 | - | 1e-36 | 39.41% (236) | PUTATIVE osmoprotectant (glycine |
| M. ulcerans Agy99 | MUL_0033 | proV_1 | 8e-37 | 39.56% (225) | osmoprotectant (glycine |
| M. vanbaalenii PYR-1 | Mvan_0123 | - | 9e-41 | 38.28% (256) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 ------------------MTYAIVVADATKRYGDF----VALDHVDFVVP
Rv2397c|M.tuberculosis_H37Rv ------------------MTYAIVVADATKRYGDF----VALDHVDFVVP
MAB_2243|M.abscessus_ATCC_1997 MTR----------------ASALVLDEVRLGYGGR----TVVDRLSLTVQ
MAV_3398|M.avium_104 MT-----------------AMRLELDRVRLSYNGP----AVINELSLVVR
MSMEG_2102|M.smegmatis_MC2_155 MNVGRDTGGDTKRQKQSGEQFILRADRVTKRFSVKNNHNDVLSECSVDIR
Mflv_0722|M.gilvum_PYR-GCK MSSQSDTEPVAPQRR----SGAIQIRSVSHRYGQGRDEVTALGPVDLTVE
Mvan_0123|M.vanbaalenii_PYR-1 MPSTND--------------GAIRIDSVSHHYGSGGAEVTALGPVDLTVD
MMAR_0034|M.marinum_M MPEAASADQPTTSDAPQSSGLRILLDGVTKRYGVRST--PAVDNVTLEIG
MUL_0033|M.ulcerans_Agy99 MPEAASADQPTTSDAPQSSGLRILLDGVTKRYGVRST--PAVDNVTLEIG
TH_4520|M.thermoresistible__bu ------VSEP-TSDLQSGGGARILLDGVTKRYDPKSP--PAVDNITMEIP
MLBr_01089|M.leprae_Br4923 -------------------MAEIVLEHVNKNYPNG---ATAVHDLSITVA
: . : .: . :
Mb2419c|M.bovis_AF2122/97 TGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR--VPPQRR
Rv2397c|M.tuberculosis_H37Rv TGSLTALLGPSGSGKSTLLRTIAGLDQPDTGTITINGRDVTR--VPPQRR
MAB_2243|M.abscessus_ATCC_1997 PGEILVLTGPSGCGKSTVLRALAGLLKPDAGTIRADGETVVT---TSRDR
MAV_3398|M.avium_104 PGEILVLTGPSGCGKSTVLRALAGLLTPDGGRVLADGVPVTG---TSGDR
MSMEG_2102|M.smegmatis_MC2_155 EGEFVSLLGPSGCGKSTLLNMLAGFDLPDSGGVEFQGEPING---PSPQR
Mflv_0722|M.gilvum_PYR-GCK PGSFLVLVGASGCGKSTLLRLLAGFESPTDGSVDVEGVPPT----PGVTA
Mvan_0123|M.vanbaalenii_PYR-1 PGSFLVLVGASGCGKSTLLRLLAGFEEPSQGSVQVAGARPT----PGVTA
MMAR_0034|M.marinum_M AGEIVMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDDDVTRRNPDELRR
MUL_0033|M.ulcerans_Agy99 AGEIVMLVGPSGCGKTTTMKVINRLIEPTSGRIFIGDDDVTRRNPDELRR
TH_4520|M.thermoresistible__bu AGEIVMLVGPSGCGKTTTMKMINRLIEPTSGRIFIGDDDVTERDADELRR
MLBr_01089|M.leprae_Br4923 DGEFLILIGPSGCGKTTTLNMIAGLEDISSGELRIDGDRVNEK--APKDR
*.: * *.**.**:* :. : : * : .
Mb2419c|M.bovis_AF2122/97 GIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG
Rv2397c|M.tuberculosis_H37Rv GIGFVFQHYAAFKHLTVRDNVAFGLKIRKRPKAEIKAKVDNLLQVVGLSG
MAB_2243|M.abscessus_ATCC_1997 AMVFQD--NALLPWRTVRSNIELALKLGGIARQGRREAAQSWIDDVGLTG
MAV_3398|M.avium_104 AMVFQD--NALLPWRTVRSNIELALRLRGQPRAGRRAAAERWISELGLAG
MSMEG_2102|M.smegmatis_MC2_155 VMCFQDSLQALLPWRTVQANVEFALSLAHVPRSDWPARVDELLTMVGLDR
Mflv_0722|M.gilvum_PYR-GCK GVVFQQ--PRLFPWRTVGGNVELALKYAKVPRDKRSERRDELLERVGLGG
Mvan_0123|M.vanbaalenii_PYR-1 GVVFQQ--PRLFPWRTVGGNVDMALRYAKVPRDKRIERREELLGRVGLEG
MMAR_0034|M.marinum_M HIGYVVQGAGLFPHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVNLDP
MUL_0033|M.ulcerans_Agy99 HIGYVVQGAGVFLHLTVGDNIGIVPRLLKWDKNRVAARIDELLDLVNLDP
TH_4520|M.thermoresistible__bu HIGYVIQGAGLFPHYTVAENIAIVPRLLKWDRKRIAARVDELLDLVSLDP
MLBr_01089|M.leprae_Br4923 DIAMVFQSYALYPHMTVRQNIAFPLMLAKVKKAEIAQKVSETAQILDLTD
: ** *: : : . :.*
Mb2419c|M.bovis_AF2122/97 --FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELR
Rv2397c|M.tuberculosis_H37Rv --FQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAKVREELR
MAB_2243|M.abscessus_ATCC_1997 --FENYLPKSLSGGMRQRVQLARGLAGAPRAVMMDEPFGALDAQTRASMQ
MAV_3398|M.avium_104 --FGDYLPKSLSGGMRQRVQLARGLAGAPRAVMMDEPFGALDTRTRAAMQ
MSMEG_2102|M.smegmatis_MC2_155 --HRDSIPPQLSGGMRQKLQLARALSVDPAVLLMDEPFGALDAITREVMQ
Mflv_0722|M.gilvum_PYR-GCK --TAGRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
Mvan_0123|M.vanbaalenii_PYR-1 --TADRRIWEISGGQQQRVAIARALAAETPLFLLDEPFAALDALTRERLQ
MMAR_0034|M.marinum_M AQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
MUL_0033|M.ulcerans_Agy99 AQYRDRFPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
TH_4520|M.thermoresistible__bu DEYRDRYPRELSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRQRLQ
MLBr_01089|M.leprae_Br4923 --LLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTR
. .:*** :*:: :.*.: . .::***:. :*. * :
Mb2419c|M.bovis_AF2122/97 AWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK-GRIEQVGSPTDVY
Rv2397c|M.tuberculosis_H37Rv AWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHK-GRIEQVGSPTDVY
MAB_2243|M.abscessus_ATCC_1997 RLLIDTWRSHPTTVVFVTHDVDEALLLGDRIVVLGR-AGQPLRAL-LDVP
MAV_3398|M.avium_104 RLLIDTWRTHPTTIVFVTHDVDEALALGDRIVVLGR-AGEPPRAS-VEVP
MSMEG_2102|M.smegmatis_MC2_155 RELLRIWAGSGKTVVFVTHDVGEAVLLSDTVYVMSTGPRAKIKHR-FDIP
Mflv_0722|M.gilvum_PYR-GCK EDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQIALDIPVDLP
Mvan_0123|M.vanbaalenii_PYR-1 EDVRQVSAESGRTTVFVTHSADEAAFLGSRIVVLTRRPGQVALDIPVDLP
MMAR_0034|M.marinum_M DELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPERIL
MUL_0033|M.ulcerans_Agy99 DELLRLQEELHKTIVFVTHDFGEAVKLGDRIAILTTGSKVVQYDTPERVL
TH_4520|M.thermoresistible__bu DELLRLQDELRKTIVFVTHDFDEAVKLGDRIAILQQGSKVVQYDTPEEIL
MLBr_01089|M.leprae_Br4923 GEIARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRS-GVVQQIGTPDELY
: * * ***. ** :.. : :: :
Mb2419c|M.bovis_AF2122/97 DAPANAFVMSFLGAVST-----------LNGSLVRPHDIRVGRTPNMAVA
Rv2397c|M.tuberculosis_H37Rv DAPANAFVMSFLGAVST-----------LNGSLVRPHDIRVGRTPNMAVA
MAB_2243|M.abscessus_ATCC_1997 ---EPRE---ADIDRSG-----------LRTEILAALNHTELVA------
MAV_3398|M.avium_104 ---EPR----SDRPHAE-----------LRAQIIDALNHAEAA-------
MSMEG_2102|M.smegmatis_MC2_155 ---ADRPRSTTDPELST-----------LIDTIGRSLGSAAHA-------
Mflv_0722|M.gilvum_PYR-GCK RTGVDPEELRRSPEYGE-----------LRAEVGAAVRRAAA--------
Mvan_0123|M.vanbaalenii_PYR-1 RTGVDPDELRRSPEYGQ-----------LRAEVGRAVKAAAA--------
MMAR_0034|M.marinum_M AEPANDFVRGFVGAGAT-----------LMQLSLTRVRDIDLHEAVVAQA
MUL_0033|M.ulcerans_Agy99 AEPANDFVRGFVGAGAT-----------LMQLSLTRVRDIDLHEAVVAQA
TH_4520|M.thermoresistible__bu TNPADDFVKGFVGHGAA-----------LKQLTLTRVRDVDLHDAVTARA
MLBr_01089|M.leprae_Br4923 ERPVNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHP
*
Mb2419c|M.bovis_AF2122/97 AADGTAGSTGVLRAVVDRVVVLGFEVRVELTS------------------
Rv2397c|M.tuberculosis_H37Rv AADGTAGSTGVLRAVVDRVVVLGFEVRVELTS------------------
MAB_2243|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3398|M.avium_104 --------------------------------------------------
MSMEG_2102|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0034|M.marinum_M GGDPAEAVELAGSLDREHAIVLDRQNRPLRWLPLEELAKPQALAQVTRDD
MUL_0033|M.ulcerans_Agy99 GGDPAEAVELAGSLDRAHAIVLDRQNRPLRWLPLEELAKPQALAQVTRDD
TH_4520|M.thermoresistible__bu GGDPDEAIHAARAADREHVIVLDAQNRPMRWMSLAELARPGALIRVSRDE
MLBr_01089|M.leprae_Br4923 VPDRVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFT
Mb2419c|M.bovis_AF2122/97 -------AATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSG
Rv2397c|M.tuberculosis_H37Rv -------AATGGAFTAQITRGDAEALALREGDTVYVRATRVPPIAGGVSG
MAB_2243|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_3398|M.avium_104 --------------------------------------------------
MSMEG_2102|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_0722|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0123|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_0034|M.marinum_M DLECVNLASTLNDALDEMLTSSHGVVVVTGRRNTYQGVIRVETIMEAIAD
MUL_0033|M.ulcerans_Agy99 DLECVNLASTLNDALDEMLTSAHGVVVVTGRRNTYQGVIRVETIMEAIAD
TH_4520|M.thermoresistible__bu NLECVTLASTLTDALDDMLTSSHGVVVVTGRRNTYQGVIRLETIMDAIAD
MLBr_01089|M.leprae_Br4923 TTGCDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKI
Mb2419c|M.bovis_AF2122/97 VDDAGVERVKVTST-----
Rv2397c|M.tuberculosis_H37Rv VDDAGVERVKVTST-----
MAB_2243|M.abscessus_ATCC_1997 -------------------
MAV_3398|M.avium_104 -------------------
MSMEG_2102|M.smegmatis_MC2_155 -------------------
Mflv_0722|M.gilvum_PYR-GCK -------------------
Mvan_0123|M.vanbaalenii_PYR-1 -------------------
MMAR_0034|M.marinum_M IRGAANSEEPDT-------
MUL_0033|M.ulcerans_Agy99 IRGAANSEEPDT-------
TH_4520|M.thermoresistible__bu ARGTAGSQGAGAP------
MLBr_01089|M.leprae_Br4923 AVFDADSGVNLTVSAPTDA