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LGRARDYDIIIGDLQTGPLNAITDVDGVRVGHTTLVSGSGPRNPGNGPVRTGVTVVIPREEPWNRPLFAA PHRLNGNGELTGQHWVAESGQLTSYIGLTNTHSVGVVRDALIAHEKSVRGDEFFFSLPVVGETCDGILND LNGFHVRPEHVAEAIENATDGPVEEGAVGGGTGMVAHGYKGGIGTSSRVVGDHTVGVLVQANHGARERLM IDGVPVGRLLPPPPTPVIMPGQPPEGTGSIIVLVATDAPLIPTQCARLAQRAALGIARTGGAGENGSGDI AFCFATGNGFVGDFAAEPGPDVAQINMLANRLIDGLFYATVEATEEAIINAMFAAETMEGPEGLVVHALP RDETAELVKRYRSMVVG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_2092 | - | - | 100% (367) | D-aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_1507 | - | e-108 | 55.62% (356) | D-aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_4908 | - | 7e-09 | 29.63% (189) | endo-type 6-aminohexanoate oligomer hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1368 | - | 9e-10 | 26.67% (360) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3141 | - | 7e-71 | 45.00% (360) | peptidase S58, DmpA |
| M. tuberculosis H37Rv | Rv1333 | - | 9e-10 | 26.67% (360) | hydrolase |
| M. leprae Br4923 | MLBr_01167 | - | 9e-14 | 27.61% (355) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_1477 | - | 5e-11 | 29.09% (361) | hypothetical protein MAB_1477 |
| M. marinum M | MMAR_4065 | dmpA | 5e-09 | 29.23% (195) | L-aminopeptidase/D-esterase DmpA |
| M. avium 104 | MAV_1553 | - | 1e-11 | 27.27% (363) | peptidase family protein T4 |
| M. thermoresistible (build 8) | TH_1833 | - | 1e-180 | 83.56% (365) | D-aminopeptidase |
| M. ulcerans Agy99 | MUL_3929 | dmpA | 4e-09 | 30.46% (197) | L-aminopeptidase/D-esterase DmpA |
| M. vanbaalenii PYR-1 | Mvan_3384 | - | 4e-71 | 43.96% (364) | peptidase S58, DmpA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1368|M.bovis_AF2122/97 -----------------------------------MNSITDVGGIRVGHY
Rv1333|M.tuberculosis_H37Rv -----------------------------------MNSITDVGGIRVGHY
MMAR_4065|M.marinum_M -----------------------------------MSSITDIGGIRVGHY
MUL_3929|M.ulcerans_Agy99 -----------------------------------MSSITDIGGIRVGHY
MAV_1553|M.avium_104 -----------------------------------MNAITDVGGIRVGHH
MLBr_01167|M.leprae_Br4923 ----------------------------MILMAAPMNSITDISGIQVGHY
MAB_1477|M.abscessus_ATCC_1997 -------------------------------MSLFSGAITDVPGILVGHH
MSMEG_2092|M.smegmatis_MC2_155 -----------------MGRARDYDIIIGDLQTGPLNAITDVDGVRVGHT
TH_1833|M.thermoresistible__bu -----------------VARARDYGATIGVLPTGPNNAITDVAGVRVGHT
Mflv_3141|M.gilvum_PYR-GCK MIHRVTGIDFATTTPDGTSRARGVGIPFQGTP-GPLNALTDVAGVEVGAT
Mvan_3384|M.vanbaalenii_PYR-1 MIHRVTATNLATHTPDGRPRARGAGIGFSGQP-GPLNALTDVAGVQIGVT
.::**: *: :*
Mb1368|M.bovis_AF2122/97 QRLDPDASLGAG---WACGVTVVLPP---PGTVGAVDCRGGAPGTRETDL
Rv1333|M.tuberculosis_H37Rv QRLDPDASLGAG---WACGVTVVLPP---PGTVGAVDCRGGAPGTRETDL
MMAR_4065|M.marinum_M QRLDPDASLGAG---WASGVTVVLAP---PGTVGAVDCRGGAPGTRETDL
MUL_3929|M.ulcerans_Agy99 QRLDPDASLGAG---WASGVTVVLAP---PGTVGAVDCRGGAPGTRETDL
MAV_1553|M.avium_104 QRLDPDASLGAG---WACGVTVVLTP---PGTVGAVDCRGGAPGTRETDL
MLBr_01167|M.leprae_Br4923 HRLDPDASLGAG---WACGVTVVLTP---PGTVGAVDCRGGVPGTRETDL
MAB_1477|M.abscessus_ATCC_1997 QRVDADASLGAG---WATGTTVVLAP---PGTTGAVDVRGGAPGTRESDL
MSMEG_2092|M.smegmatis_MC2_155 TLVSGSGPRNPGNGPVRTGVTVVIPR-EEPWNRPLFAAPHRLNGNGELTG
TH_1833|M.thermoresistible__bu TLIEGSGPRVTGQGPVRTGVTVVIPR-DEPWNHPLFAAAHRLNGNGELTG
Mflv_3141|M.gilvum_PYR-GCK TLIDGDGPLCVGAGPVRTGVTAILPRGRDGVGQPCAAGWYSLNGNGEMTG
Mvan_3384|M.vanbaalenii_PYR-1 TLIDGDGPLIVGQGPIRTGVTAILPRGRSGVGQPCAAGWYSLNGNGEMTG
:. ... * *.*.::. *. *
Mb1368|M.bovis_AF2122/97 LDPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIV
Rv1333|M.tuberculosis_H37Rv LDPANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIV
MMAR_4065|M.marinum_M LDPVNSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGAGVVPIV
MUL_3929|M.ulcerans_Agy99 LDPVNSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGTGVVPIV
MAV_1553|M.avium_104 LDPANTVRFVDAVLLAGGSAYGLAAADGVMRWLEEHDRGVAMDGGVVPIV
MLBr_01167|M.leprae_Br4923 LDPANSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIV
MAB_1477|M.abscessus_ATCC_1997 LDPANTVATVDAVVLTGGSAYGLAAADGVMRWLEERGRGVPLSGGTVPIV
MSMEG_2092|M.smegmatis_MC2_155 QHWVAESGQLTSYIGLTNTHSVGVVRDALIAHEKSVRG-DEFFFSLPVVG
TH_1833|M.thermoresistible__bu QHWVEESGQLTSYIGLTNTHSVGVVRDALIAHEKNARGADEFFFALPVVG
Mflv_3141|M.gilvum_PYR-GCK TTWIDEVGSFNLPVVLSNTHAVGACHTGVVQWANRVAPRLGRQWLLPVCA
Mvan_3384|M.vanbaalenii_PYR-1 TTWIDEVGSFNLPVVLSNTHAVGACHTGVVRWANRVAPRLARQWLLPVCA
. : .: . .:: :
Mb1368|M.bovis_AF2122/97 PGAVIFDLPVGGWNCRPTADFGYSACAAAGVD--------VAVGTVGVGV
Rv1333|M.tuberculosis_H37Rv PGAVIFDLPVGGWNCRPTADFGYSACAAAGVD--------VAVGTVGVGV
MMAR_4065|M.marinum_M PGAVIFDLPVGGWGQRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGV
MUL_3929|M.ulcerans_Agy99 PGAVIFDLPVGGWGQRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGV
MAV_1553|M.avium_104 PGAVIFDLPVGGWQCRPTAEFGYLACAAARDDD------APAVGTVGAGV
MLBr_01167|M.leprae_Br4923 PGAVIFDLSVGDFHCRPTAEFGYLACQAAYDAAVGGQDATVAVGTVGAGV
MAB_1477|M.abscessus_ATCC_1997 PAAVIFDLPVGAWKNRPDTEFGYRAAELADDAP--------EWGAVGAGA
MSMEG_2092|M.smegmatis_MC2_155 ETCDGILNDLNGFHVRP--EHVAEAIENATDGP-------VEEGAVGGGT
TH_1833|M.thermoresistible__bu ETCDGILNDINGFHVKP--EHVAAAIDAAADGP-------VPEGAVGGGT
Mflv_3141|M.gilvum_PYR-GCK ETWDGYLNDINGGHVRP--DHVEAALDAARGGP-------VAEGSVGGGT
Mvan_3384|M.vanbaalenii_PYR-1 ETWDGYLNDINGGHVRP--EHVEAALDAATAGP-------VAEGSVGGGT
:. :* :. * * *:** *.
Mb1368|M.bovis_AF2122/97 GARAGALKGGVGTASATLQ---SGVTVGVLAVVNAAGNVVDPATGLPWMA
Rv1333|M.tuberculosis_H37Rv GARAGALKGGVGTASATLQ---SGVTVGVLAVVNAAGNVVDPATGLPWMA
MMAR_4065|M.marinum_M GARAGVLKGGVGTASVKLP---SGVTVGAVVVVNSVGNVVDPATGLPWMA
MUL_3929|M.ulcerans_Agy99 GARAGVLKGGVGTASVKLP---SGVTVGAVVVVNSVGNVVDPATGLPWMA
MAV_1553|M.avium_104 GARAGALKGGVGTASRSLP---SGVTVGALAVVNSAGEVVDRATGLPWMT
MLBr_01167|M.leprae_Br4923 GARAGVLKGGVGTASITLE---SGPTVGAVVVVNSVGDVVDRATGLPWMT
MAB_1477|M.abscessus_ATCC_1997 GARAGTLKGGVGSASVNVG---DGIVVGALVVANPVGLVINPATGRPWTA
MSMEG_2092|M.smegmatis_MC2_155 GMVAHGYKGGIGTSSRVVG----DHTVGVLVQANHGARERLMIDGVPVG-
TH_1833|M.thermoresistible__bu GMIAHGYKGGIGTSSRVVG----DYTVGVLVQANHGARERLTIDGVPVG-
Mflv_3141|M.gilvum_PYR-GCK GMNCYDFKGGNGTASRIVPYGSRTYTVAAFVQANFGARAELTIAGRHVGP
Mvan_3384|M.vanbaalenii_PYR-1 GMNCYEFKGGNGTASRLVPYGRRTYTVAAFVQANFGSRAELTITGSHIGP
* . *** *::* : .*.... .* . *
Mb1368|M.bovis_AF2122/97 DLVGEFALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAAL
Rv1333|M.tuberculosis_H37Rv DLVGEFALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAAL
MMAR_4065|M.marinum_M ELSGEFGLTRPPADQLDELARLPSPLDPQNAPQDRPLNTTIAVVATDAAL
MUL_3929|M.ulcerans_Agy99 ELSGEFGLTRPPADQLDELARLPSPLDPQDAPQDRPLNTTIAVVATDAAL
MAV_1553|M.avium_104 DLVEQFGLRPPPVEQIEAFAALPSPSNPLDNP----LNTVIAVVATDAAL
MLBr_01167|M.leprae_Br4923 DLIDEFALRPPSPEQIAGFAQLKSPLSA--------LNTTIGVVATDATL
MAB_1477|M.abscessus_ATCC_1997 DILPELS--APPAAEIEKLRDLPDKSVS--------LNTTIGVVATNAAL
MSMEG_2092|M.smegmatis_MC2_155 RLLPPPPTP-------VIMPGQPPEGTG----------SIIVLVATDAPL
TH_1833|M.thermoresistible__bu RLLPEPPSP-------AAMPGRPPEGTG----------SIIVLVATDAPL
Mflv_3141|M.gilvum_PYR-GCK EMLDDNPLDGDWFA--RDLDGAPP-GAG----------SVIAVIATDAPL
Mvan_3384|M.vanbaalenii_PYR-1 QLMDDNPLDGDWFA--RDLAAAPPPGAG----------SVIAVVATDAPL
: : : * ::* :*.*
Mb1368|M.bovis_AF2122/97 SPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------A
Rv1333|M.tuberculosis_H37Rv SPAACRRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------A
MMAR_4065|M.marinum_M SPAGCQRVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------Q
MUL_3929|M.ulcerans_Agy99 SPAGCQRVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------Q
MAV_1553|M.avium_104 SAAACRRVAVAAHDGLARSIRPAHTPVDGDTVFVLATGAV---------E
MLBr_01167|M.leprae_Br4923 SPAACQRVAMAAQDGLARTIRPAHTALDGDTVFALATGAV---------E
MAB_1477|M.abscessus_ATCC_1997 SKAQCRRVAIAAHDGLARAIRPAHTPMDGDTLYVLATGTG---------E
MSMEG_2092|M.smegmatis_MC2_155 IPTQCARLAQRAALGIARTG-GAGENGSGDIAFCFATGNG--FVGDFAAE
TH_1833|M.thermoresistible__bu IPTQCARLAQRSALGIARTG-GAGENGSGDMAFCFTTGNT--FAGDFAAT
Mflv_3141|M.gilvum_PYR-GCK LPGQCRALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEASGLASAFPLG
Mvan_3384|M.vanbaalenii_PYR-1 LPGQCKALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEVPDLASTFPLG
* :* *:**: : .** ::*.
Mb1368|M.bovis_AF2122/97 VPPEAGVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR
Rv1333|M.tuberculosis_H37Rv VPPEAGVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR
MMAR_4065|M.marinum_M VPPDPAIPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR
MUL_3929|M.ulcerans_Agy99 VPPDPAIPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR
MAV_1553|M.avium_104 VPPEADTPAAFSPETRLATEVGAAAADCLAHAVLGGVLAADSVAGIPSYR
MLBr_01167|M.leprae_Br4923 ATATADVPVAMSPETGLITEVGAAADDCLARAVLVAVLAAESVAGIPTYC
MAB_1477|M.abscessus_ATCC_1997 GDADP-----------LTAAVGIAAADCVERAVVRAVVGAASVAGIPAYR
MSMEG_2092|M.smegmatis_MC2_155 P-GPD-VAQINMLANRLIDGLFYATVEATEEAIINAMFAAETMEGPEGLV
TH_1833|M.thermoresistible__bu A-GPD-VVEVRMLANRLIDRLFYAAIEATEEAIVNALFAAETMEGPEGLV
Mflv_3141|M.gilvum_PYR-GCK PPGEDELGTISFLPWGRMDTVYAAVVQSVEEAVLNALVVNTDMVGRDGHR
Mvan_3384|M.vanbaalenii_PYR-1 PVGDDELGSITFLPWGRMDDLYAAVVQCVEEAVLNALVVNTDMVGRDGHR
: *. :. .*:: .:. : *
Mb1368|M.bovis_AF2122/97 -DMFPGAFGS------------
Rv1333|M.tuberculosis_H37Rv -DMFPGAFGS------------
MMAR_4065|M.marinum_M -DVLPGALQTSGTESR------
MUL_3929|M.ulcerans_Agy99 -DVLPGALQTSGTESR------
MAV_1553|M.avium_104 -DVLPGALGR------------
MLBr_01167|M.leprae_Br4923 -GMFPGAFGTTIGGGNR-----
MAB_1477|M.abscessus_ATCC_1997 -DVLPGAFS-------------
MSMEG_2092|M.smegmatis_MC2_155 VHALPRDETAELVKRYRSMVVG
TH_1833|M.thermoresistible__bu VTALPREQTAELLRRYRQLR--
Mflv_3141|M.gilvum_PYR-GCK SPRLPLDRLTELLGGRP-----
Mvan_3384|M.vanbaalenii_PYR-1 SPRLPLDRLPALLSRRP-----
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