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VADSPRKRVRNLGVVVGEHPTGPYNAITDVAGVRVGHTTIQDGAAVNTGVTVVVPHDDIWGEPVFAGAHR LNGSGEMTGLEWIRESGELTTAIGLTNTHSAGVVRDALVDAQVAARGDGLYWSLPVVGETYDGLLNDING HHVRAEHVHAALAAASDGPVAEGNVGGGTGMICHGFKGGIGTASRVTDTAAGRYTVGVLVQANHGRRERL RVNGVPVGEVIGPEAVPLPEMPRAYEPGSGSIIVIVATDAPLLPHQCARLAQRSALAVGRLGGTGEQYSG DLMLAFSTGNRGIPPYAWDENVDTERPEIDVRMVAPQLMTRLFDLTIEATEEAILNVLVTAETLTGRDGR TAHALDHKLFRTALLLEDH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1507 | - | - | 100% (369) | D-aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_2092 | - | e-108 | 55.62% (356) | D-aminopeptidase |
| M. smegmatis MC2 155 | MSMEG_4908 | - | 2e-09 | 27.87% (348) | endo-type 6-aminohexanoate oligomer hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1368 | - | 3e-12 | 28.76% (299) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3141 | - | 1e-71 | 44.20% (362) | peptidase S58, DmpA |
| M. tuberculosis H37Rv | Rv1333 | - | 3e-12 | 28.76% (299) | hydrolase |
| M. leprae Br4923 | MLBr_01167 | - | 3e-10 | 28.67% (293) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_1477 | - | 1e-06 | 27.91% (301) | hypothetical protein MAB_1477 |
| M. marinum M | MMAR_4065 | dmpA | 3e-10 | 27.37% (358) | L-aminopeptidase/D-esterase DmpA |
| M. avium 104 | MAV_1553 | - | 2e-12 | 27.71% (350) | peptidase family protein T4 |
| M. thermoresistible (build 8) | TH_1833 | - | 1e-111 | 58.42% (368) | D-aminopeptidase |
| M. ulcerans Agy99 | MUL_3929 | dmpA | 2e-10 | 27.37% (358) | L-aminopeptidase/D-esterase DmpA |
| M. vanbaalenii PYR-1 | Mvan_3384 | - | 3e-70 | 43.48% (368) | peptidase S58, DmpA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1368|M.bovis_AF2122/97 -----------------------------------MNSITDVGGIRVGHY
Rv1333|M.tuberculosis_H37Rv -----------------------------------MNSITDVGGIRVGHY
MMAR_4065|M.marinum_M -----------------------------------MSSITDIGGIRVGHY
MUL_3929|M.ulcerans_Agy99 -----------------------------------MSSITDIGGIRVGHY
MAV_1553|M.avium_104 -----------------------------------MNAITDVGGIRVGHH
MLBr_01167|M.leprae_Br4923 ----------------------------MILMAAPMNSITDISGIQVGHY
MAB_1477|M.abscessus_ATCC_1997 -------------------------------MSLFSGAITDVPGILVGHH
MSMEG_1507|M.smegmatis_MC2_155 ------------MADSPRKRVRNLGVVVGEHPTGPYNAITDVAGVRVGHT
TH_1833|M.thermoresistible__bu -----------------VARARDYGATIGVLPTGPNNAITDVAGVRVGHT
Mflv_3141|M.gilvum_PYR-GCK MIHRVTGIDFATTTPDGTSRARGVGIPFQGTP-GPLNALTDVAGVEVGAT
Mvan_3384|M.vanbaalenii_PYR-1 MIHRVTATNLATHTPDGRPRARGAGIGFSGQP-GPLNALTDVAGVQIGVT
.::**: *: :*
Mb1368|M.bovis_AF2122/97 QRLDPDASLGAG---WACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDP
Rv1333|M.tuberculosis_H37Rv QRLDPDASLGAG---WACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDP
MMAR_4065|M.marinum_M QRLDPDASLGAG---WASGVTVVLAPPGTVGAVDCRGGAPGTRETDLLDP
MUL_3929|M.ulcerans_Agy99 QRLDPDASLGAG---WASGVTVVLAPPGTVGAVDCRGGAPGTRETDLLDP
MAV_1553|M.avium_104 QRLDPDASLGAG---WACGVTVVLTPPGTVGAVDCRGGAPGTRETDLLDP
MLBr_01167|M.leprae_Br4923 HRLDPDASLGAG---WACGVTVVLTPPGTVGAVDCRGGVPGTRETDLLDP
MAB_1477|M.abscessus_ATCC_1997 QRVDADASLGAG---WATGTTVVLAPPGTTGAVDVRGGAPGTRESDLLDP
MSMEG_1507|M.smegmatis_MC2_155 TIQDG--------AAVNTGVTVVVPHD-DIWGEPVFAGAHRLNGSGEMTG
TH_1833|M.thermoresistible__bu TLIEGSGPRVTGQGPVRTGVTVVIPRD-EPWNHPLFAAAHRLNGNGELTG
Mflv_3141|M.gilvum_PYR-GCK TLIDGDGPLCVGAGPVRTGVTAILPRGRDGVGQPCAAGWYSLNGNGEMTG
Mvan_3384|M.vanbaalenii_PYR-1 TLIDGDGPLIVGQGPIRTGVTAILPRGRSGVGQPCAAGWYSLNGNGEMTG
: *.*.::. .. . .. :
Mb1368|M.bovis_AF2122/97 ANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGA
Rv1333|M.tuberculosis_H37Rv ANSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGA
MMAR_4065|M.marinum_M VNSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGAGVVPIVPGA
MUL_3929|M.ulcerans_Agy99 VNSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGTGVVPIVPGA
MAV_1553|M.avium_104 ANTVRFVDAVLLAGGSAYGLAAADGVMRWLEEHDRGVAMDGGVVPIVPGA
MLBr_01167|M.leprae_Br4923 ANSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGA
MAB_1477|M.abscessus_ATCC_1997 ANTVATVDAVVLTGGSAYGLAAADGVMRWLEERGRGVPLSGGTVPIVPAA
MSMEG_1507|M.smegmatis_MC2_155 LEWIRESGELTTAIGLTNTHSAGVVRDALVDAQVAARG-DGLYWSLPVVG
TH_1833|M.thermoresistible__bu QHWVEESGQLTSYIGLTNTHSVGVVRDALIAHEKNARGADEFFFALPVVG
Mflv_3141|M.gilvum_PYR-GCK TTWIDEVGSFNLPVVLSNTHAVGACHTGVVQWANRVAPRLGRQWLLPVCA
Mvan_3384|M.vanbaalenii_PYR-1 TTWIDEVGSFNLPVVLSNTHAVGACHTGVVRWANRVAPRLARQWLLPVCA
: . . : :.. : : .
Mb1368|M.bovis_AF2122/97 VIFDLPVGGWN-CRPTADFGYSACAAAGVD--------VAVGTVGVGVGA
Rv1333|M.tuberculosis_H37Rv VIFDLPVGGWN-CRPTADFGYSACAAAGVD--------VAVGTVGVGVGA
MMAR_4065|M.marinum_M VIFDLPVGGWG-QRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGVGA
MUL_3929|M.ulcerans_Agy99 VIFDLPVGGWG-QRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGVGA
MAV_1553|M.avium_104 VIFDLPVGGWQ-CRPTAEFGYLACAAARDDD------APAVGTVGAGVGA
MLBr_01167|M.leprae_Br4923 VIFDLSVGDFH-CRPTAEFGYLACQAAYDAAVGGQDATVAVGTVGAGVGA
MAB_1477|M.abscessus_ATCC_1997 VIFDLPVGAWK-NRPDTEFGYRAAELADDAP--------EWGAVGAGAGA
MSMEG_1507|M.smegmatis_MC2_155 ETYDGLLNDINGHHVRAEHVHAALAAASDGP-------VAEGNVGGGTGM
TH_1833|M.thermoresistible__bu ETCDGILNDINGFHVKPEHVAAAIDAAADGP-------VPEGAVGGGTGM
Mflv_3141|M.gilvum_PYR-GCK ETWDGYLNDINGGHVRPDHVEAALDAARGGP-------VAEGSVGGGTGM
Mvan_3384|M.vanbaalenii_PYR-1 ETWDGYLNDINGGHVRPEHVEAALDAATAGP-------VAEGSVGGGTGM
* :. : .:. * * * ** *.*
Mb1368|M.bovis_AF2122/97 RAGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGE
Rv1333|M.tuberculosis_H37Rv RAGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGE
MMAR_4065|M.marinum_M RAGVLKGGVGTASVKLPSGVTVGAVVVVNSVGNVVDPATGLPWMAELSGE
MUL_3929|M.ulcerans_Agy99 RAGVLKGGVGTASVKLPSGVTVGAVVVVNSVGNVVDPATGLPWMAELSGE
MAV_1553|M.avium_104 RAGALKGGVGTASRSLPSGVTVGALAVVNSAGEVVDRATGLPWMTDLVEQ
MLBr_01167|M.leprae_Br4923 RAGVLKGGVGTASITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDE
MAB_1477|M.abscessus_ATCC_1997 RAGTLKGGVGSASVNVGDGIVVGALVVANPVGLVINPATGRPWTADILPE
MSMEG_1507|M.smegmatis_MC2_155 ICHGFKGGIGTASRVTDTA--AGRYTVGVLVQANHGRRERLRVNGVPVG-
TH_1833|M.thermoresistible__bu IAHGYKGGIGTSSRV------VGDYTVGVLVQANHGARERLTIDGVPVG-
Mflv_3141|M.gilvum_PYR-GCK NCYDFKGGNGTASRIVPYG--SRTYTVAAFVQANFGARAELTIAGRHVGP
Mvan_3384|M.vanbaalenii_PYR-1 NCYEFKGGNGTASRLVPYG--RRTYTVAAFVQANFGSRAELTITGSHIGP
. *** *::* .* . .
Mb1368|M.bovis_AF2122/97 FALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAALSPAAC
Rv1333|M.tuberculosis_H37Rv FALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAALSPAAC
MMAR_4065|M.marinum_M FGLTRPPADQLDELARLPSPLDPQNAPQDRPLNTTIAVVATDAALSPAGC
MUL_3929|M.ulcerans_Agy99 FGLTRPPADQLDELARLPSPLDPQDAPQDRPLNTTIAVVATDAALSPAGC
MAV_1553|M.avium_104 FGLRPPPVEQIEAFAALPSPSNPLDNP----LNTVIAVVATDAALSAAAC
MLBr_01167|M.leprae_Br4923 FALRPPSPEQIAGFAQLKSPLSA--------LNTTIGVVATDATLSPAAC
MAB_1477|M.abscessus_ATCC_1997 LS--APPAAEIEKLRDLPDKSVS--------LNTTIGVVATNAALSKAQC
MSMEG_1507|M.smegmatis_MC2_155 EVIGPEAVP----LPEMPRAYEP-------GSGSIIVIVATDAPLLPHQC
TH_1833|M.thermoresistible__bu RLL-PEPPS----PAAMPGRPPE-------GTGSIIVLVATDAPLIPTQC
Mflv_3141|M.gilvum_PYR-GCK EMLDDNPLDGDWFARDLDGAPP--------GAGSVIAVIATDAPLLPGQC
Mvan_3384|M.vanbaalenii_PYR-1 QLMDDNPLDGDWFARDLAAAPPP-------GAGSVIAVVATDAPLLPGQC
. : .: * ::* :*.* *
Mb1368|M.bovis_AF2122/97 RRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------AVPPEA
Rv1333|M.tuberculosis_H37Rv RRIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------AVPPEA
MMAR_4065|M.marinum_M QRVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------QVPPDP
MUL_3929|M.ulcerans_Agy99 QRVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------QVPPDP
MAV_1553|M.avium_104 RRVAVAAHDGLARSIRPAHTPVDGDTVFVLATGAV---------EVPPEA
MLBr_01167|M.leprae_Br4923 QRVAMAAQDGLARTIRPAHTALDGDTVFALATGAV---------EATATA
MAB_1477|M.abscessus_ATCC_1997 RRVAIAAHDGLARAIRPAHTPMDGDTLYVLATGTG---------EGDADP
MSMEG_1507|M.smegmatis_MC2_155 ARLAQRSALAVGRLG-GTGEQYSGDLMLAFSTGNRGIPPYAWDENVDTER
TH_1833|M.thermoresistible__bu ARLAQRSALGIARTG-GAGENGSGDMAFCFTTGN----TFAGDFAATAGP
Mflv_3141|M.gilvum_PYR-GCK RALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEASGLASAFPLGPPGED
Mvan_3384|M.vanbaalenii_PYR-1 KALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEVPDLASTFPLGPVGDD
:* .:.* : .** ::*.
Mb1368|M.bovis_AF2122/97 GVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR-DMFP
Rv1333|M.tuberculosis_H37Rv GVPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR-DMFP
MMAR_4065|M.marinum_M AIPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR-DVLP
MUL_3929|M.ulcerans_Agy99 AIPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR-DVLP
MAV_1553|M.avium_104 DTPAAFSPETRLATEVGAAAADCLAHAVLGGVLAADSVAGIPSYR-DVLP
MLBr_01167|M.leprae_Br4923 DVPVAMSPETGLITEVGAAADDCLARAVLVAVLAAESVAGIPTYC-GMFP
MAB_1477|M.abscessus_ATCC_1997 -----------LTAAVGIAAADCVERAVVRAVVGAASVAGIPAYR-DVLP
MSMEG_1507|M.smegmatis_MC2_155 PEIDVRMVAPQLMTRLFDLTIEATEEAILNVLVTAETLTGRDGRTAHALD
TH_1833|M.thermoresistible__bu DVVEVRMLANRLIDRLFYAAIEATEEAIVNALFAAETMEGPEGLVVTALP
Mflv_3141|M.gilvum_PYR-GCK ELGTISFLPWGRMDTVYAAVVQSVEEAVLNALVVNTDMVGRDGHRSPRLP
Mvan_3384|M.vanbaalenii_PYR-1 ELGSITFLPWGRMDDLYAAVVQCVEEAVLNALVVNTDMVGRDGHRSPRLP
: . :. .*:: :. : * :
Mb1368|M.bovis_AF2122/97 GAFGS------------
Rv1333|M.tuberculosis_H37Rv GAFGS------------
MMAR_4065|M.marinum_M GALQTSGTESR------
MUL_3929|M.ulcerans_Agy99 GALQTSGTESR------
MAV_1553|M.avium_104 GALGR------------
MLBr_01167|M.leprae_Br4923 GAFGTTIGGGNR-----
MAB_1477|M.abscessus_ATCC_1997 GAFS-------------
MSMEG_1507|M.smegmatis_MC2_155 HKLFRTALLLEDH----
TH_1833|M.thermoresistible__bu RE--QTAELLRRYRQLR
Mflv_3141|M.gilvum_PYR-GCK LD--RLTELLGGRP---
Mvan_3384|M.vanbaalenii_PYR-1 LD--RLPALLSRRP---