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IHRVTGIDFATTTPDGTSRARGVGIPFQGTPGPLNALTDVAGVEVGATTLIDGDGPLCVGAGPVRTGVTA ILPRGRDGVGQPCAAGWYSLNGNGEMTGTTWIDEVGSFNLPVVLSNTHAVGACHTGVVQWANRVAPRLGR QWLLPVCAETWDGYLNDINGGHVRPDHVEAALDAARGGPVAEGSVGGGTGMNCYDFKGGNGTASRIVPYG SRTYTVAAFVQANFGARAELTIAGRHVGPEMLDDNPLDGDWFARDLDGAPPGAGSVIAVIATDAPLLPGQ CRALARRVPLGLARTGTTGSHFSGDIFLAFSTAEASGLASAFPLGPPGEDELGTISFLPWGRMDTVYAAV VQSVEEAVLNALVVNTDMVGRDGHRSPRLPLDRLTELLGGRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3141 | - | - | 100% (393) | peptidase S58, DmpA |
| M. gilvum PYR-GCK | Mflv_2351 | - | 1e-10 | 28.77% (358) | peptidase S58, DmpA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1368 | - | 1e-09 | 31.88% (298) | hydrolase |
| M. tuberculosis H37Rv | Rv1333 | - | 1e-09 | 31.88% (298) | hydrolase |
| M. leprae Br4923 | MLBr_01167 | - | 1e-14 | 31.41% (312) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_1477 | - | 7e-09 | 28.25% (354) | hypothetical protein MAB_1477 |
| M. marinum M | MMAR_4065 | dmpA | 6e-11 | 26.76% (370) | L-aminopeptidase/D-esterase DmpA |
| M. avium 104 | MAV_1553 | - | 5e-10 | 28.72% (383) | peptidase family protein T4 |
| M. smegmatis MC2 155 | MSMEG_1507 | - | 1e-71 | 44.20% (362) | D-aminopeptidase |
| M. thermoresistible (build 8) | TH_1833 | - | 1e-75 | 44.50% (373) | D-aminopeptidase |
| M. ulcerans Agy99 | MUL_3929 | dmpA | 5e-11 | 26.76% (370) | L-aminopeptidase/D-esterase DmpA |
| M. vanbaalenii PYR-1 | Mvan_3384 | - | 0.0 | 86.55% (394) | peptidase S58, DmpA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1368|M.bovis_AF2122/97 ----------------------------------MNSITDVGGIRVGHYQ
Rv1333|M.tuberculosis_H37Rv ----------------------------------MNSITDVGGIRVGHYQ
MMAR_4065|M.marinum_M ----------------------------------MSSITDIGGIRVGHYQ
MUL_3929|M.ulcerans_Agy99 ----------------------------------MSSITDIGGIRVGHYQ
MAV_1553|M.avium_104 ----------------------------------MNAITDVGGIRVGHHQ
MLBr_01167|M.leprae_Br4923 ---------------------------MILMAAPMNSITDISGIQVGHYH
MAB_1477|M.abscessus_ATCC_1997 ------------------------------MSLFSGAITDVPGILVGHHQ
Mflv_3141|M.gilvum_PYR-GCK MIHRVTGIDFATTTPDGTSRARGVGIPFQGTPGPLNALTDVAGVEVGATT
Mvan_3384|M.vanbaalenii_PYR-1 MIHRVTATNLATHTPDGRPRARGAGIGFSGQPGPLNALTDVAGVQIGVTT
MSMEG_1507|M.smegmatis_MC2_155 ----------MADSPRKRVRNLGVVVGEHPT-GPYNAITDVAGVRVGHTT
TH_1833|M.thermoresistible__bu ---------------VARARDYGATIGVLPT-GPNNAITDVAGVRVGHTT
.::**: *: :*
Mb1368|M.bovis_AF2122/97 RLDPDASLGAG---WACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPA
Rv1333|M.tuberculosis_H37Rv RLDPDASLGAG---WACGVTVVLPPPGTVGAVDCRGGAPGTRETDLLDPA
MMAR_4065|M.marinum_M RLDPDASLGAG---WASGVTVVLAPPGTVGAVDCRGGAPGTRETDLLDPV
MUL_3929|M.ulcerans_Agy99 RLDPDASLGAG---WASGVTVVLAPPGTVGAVDCRGGAPGTRETDLLDPV
MAV_1553|M.avium_104 RLDPDASLGAG---WACGVTVVLTPPGTVGAVDCRGGAPGTRETDLLDPA
MLBr_01167|M.leprae_Br4923 RLDPDASLGAG---WACGVTVVLTPPGTVGAVDCRGGVPGTRETDLLDPA
MAB_1477|M.abscessus_ATCC_1997 RVDADASLGAG---WATGTTVVLAPPGTTGAVDVRGGAPGTRESDLLDPA
Mflv_3141|M.gilvum_PYR-GCK LIDGDGPLCVGAGPVRTGVTAILPRGRDGVGQPCAAGWYSLNGNGEMTGT
Mvan_3384|M.vanbaalenii_PYR-1 LIDGDGPLIVGQGPIRTGVTAILPRGRSGVGQPCAAGWYSLNGNGEMTGT
MSMEG_1507|M.smegmatis_MC2_155 IQDG--------AAVNTGVTVVVPHD-DIWGEPVFAGAHRLNGSGEMTGL
TH_1833|M.thermoresistible__bu LIEGSGPRVTGQGPVRTGVTVVIPRD-EPWNHPLFAAAHRLNGNGELTGQ
: *.*.::. .. . .. :
Mb1368|M.bovis_AF2122/97 NSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAV
Rv1333|M.tuberculosis_H37Rv NSVRFVDALLLAGGSAYGLAAADGVMRWLEEHRRGVAMDSGVVPIVPGAV
MMAR_4065|M.marinum_M NSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGAGVVPIVPGAV
MUL_3929|M.ulcerans_Agy99 NSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHQRGVAMGTGVVPIVPGAV
MAV_1553|M.avium_104 NTVRFVDAVLLAGGSAYGLAAADGVMRWLEEHDRGVAMDGGVVPIVPGAV
MLBr_01167|M.leprae_Br4923 NSVRFVDAVLLAGGSAYGLAAADGVMRWLEEHERGVVMLGGVVPIVPGAV
MAB_1477|M.abscessus_ATCC_1997 NTVATVDAVVLTGGSAYGLAAADGVMRWLEERGRGVPLSGGTVPIVPAAV
Mflv_3141|M.gilvum_PYR-GCK TWIDEVGSFNLPVVLSNTHAVGACHTGVVQWANRVAPRLGRQWLLPVCAE
Mvan_3384|M.vanbaalenii_PYR-1 TWIDEVGSFNLPVVLSNTHAVGACHTGVVRWANRVAPRLARQWLLPVCAE
MSMEG_1507|M.smegmatis_MC2_155 EWIRESGELTTAIGLTNTHSAGVVRDALVDAQVAARG-DGLYWSLPVVGE
TH_1833|M.thermoresistible__bu HWVEESGQLTSYIGLTNTHSVGVVRDALIAHEKNARGADEFFFALPVVGE
: . . : :.. : : .
Mb1368|M.bovis_AF2122/97 IFDLPVGGWN-CRPTADFGYSACAAAGVD--------VAVGTVGVGVGAR
Rv1333|M.tuberculosis_H37Rv IFDLPVGGWN-CRPTADFGYSACAAAGVD--------VAVGTVGVGVGAR
MMAR_4065|M.marinum_M IFDLPVGGWG-QRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGVGAR
MUL_3929|M.ulcerans_Agy99 IFDLPVGGWG-QRPTAEFGYLACDAAVSDQDPGATASLAVGTVGAGVGAR
MAV_1553|M.avium_104 IFDLPVGGWQ-CRPTAEFGYLACAAARDDD------APAVGTVGAGVGAR
MLBr_01167|M.leprae_Br4923 IFDLSVGDFH-CRPTAEFGYLACQAAYDAAVGGQDATVAVGTVGAGVGAR
MAB_1477|M.abscessus_ATCC_1997 IFDLPVGAWK-NRPDTEFGYRAAELADDAP--------EWGAVGAGAGAR
Mflv_3141|M.gilvum_PYR-GCK TWDGYLNDINGGHVRPDHVEAALDAARGGP-------VAEGSVGGGTGMN
Mvan_3384|M.vanbaalenii_PYR-1 TWDGYLNDINGGHVRPEHVEAALDAATAGP-------VAEGSVGGGTGMN
MSMEG_1507|M.smegmatis_MC2_155 TYDGLLNDINGHHVRAEHVHAALAAASDGP-------VAEGNVGGGTGMI
TH_1833|M.thermoresistible__bu TCDGILNDINGFHVKPEHVAAAIDAAADGP-------VPEGAVGGGTGMI
* :. : .:. * * * ** *.*
Mb1368|M.bovis_AF2122/97 AGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEF
Rv1333|M.tuberculosis_H37Rv AGALKGGVGTASATLQSGVTVGVLAVVNAAGNVVDPATGLPWMADLVGEF
MMAR_4065|M.marinum_M AGVLKGGVGTASVKLPSGVTVGAVVVVNSVGNVVDPATGLPWMAELSGEF
MUL_3929|M.ulcerans_Agy99 AGVLKGGVGTASVKLPSGVTVGAVVVVNSVGNVVDPATGLPWMAELSGEF
MAV_1553|M.avium_104 AGALKGGVGTASRSLPSGVTVGALAVVNSAGEVVDRATGLPWMTDLVEQF
MLBr_01167|M.leprae_Br4923 AGVLKGGVGTASITLESGPTVGAVVVVNSVGDVVDRATGLPWMTDLIDEF
MAB_1477|M.abscessus_ATCC_1997 AGTLKGGVGSASVNVGDGIVVGALVVANPVGLVINPATGRPWTADILPEL
Mflv_3141|M.gilvum_PYR-GCK CYDFKGGNGTASRIVPYG--SRTYTVAAFVQANFGARAELTIAGRHVGPE
Mvan_3384|M.vanbaalenii_PYR-1 CYEFKGGNGTASRLVPYG--RRTYTVAAFVQANFGSRAELTITGSHIGPQ
MSMEG_1507|M.smegmatis_MC2_155 CHGFKGGIGTASRVTDTA--AGRYTVGVLVQANHGRRERLRVNGVPVG-E
TH_1833|M.thermoresistible__bu AHGYKGGIGTSSRV------VGDYTVGVLVQANHGARERLTIDGVPVG-R
. *** *::* .* . .
Mb1368|M.bovis_AF2122/97 ALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAALSPAACR
Rv1333|M.tuberculosis_H37Rv ALRAPPAEQIAALAQLSSPLGAFNTP----FNTTIGVIACDAALSPAACR
MMAR_4065|M.marinum_M GLTRPPADQLDELARLPSPLDPQNAPQDRPLNTTIAVVATDAALSPAGCQ
MUL_3929|M.ulcerans_Agy99 GLTRPPADQLDELARLPSPLDPQDAPQDRPLNTTIAVVATDAALSPAGCQ
MAV_1553|M.avium_104 GLRPPPVEQIEAFAALPSPSNPLDNP----LNTVIAVVATDAALSAAACR
MLBr_01167|M.leprae_Br4923 ALRPPSPEQIAGFAQLKSPLSA--------LNTTIGVVATDATLSPAACQ
MAB_1477|M.abscessus_ATCC_1997 S--APPAAEIEKLRDLPDKSVS--------LNTTIGVVATNAALSKAQCR
Mflv_3141|M.gilvum_PYR-GCK MLDDNPLDGDWFARDLDGAPP--------GAGSVIAVIATDAPLLPGQCR
Mvan_3384|M.vanbaalenii_PYR-1 LMDDNPLDGDWFARDLAAAPPP-------GAGSVIAVVATDAPLLPGQCK
MSMEG_1507|M.smegmatis_MC2_155 VIGPEAVP----LPEMPRAYEP-------GSGSIIVIVATDAPLLPHQCA
TH_1833|M.thermoresistible__bu LL-PEPPS----PAAMPGRPPE-------GTGSIIVLVATDAPLIPTQCA
. : .: * ::* :*.* *
Mb1368|M.bovis_AF2122/97 RIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------AVPPEAG
Rv1333|M.tuberculosis_H37Rv RIAIAAHDGLARTIRPAHTPLDGDTVFALATGAV---------AVPPEAG
MMAR_4065|M.marinum_M RVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------QVPPDPA
MUL_3929|M.ulcerans_Agy99 RVAIAAQDGLARTIRPAHTPLDGDTVFALATGAV---------QVPPDPA
MAV_1553|M.avium_104 RVAVAAHDGLARSIRPAHTPVDGDTVFVLATGAV---------EVPPEAD
MLBr_01167|M.leprae_Br4923 RVAMAAQDGLARTIRPAHTALDGDTVFALATGAV---------EATATAD
MAB_1477|M.abscessus_ATCC_1997 RVAIAAHDGLARAIRPAHTPMDGDTLYVLATGTG---------EGDADP-
Mflv_3141|M.gilvum_PYR-GCK ALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEASGLASAFPLGPPGEDE
Mvan_3384|M.vanbaalenii_PYR-1 ALARRVPLGLARTG-TTGSHFSGDIFLAFSTAEVPDLASTFPLGPVGDDE
MSMEG_1507|M.smegmatis_MC2_155 RLAQRSALAVGRLG-GTGEQYSGDLMLAFSTGNRGIPPYAWDENVDTERP
TH_1833|M.thermoresistible__bu RLAQRSALGIARTG-GAGENGSGDMAFCFTTGN----TFAGDFAATAGPD
:* .:.* : .** ::*.
Mb1368|M.bovis_AF2122/97 VPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR-DMFPG
Rv1333|M.tuberculosis_H37Rv VPAALSPETQLVTAVGAAAADCLARAVLAGVLNAQPVAGIPTYR-DMFPG
MMAR_4065|M.marinum_M IPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR-DVLPG
MUL_3929|M.ulcerans_Agy99 IPAALSPETGLLTAVGAAAADCLAQAVLVGVIAAESVAGIPSYR-DVLPG
MAV_1553|M.avium_104 TPAAFSPETRLATEVGAAAADCLAHAVLGGVLAADSVAGIPSYR-DVLPG
MLBr_01167|M.leprae_Br4923 VPVAMSPETGLITEVGAAADDCLARAVLVAVLAAESVAGIPTYC-GMFPG
MAB_1477|M.abscessus_ATCC_1997 ----------LTAAVGIAAADCVERAVVRAVVGAASVAGIPAYR-DVLPG
Mflv_3141|M.gilvum_PYR-GCK LGTISFLPWGRMDTVYAAVVQSVEEAVLNALVVNTDMVGRDGHRSPRLPL
Mvan_3384|M.vanbaalenii_PYR-1 LGSITFLPWGRMDDLYAAVVQCVEEAVLNALVVNTDMVGRDGHRSPRLPL
MSMEG_1507|M.smegmatis_MC2_155 EIDVRMVAPQLMTRLFDLTIEATEEAILNVLVTAETLTGRDGRTAHALDH
TH_1833|M.thermoresistible__bu VVEVRMLANRLIDRLFYAAIEATEEAIVNALFAAETMEGPEGLVVTALPR
: . :. .*:: :. : * :
Mb1368|M.bovis_AF2122/97 AFGS------------
Rv1333|M.tuberculosis_H37Rv AFGS------------
MMAR_4065|M.marinum_M ALQTSGTESR------
MUL_3929|M.ulcerans_Agy99 ALQTSGTESR------
MAV_1553|M.avium_104 ALGR------------
MLBr_01167|M.leprae_Br4923 AFGTTIGGGNR-----
MAB_1477|M.abscessus_ATCC_1997 AFS-------------
Mflv_3141|M.gilvum_PYR-GCK D--RLTELLGGRP---
Mvan_3384|M.vanbaalenii_PYR-1 D--RLPALLSRRP---
MSMEG_1507|M.smegmatis_MC2_155 KLFRTALLLEDH----
TH_1833|M.thermoresistible__bu E--QTAELLRRYRQLR