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M. smegmatis MC2 155 MSMEG_2072 (-)

annotation: 3-hydroxy-3-methylglutaryl-CoA lyase
coordinates: 2148691 - 2149593
length: 300

DLPTHVDIREVCLRDGLQIEQPIPLSAKLEILEAIAATGVREIEATAFVSPSKVPALADAAELAAELHRF
PDVEFSALVASPNGAKRAIAAGLHSIEYVVSAADSHSKANVGRSSAEATAQIADIVAIAHDSDTSVEVII
ATAWDCPFDGPTDPQRVLDIVSAAVEYGADRLAVADTIGTTTPRRVTTLVQQVRPLIGDLPLGAHFHNTR
GAGLASAYAAVQAGITRLDASVGGLGGCPFAPGASGNIATEDLVYLLRDSDIGVDIDLRAAIEAARVAQR
AVGHDLPSALLRAGDRILG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_2072--100% (300)3-hydroxy-3-methylglutaryl-CoA lyase
M. smegmatis MC2 155MSMEG_2024-3e-5140.32% (253) hydroxymethylglutaryl-CoA lyase
M. smegmatis MC2 155MSMEG_6648pyc9e-0927.89% (190) pyruvate carboxylase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2991cpca3e-0730.83% (133) pyruvate carboxylase
M. gilvum PYR-GCKMflv_4466-1e-13983.28% (299) pyruvate carboxyltransferase
M. tuberculosis H37RvRv2967cpca3e-0730.83% (133) pyruvate carboxylase
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4650c-1e-12673.24% (299) putative pyruvate carboxyltransferase
M. marinum MMMAR_1493-1e-12674.32% (296) hypothetical protein MMAR_1493
M. avium 104MAV_4025-1e-12375.85% (294) pyruvate carboxyltransferase
M. thermoresistible (build 8)TH_4346-5e-4436.45% (299) PUTATIVE putative hydroxymethylglutaryl-CoA lyase
M. ulcerans Agy99MUL_2447-1e-12774.32% (296) hypothetical protein MUL_2447
M. vanbaalenii PYR-1Mvan_1894-1e-14083.95% (299) pyruvate carboxyltransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQ
Rv2967c|M.tuberculosis_H37Rv        MFSKVLVANRGEIAIRAFRAAYELGVGTVAVYPYEDRNSQHRLKADESYQ
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           IGDIGHPVHAYLSVDEIVATARRAGADAIYPGYGFLSENPDLAAACAAAG
Rv2967c|M.tuberculosis_H37Rv        IGDIGHPVHAYLSVDEIVATARRAGADAIYPGYGFLSENPDLAAACAAAG
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           ISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAG
Rv2967c|M.tuberculosis_H37Rv        ISFVGPSAEVLELAGNKSRAIAAAREAGLPVLMSSAPSASVDELLSVAAG
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           MPFPLFVKAVAGGGGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLE
Rv2967c|M.tuberculosis_H37Rv        MPFPLFVKAVAGGGGRGMRRVGDIAALPEAIEAASREAESAFGDPTVYLE
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           QAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIELAPAPHLDAE
Rv2967c|M.tuberculosis_H37Rv        QAVINPRHIEVQILADNLGDVIHLYERDCSVQRRHQKVIELAPAPHLDAE
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           LRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVT
Rv2967c|M.tuberculosis_H37Rv        LRYKMCVDAVAFARHIGYSCAGTVEFLLDERGEYVFIEMNPRVQVEHTVT
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           EEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRITTEDPANG
Rv2967c|M.tuberculosis_H37Rv        EEITDVDLVASQLRIAAGETLEQLGLRQEDIAPHGAALQCRITTEDPANG
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      -------------------------------------------VTVPSPV
Mb2991c|M.bovis_AF2122/97           FRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLP
Rv2967c|M.tuberculosis_H37Rv        FRPDTGRISALRTAGGAGVRLDGSTNLGAEISPYFDSMLVKLTCRGRDLP
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------MTELPTHVDIRDVSLRDG------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------MSELPGHVDIRDVSLRDG------------------
MSMEG_2072|M.smegmatis_MC2_155      ---------------MDLPTHVDIREVCLRDG------------------
MMAR_1493|M.marinum_M               -----------------MTTHVTIREVALRDG------------------
MUL_2447|M.ulcerans_Agy99           -----------------MTTHVTIREVALRDG------------------
MAV_4025|M.avium_104                ---------------------MAIREVALRDG------------------
MAB_4650c|M.abscessus_ATCC_199      ---------------MSLPEHVSIREVLLRDG------------------
TH_4346|M.thermoresistible__bu      APPSRDAAGSARPALPGLPDSIELVEVGLRDG------------------
Mb2991c|M.bovis_AF2122/97           TAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQL
Rv2967c|M.tuberculosis_H37Rv        TAVSRARRAIAEFRIRGVSTNIPFLQAVLDDPDFRAGRVTTSFIDERPQL
                                                         : : :. * *                   

Mflv_4466|M.gilvum_PYR-GCK          -----------------------------------------LQIED-PIP
Mvan_1894|M.vanbaalenii_PYR-1       -----------------------------------------LQIED-PIP
MSMEG_2072|M.smegmatis_MC2_155      -----------------------------------------LQIEQ-PIP
MMAR_1493|M.marinum_M               -----------------------------------------LQIEK-PVP
MUL_2447|M.ulcerans_Agy99           -----------------------------------------LQIEK-PVP
MAV_4025|M.avium_104                -----------------------------------------LQIEA-PIP
MAB_4650c|M.abscessus_ATCC_199      -----------------------------------------LQLET-PIA
TH_4346|M.thermoresistible__bu      -----------------------------------------LQAVTRPVP
Mb2991c|M.bovis_AF2122/97           LTARASADRGTKILNFLADVTVNNPYGSRPSTIYPDDKLPDLDLRAAPPA
Rv2967c|M.tuberculosis_H37Rv        LTARASADRGTKILNFLADVTVNNPYGSRPSTIYPDDKLPDLDLRAAPPA
                                                                             *:    * .

Mflv_4466|M.gilvum_PYR-GCK          LS---------------AKLELLASIAATGVTEMEATAFVSPSKVPALAD
Mvan_1894|M.vanbaalenii_PYR-1       LS---------------AKLELLAAIAATGVREMEATAFVSPSKVPALAD
MSMEG_2072|M.smegmatis_MC2_155      LS---------------AKLEILEAIAATGVREIEATAFVSPSKVPALAD
MMAR_1493|M.marinum_M               LS---------------AKLELLAAVAATGVREVEATAFVSPSKVPSMAD
MUL_2447|M.ulcerans_Agy99           LS---------------AKLELLAAVAATGVREVEATAFVSPSKVPSMAD
MAV_4025|M.avium_104                LS---------------AKLELLAAVAATGVREVEATAFVSPSKVPSMAD
MAB_4650c|M.abscessus_ATCC_199      LA---------------DKLKLLEAVAATGVREVEATAFVSPTKMPALAD
TH_4346|M.thermoresistible__bu      TA---------------EKVAIVEGLINAGFRTIEAVSFAHPKVLPQLAD
Mb2991c|M.bovis_AF2122/97           GSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATRVRTSGLSR
Rv2967c|M.tuberculosis_H37Rv        GSKQRLVKLGPEGFARWLRESAAVGVTDTTFRDAHQSLLATRVRTSGLSR
                                     :                :     .:  : .   .   :.     . :: 

Mflv_4466|M.gilvum_PYR-GCK          AAELAAELH----------------------------------NFPGIEF
Mvan_1894|M.vanbaalenii_PYR-1       AADLAAELR----------------------------------NFPDIEF
MSMEG_2072|M.smegmatis_MC2_155      AAELAAELH----------------------------------RFPDVEF
MMAR_1493|M.marinum_M               AAELAAELH----------------------------------SYPDIEF
MUL_2447|M.ulcerans_Agy99           AAELAAELH----------------------------------SYPDIEF
MAV_4025|M.avium_104                AADLAAHLA----------------------------------DYPDIEF
MAB_4650c|M.abscessus_ATCC_199      AAELAAQLH----------------------------------HYPDIEF
TH_4346|M.thermoresistible__bu      AEAVMAAVP----------------------------------RPPDVTY
Mb2991c|M.bovis_AF2122/97           VAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICL
Rv2967c|M.tuberculosis_H37Rv        VAPYLARTMPQLLSVECWGGATYDVALRFLKEDPWERLATLRAAMPNICL
                                    .    *                                       *.:  

Mflv_4466|M.gilvum_PYR-GCK          SALVASPNGAKRAIAAGLRSIEYVVSAADGHSRANVGRASAEATAQIAEI
Mvan_1894|M.vanbaalenii_PYR-1       SALVASPNGAKRAIAAGLRSIEYVVSAADGHSRANVGRSSAEATAQIPEI
MSMEG_2072|M.smegmatis_MC2_155      SALVASPNGAKRAIAAGLHSIEYVVSAADSHSKANVGRSSAEATAQIADI
MMAR_1493|M.marinum_M               SALVASPNGARRAIAAGLHAIEYVVAASNSFSMANVGRSTADATDQISEI
MUL_2447|M.ulcerans_Agy99           SALVASPNGARRAIAAGLHAIEYVVAASNSFSMANVGRSTADATDQISEI
MAV_4025|M.avium_104                SALVASPNGARRAVAAGLRAIEYVVAADDTFSAANVGRTSAEATEQIGDI
MAB_4650c|M.abscessus_ATCC_199      SALVASPNGAKRALAAGFTSLEYVVSAADGHSRANVGISSAEAIARIQEI
TH_4346|M.thermoresistible__bu      RGLVPNLRGAHRAVACGLDEWVLVVSADEEVSVRNQRRTVEQMLTELPGV
Mb2991c|M.bovis_AF2122/97           QMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALNNIESMRPA
Rv2967c|M.tuberculosis_H37Rv        QMLLRGRNTVGYTPYPEIVTSAFVQEATATGIDIFRIFDALNNIESMRPA
                                      *: . . .  :    :     *  *              :    :   

Mflv_4466|M.gilvum_PYR-GCK          TAIAHDSD---ASVEVIIATAWDCPFDGPTAPQRVIDIVTAATDAGADRM
Mvan_1894|M.vanbaalenii_PYR-1       VAIAHDSG---VSVEVIVATAWDCPFDGPTAPQRVVDIVTAAADGGVDRL
MSMEG_2072|M.smegmatis_MC2_155      VAIAHDSD---TSVEVIIATAWDCPFDGPTDPQRVLDIVSAAVEYGADRL
MMAR_1493|M.marinum_M               LAIGRDGE---VTVEVIVATAWDCPFDGAVAPQQVLDIAATAVGQGVDRF
MUL_2447|M.ulcerans_Agy99           LAIGRDGE---VTVEVIVATAWDCPFDGAVAPQQVLDIAATAVDQGVDRF
MAV_4025|M.avium_104                VAIAHDGPGPPVTVEVVIATAWDSPFEGPTPPQRVLDIAAAARDRGADRL
MAB_4650c|M.abscessus_ATCC_199      VTLARGAD---ATVEVIVACSWDCPFDGPTAQKRVLDIMQRARDWGADRY
TH_4346|M.thermoresistible__bu      AALARESG---VRLIVAVACAFFAPARGPVPRQEYLRVVDAAVDTGVDAL
Mb2991c|M.bovis_AF2122/97           IDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVL
Rv2967c|M.tuberculosis_H37Rv        IDAVRETGSAIAEVAMCYTGDLTDPGEQLYTLDYYLKLAEQIVDAGAHVL
                                        :      . : :  :     *       .  : :       *..  

Mflv_4466|M.gilvum_PYR-GCK          AIADTIGTATPRRVGDLIALVRPLVGDTPLGAHFHNTRGAGLASAFAAVS
Mvan_1894|M.vanbaalenii_PYR-1       AIADTIGTATPRRVSDLIGMVRPRIVDIPLGAHFHNTRGAGLASAYAAVS
MSMEG_2072|M.smegmatis_MC2_155      AVADTIGTTTPRRVTTLVQQVRPLIGDLPLGAHFHNTRGAGLASAYAAVQ
MMAR_1493|M.marinum_M               SIADTIGTATPGRVSALIAQLGPVLGDMPLGAHFHNTRGSGLASAYAAVC
MUL_2447|M.ulcerans_Agy99           SIADTIGTATPGRVSALIAQLGPVLGDMPLGAHFHNTRGSGLASAYAAVC
MAV_4025|M.avium_104                SIADTIGTATPGRVSSLIAQLLPVIGDMPLGGHFHNTRGCGLASAYAAVG
MAB_4650c|M.abscessus_ATCC_199      ALADTIGTATPRRVANLIAAVRSIIGDAPLGAHFHNTRGSGLASAYAAVQ
TH_4346|M.thermoresistible__bu      YLACTTGQEHPGEVAERVGEVRRRHPAVRVGVHLHNRNGFAAANAIAAMQ
Mb2991c|M.bovis_AF2122/97           AIKDMAGLLRPPAAQRLVSALRSRF-DLPVHLHTHDTPGGQLASYVAAWH
Rv2967c|M.tuberculosis_H37Rv        AIKDMAGLLRPPAAQRLVSALRSRF-DLPVHLHTHDTPGGQLASYVAAWH
                                     :    *   *  .   :  :        :  * *:  *   *.  **  

Mflv_4466|M.gilvum_PYR-GCK          AGVTRLDASVGGLGGCPFAPG---ASGNIAVEDLVYLLRDSGIHTEVDLD
Mvan_1894|M.vanbaalenii_PYR-1       AGVTRLDASVGGLGGCPFAPG---ASGNIAVEDLVYLLRDSGIHVDVDLE
MSMEG_2072|M.smegmatis_MC2_155      AGITRLDASVGGLGGCPFAPG---ASGNIATEDLVYLLRDSDIGVDIDLR
MMAR_1493|M.marinum_M               SGVTRLDASVGGLGGCPFAPG---ATGNIATEDLVYLLADSGFAVDVDLA
MUL_2447|M.ulcerans_Agy99           SGVTRLDASVGGLGGCPFAPG---ATGNIATEDLVYLLADSGFAVDVDLA
MAV_4025|M.avium_104                AGVTRLDASVGGLGGCPFAPG---ATGNIATEDLVYLLTDSGFDVDVDLQ
MAB_4650c|M.abscessus_ATCC_199      SGVTRLDSSIGGLGGCPFAPG---ATGNIATEDLAYLLRDSDVNVDINLD
TH_4346|M.thermoresistible__bu      AGAAWLEGSFCGLGGDLWFPGDPSVLGNAPMEDLIHLCDALGVRTGISLP
Mb2991c|M.bovis_AF2122/97           AGADAVDGAAAPLAGTTSQPA---LSSIVAAAAHTEYDTGLSLSAVCALE
Rv2967c|M.tuberculosis_H37Rv        AGADAVDGAAAPLAGTTSQPA---LSSIVAAAAHTEYDTGLSLSAVCALE
                                    :*   ::.:   *.*    *.     .  .           .. .   * 

Mflv_4466|M.gilvum_PYR-GCK          AAIAAARVAQDVVGHSLP----------------------SSLLRAGDRI
Mvan_1894|M.vanbaalenii_PYR-1       SAIEAARVAQDAVGHELP----------------------SSLLRAGDRI
MSMEG_2072|M.smegmatis_MC2_155      AAIEAARVAQRAVGHDLP----------------------SALLRAGDRI
MMAR_1493|M.marinum_M               AAIAAAEVAKAVVGHDLP----------------------GALLRAGDRI
MUL_2447|M.ulcerans_Agy99           AAIAAAEVAKAVVGHDLP----------------------GALLRAGDRI
MAV_4025|M.avium_104                AAIAAAGVAKTLVGHDLP----------------------SALLRAGDRR
MAB_4650c|M.abscessus_ATCC_199      AAIAAAQIVQEVVGHEVP----------------------SALLRAGDRL
TH_4346|M.thermoresistible__bu      DYLDVARLAEQLTGVPTT----------------------AFVARGGSRH
Mb2991c|M.bovis_AF2122/97           PYWEALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRF
Rv2967c|M.tuberculosis_H37Rv        PYWEALRKVYAPFESGLPGPTGRVYHHEIPGGQLSNLRQQAIALGLGDRF
                                        .   .        .                      .     *.* 

Mflv_4466|M.gilvum_PYR-GCK          LG------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       LG------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      LG------------------------------------------------
MMAR_1493|M.marinum_M               RS------------------------------------------------
MUL_2447|M.ulcerans_Agy99           RS------------------------------------------------
MAV_4025|M.avium_104                RS------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      LN------------------------------------------------
TH_4346|M.thermoresistible__bu      DLATAQWSETV---------------------------------------
Mb2991c|M.bovis_AF2122/97           EEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSADEFASDPAR
Rv2967c|M.tuberculosis_H37Rv        EEIEEAYAGADRVLGRLVKVTPTSKVVGDLALALVGAGVSADEFASDPAR
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           FGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIA
Rv2967c|M.tuberculosis_H37Rv        FGIPESVLGFLRGELGDPPGGWPEPLRTAALAGRGAARPTAQLAADDEIA
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           LSSVGAKRQATLNRLLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGE
Rv2967c|M.tuberculosis_H37Rv        LSSVGAKRQATLNRLLFPSPTKEFNEHREAYGDTSQLSANQFFYGLRQGE
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           EHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVRDRSIAS
Rv2967c|M.tuberculosis_H37Rv        EHRVKLERGVELLIGLEAISEPDERGMRTVMCILNGQLRPVLVRDRSIAS
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       --------------------------------------------------
MSMEG_2072|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1493|M.marinum_M               --------------------------------------------------
MUL_2447|M.ulcerans_Agy99           --------------------------------------------------
MAV_4025|M.avium_104                --------------------------------------------------
MAB_4650c|M.abscessus_ATCC_199      --------------------------------------------------
TH_4346|M.thermoresistible__bu      --------------------------------------------------
Mb2991c|M.bovis_AF2122/97           AVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEA
Rv2967c|M.tuberculosis_H37Rv        AVPAAEKADRGNPGHIAAPFAGVVTVGVCVGERVGAGQTIATIEAMKMEA
                                                                                      

Mflv_4466|M.gilvum_PYR-GCK          -------------------------------
Mvan_1894|M.vanbaalenii_PYR-1       -------------------------------
MSMEG_2072|M.smegmatis_MC2_155      -------------------------------
MMAR_1493|M.marinum_M               -------------------------------
MUL_2447|M.ulcerans_Agy99           -------------------------------
MAV_4025|M.avium_104                -------------------------------
MAB_4650c|M.abscessus_ATCC_199      -------------------------------
TH_4346|M.thermoresistible__bu      -------------------------------
Mb2991c|M.bovis_AF2122/97           PITAPVAGTVERVAVSDTAQVEGGDLLVVVS
Rv2967c|M.tuberculosis_H37Rv        PITAPVAGTVERVAVSDTAQVEGGDLLVVVS